• Title/Summary/Keyword: Spread through air spaces

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Poor Prognosis of Grade 2 Spread Through Air Spaces in Neuroendocrine Tumors

  • Chae, Mincheol;Cho, Sukki;Chung, Jin-Haeng;Yum, Sungwon;Kim, Kwhanmien;Jheon, Sanghoon
    • Journal of Chest Surgery
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    • v.55 no.2
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    • pp.101-107
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    • 2022
  • Background: Spread through air spaces (STAS) has recently emerged as a prognostic factor in lung adenocarcinoma, but little is known about the association of STAS and its grade with recurrence in neuroendocrine tumors (NETs). This study investigated the prognostic effect of STAS grade in NETs after curative resection. Methods: Seventy-seven patients were retrospectively reviewed, including 9 with typical carcinoid (TC), 6 with atypical carcinoid (AC), 26 with large cell neuroendocrine carcinoma (LCNEC), and 36 with small cell carcinoma (SCC). STAS was defined as the presence of floating tumor cells within air spaces in the lung parenchyma beyond the edge of the main tumor. STAS was classified as grade 1 or 2 depending on whether it was found within or beyond one ×10 objective lens field away from the main tumor margin, respectively. Results: Fifty-four patients (70%) had STAS, including 22% with TC, 50% with AC, 69% with LCNEC, and 86% with SCC. Patients with STAS had more nodal metastasis, lymphatic and vascular invasion, tumor necrosis, and tumor subtypes other than TC. Among STAS cases, grade 2 STAS was present in 33% of AC, 78% of LCNEC, and 87% of SCC. The 5-year recurrence-free survival (RFS) rate was 81%, 63%, and 35% in patients with no STAS, grade 1, and grade 2 STAS, respectively. Multivariate analysis found that grade 2 STAS was an independent negative prognostic factor for RFS. Conclusion: Although STAS itself was not associated with a poor prognosis, grade 2 STAS was an independent negative prognostic factor for RFS.

A Study on Characteristics of Indoor space and Food related of Japanese restaurant as successful model for globalizing Korean restaurants - Japanese restaurants in Hong Kong - (한식당 세계화를 위한 성공모델로서의 일식당 실내공간과 음식관련요소의 특성 연구 - 홍콩 소재 일식당 대상 -)

  • Lee, Ji-Hyun;Oh, Hye-Kung
    • Korean Institute of Interior Design Journal
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    • v.18 no.1
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    • pp.54-63
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    • 2009
  • The present study is a basic research for promoting the globalization of Korean food, aiming to analyze Japanese restaurants in Hong Kong, an international city successful in globalization, focused on their spatial characteristics and food related characteristics and to use the results as basic materials. The results of this study are as follows. As to the characteristics of indoor spaces and food of Japanese restaurants in Hong Kong, first, the locations of Japanese restaurants were mostly easily accessible luxury hotels, office buildings or shopping malls. They displayed Japanese styles well and used conspicuous signs. Their trade names were given after traditional place names, food names, greetings, etc. Second, the spaces of Japanese restaurants expressed contemporary and, at the same time, traditional styles moderately and elegantly by applying emphatic articles such as traditional furniture, tools and folk paintings to contemporary spaces with traditional air, and by doing so, they showed various possibilities. Third, as to the characteristics of food culture, menus were diversified from traditional menus such as kaiseki to everyday menus such as vinegared rice, ramen, skewered roast meat and fusion dish, and at the same time, differentiated by concept. In addition, some restaurants succeeded in globalization and modernization with chains throughout the world. Furthermore, while table setting, food dishing and tableware image were harmonized with the concept of the restaurant space, if tradition needed to be displayed it was used at a minimum, showing the Japanese aesthetic sense through the restaurant space and food. In globalizing Korean restaurants based on the results of this study, we need to link trade name, facade, sign, menu and space with served food, and to plan a consistent story so that Korean culture and images are expressed. In addition, if a manual is made by benchmarking the Japanese government's support policies and relevant businesses' efforts and ideas and provided to Korean restaurants, it will be helpful for Korean restaurants, which spread Korean food culture, to be more competitive and graceful.

