• Journal of the Korean Association of Geographic Information Studies
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• v.23 no.3
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• pp.146-160
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• 2020

In the 4th industrial revolution, research on solving urban problems using ICT technology is emerging. Representatively, research is being conducted mainly focusing on smart cities. 3D geo-spatial. Various case studies on smart cities are being conducted to solve urban problems, and in order to effectively implement smart cities, it is implemented on the basis of a digital twin interconnecting physical and virtual environments. To implement a digital twin, the concept of space is essential, and spatial information that composes the real world is also essential. Therefore, in order to implement the digital twin, this study conducted a study on the construction and modeling of 3D geo-spatial information based on the national spatial information establishment regulations and the international standard CityGML for buildings, water facilities, and transportation facilities in Jeonju. In Jeonju, the research area, the LOD was defined, and the possibility of digital twin based on geo-spatial information was determined through data collection, analysis, and construction for each detail. In this study, it is meaningful that a plan to construct geo-spatial information for the implementation of a digital twin is presented, and the result of the construction is modeled as an urban standard model. The results of study are expected to be used as reference for detailed construction plans and standard establishment by governments and local governments promoting smart city and digital twin construction in the future.

• KIPS Transactions on Computer and Communication Systems
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• v.8 no.2
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• pp.41-56
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• 2019

Cloud manufacturing is a new concept of manufacturing process that works like a single factory with connected multiple factories. The cloud manufacturing system is a kind of large-scale CPS that produces products through the collaboration of distributed manufacturing facilities based on technologies such as cloud computing, IoT, and virtualization. It utilizes diverse and distributed facilities based on centralized information systems, which allows flexible composition user-centric and service-oriented large-scale systems. However, the cloud manufacturing system is composed of a large number of highly heterogeneous subsystems. It has difficulties in interconnection, data exchange, information processing, and system verification for system construction. In this paper, we derive the user requirements of various aspects of the cloud manufacturing system, such as functional, human, trustworthiness, timing, data and composition, based on the CPS Framework, which is the analysis methodology for CPS. Next, by analyzing the user requirements we define the system requirements including scalability, composability, interactivity, dependability, timing, interoperability and intelligence. We map the defined CPS system requirements to the requirements of oneM2M, which is the platform standard for IoT, so that the support of the system requirements at the level of the IoT platform is verified through Mobius, which is the implementation of oneM2M standard. Analyzing the verification result, finally, we propose a large-scale cloud manufacturing platform based on oneM2M that can meet the cloud manufacturing requirements to support the overall features of the Cloud Manufacturing CPS with dependability.

• Clinical and Experimental Pediatrics
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• v.51 no.1
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• pp.33-41
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• 2008

Purpose : It is now understood that blood pressure (BP) measurement in the routine pediatric examination is very important because of the relevance of childhood BP to pediatric health care and the development of adult essential hypertension. There hasn't been a reference table of BP for Korean children and adolescents up to now. This study was to make normative BP references and to provide criteria of hypertension for Korean children and adolescents. Methods : BP measurements were done on 57,433 Koean children and adolescents (male: 29,443, female: 27,990), aged 7 to 20 years, in 2005. Heights and weights were measured simultaneously. Oscillometric devices, Dinamap Procare 200 (GE Inc., Milwaukee, Wi, USA), were used for the measurements. BPs were measured 2 times and mean levels were gathered for the analysis. Outliers of 2,373 subjects with overweight per height, over ＋3SD, were excluded for the analysis. For the BP centiles adjusted by sex, age and height, fixed modified LMS method which was adopted from the mixed effect model of 2004 Task Force in NHLBI (USA) was used. Results : Normative BP tables for Korean children and adolescents adjusted for height percentiles (5th, 10th, 25th, 50th, 75th, 90th, 95th), gender (male, female) and age(7 to 18 years) were completed. Height centiles of Korean children and adolescents are available from Korean Center for Disease Control and Prevention homepage, http://www.cdc.go.kr/webcdc/. Criteria of hypertension (95th, 99th percentile) and normal range of BP (50th, 90th) adjusted for height percentiles, age and gender were made. Conclusion : This is the first study to make normative BP tables and define hypertension for the Korean children and adolescents. Reliability and accuracy of Dinamap Procare 200 oscillometer for BP measurements remains debatable.

