• 미생물학회지
• /
• 제27권4호
• /
• pp.430-435
• /
• 1989

Dextranase와 glucose←oxidase의 향치아우식 인자로서의 효괴와 dentifrice 앙분으로서의 이용 가능성융,경토하였다. W Water-insoluble glucan에 의한 plaque의 형성은 dextranase와 glucose-oxida앤플 사용함으호써 억제할 수 9.]였다. D Dextranase의 경우 낮은 농도에서도 plaque의 형생억저l와 분해에 매우 효과적이였다. Glucose-oxidase의 경우 얄균작용 에 의해 생균수를 줄임으로써 plaque의 형성억제에는 효과적이었으나 분해작용은 미약하였다. Dentifrice의 각 성분에 대한 compatibility test 를 통해 효소의 안쟁화를 위한 Mode] Dentifrice 플 구생하였고. Model Dentifrice 에서의 activity 변 화플 관창한 결과 안정성이 오랫동안 유지될을 확인할 수 있었다.

• 한국안전학회지
• /
• 제26권5호
• /
• pp.1-6
• /
• 2011

Flame extinction and the chemistry of stoichiometric methane/air mixture were investigated numerically in the PSR(perfectly stirred reactor). For the study, PSR code was modified to be possible to unsteady calculation, and the sinusoidal fluctuation was subjected to the residence time. In the region of residence time far from the extinction limit, combustion mode was strongly dependent on the frequency. The low frequency excitation provided the quasi-steady behavior on the temperature and the concentrations of related species, but small variation of temperature was observed under high frequency. In the region of residence time near the extinction limit, the mixture subjected above 1 KHz was still reacting even though extinction had to be occurred under quasi-steady concept. The attenuation of extinction limit resulted from that chemical time was comparable to the flow time. The mean mole fractions of both NO and CO were almost same regardless of imposed frequency. However, the average mole fraction of $C_2H_2$ was decreased as increasing frequency, which implies that soot yield might be reduced at the higher frequency of flow excitation. The result provides the basic concept for flame stabilization, and it will be used to design a mild combustor.

• 전기학회논문지
• /
• 제57권4호
• /
• pp.567-575
• /
• 2008

Transient security assessment(TSA) is becoming an essential requirement not only for security monitoring but also for stabilizing control of power systems under new electricity environments. It has already been pointed out that fast transient stability study is an important part for monitoring and controlling system security. In this paper, we discuss an energy function method for stabilizing control of transiently unstable systems by introducing generator tripping system to enhance the transient stability of power systems. The stabilization with less tripped power can be obtained by tripping the generators faster than out-of-synchronism relay. Fast transient stability assessment based on the state estimation and direct transient energy function method is an important part of the stabilizing scheme. It is possible to stabilize the transiently unstable system by tripping less generators before the action of out-of-synchronism relay, especially when a group of generator are going to be out-of-synchronism. Moreover, the amount of generator output needed for tripping can be decided by Transient Energy Function(TEF) method. The main contribution of this paper is on the stabilizing scheme which can be running in the Wide Area Control System.

• 해양환경안전학회지
• /
• 제27권2호
• /
• pp.211-218
• /
• 2021

본 연구는 종방향과 횡방향에서 규칙파가 외란으로 입사하는 선박의 종동요 및 횡동요를 억제하는 문제를 다룬다. 선박의 안전 운항을 위해서 파랑 중 선박의 종동요 및 횡동요를 안정화시키는 것은 필수적인 과제로 여겨진다. 종동요 및 횡동요 거동에서 중요한 특징 중에 하나는 공진인데, 이 현상은 특정한 조건에서 예상치 못한 큰 응답을 초래한다. 종동요와 횡동요는 두 운동이 상호 결합되어 있고 복원항이 강한 비선형을 갖고 있음으로 계의 파라미터에 따라 다양한 동적 거동을 보이는 것이 중요한 특징인데, 특히 종동요에서 이 특성이 두드러지게 나타난다. 무엇보다, 선박의 조종성능 및 안전을 위해 선박의 종동요 가속도 응답을 완전히 억제하는 것은 상당히 도전적인 과제이다. 이 연구에서는 준 슬라이딩 모드 제어 기법을 이용하여 종동요와 횡동요를 줄임으로 파랑 중의 선박을 안정적인 직립 상태로 유지시키고, 아울러 채터링을 감소시키는 목적을 달성하였다. 리아프노프 이론으로 준 슬라이딩 모드 제어의 안정성을 판명하였고, 수치 시뮬레이션으로 제어 방식의 유효성을 증명하였다. 제시한 기법으로 종동요 및 횡동요 응답의 수렴 및 채터링 감소라는 두 가지 목표가 효과적으로 달성되었다.