An Experimental Study on the Analyze the Pressure Difference in case of Fire in Vertical Space of High-Rise Buildings (고층건축물 수직공간의 화재 시 압력차 분석을 위한 실험적 연구)

  • Huh, Yerim;Kim, HyeWon;Jin, SeungHyeon;Kwon, YoungJin
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2020.06a
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    • pp.111-112
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    • 2020
  • As buildings in South Korea become more skyscrapers, the risk of fire is also emerging. Thus, regulations, regulations, and guidelines are being improved to prevent the spread of smoke in the event of a fire in high-rise buildings, but research on smoke flow and pressure distribution in vertical spaces is insufficient. Therefore, in this study, the temperature of each floor in the vertical space according to the size of the fire is measured through the miniature model experiment, and the pressure difference is calculated to establish the basic data for the improvement of the performance of domestic air supply facilities in the future. Thus, a scale model of one-sixth the size of the actual building was produced to measure the temperature, and the pressure difference was derived by substituting the value for the expression. The pressure difference varies depending on the size of the cause of the fire, and it is believed that the differential pressure and conditions of the building should be taken into account before calculating the supply volume for the analysis of the pressure difference according to the size of the cause of the fire in the event of fire.

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Analysis of Cold Air Flow Characteristics according to Urban Spatial Types to Construct a Wind Road - Focused on Urban Area of Changwon - (바람길 조성을 위한 도시공간유형별 찬공기 유동 특성 분석 - 창원시 도시지역을 중심으로 -)

  • LEE, Su-Ah;SONG, Bong-Geun;PARK, Kyung-Hun
    • Journal of the Korean Association of Geographic Information Studies
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    • v.25 no.2
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    • pp.30-47
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    • 2022
  • This study analyzed the characteristics of cold air flow according to spatial types in urban areas of Changwon-si, Gyeongsangnam-do. The spatial types were classified by cluster analysis considering the land use map, building information, and topographic characteristics produced on the Changwon biotope map. The amount of cold air and wind speed were derived by KLAM_21 modeling. As a result, spatial types were classified into a total of 14 types considering the density and height of buildings, land use types, and topographic characteristics. Cold air flow was found to generate cold air in the valley of the forest area outside urban area, move through roads and open spaces, and accumulate in the low-lying national industrial complex, and then spread cold air throughout the urban areas. There was a lot of cold air flow in the tall building area, and the cold air accumulation was less in the slope and ridge areas. The results of this study were able to understand the characteristics of cold air flow according to building density, land use type, and topography, which will be usefully used as basic data for urban wind road construction to mitigate climate and improve air quality in urban areas.

Evaluation of Ventilation Performance of a Residential Unit for Different Sampling Points through Actual Field Tests (실증실험을 통한 측정 위치에 따른 주거공간 환기성능 평가)

  • Kwag, Byung Chang;Lee, Soo Man;Kim, Gil Tae;Kim, Jong Yeob
    • Land and Housing Review
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    • v.13 no.3
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    • pp.93-106
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    • 2022
  • Ventilation plays an important role in controlling indoor air quality. Due to the recent spread of infectious diseases such as COVID-19 and with people spending more time indoors, there's been increased attention on the importance of ventilation performance. In many countries, ventilation is regulated by airflow rates and the number of air changes per hour (ACH). However, airflow rates and ACH alone do not provide an accurate account of actual indoor pollutant removal and ventilation uniformity in a space. This study looked into the ventilation performance of an actual residential unit using several sampling points instead of basing it off of airflow and air change rates. Literature review was used to derive relevant influencing factors and the tracer gas dilution method was used for the field test. The study measured air velocity, age of air, and ventilation efficiency at several locations and compared them to the average value at the center of the test space to determine the differences in ventilation performance at the selected measurement points. The study showed that different sampling locations resulted in different ventilation values. Findings of this study will be used to develop an experimental procedure for evaluating indoor ventilation performance of actual residential spaces.