• Title/Summary/Keyword: Spray formulation

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A Test of Antifungal Spray Formulation Containing Nanosized Silica-Silver Particles Prepared by Using Gamma Irradiation for Practical Use to Control Indoor Fungi (감마선 조사에 의해 제조된 나노-실리카은 유무기복합 입자를 포함한 항진균성 스프레이 제제의 생활환경 저해균에 대한 실용성 검토)

  • Kim, Seong-Ho;Park, Hae-Jin;Kim, Hwa-Jung;Park, Hae-Jun
    • Journal of Radiation Industry
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    • v.2 no.3
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    • pp.149-154
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    • 2008
  • The present study described an antimicrobial spray composition comprising nanosized silica-silver particles, in which nano-silver is bound to silica molecules and a water-soluble polymer, the nanosized silica-silver particles prepared by irradiating a solution comprising a silver salt, silicate and the water-soluble polymer with radiation rays. According to a surfactant addition, the compositions were not turbid and were colorless. Also samples (cotton fabrics and wallpaper) were treated with the compositions also did not cause any stains even after drying under sunshine and at $80^{\circ}C$. Our results suggested that the spray formulation product was of practical use to control indoor fungi.

Effect of Molecular Weights and Mixture Ratios of Polyvinylpyrrolidone on the Bioavailability of Ipriflavone Solid Dispersion (이프리플라본 고체분산체의 생체이용률에 미치는 폴리비닐피롤리돈의 분자량 및 혼합비율의 영향)

  • Jeong, Je-Kyo;Khang, Gil-Son;Rhee, John-M.;Shin, Ho-Chul;Lee, Hai-Bang
    • Journal of Pharmaceutical Investigation
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    • v.30 no.4
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    • pp.235-239
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    • 2000
  • Ipriflavone (3-phenyl-7-isopropoxy-4H-1-benzopyran-4-one, IP) is a well-known antiosteoporotic drug with poor bioavailability. In the previous study, we reported that the IP formulation prepared by spray-drying method with polyvinylpyrrolidone (PVP) (SIP) was very effective in improving the bioavailability of IP. In this study, we examined the effects of molecular weight and mixture ratios of PVP to IP on the systemic absorption of IP following oral administration of SIP at a dose of 50 mg/kg to rats. In the effect of molecular weight, the Cmax of spray-dried IP with PVP K30 (SIP-K30) was significantly higher than those of spray-dried IP with PVP 360 (SIP-360), spray-dried IP with PVP K90 (SIP-K90), and spray-dried IP with PVP K17 (SIP-K17) (p<0.05). The AUC of SIP-K30 was about 2, 3, and 5.5 times higher than those of SIP-360, SIP-K90, and SIP-K17, respectively. The AUC value of SIP-K30 was significantly greater than those of SIP-K17 and SIP-K90 (p<0.05) except for SIP-360. In the ratio of PVP K30 to drug, the $C_{max}$ and the AUC value of 3 : 7 IP-PVP solid dispersion were similar to those of 5 : 5 IP-PVP and significantly higher than those of the other solid dispersions (p<0.05). It was concluded that the spray-dried IP with PVP K30 at the ratio of 3:7 (w/w) was the best formulation for improving the bioavailability of IP.

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Study on Vaporization and Combustion of Spray in High Pressure Environment (고압에서의 분무의 증발 및 연소 현상에 관한 연구)

  • Wang, Tae-Joong;Baek, Seung-Wook
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.27 no.9
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    • pp.1273-1281
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    • 2003
  • The present study is mainly motivated to investigate the vaporization, auto-ignition, and combustion of liquid fuel spray injected into high pressure environment. The unsteady, multi-dimensional models were used for realistic simulation of spray as well as prediction of accurate ignition delay time. The Separated Flow (SF) model which considers the finite rate of transport between liquid and gas phases was employed to represent the interactions between spray and gas field. Among the SF models, the Discrete Droplet Model (DDM) which simulates the spray using finite number of representative samples of discrete droplets was adopted. The Eulerian-Lagrangian formulation was used to analyze the two-phase interactions. In order to predict an evaporation rate of droplet in high pressure environment, the high pressure vaporization model was applied using thermodynamic equilibrium and phase equilibrium at droplet surface. The high pressure effect as well as high temperature effect was considered in the calculation of liquid and gas properties. In case of vaporization, an interaction between droplets was studied through the simulation of spray. The interaction is shown up differently whether the ambient gas field is at normal pressure or high pressure. Also, the characteristics of spray behavior in high pressure environment were investigated through the comparison with normal ambient pressure case. In both cases, the spray behaviors are simulated through the distributions of temperature and reaction rate in gas field.

