• Tuberculosis and Respiratory Diseases
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• 제84권4호
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• pp.274-281
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• 2021

Background: The Korea National Health and Nutrition Examination Survey (KNHANES) is a well-designed survey to collect national data, which many researchers have used for their studies. In KNHANES, although portable spirometry was used, its reliability has not been verified. Methods: We prospectively enrolled 58 participants from four Korean institutions. The participants were classified into normal pattern, obstructive pattern, and restrictive pattern groups according to their previous spirometry results. Lung function was estimated by conventional spirometry and portable spirometry, and the results were compared. Results: The intraclass correlation coefficients of forced vital capacity (FVC) (coefficient, 9.993; 95% confidence interval [CI], 0.988-0.996), forced expiratory volume in 1 second (FEV₁) (coefficient, 0.997; 95% CI, 0.995-0.998), FEV₁/FVC ratio (coefficient, 0.995; 95% CI, 0.992-0.997), and forced expiratory flow at 25-75% (FEF25-75%; coefficient, 0.991; 95% CI, 0.984-0.994) were excellent (all p<0.001). In the subgroup analysis, the results of the three parameters were similar in all groups. In the overall and subgroup analyses, Pearson's correlation of all the parameters was also excellent in the total (coefficient, 0.986-0.994; p<0.001) and subgroup analyses (coefficient, 0.915-0.995; p<0.001). In the paired t-test, FVC, FEV₁/FVC, and FEF25-75% estimated by the two instruments were statistically different. However, FEV₁ was not significantly different. Conclusion: Lung function estimated by portable spirometry was well-correlated with that estimated by conventional spirometry. Although the values had minimal differences between them, we suggest that the spirometry results from the KNHANES are reliable.

• Journal of Chest Surgery
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• 제19권2호
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• pp.188-196
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• 1986

Spirometry and regional function studies using 99m-Technetium were performed preoperatively to predict postoperative pulmonary function change in 34 patients who had various pulmonary resectional procedures at the Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital. Between two months and fourteen months postoperation all the patients were reinvestigated with spirometry and clinical examination to evaluate their functional respiratory status. The postoperative obtained values, especially forced vital capacity [FVC] and forced expiratory volume in one second [FEV1] among the other parameters were compared with the postoperative predicted values. Estimated values of FVC and FEV1 derived from preoperative spirometry and quantitative perfusion lung scan correlated well with the measured postoperative values. The linear regression line derived from correlation between postoperative estimated[X] and postoperative measured[Y] values of FVC and FEV1 in all patients are as follows; 1. Y=0.76x + 0.39 in correlation of FVC [r=0.91] 2. Y=0.88x + 0.17 in correlation of FEV1 [r=0.96],br> This method of estimation was one of the best methods of predicting postoperative pulmonary function change and valuable in determining the extent of safe resection and postoperative prognosis to a poor risk patient with chronic obstructive lung disease.

• Journal of Chest Surgery
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• 제26권8호
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• pp.609-612
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• 1993

Studies of pulmonary function using spirometry were performed before and after pneumonectomy for inflammatory lung diseases from 1985 to 1990 at the Pusan Paik Hospital, Inje Medical College. Fifty-two patients were evaluated ; 33 tuberculosis, 17 bronchiectasis, 2 abscess, and 1 actinomycosis. All patients had preoperative and postoperative FVC, FVC[% predicted], FEV1, %FEV1, MVV and MVV[%predicted] determinations. And above datas were compared each other statistically with applying of the paired t-test. The results were obtained as follows : there were significant decreased after surgery in the values of FVC, FVC[% predicted], MVV, and MVV[% predicted], but the values of FEV1, and %FEV1 were no significant changes after surgery.