• Korean Journal of Radiology
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• v.23 no.3
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• pp.322-332
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• 2022

Objective: CT plays a central role in determining the resectability of pancreatic cancer, which directs the use of neoadjuvant therapy. This study aimed to assess the diagnostic accuracy of CT in predicting circumferential resection margin (CRM) involvement in patients with resectable or borderline resectable pancreatic head cancer. Materials and Methods: Seventy-seven patients who were scheduled for upfront surgery for resectable or borderline resectable pancreatic head cancer were prospectively enrolled, and 75 patients (38 male and 37 female; mean age ± standard deviation, 68 ± 11 years) were finally analyzed. The CRM status was evaluated separately for the superior mesenteric artery (SMA) and posterior and superior mesenteric vein/portal vein (SMV/PV) margins. Three independent radiologists reviewed the preoperative CT images and evaluated the resection margin status. The reference standard for CRM status was pathologic examination of pancreaticoduodenectomy specimens in an axial plane perpendicular to the axis of the second portion of the duodenum. The diagnostic accuracy of CT was assessed for overall CRM involvement, defined as involvement of the SMA or posterior margins (per-patient analysis), and involvement of each of the three resection margins (per-margin analysis). The data were pooled using a crossed random effects model. Results: Forty patients had pathologically confirmed overall CRM involvement in pancreatic cancer, while CRM involvement was not seen in 35 patients. For overall CRM involvement, the pooled sensitivity and specificity were 15% (95% confidence interval: 7%-49%) and 99% (96%-100%), respectively. For each of the resection margins, the pooled sensitivity and specificity were 14% (9%-54%) and 99% (38%-100%) for the SMA margin, 12% (8%-46%) and 99% (97%-100%) for the posterior margin; and 37% (29%-53%) and 96% (31%-100%) for the SMV/PV margin, respectively. Conclusion: CT showed very high specificity but low sensitivity in predicting pathological CRM involvement in pancreatic cancer.

• IMMUNE NETWORK
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• v.4 no.3
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• pp.131-142
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• 2004

In recent years, adjuvants have received much attention because of the development of purified subunit and synthetic vaccines which are poor immunogens and require adjuvants to evoke the immune response. Therefore, immunologic adjuvants have been developed and testing for most of this century. During the last years much progress has been made on development, isolation and chemical synthesis of alternative adjuvants such as derivatives of muramyl dipeptide, monophosphoryl lipid A, liposomes, QS-21, MF-59 and immunostimulating complexes (ISCOMS). Biodegradable polymer microspheres are being evaluated for targeting antigens on mucosal surfaces and for controlled release of vaccines with an aim to reduce the number of doses required for primary immunization. The most common adjuvants for human use today are aluminum hydroxide and aluminum phosphate. Calcium phosphate and oil emulsions have been also used in human vaccination. The biggest issue with the use of adjuvants for human vaccines is the toxicity and adverse side effects of most of the adjuvant formulations. Other problems with the development of adjuvants include restricted adjuvanticity of certain formulations to a few antigens, use of aluminum adjuvants as reference adjuvant preparations under suboptimal conditions, non-availability of reliable animal models, use of non-standard assays and biological differences between animal models and humans leading to the failure of promising formulations to show adjuvanticity in clinical trials. The availability of hundreds of different adjuvants has prompted a need for identifying rational standards for selection of adjuvant formulations based on safety and sound immunological principles for human vaccines. The aim of the present review is to put the recent findings into a broader perspective to facilitate the application of these adjuvants in general and experimental vaccinology.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.182-185
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• 2005

Satellite cameras are calibrated before launch in detail and in general, but it cannot be guaranteed that the geometry is not changing during launch and caused by thermal influence of the sun in the orbit. Modem satellite imaging systems are based on CCD-line sensors. Because of the required high sampling rate the length of used CCD-lines is limited. For reaching a sufficient swath width, some CCD-lines are combined to a longer virtual CCD-line. The images generated by the individual CCD-lines do overlap slightly and so they can be shifted in x- and y-direction in relation to a chosen reference image just based on tie points. For the alignment and difference in scale, control points are required. The resulting virtual image has only negligible errors in areas with very large difference in height caused by the difference in the location of the projection centers. Color images can be related to the joint panchromatic scenes just based on tie points. Pan-sharpened images may show only small color shifts in very mountainous areas and for moving objects. The direct sensor orientation has to be calibrated based on control points. Discrepancies in horizontal shift can only be separated from attitude discrepancies with a good three-dimensional control point distribution. For such a calibration a program based on geometric reconstruction of the sensor orientation is required. The approximations by 3D-affine transformation or direct linear transformation (DL n cannot be used. These methods do have also disadvantages for standard sensor orientation. The image orientation by geometric reconstruction can be improved by self calibration with additional parameters for the analysis and compensation of remaining systematic effects for example caused by a not linear CCD-line. The determined sensor geometry can be used for the generation? of rational polynomial coefficients, describing the sensor geometry by relations of polynomials of the ground coordinates X, Y and Z.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.24 no.4
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• pp.133-152
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• 2013