Study on Spray Vaporization and Combustion in High Pressure Environment (고압에서의 분무의 증발 및 연소 현상에 관한 연구)

  • Wang, Tae-Joong;Baek, Seung-Wook
    • 한국연소학회:학술대회논문집
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    • 2002.11a
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    • pp.193-207
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    • 2002
  • The present study is mainly motivated to investigate the vaporization, autoignition, and combustion of liquid fuel spray injected into high pressure environment. In order to represent these phenomena realistically, discrete droplet model (DDM) which simulates the spray using finite number of representative droplets was adopted for detailed consideration of the finite rate of uansport between liquid and gas phases. The Eulerian-Lagrangian formulation was used to analyze the two-phase interactions. The high pressure vaporization model was applied using the thermodynamic and phase equilibrium at droplet surface. The high pressure effect as well as high temperature effect was considered in the calculation of liquid and gas properties. The characteristics of spray in high pressure environment were explained by comparison with normal pressure case.

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A numerical analysis and experimental study on the prediction of spray characteristics (분무특성 예측을 위한 이론적 접근과 실험적 연구)

  • Yoon, S.J.;Cho, D.J.
    • Journal of ILASS-Korea
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    • v.3 no.2
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    • pp.1-13
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    • 1998
  • A theoretical and experimental study was carried out to predict the drop size distribution of the pressure swirl atomizer. Various analytical methods using the Kelvin-Helmholtz instability theory were tried to examine the wave growth on cylindrical liquid sheets. Cylinderical liquid sheets were extended to the case with the conical sheets. Perturbations due to tangential motion as well as longitudinal one were taken into account. And it was assumed that the breakup occurs when amplitude ratio exceeds exp(12), drop sizes were predicted only by theoretical approach. Drop size distribution was obtained by using maximum entropy formalism. Seven constraints in the form of the definition of mean diameter were used in this formulation in order to avoid the difficulties of estimating source terms. In this study $D_{10}$ only was introduced into the formulation as a constraint. The predicted drop size and drop size distribution agreed well with the measured data.

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Preparation and Characterization of Muscovite Mica/UV Coating Materials for Steel

  • Cheong, In-Woo;Kim, Hyeon-Seok;Hwang, Dong-Seop;Yoo, Hye-Jin;Kim, Jin-Tae;Lee, Jae-Ryung
    • Corrosion Science and Technology
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    • v.9 no.6
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    • pp.265-269
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    • 2010
  • This paper describes the exfoliation and surface modification of muscovite mica for UV coating formulation. For the exfoliation of the mica, hydrothermal process was used in the presence of lithium nitrate ($LiNO_3$). After the cation exchange with $Li^+$ ions, the surface of the mica was modified with several amphiphilic substances to increase compatibility and storage stability in UV coating formulation. Such a hydrophobic surface modification affected colloidal stability as well as dispersibility of the exfoliated mica in UV coating solution. Anticorrosive property of mica/UV coated steel plates was tested by salt spray test (SST) and compared with sodium montmorillonite ($Na^+$-MMT)/UV coated steel plates.

Dynamic Analysis of Metal Transfer using VOF Method in GMAW (I) - Globular and Spray Transfer Modes (VOF 방법을 이용한 GMA 용접의 금속 이행에 관한 동적 해석 (I) - 입상 용적과 스프레이 이행 모드의 해석 -)

  • 최상균;유중돈;김용석
    • Journal of Welding and Joining
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    • v.15 no.3
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    • pp.36-46
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    • 1997
  • Dynamics of molten drop detachment in the Gas Metal Arc (GMA) welding is investigated using the Volume of Fluid(VOF) method. The electromagnetic effects are included in the formulation of the VOF method which has been widely used to analyze the dynamics of the fluid having a free surface. The molten drop geometry, pressure and velocity profiles within the drop are calculated numerically in the cases of globular and spray transfer modes. It appears that the velocity and current distribution affect metal detachment. It is found that the taper is formed and maintained during the spray transfer by the electromagnetic force. Predicted results show reasonably good agreement with the available experimental data which validates the application of the VOF method to metal transfer analysis.

