• Spatial Information Research
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• v.22 no.5
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• pp.1-8
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• 2014

Globally, mobile, cloud computing or big data are the recent marketable key terms. These trend technologies or paradigm in the ICT (Information Communication Technology) fields exert large influence on the most application fields including geo-spatial applications. Among them, cloud computing, though the early stage in Korea now, plays a important role as a platform for other trend technologies uses. Especially, mobile cloud, an integrated platform with mobile device and cloud computing can be considered as a good solution to overcome well known limitations of mobile applications and to provide more information processing functionalities to mobile users. This work is a case study to design and implement the mobile application system for geo-spatial image filtering processing operated on mobile cloud platform built using OpenStack and various open sources. Filtering processing is carried out using R environment, recently being recognized as one of big data analysis technologies. This approach is expected to be an element linking geo-spatial information for new service model development and the geo-spatial analysis service development using R.

• Journal of Dental Rehabilitation and Applied Science
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• v.29 no.4
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• pp.407-417
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• 2013

The one of peri-implant soft tissue problems seen during the maintenance phase of implant therapy is an inadequate zone of keratinized tissue. Keratinized tissue plays a major role around teeth and dental implants, helping in maintaining and facilitating oral hygiene. A free gingival graft (FGG) is chosen to correct the soft tissue defects and provide optimal peri-implant health in order to increase the long-term prognosis of the implant reconstruction. However, the patient treated with FGG has pain and discomfort on donor site such as palate. It is also technically demanding, time consuming, and the color match of the tissue is often less than ideal. An apically positioned flap (APF) is selected for increasing the keratinized tissue simply while or after the second stage implant surgery. This case report shows successfully increasing the width of peri-implant kenratinized tissue through APF procedure on small site of dental implant instead of FGG.

• Clinical and Experimental Reproductive Medicine
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• v.38 no.3
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• pp.126-134
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• 2011

Preimplantation genetic diagnosis (PGD) is gradually widely used in prevention of gene diseases and chromosomal abnormalities. Much improvement has been achieved in biopsy technique and molecular diagnosis. Blastocyst biopsy can increase diagnostic accuracy and reduce allele dropout. It is cost-effective and currently plays an important role. Whole genome amplification permits subsequent individual detection of multiple gene loci and screening all 23 pairs of chromosomes. For PGD of chromosomal translocation, fluorescence $in-situ$ hybridization (FISH) is traditionally used, but with technical difficulty. Array comparative genomic hybridization (CGH) can detect translocation and 23 pairs of chromosomes that may replace FISH. Single nucleotide polymorphisms array with haplotyping can further distinguish between normal chromosomes and balanced translocation. PGD may shorten time to conceive and reduce miscarriage for patients with chromosomal translocation. PGD has a potential value for mitochondrial diseases. Preimplantation genetic haplotyping has been applied for unknown mutation sites of single gene disease. Preimplantation genetic screening (PGS) using limited FISH probes in the cleavage-stage embryo did not increase live birth rates for patients with advanced maternal age, unexplained recurrent abortions, and repeated implantation failure. Polar body and blastocyst biopsy may circumvent the problem of mosaicism. PGS using blastocyst biopsy and array CGH is encouraging and merit further studies. Cryopreservation of biopsied blastocysts instead of fresh transfer permits sufficient time for transportation and genetic analysis. Cryopreservation of embryos may avoid ovarian hyperstimulation syndrome and possible suboptimal endometrium.

• Journal of Ship and Ocean Technology
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• v.12 no.1
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• pp.16-27
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• 2008

The interaction between advancing ships and the waves generated by them plays important roles in wave resistances and ship motions. Wave breaking phenomena near the ship bow at different speeds are investigated both numerically and experimentally. Numerical simulations of free surface profiles near the fore bodies of ships are performed and visualized to grasp the general trend or the mechanism of wave breaking phenomena from moderate waves rather than concentrating on local chaotic irregularities as ship speeds increase. Navier-Stokes equations are differentiated based on the finite difference method. The Marker and Cell (MAC) Method and Marker-Density Method are employed, and they are compared for the description of free surface conditions associated with the governing equations. Extra effort has been directed toward the realization of extremely complex free surface conditions at wave breaking. For this purpose, the air-water interface is treated with marker density, which is used for two layer flows of fluids with different properties. Adaptation schemes and refinement of the numerical grid system are also used at local complex flows to improve the accuracy of the solutions. In addition to numerical simulations, various model tests are performed in a ship model towing tank. The results are compared with numerical calculations for verification and for realizing better, more efficient research performance. It is expected that the present research results regarding wave breaking and the geometry of the fore body of ship will facilitate better hull form design productivity at the preliminary ship design stage, especially in the case of small and fast ship design. Also, the obtained knowledge on the impact due to the interaction of breaking waves and an advancing hull surface is expected to be applicable to investigation of the ship bow slamming problem as a specific application.