This study strives to perform a pilot collection assessment study with the political science collection in a university library. Employing the basic list-checking analysis method, the study scrutinized the collection statistics and the circulation statistics, and check the current library holdings with a standard list which was composed of cited works extracted from course syllabi, theses, dissertations and faculty research papers. Although the study is a pilot case study that a particular model was applied to a collection in the field of political science, the result and procedures of the assessment will provide some implications regarding collection assessment in university libraries.

• Journal of Preventive Medicine and Public Health
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• v.41 no.3
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• pp.159-164
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• 2008

Objectives : The purpose of this systematic review was to investigate the association between dietary intake of citrus fruits and prostate cancer risk. Methods : Authors searched electronic databases and the reference lists of publications of diet and prostate cancer studies until August 2007. All of the epidemiological studies that obtained individual data on dietary intake of citrus fruits and presented risk estimates of the association between intake of citrus fruits and risk of prostate cancer were identified and included. Using general variance-based methods, study-specific odds ratios (OR)/ relative risk (RR) and associated confidence interval (CI)/ standard error (SE) for highest versus lowest intake of citrus fruits level were extracted from each paper. Results : Eleven articles including six case-control studies, one nested case-control study and four cohort studies, proved eligible. Overall summary OR using random effect model did not show an association in risk of prostate caner with intake of citrus fruits (summary OR=1.03, 95% CI=0.89-1.19) with large heterogeneity across studies that we were unable to explain ($I^2$=67.88%). The summary ORs in case-control studies and cohort studies were 1.10 (95% CI=0.97-1.22) and 1.05 (95% CI=0.96-1.14), respectively. Conclusions : Pooled results from observational studies did not show an association between intake of citrus fruits and the risk of prostate cancer, although results vary substantially across studies.

• Journal of Convergence for Information Technology
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• v.9 no.12
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• pp.39-46
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• 2019

The competition for standardization in the enterprise environment starts with the data tier of the back-end and the standard enterprise middle tier is being stabilized by standardization as it is accepted as the Spring Framework. In addition, with the advent of new devices in an increasingly rapid cycle, securing compatibility with web and mobile services has become an important competitive advantage for web service companies. However, companies are unable to secure competent technical personnel appropriate for the rapidly changing environment of the information generation, and the curriculum of educational universities does not reflect the demand of new competency-oriented curriculum. Therefore, in this study, in order to acquire competency-oriented skills required for such an enterprise system platform environment and to develop a curriculum, the system using Spring Data JPA in the Spring Framework environment was implemented through documenting for each analysis and design step. It aims to provide a reference model for the full stack competency-based curriculum and capstone design curriculum that can be applied immediately in the enterprise environment.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.135-135
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• 2017

The Gramene database (http://www.gramene.org) is a powerful online resource for agricultural researchers, plant breeders and educators that provides easy access to reference data, visualizations and analytical tools for conducting cross-species comparisons. Learn the benefits of using Gramene to enrich your lectures, accelerate your research goals, and respond to your organismal community needs. Gramene's genomes portal hosts browsers for 44 complete reference genomes, including crops and model organisms, each displaying functional annotations, gene-trees with orthologous and paralogous gene classification, and whole-genome alignments. SNP and structural diversity data, available for 11 species, are displayed in the context of gene annotation, protein domains and functional consequences on transcript structure (e.g., missense variant). Browsers from multiple species can be viewed simultaneously with links to community-driven organismal databases. Thus, while hosting the underlying data for comparative studies, the portal also provides unified access to diverse plant community resources, and the ability for communities to upload and display private data sets in multiple standard formats. Our BioMart data mining interface enable complex queries and bulk download of sequence, annotation, homology and variation data. Gramene's pathway portal, the Plant Reactome, hosts over 240 pathways curated in rice and inferred in 66 additional plant species by orthology projection. Users may compare pathways across species, query and visualize curated expression data from EMBL-EBI's Expression Atlas in the context of pathways, analyze genome-scale expression data, and conduct pathway enrichment analysis. Our integrated search database and modern user interface leverage these diverse annotations to facilitate finding genes through selecting auto-suggested filters with interactive views of the results.