• 한국광학회지
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• 제17권3호
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• pp.285-289
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• 2006

광섬유형 콜리메이터와 광 진행 경로의 수직 방향으로 삽입된 주기적으로 식각된 줄무늬(stripe) 평판에 의해 진행하는 빔의 일부에 광 경로차를 유도하는 마이크로 옵틱형 마하젠더 간섭형 필터를 제안하고 구현하였다. 제안된 마이크로 옵틱 필터는 주기적으로 식각된 줄무늬(stripe) 구조의 평판을 빔 경로에 삽입하여 측방향 정렬에 무관하게 특정 소멸비 값 이상의 특성을 구현할 수 있으며, 식각된 박막의 두께를 조정함으로써 원하는 대역폭 및 주기의 전달특성을 가지는 필터를 구현할 수 있다. 네거티브 포토레지스터인 SU-8을 기반으로 줄무늬(stripe) 구조의 주기적으로 식각된 평판을 제작하였으며 이를 이용하여 구현된 필터의 소멸비는 측방향 정렬에 무관하게 30 dB이상의 값을 가진다. 제작된 필터의 FSR(Free Spectral Range)은 장파장 대역에서 약 237 nm이고 그리고 삽입손실은 2 dB 미만의 값을 가진다. 통과대역에서의 PDL(Polarisation Dependent Loss)값은 0.15 dB 미만이다.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2000년도 The 7th International Symposium
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• pp.34-51
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• 2000

Narcotic drugs generally refer to serious and habitual hidden rash such as opium, heroin, methyphetamin, nabinol, cocaine, and so forth. At present, narcotic drugs are spread unchecked and are causing a big social problem. So many countries and narcotists are making every effort to set up a barricade against narcotic drugs. And there is a limit suitable treatment for them. Thus Tuo Yin Tang hang is developed. As indicated by Chinese letters, Tuo yin Tang Jiang(TYTJ) is a crude drug. It is a traditional chinese medicine developed by the study done from lune in 1998 to lune in 1999 that Hubeisheng was entrusted with by People's Republic of China. This study is a treatise on etiology and syntomatology or narcotism. TYTJ is a medicine which is in accord with Pharmacopeia of the People's Republic of China in order to remove from the body the toxic materials resulting from narcotic drugs such as opium and heroin. According to the standard diagnosis on narcotism, 105 cases are studied and treated at the Rehabilitation Center attached to Enshi Autonomous Region Hospital in Hubeisheng. 105 cases are divided into 2 groups by double-blind method. One is the experimental group which has 56 cases. The other is the control group which has 49 ones. 13 cases among 105 cases are addicted by intravenously injections. 9 cases are by oral takings. It took 10 days for this experiment to be performed. Two groups didn't show a striking individual variation based on the age, gender, period of taking drugs, withdrawal symptoms, complication, and state of health. The experimental group had a higher effect of treatment than the control group had. TYTJ treats diseases effectively and has no side effect, irrespective of the serious or slight addiction to opium and morphine.

• 사상체질의학회지
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• 제24권3호
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• pp.34-41
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• 2012

Objectives In this study, we developed a mock-up of the system for Sasang Constitutional (SC) diagnosis. This system consists of 5 devices which are the face analyzer, the voice analyzer, the skin analyzer, the pulse analyzer, and the computer-based questionnaire. Our goal is to evaluate the repeatability of the system. Methods Each device is capable of classifying SC types. The classification probability of the integrated system for the SC types was obtained by summing the probability from each device. For evaluating the repeatability of the system, we collected data for 5 subjects, and repeated the measurement three times for each individual. The average and standard deviation were used for calculating the Coefficient of Variation. Results The results showed that the repeatability of the classification probability of the integrated system is about 8%, which implies the system is repeatable. Conclusions To increase usability of this system, it is desirable for the system to offer information on health condition of the user. The integrated constitutional diagnosis system will be upgraded to complement the convenience and to develop the diagnostic algorithm for the user's health condition.