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Formulation and Magnetic properties of Sr-ferrite powders by Modified spray co-roasting (단순화된 분무열분해법을 이용한 Sr-ferrite 제조와 자기특성)

  • 김효준;조태식;남효덕;양충진
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1998.06a
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    • pp.49-52
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    • 1998
  • Preparation of hexagonal strontium-ferrite by modified spray co-roasting(MSC:H) which is expected to shorkn the length of the process and to elevate the magnetic properties of hard ferrite was studied. We prapared $Fe_2O_3/SrCO_3$ mixture powders by MSCR after stirring ionized $FeCI_2$ in distilled water with solid state $SrCO_3$. And then calcined the mixture powders up to $1150^{\circ}C$ for Sr-ferrite powders It is possible to prepare hexaferrite powders with high saturation magnetization (Ms > 69 emu/g) , coercivity (Hc > 4000 Oe) The nlagnetic values of saturation magnetization iire higher than those achieved by the conventional technique.

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Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham

  • Kim, Seung Wook;Garcia, Coralia V.;Lee, Bom Nae;Kwon, Ho Jeong;Kim, Jun Tae
    • Food Science of Animal Resources
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    • v.37 no.6
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    • pp.889-897
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    • 2017
  • In this study, a nanoemulsion formulation for encapsulating turmeric extract was developed and its physicochemical characteristics including particle diameter, zeta potential, polydispersity index, and stability were determined. The turmeric nanoemulsion (TE-NE) droplets exhibited small diameter (165 nm), low PDI (0.17), and high zeta potential (-31.80 mV), all desirable characteristics in nanoemulsions, as well as stability in a wide range of pH. The TE-NE was spray-dried as a means to allow its incorporation into food products and reduce potential transport and storage costs. The resulting powder exhibited a pale yellowish appearance and had a curcuminoids content of 0.39 mg/g. The spray-dried TE-NE powder was incorporated into minced pork to make canned ham, and the sensory characteristics of the ham were evaluated. As a result, the canned ham incorporating TE-NE powder received the same overall acceptability score as the control, and only exhibited slight yellowing. By contrast, ham incorporating turmeric extract exhibited substantial yellowing, and its appearance was considered less acceptable by the panelists. Therefore, the TE-NE formulation could be incorporated into canned ham and other meat products without substantially affecting their sensory qualities.

Enhancement of Biological Control of Botrytis cinerea on Cucumber by Foliar Sprays and Bed Potting Mixes of Trichoderma harzianum YC459 and Its Application on Tomato in the Greenhouse

  • Lee Sun-Kug;Sohn Hwang-Bae;Kim Geun-Gon;Chung Young-Ryun
    • The Plant Pathology Journal
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    • v.22 no.3
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    • pp.283-288
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    • 2006
  • Trichoderma harzianum YC459 (Th 459), isolated from sawdust compost, was effective in controlling cucumber and tomato gray mold caused by Botrytis cinerea under controlled and plastic film tunnel conditions. A water suspension of the wettable powder formulation of Th 459 significantly $(P\leq0.05)$ reduced the severity of cucumber gray mold by foliar spraying at all tested concentrations from $10^5\;to\;10^8$ colony forming unit (cfu)/ml in repeated experiments. The control efficacy was maintained at least seven days with the average control value of 70% in cucumber pot tests. Mixing one to eight grams of the granular formulation ($10^8cfu/g$ dry weight) of Th 459 into one liter nursery potting mix at seeding also significantly $(P\leq0.05)$ reduced the severity of cucumber gray mold by suppression of lesion formation three weeks after treatment. Application of mixing granular formulation at seeding in combination with foliar spraying during cultivation provided a more significant reduction $(P\leq0.05)$ of cucumber gray mold than granule mixing or leaf spray alone. The foliar spraying of the formulated wettable powder of Th 459 significantly $(P\leq0.05)$ reduced the infection of tomato fruits by B. cinerea as effective as the chemical fungicide, dichlofluanid, in three plastic film tunnel experiment trials. It is suggested that effective control of gray mold of cucumber and tomato can be provided by both treatment of Th 459 into potting mix and foliar spray through induction of systemic resistance and direct inhibition of the pathogen.