• Tuberculosis and Respiratory Diseases
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• 제69권2호
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• pp.108-114
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• 2010

Background: The aim was to estimate the differences between pulmonary disability grades according to the spirometry reference equations (the Korean equation and the Morris equation). Methods: Spirometry was performed on 16,916 male and 1,353 female special examination for pneumoconiosis, in the period of 2007~2009. Changes in predictive values for forced expiratory volume in one second ($FEV_1$), forced vital capacity (FVC) and $FEV_1$/FVC and in disability grade were evaluated using both equations. Results: Mean FVCs for men and women were 4,218.7 mL and 2,801.5 mL in predictive values after the application of the Korean equation, and 3,763.9 mL and 2,395.6 mL after the Morris equation, respectively. Compared with the Morris equation, the Korean equation showed 10.8% and 14.5% of excesses for men and women (p<0.001). Mean $FEV_1s$ for men and women were 3,102.5 mL and 2,107.1 mL in the Korean equation, and 2,667.8 mL and 1,699.6 mL in the Morris equation, respectively. Compared with the Morris equation, the Korean equation showed 14.0% and 19.3% of excesses for men and women (p<0.001). Men and women who showed the changes of disability grades using the Korean equation in place of the Morris equation were 23.9% (4,052/16,916) and 22.9% (311/1,353) on FVC, and 23.1% (3,913/16,916) and 10.7% (145/1,353) on $FEV_1$. Conclusion: Applying different reference equations for spirometry has resulted in changes for disability grades in special examination for pneumoconiosis.

• Tuberculosis and Respiratory Diseases
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• 제72권3호
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• pp.302-309
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• 2012

Background: Korean regression models for spirometric reference values are different from those of Americans. Using spirometry results of Korean adults, goodness-of-fits of the Korean and the USA Caucasian regression models for forced vital capacity (FVC) and forced expiratory volume in one second ($FEV_1$) were compared. Methods: The number of study participants was 2,360 (1,124 males and 1,236 females). Spirometry was performed under the guidelines of the American Thoracic Society and the European Respiratory Society. After excluding unsuitable participants, spirometric data for 729 individuals (105 males and 624 females) was included in the statistical analysis. The estimated FVC and $FEV_1$ values were compared with those measured. Goodness-of-fits for Korean and USA Caucasian models were compared using an F-test. Results: In males, the expected values of FVC and $FEV_1$ using the Korean model were 12.5% and 5.7% greater than those measured, respectively. The corresponding values for the USA Caucasian model were 3.5% and 0.6%. In females, the difference in FVC and $FEV_1$ were 13.5% and 7.7% for the Korean model, and 6.3% and 0.4% for the USA model, respectively. Goodness-of-fit for the Korean model regarding FVC was not good to the study population, but the Korean regression model for $FEV_1$, and the USA Caucasian models for FVC and $FEV_1$ showed good fits to the measured data. Conclusion: These results suggest that the USA Caucasian model correlates better to the measured data than the Korean model. Using reference values derived from the Korean model can lead to an overestimation regarding the prevalence of abnormal lung function.

• Tuberculosis and Respiratory Diseases
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• 제58권3호
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• pp.230-242
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• 2005