• Journal of the Korean Wood Science and Technology
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• 제20권2호
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• pp.51-60
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• 1992

This study was performed to investigate the effect of green sorting before drying on the high-temperature drying characteristics of southern yellow pine dimension lumber(2"${\times}$6"${\times}$12'). To test the advantages of weight sorting, green lumber was seperated into heavy(above 55 1b), medium(50-55 1b), and light(below 50 1b)weight classes. Pieces in each weight class were subgrouped into high(above 35%) and low(below 30%) latewood groups. Groups were dried and seperated by a standard commercial high-temperature schedule; dry bulb temperature $245^{\circ}$ F, wet bulb temperature $180^{\circ}$ F, and air velocity 1200fpm. The results obtained were as follows; 1. There was a highly significant correlation between annual rings per inch(X) and percent-latewood(Y). The regression equation was Y=24, 5047+1.3272X. 2. There were highly significant correlations between either annual rings per inch($X_1$) or percent-latewood($X_2$) a.d specific gravity in green wood(Y). Their regression equations were Y=0.4260+0.0081$X_1$ and Y=0.3749+0.0029$X_2$, respectively. 3. Heavier weight charges dried more slowly than lighter weight charges. 4. Board-to-board variation in green or dry moisture content was less for all seperate weight classes than for unseperated control charges. 5. Lower latewood pieces had higher initial moisture content than higher latewood pieces, and then drying time for lower late wood pieces was longer than higher latewood pieces.

• 종양간호연구
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• 제10권2호
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• pp.210-217
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• 2010

Purpose: This survey was aimed to examine the current dietary restrictions practices for neutropenic patients among hospitals with 500 and more beds. Methods: Self-administered questionnaires were sent to 100 head or charge nurses of oncology or hemato-oncology wards by mail during October 2009, and 51 questionnaires were returned. The data were analyzed with descriptive statistics using SPSS (WIN version 12.0). Results: Of the hospitals surveyed, 47.1% (n=24) had guidelines on the dietary restrictions, and 80.4% (n=41) placed patients with neutropenia on restricted diets. The major decisional criteria of the dietary restriction was absolute neutrophil count (30.5%) and cooking status (29.2%). The most commonly restricted foods were raw fish or fresh meat (98.0%), uncooked intestine (98.0%), raw eggs (98.0%), draught beer (96.1%), and fresh fruits or vegetables (86.3%). Conclusion: The results showed variation in pattern of dietary restrictions and lower rate of guideline among hospitals, so that the need for the standard dietary restriction guideline is high. However, the role of diet in the development of infection in neutropenic patients is still unclear, which makes it difficult to establish dietary restriction guideline. Therefore, additional research are required to identify the relationship between dietary factors and infections.

• Journal of Applied Biological Chemistry
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• 제59권4호
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• pp.361-364
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• 2016

본 연구에서는 3-ethyl ascorbic acid를 표준물질로 이용하여, 폴리에톡시레이티드 아스코르빈산의 정량법을 개발하였고, 확립된 시험법으로 시중에서 돼지 및 닭의 면역력 증진과 열에 대한 스트레스 경감제로 유통되고 있는 Poustin-C 검체 내 폴리에톡시레이티드 아스코르빈산의 함량 분석을 실제로 분석하여 시험법의 유효성을 검증하였다. 개발한 분석법의 검증은 직선성, 정확성, 정밀성 및 안정성 시험 등을 통하여 평가하였다. 정밀도 시험은 일내 정밀성과 일간 정밀성으로 나누어 확인하였는데, 일내 및 일간 정밀성은 모두 3.4 % 이내로 매우 우수하였다. 그리고 직선성 실험에서는 상관계수($r^2$)가 0.998 이상으로 우수하였다. 실온에서 6시간까지는 안정하여 실험 도중 분해되지 않음을 확인하였다. 따라서 본 연구에서 개발된 시험법은 검체 내 폴리에톡시레이티드 아스코르빈산의 함량을 분석하기 위한 공정 시험법으로 활용할 수 있을 것으로 사료된다.

• 한국방재학회 논문집
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• 제6권4호통권23호
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• pp.49-56
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• 2006

도시지역의 우수를 배제하기 위한 방법으로 토구를 이용하여 하천으로 방류하고 있다. 그러나 이러한 토구를 설치 할 때 국내설계기준에는 어떠한 기준이나 제안이 없이 설계자나 시공자의 임의로 만들어 지고 있는 실정이다. 본 연구에서는 토구를 설치하는 방법에 대한 기초적인 자료를 제공하기 위하여 토구 방류 유량에 따른 흐름 변화 및 설치 각도, 돌출정도, 그리고 설치 위치에 따른 흐름변화를 실험을 통하여 분석함으로써 흐름에 보다 영향을 적게 미치는 토구설치 방법을 제안하였다. 총 10가지 경우에 대한 실험을 통하여, 같은 유량을 방류함에 있어서 한 곳으로의 방류보다는 상.하류 등으로 분리하여 방류하는 것이 흐름에 영향을 적게 미치는 것으로 나타났으며, 설치 각도 및 돌출에 따라 상류지역의 수위 상승 및 유속 감소 등의 현상이 나타나 토구 설치 시 보다 신중하고 흐름에 방해가 되지 않는 방향으로 설치할 수 있는 방안을 강구해야 한다.