• Archives of Pharmacal Research
• /
• 제22권5호
• /
• pp.485-490
• /
• 1999

The mechanism of action of fish oil (FO), currently used in different chronic inflammatory conditions such as rheumatoid arthritis (RA), is not completely understood, although it is thought that it could alter the metabolism of endogenous autacoids. In addition, we hypothesized that the known capability of fatty acids (FA) of stabilizing serum albumin and perhaps other proteins, may be of pharmacological relevance considering that it is shared by other anti-rheumatic agents (e.g. nonsteroidal antiinflammatory drugs). Thus, we studied the effect of oral administration of FO and corn oil (CO), a vegetable oil with a different composition, on the stability of rat serum proteins, evaluated buy a classical in vitro method based on heat-induced protein denaturation. FO, and, to a lower extent, CO inhibited heat-induced denaturation of rat serum (RS): based on the inhibitory activity (EC50) of the major fatty acids against heat-induced denaturation of RS in vitro, it was possible to speculate the in vivo effects of palmitic acid (C16:0) and eicosapentaenoic acid (EPA, C20:5, n-3) may be more relevant than that of linolenic acid (C18:2). To better investigate this phenomenon, we extracted albumin from the serum of animals treated or not with FO with a one-step affinity chromatography technique, obtaining high purity rat serum albumin preparations (RSA-CTRL and RSA-FO), as judged by SDS-PAGE with Coomassie blue staining. When these RSA preparations were heated at $70^{\circ}C$ for 30 min, it was noted that RSA-FO was much more stable than RSA-CTRL, presumably due to higher number of long chain fatty acids (FA) such as palmitic acid or EPA. In conclusion, we provided evidences that oral administration of FO in the rat stabilizes serum albumin, due to an increase in the number of protein bound long chain fatty acids (e.g. palitic acid and EPA). We speculate that the stabilization of serum albumin and perhaps other proteins could prevent changes of antigenicity due to protein denaturation and glycosylation, which may trigger pathological autoimmune responses, suggesting that this action may be involved in the mode of action of FO in RA and other chronic inflammatory diseases.

• 대한약리학회지
• /
• 제30권1호
• /
• pp.67-73
• /
• 1994

Na-Ca 교환은 calcium 이온을, 세포 내외의 Na 이온 농도차에 의해서 형성되는 원동력의 방향에 따라, 세포내로(역방향 Na-Ca 교환), 혹은 세포밖으로(정방향 Na-Ca 교환) 이동시킨다. 그러므로 Na-Ca 교환은 심근 수축 운동의 조절 기전의 하나로 받아 들여지고 있다. 그러나, 세포내의 Na 이온 농도는 항상 세포외의 농도보다 낮으므로, 역방향 Na-Ca 교환의 존재와 아울러 이의 심근 수축에 있어서의 역할 가능성에 대해 많은 연구자들이 회의를 가지고 있는 것이 사실이다. 그러므로 본 연구는 흰쥐의 좌심방을 이용하여, 역방향 Na-Ca 교환의 존재 여부와 그 역할의 존재 가능성을 추구하여 보고자 하였다. 흰쥐의 좌심방은 전기장 자극(0.5msec, supramaximal voltage)으로 수축을 유발하고, 자극 빈도를 안정시 4Hz에서 0.4, 1, 8Hz로 변동시킬때 그 수축 장력에서 특징적인 역 사다리 효과(negative staircase effect)가 나타내었으나, 이때 $^{45}Ca$ 섭취는 저빈도로 갈수록, 또한 고빈도로 갈수록 증가되는 이원적인 증가를 나타내었다 자극 빈도를 4Hz 에서 0.4Hz로 변동시에는 수축 장력이 특징적인 삼단계 변환, 즉 급격히 증가하는 첫단계에 이어 급격하게 감소하는 이단계와 안정되어지는 삼단계로 나타났다. $^{45}Ca$ 섭취도 장력 변동과 같은 양상으로 처음 30초 동안에 현저하게 증가한 후 감소되었다. Na-Ca 억제 약물인 benzamil은 $10^{-5}M$에서부터 $3{\times}10^{-4}M$까지 용량에 비례하여 특히 초기의 장력증가를 봉쇄하였다. Bay K-8644$(3{\times}10^{-5}M)$ 처치는 자극 빈도 감소에 따른 수축력 증가를 현저하게 항진시켰으며, benzamil처치는 이때에도 억압을 나타내었다. Verapamil $3{\times}10^{-5}M$ 전처치시에는 4Hz 자극시의 수축 운동은 완전히 소실시켰으나, 0.4 혹은 1 Hz로 바꿈에 따라 수축 운동이 재현되었다. 이때 $^{45}Ca$ 섭취는 verapamil을 전처치하지 않은 경우보다 현저하게 항진되었다. 이상의 결과로 보아, 흰쥐의 좌심방에서 자극 빈도 감소후에는, 먼저 역방향 Na-Ca 교환에 의해 calcium이온이 세포내로 유입되어 수축운동의 항진이 유발되고, 이어 Na-Ca 교환이 정방향으로 변환되어 calcium이온을 세포밖으로 유출시킴에 따라 수축 운동이 감소된다고 생각한다.