• 한국균학회소식:학술대회논문집
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• 2016.05a
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• pp.41-41
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• 2016

Influenza viruses are RNA viruses that belong to the Orthomyxoviridae family, and those can be divided into three types; A, B, and C, which based on the differences of the inner nucleoproteins and genomic structures. All three genera differ in their genomic structure and nucleoprotein content, they are further classified into various serotypes based on the two surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA). These glycoproteins play crucial roles in viral infection and replication. Hemagglutinin mediates binding of virions to sialic acid receptors on the surfaces of target cells at the initial stage of infection. Neuraminidase cleaves the glycosidic bonds of sialic acids from the viral and cell surfaces to release the mature virions from infected cells, after viral replication. Because NA plays an important role in the viral life cycle, it is considered an attractive therapeutic target for the treatment of influenza. The methanolic extracts of Phellinus baumii and Phellinus igniarius exhibited significant activity in the neuraminidase inhibition assay. Polyphenolic compounds were isolated from the methanolic extracts. The structures of these compounds were determined to be hispidin, hypholomine B, inoscavin A, davallialactone, phelligridin D, phelligridin E, and phelligridin G by spectroscopic methods. Compounds inhibited the H1N1 neuraminidase activity in a dose-dependent manner with $IC_{50}$ values of 50.9, 22.9, 20.0, 14.2, 8.8, 8.1 and $8.0{\mu}M$, respectively. Moreover, these compounds showed anti-influenza activity in the viral cytopathic effect (CPE) reduction assay using MDCK cells. These results suggests that the polyphenols from P. baumii and P. igniarius are promising candidates for prevention and therapeutic strategies against viral infection.

• Journal of the Korean association of regional geographers
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• v.12 no.4
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• pp.437-448
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• 2006

Bare-topped thufur is called as frost scars, implying the rupturing stage of vegetated mounds, Field observations and measurements provide empirical information on the process and factors of thufur disintegration in Mt. Halla, Initial bare patches on mound apexes are scaled up by continuous removal of soil and vegetation, resulting in the formation of crater-like thufur, Frost action plays a primary role in thufur disintegration, In particular, pipkrake loosens soil particles within the bare patches and subsequently accelerates the degradation of vegetated mounds during periods with frequent diurnal freeze-thaw cycle and high soil moisture, Deflation also has an impact on thufur breakup in that the bare patches usually lack upper dark brown soil and are covered with granules, Withered shrubs such as Juniperus chinensis var. sargentii are frequently observed in frost scars and disrupted mounds, indicating that thufur disintegration has been probably influenced by global warming.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.11 no.1
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• pp.20-33
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• 1999

The evolution of deep-sea waves is driven by energy input from wind, nonlinear energy transfer between wave components, and dissipation through whitecaps. A comparative study was implemented by the use of two wave models in which only the computation methods of nonlinear wave-wave interactions are different from each other. It was reaffirmed that the nonlinear interaction plays a central role in such phenomena that occurred during the spectral growth of wind-seas as down-shift of the spectral peak frequency, overshoot, undershoot, and formation of self-similar spectrum. Specifically, the directional distribution at high frequencies develops into bimodal form, which is attributed to the nonlinear interactions. As saturation stage is reached, spectral density at high frequencies becomes proportional to negative 4 power to the frequency. Perturbations introduced into the spectrum quickly vanished through the actions of the self-similar mechanism. Thus, the nonlinear transfer has important contribution to the stability of numerical ocean wave models.

• Development and Reproduction
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• v.24 no.3
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• pp.187-196
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• 2020

The caspase10 encodes an initiating caspase that plays an important role in the maintaining the cellular homeostasis by regulating the steps involved in the immune response and cell death. We investigated the expression of caspase10 during the different developmental stages and in olive flounder tissues. Caspase10 increased in the late stage of the formation of immune tissue, and high expression was observed in the gills, kidney, skin, and spleen. The current study analyzed the expressional changes of caspase10 in olive flounder infected with viral hemorrhagic septicemia virus (VHSV). One of the major causes of mass mortality, VHSV infection in olive flounder attributes to significant expression of caspase10 in the gills, spleen, skin, and kidneys. The results indicate a close association of caspase10 expression with the immune response to VHSV infection in olive flounder. The observations could form the basis data for exploration of other fish immune system.

• Journal of Korean Society for Geospatial Information Science
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• v.10 no.1 s.19
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• pp.27-35
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• 2002

The dam made reservoir, a major means to overcome the problems caused by water resource's uneven supply by time and space, plays an important role, particularly, of water supply. The role of water supply will get more important, considering the usage of water resource becomes more intensive. Therefore, it is continuously required to construct new dams securing water supply and to study on effective operation plans of the dam. The size of reservoir needs to be measured according to possible supply estimation in the pre-design stage. The depth of water, at this point, should be taken. Among many ways of sounding, echo sounding has been frequently used recently. This study, therefore, presents a new way of sounding that takes less time with stronger accuracy, uniting GPS and echo sounder to apply a means of obtaining three dimensional position data. This enables the designer to escape from the conventional way of sounding in the estimation of reservoir to design and redesign a new dam.

• The Transactions of the Korea Information Processing Society
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• v.3 no.3
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• pp.449-459
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• 1996

The main goal of this paper is to introduce a novel definition for fuzzy mathematical morphology and a neural network implementation. The generalized- mean operator plays the key role for the definition. Such definition is well suited for neural network implementation. The first stage of the shared-weight neural network has adequate architecture to perform morphological operation. The shared- weight network performs classification based on the features extracted with the fuzzy morphological operation defined in this paper. Therefore, the parameters for the fuzzy definition can be optimized using neural network learning paradigm. Learning rules for the structuring elements, degree of membership, and weighting factors are precisely described. In application to handwritten digit recognition problem, the fuzzy morphological shared-weight neural network produced the results which are comparable to the state-of art for this problem.