• 약학회지
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• 제52권2호
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• pp.93-100
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• 2008

A liquid chromatographic method with tandom spectrometric detection (LC/MS/MS) for the simultaneous determination of doxifluridine and its active metabolite, 5-fluorouracil (5-FU) was developed over the concentration range of $5{\sim}2000$ ng/ml, respectively. Doxifluridine, 5-FU and internal standard, 5-chlorouracil (5-CU), were extracted from liver and intestine tissue via protein precipitation. Acetonitrile was used as the extraction solvent and the supernatant was evaporated and reconstructed in mobile phase. Optimum chromatographic separation was achieved on a Agilent Zorbax $C_{18}$ ($100\;mm{\times}2.1\;mm$, $3.5\;{\mu}m$) column with mobile phase run in isocratic with methanol : water (20 : 80, v/v). The flow rate was 0.2 ml/min with total cycle time of 5 min. The lower limit of quantification was validated at 5.0 ng/ml of liver and intestine tissue, for both doxifluridine and 5-FU, respectively. The intra-day and inter-day precision and accuracy of quality control (QC) samples were <11% coefficient of variation and <7% relative error from theoretical concentration for both analytes. In addition, the special designed stability study was performed, because the metabolism of doxifluridine occurs spontaneously even in ice bath for monkey liver. The stability of doxifluridine in liver and intestine of monkey and beagle dog was compared. It was found that bioanalytical validation could not be performed for the monkey liver; however, beagle dog's liver has relatively low speed of metabolism compared to monkey liver and instead of monkey liver, beagle dog's liver could be used for the validation. Bioanalytical validation could be performed in monkey intestine. Eventually, this developed method for liver and intestine will be useful in support of the toxicokinetic and pharmacokinetic studies of doxifluridine and 5-FU.

• Journal of the Korean Data and Information Science Society
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• 제21권6호
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• pp.1021-1029
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• 2010

중소기업의 조사부담 완화를 위하여 2009년부터 기존의 "중소기업실태조사", "중소기업인력실태 조사" 및 "중소기업사업전환실태조사"를 통합하여 하나의 조사로 수행하게 되었다. 통합 중소기업실태조사를 위한 새로운 표본설계에서 중소제조업과 지식기반서비스업 부문이 너무 상이하므로 별개의 모집단을 구성하였으며, 전체 표본수는 10,000개로 하였다. 변동계수를 사용한 배분공식으로 1차 층인 종사자규모 산업분류별로 표본을 배분하고 루트비례배분을 사용하여 2차 층인 지역별로 표본의 크기를 결정하였다. 새로운 표본설계에서는 가중치를 계산하였고 이를 이용한 추정량과 추정오차 공식을 유도하여 기존의 단순집계를 벗어나 종사자 규모별, 업종별 그리고 지역별 추정과 추정의 정도에 대한 평가를 가능하게 하였다.

• Imaging Science in Dentistry
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• 제48권2호
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• pp.121-125
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• 2018

Purpose: Detecting laryngeal cartilages (triticeous and thyroid cartilages) on panoramic radiographs is important because they may be confused with carotid artery calcifications in the bifurcation region, which are a risk factor for stroke. This study assessed the efficiency of panoramic radiography in the diagnosis of calcified laryngeal cartilages using cone-beam computed tomography (CBCT) as the reference standard. Materials and Methods: A total of 312 regions(142 bilateral, 10 left, 18 right) in 170 patients(140 males, 30 females) were examined. Panoramic radiographs were examined by an oral and maxillofacial radiologist with 11 years of experience. CBCT scans were reviewed by 2 other oral and maxillofacial radiologists. The kappa coefficient(${\kappa}$) was calculated to determine the level of intra-observer agreement and to determine the level of agreement between the 2 methods. Diagnostic indicators(sensitivity, specificity, accuracy, and false positive and false negative rates) were also calculated. P values <.05 were considered to indicate statistical significance. Results: Eighty-two images were re-examined to determine the intra-observer agreement level, and the kappa coefficient was calculated as 0.709 (P<.05). Statistically significant and acceptable agreement was found between the panoramic and CBCT images (${\kappa}=0.684$ and P<.05). The sensitivity, specificity, diagnostic accuracy rate, the false positive rate, and the false negative rate of the panoramic radiographs were 85.4%, 83.5%, 84.6%, 16.5%, and 14.6%, respectively. Conclusion: In most cases, calcified laryngeal cartilages could be diagnosed on panoramic radiographs. However, due to variation in the calcifications, diagnosis may be difficult.