연구배경 : 우리나라 국민을 대상으로 실시한 폐활량검사의 판정과 해석은 우리나라 국민을 대상으로 구한 폐활량 예측식이 사용되어야 한다. 그 동안 외국인을 대상으로 구한 폐활량 예측치가 사용되어 오류가 있었다. 본 연구에서는 전 국민을 대상으로 대표성 있고 신뢰할 수 있는 노력성 폐활량과 일초간 노력성 폐활량, 6초간 노력성 폐활량, 일초율에 대한 정상 예측식을 개발 하고자 하였다. 연구방법 : 전 국민을 대상으로 층화표본 추출법을 사용하여 조사대상을 선정하였으며, 폐활량검사기와 검사방법, 검사과정, 결과의 선택을 미국흉부학회에서 권고하는 기준에 따라 체계적인 정도관리와 질관리를 실시하였다. 폐활량 검사를 실시한 대상자 4,816명 중에서 비흡연자이면서 폐활량에 영향을 미칠 수 있는 호흡기 질환 및 증상이 없고, 흉부방사선학적 검사에서 심폐 이상 소견이 없으면서, 폐활량에 영향을 미치는 유해인자에의 노출력이 없는 대상자는 1,212명으로 남자 206명, 여자 1,006명이었다. 이들은 지역과 연령별로 우리나라 국민을 대표할 수 있었다. 통계분석에서 혼합효과모델을 적용하여 AIC 값이 가장 작은 모델로서 남자와 여자에 공통적으로 포함된 변수들을 일반선형회귀분석에 적용하여 폐활량 예측식을 구하였다. 결 과 : 노력성 폐활량의 예측식은 남자 -4.8434 - 0.00008633*연령$^2$(년) + 0.05292*신장(cm) + 0.01095*체중(kg)이었으며, 여자 -3.0006 - 0.0001273 *연령$^2$(년) + 0.03951*신장(cm) + 0.006892*체중(kg)이었다. 일초간 노력성 폐활량의 예측식은 남자 -3.4132 -0.0002484*연령$^2$(년) + 0.04578*신장(cm)이었으며, 여자 -2.4114 - 0.0001920*연령$^2$(년) + 0.03558*신장(cm)이었다. 6초간 노력성 폐활량의 예측식은 남자 -4.4244 -0.0001367*연령$^2$(년) + 0.05156*신장(cm) + 0.008246*체중(kg)이었으며, 여자 -3.1433 - 0.0001442*연령$^2$(년) + 0.04018*신장(cm) + 0.007077*체중(kg)이었다. 일초율의 예측식은 남자 119.9004 - 0.3902*연령(년) - 0.1268*신장(cm)이었으며, 여자 97.8567 - 0.2800*연령(년) - 0.01564*신장(cm)이었다. 결 론 : 본 예측식은 미국흉부학회에서 제시하고 있는 연령과 신장 변수에 체중이 포함되어 차이가 있었다. 이러한 이유는 연령효과와 젊은 연령에서 신장과 체중이 급격하게 변화하는 체격효과가 복합적으로 작용하기 때문이라고 해석된다. 본 예측식과 다른 국내 및 국외 예측식을 비교할 때 본 예측식이 노력성 폐활량과 일초간 노력성 폐활량, 일초율의 예측치를 높게 추정하였으나 대부분 그 차이가 10% 이내로 비슷하였다. 코카시안인 백인을 대상으로 구한 외국의 예측식보다 본 연구의 정상 예측치가 낮지 않았다. 이러한 이유로는 우리나라 젊은 사람들의 체격조건의 변화와 함께 엄격한 정상인의 선정기준, 검사방법과 검사결과의 정도관리 및 질관리에 기인하는 것으로 판단되었다.

• Tuberculosis and Respiratory Diseases
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• 제63권5호
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• pp.405-411
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• 2007

연구배경: 본 연구를 통해 2005년도 ATS/ERS 폐활량검사 지침에서 제시한 재현성 기준을 한국 성인들에게 적용할 수 있는 지와, 한국 성인들의 폐활량 검사 시 재현성에 영향을 미치는 요인들을 알아보고자 하였다. 방 법: 국민건강영양조사, COPD 코호트, 지역사회 코호트로부터 얻은 성인 4,663명의 폐활량검사 결과를 이용하여 dFVC 및 $dFEV_1$를 계산하여 분포를 알아보고, 1994년도 ATS 지침 및 2005년도 ATS/ERS 지침을 만족하는 검사의 비율을 비교하였다. 다중회귀분석을 통해 개인적 특성 및 재현성 기준의 변화가 재현성에 영향을 미치는가를 알아보았다. 결 과: 폐활량검사를 시행한 사람들 중 95% 이상이 150ml 이내의 재현성 기준을 만족시켰다. 1994년도 ATS 지침에 따라 검사를 시행한 경우 재현성을 만족하지 않는 경우가 증가하였다. 다중회귀분석 결과 재현성에 영향을 주는 요인들은 신장, 연령, 체중, 폐쇄성폐질환 여부, 재현성 기준의 변화 등이었으나 재현성에 영향을 미치는 정도는 매우 작았다(0.5~3.0%). 결 론: 한국인에게도 2005년도 ATS/ERS에서 제시한 재현성 기준을 적용할 수 있을 것으로 생각하며, 이를 위해서는 변경된 재현성 기준에 대한 지속적인 홍보와 검사자 들에 대한 교육 및 정도 관리가 필요하다.