• 대한기계학회논문집A
• /
• 제40권4호
• /
• pp.343-352
• /
• 2016

멀티로터 비행체는 여러 개의 로터로 이루어진 무인 비행로봇으로서, 로터의 개수에 따라서 트라이로터, 쿼드로터, 헥사로터, 옥토로터 등으로 나누어 진다. 멀티로터는 수직이착륙 및 정지비행과 같은 높은 기동성으로 인하여 다른 무인 비행로봇에 비하여 험준한 산학지역 및 건물이 밀집되어 있는 도심과 같은 지역의 정찰 및 감시 등 여러 응용분야에 유용하게 활용될 수 있다. 하지만, 멀티로터는 불확실한 외부 환경 및 외란의 영향에 쉽게 노출될 수 있어 강건한 자세 및 비행제어 기법의 적용을 필요로 한다. 본 논문에서는 강인제어기법 중 하나인 슬라이딩 모드제어기를 설계 및 임베디드 알고리듬을 구현을 통하여 실시간 실내 비행실험을 위한 시스템을 구성하고, 실시간 위치제어 및 자세 안정화에 대한 실내 비행실험을 수행하였다. 특히, 불확실한 외부환경에 대한 강건한 비행특성을 검증하기 위하여 외란을 삽입하여 비행시험을 통해 성능을 검증하였다.

• 전력전자학회논문지
• /
• 제19권5호
• /
• pp.399-406
• /
• 2014

This study investigates the structure and operation of the ITER VS converter and proposes a sequence control method for six series-connected VS converters to reduce reactive power. The operation and the proposed sequence control method are verified through RTDS simulation. The ITER VS converter must supply voltage/current to the superconducting magnets for plasma current vertical stabilization, and the four-quadrant operation must proceed without a zero-current discontinuous section. The operation mode of the VS converter is separated into a 12- and 6-pulse circulating current and transition modes according to the size of the load current. The output voltage of the unit VS converter is limited because of the rated voltage; however, the superconducting coil must increase the operating output voltage. Thus, the VS converter must be connected in a 6-series to provide the required operating output voltage. The output voltage of the VS converters is controlled continuously; however, reactive power is limited within a minimized value of the grid. In this study, the unit converter is compared with converters connected in a 6-series to determine a suitable sequence control method. The output voltage is the same in all cases, but the maximum reactive power is reduced from 100% to 73%. This sequence control method is verified through RTDS simulation.

• 한국안전학회지
• /
• 제27권1호
• /
• pp.20-25
• /
• 2012

The purpose of the study is to assess the extinguishing concentration of inert gases in engine nacelle fire. The experiment was performed with a two dimensional rectangular bluff body stabilized flames, where the fuel was ejected to counter flow and co-flow against an oxidizer stream. Two inert gases, $CO_2$ and $N_2$, were used for extinguishing agent in the oxidizer and methane was used for fuel. The main experimental parameters were the direction of injecting fuel, the kinds of agent and the velocity ratio between air and fuel streams, which controlled the mixing characteristic near bluff body and the strength of recirculation zone in the downstream. The result shows the flame structure and the mode were strongly dependent with fuel/air ratio and the fuel jet direction. For both flow configurations, the extinguishing concentration of $CO_2$ was smaller than the $N_2$ because of the large heat capacity of $CO_2$. However, the concentration of inert gasesat blowout was much smaller than those in the cup burner and coflow jet diffusion flames, which implies that the extinction mechanism of bluff body stabilized flames was mainly due to the aerodynamic aspect. Compared to co-flow fuel injection, the extinguishing concentration of inert gases under counter flow configuration was lower. The effect of direction might result from the mixing characteristic and strength of recirculation zonearound a bluff body. More details should be investigated for the characteristic of recirculation zone in the wake of bluff body using the LES(Large Eddy Simulation).

• Journal of Power Electronics
• /
• 제11권6호
• /
• pp.870-879
• /
• 2011

Regulated peak power tracking (RPPT) systems such as the series structure and the series-parallel structures are commonly used in satellite space power systems. However, these structures process the solar array power or the battery power to the load through two cascaded regulators during one orbit cycle, which reduces the energy transfer efficiency. Also the battery charging time is increased due to placement of converter between the battery and the solar array. In this paper a parallel structure has been proposed which can improve the energy transfer efficiency and the battery charging time for satellite space power RPPT systems. An analogue controller is used to control all of the required functions, such as load voltage regulation and solar array stabilization with maximum power point tracking (MPPT). In order to compare the system efficiency and the battery charging efficiency of the proposed structure with those of a series (conventional) structure and a simplified series-parallel structure, simulations are performed and the results are analyzed using a loss analysis model. The proposed structure charges the battery more quickly when compared to the other two structures. Also the efficiency of the proposed structure has been improved under different modes of solar array operation when compared with the other two structures. To verify the system, experiments are carried out under different modes of solar array operation, including PPT charge, battery discharge, and eclipse and trickle charge.