• 한국미생물학회:학술대회논문집
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• 한국미생물학회 2002년도 추계학술대회
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• pp.94-99
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• 2002

The oceans cover about $71\%$ of the Earth's crust and contain nearly 300,000 described species. Free-living bacteria in the sea and symbiotic bacteria of marine invertebrates are proving to be valuable sources of useful bioactive compounds. Marine sponges, in particular, which contain diverse communities of bacteria, produce many classes of compounds that are unique to the marine environment. Uncultured microorganisms are commonly believed to represent $99.9\%$ of the whole microbial community. They have been investigated for the possibility of isolating and over-expressing genes in viable microorganisms. Strict symbiotic species that have been adapted to the host are candidate unculturable species. With the enormous potential for discovery, development, and market value of marine derived compounds, supply of the products is a major limiting factor for further development.

• Ocean and Polar Research
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• 제38권4호
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• pp.287-294
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• 2016

Marine sponges have been a remarkably rich source of pharmacologically active and structurally diverse natural products. As a part of our continuing search for novel secondary metabolites of biomedical importance from marine invertebrate, we encountered the sponge Lipastrotethya sp. from Chuuk, Micronesia. The crude organic extract of this animal exhibited considerable cytotoxicity against the K562 cell line. Guided by the $^1H$ NMR analysis, flash chromatography of the crude extract followed by HPLC yielded a new triterpene glycoside, along with ten known saponins of the sarasinoside class. The structure of this new compound was determined by combined spectroscopic methods such as COSY, HSQC and HMBC experiment. Among these metabolites, six compounds exhibited moderate cytotoxicity against ACHN, MDA-MB-231, NCI-H23 and NUGC-3 cell lines.

• Natural Product Sciences
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• 제5권4호
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• pp.177-180
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• 1999

The ethanolic extracts of two shallow water sponge species collected from the Aegean Sea afforded thirteen terpenoids in total, two of which were determined to be new. The structure elucidation of the terpenoids was carried out by spectroscopic techniques and comparison with related authentic compounds. The terpenoids have also been assayed for antibacterial activity. This is the first report about the metabolites isolated from the marine sponges of the Aegean Sea in Turkey.

• Animal Systematics, Evolution and Diversity
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• 제15권1호
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• pp.141-152
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• 1999

1994년 7월부터 1995년 9월까지 거문도와 부근섬으로부터 잠수부에 의해서 채집된 해산 해면류를 동정, 분류한 결과 1강 7목 19과 26속 36종으로 밝혀졌다. 이중 4종 Stelletta japonica Lebwohl, 1914(왜별해면), Caminella velata Lebwohl, 1914(껍질가마해면), Stylohalina hirta Topsent, 1898(거친침상해면) 그리고 Esperiopsis rugosa Thiele, 1905(주름발톱해면)이 한국 미기록종으로 판명되었다.

• Animal Systematics, Evolution and Diversity
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• 제29권2호
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• pp.129-135
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• 2013

Two species of crabs, Homola orientalis Henderson, 1888 and Pseudomicippe nipponica (Sakai, 1938), are described and illustrated for the first time in Korea. Homola orientalis was collected at 30 m depth by trap from Busan, and P. nipponica was collected on the intertidal region in Seongsanpo, Jejudo Island. Homola orientalis is the first species of its family in the region. The family Homoldae is characterized by a linea homolica on the carapace and they carry camouflage in the form of sponges or cnidarians with subchelate of the fourth ambulatory legs. The Korean brachyuran fauna now comprises 223 species including the new records from this study.

• Journal of Species Research
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• 제7권4호
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• pp.340-347
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• 2018

Four psammocinian species(Demospongiae: Dictyoceratida: Irciniidae) are described from Gageodo and Jejudo Islands, Korea. Among them, three are new species, Psammocinia rana, P. massa and P. vermins, which are very different from other recorded species. Secondary fibres of Psammocinia rana are mostly wide platelike shape with large perforation. Primary and secondary fibres of Psammocinia massa are lumped together in a thick mass through numerous areas. Psammocinia vemis is similar to P. mosulpia in skeletal structure, but differs in size of cored sands in primary fibres. The fourth species, we reclassify from Ircinia chupoensis to Psammocinia chupoensis based on more detailed observation of the skeletal structure. Ircinia only has sand cored primary fibres, while the observed species, has sand cored primary and secondary fibres.

• Animal cells and systems
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• 제8권4호
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• pp.247-250
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• 2004

A taxonomic study on marine sponges was conducted by SCUBA diving at Gageodo Island, Korea from August 1999 to July 2001. Among them, Haliclona (Gellius) coreana n. sp. turned out to be new to science. This new species seems to be close to H. (G.) arcoferus Vosmaer, 1885, based on the type of spicules. However, it is different in size of toxa and growth form. Toxa of the new species is half in length compared to H. (G.) arcoferus. The growth form is jar shaped in this new species, but flat in H. (G.) arcoferus.

• Animal cells and systems
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• 제8권2호
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• pp.71-75
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• 2004

A study on marine sponges was conducted by SCUBA diving at Ulleungdo Island, Korea, from July 2001 to August 2003. Two species, Mycale (Naviculina) ulleugensis and Mycale (N.) neunggulensis, are new to science. Mycale (N.) ulleugensis n. sp. seems close to M. chungae based on the shape of spicules, but differs in the size of megascleres and sigmas, Mycale (N.) neunggulensis n. sp. seems close to M. flagellifer Vacelet and Vasseur in the type and size of spicules, but differs in the shape of naviculichela. Naviculichela I of M. flagellifer has a spine on the upper part of the felix.

• Animal cells and systems
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• 제6권4호
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• pp.283-285
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• 2002

Sponges of the family Irciniidae are poorly known in Korean waters. This paper describes a new species of new genus, Bergquistia coreana n. sp. in the family Irciniidae (Demospongiae: Dictyoceratida) from Jejudo Island, Korea from 1998 to 1999. Bergquistra n. gen. is characterized by extremely simple fasciculated and uncored primary fibres. However, in the choano-somal region, primary fibres are made of wider clear web. Secondary fibres form a very thin regular uncored network. The sponge surface has thick and regular conules. The colour is beige throughout the sponge, and the texture is slightly hard and compressible. Thickness of filament is variable.

• Archives of Pharmacal Research
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• 제22권1호
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• pp.25-29
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• 1999

Psammaplin A, a natural bromotyrosine derivative from an associated form of two sponges (Poecillastra sp. and jaspis sp.) was found to possess the antimicrobial effect on the Gram-positive bacteria, especially on methicillin-resistant Staphylococcus aureus (MRSA). The minimal inhibitory concentration of psammaplin A against twenty one MRSAs ranged from 0.781 to 6.25 ${\mu}g/ml$, which that of ciprofloxacin was 0.391~3.125${\mu}g/ml$. Psammaplin A could not bind to penicillin binding protein, but inhibited the DNA synthesis and the DNA gyrase activity with the respective 50% (DNA synthesis) and 100% (DNA gyrase) inhibitory concentration 2.83 and 100 ${\mu}g/ml$. These results indicate that psammaplin A has a considerable antibacterial activity, although restricted to a somewhat narrow range of bacteria, probably by inhibiting DNA gyrase.