• PNF and Movement
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• 제18권2호
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• pp.297-303
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• 2020

Purpose: The purpose of this study was to examine the effects of inhalation and exhalation exercise combined with upper extremity proprioceptive neuromuscular facilitation pattern on two spirometry values: forced volume vital (FVC) and peak expiratory flow (PEF). Methods: Thirty-two healthy adults were divided into two groups: 1) a combined group, which performed upper extremity D2 flexion pattern (shoulder flexed/abducted/external rotated, forearm supinated, wrist radial deviated, and finger extended) during exhalation and D2 extension pattern (shoulder extended/adducted/internal rotated, forearm pronated, wrist ulnar deviated, and finger flexed) during inhalation; and 2) reverse combined group, which performed the D2 flexion pattern during inhalation and the D2 extension pattern during exhalation. The inverse application of upper extremity movements during inhalation and exhalation induced selective resistance or assistance on respiration. FVC and PEF were measured at two time points, before and after four weeks. Results: In both groups, the pre-post intervention comparison showed significant increases in FVC and PEF (p < .05). In the between-groups comparison, the reverse combined group showed a significantly higher PEF than the combined group at four weeks post intervention (p < 0.05). Conclusion: The combined respiration exercise with reverse PNF upper extremity patterns using selective resistance showed an effective increase in PEF in healthy adults. Clinicians and researchers might consider using selective resistance as a widely applicable and cost-effective option for respiratory rehabilitation planning.

• Journal of Chest Surgery
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• 제24권4호
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• pp.338-344
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• 1991

If the postoperative pulmonary function can be predicted in the patients undergoing pneumonectomy for lung cancer preoperatively, it will be helpful for identifying them as high or low risk candidates. Perfusion lung scan and spirometry were performed in 12 patients with lung cancer pre-operatively and the predicted postoperative Vital Capacity, FVC, FEV1.0, FEF25 - 75% and MVV were estimated by multiplying the preoperative values by the percentage of perfusion of the nonsurgical lung. Three months postoperation the patients were reinvestigated with spirometry and the obtained values were compared with the predicted values. The linear regression lines derived from the correlation between predicted values [X] and observed values [Y] were as follows; VC; R=0.532, Y=0.48X+1.28, P=0.075 FVC; R=0.566, Y=O 54X+1.15, P=0.055 FEV1.0; R=0.832, Y=0.68X+0.70, P=0.001 FEF25 ~ 75%; R=0.781, Y=0.68X+0.54, P=0.003 MVV; R=0.718, Y=0.67X+34.75, P=0.009 The prediction of postoperative FEV1.0, FEF25 ~ 75% and MVV in lung cancer patients undergoing pneumonectomy appear to be valid for evaluating preoperative pulmonary function.

• 대한임상검사과학회지
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• 제55권1호
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• pp.29-36
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• 2023

이 연구는 특수건강진단 폐활량검사 시 아시안 외국인 근로자들에게 적절한 예측식을 제안하는 것이다. 연구 대상은 지리적 분포에 따라 중앙아시아, 동북아시아, 남아시아태평양 그룹으로 나누었으며, 그룹별 폐활량검사 결과와 예측식간 일치도를 확인하였다. 이를 기준으로 국내 외국인 근로자들에게 폐활량검사 시 적절한 예측식을 제안하였고, 제안한 예측식을 적용할 수 없는 폐활량검사기에는 보정계수를 제안하였다. Global lung function initiative 2012 (GLI2012)-동북아시안식과 동남아시안식의 해석일치도는 남성 0.819, 여성 0.770이었고, GLI2012-동남아시안식과 남아시안식의 해석 일치도는 남성 0.881, 여성 0.886이었다. GLI2012-동북아시안식과 중앙아시안식의 해석일치도는 남성 0.831, 여성 0.833이었다. 따라서 동북아시안, 중앙아시안 그룹에 속하는 외국인 근로자는 GLI2012-동북아시안식을 적용하고, 동남아시안, 남아시안 그룹에 속하는 외국인 근로자는 GLI2012-동남아시안식을 제안한다. GLI2012-동남아시안식을 선택할 수 없는 폐활량검사기의 경우 최정근식(Dr. Choi equation)에 보정계수 0.87을 적용할 것을 제안한다.