• Annals of Clinical Neurophysiology
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• 제19권1호
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• pp.58-63
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• 2017

Studies of interictal epileptiform discharges are essential for improving the diagnosis, classification, and management of epilepsy. In this case series we sought to identify the clinical and neurophysiological significance of bifid spikes, whose pattern bears a strong resemblance to the cardiac M pattern. We hypothesize that, analogous to the cardiac M pattern, the cerebral M pattern is generated by a conduction defect associated with asynchronous spatiotemporal averaging of electrical signals in the cortex, resulting in the signals reaching the scalp with different latencies. Unlike the cardiac M pattern, the pathology underlying the cerebral M pattern is unknown, although congenital CNS anomalies may be a culprit.

• 대한전기학회논문지
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• 제38권4호
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• pp.269-278
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• 1989

When the induction motor is operated by CSI, the commutation capacitance in the CSI circuit is increased according to the increase of large capacitor system. The output voltage spikes are generated at the moment of charge and discharge of the commutation capacitor. Also, since output current comprise a great number of harmonics, torque ripples of the motor are generated, having bad effects on the motor. In this study, by adopting the 18-phase multiple high Frequency Current Source Inverter (HFCSI), torque ripples generated by the voltage spikes are mostly eliminated except the 17th and 19th harmonics. To reduce the voltage spikes comprised in the output voltage, particularly, the methods of eliminating the cause of bad effect upon the motor are proposed in this paper. In the proposed method, by using additional voltage Clamping Curcuit (VCC), it is possible to select the values of commutation capacitor energy loss in commutating, the commutating capacitor, and the capacitor in the clamping circuit.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집B
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• pp.330-334
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• 2001

This paper presents the way of building an occupancy grid map which a mobile robot needs to autonomously navigate in the unknown environment. A disparity map resulting from stereo matching can be converted into the 2D distance information. If the stereo matching has some errors, however, the subsequent map becomes unreliable. In this paper, a new morphological filter is proposed to reject 'spikes' of the disparity map due to stereo mismatch by considering the fact that these spikes occur locally. The new method has advantages that it is simpler and more easily realized than existing similar algorithms.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2007년도 한국컴퓨터종합학술대회논문집 Vol.34 No.1 (B)
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• pp.5-8
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• 2007

본 논문은 스파이크 뉴런의 응답 모델에 대하여 논의한다. 먼저, 스파이크 뉴런의 코딩 방법과 스파이크 기능에 대하여 논의하고, 커널 함수의 중첩(superposition)에 의한 스파이크 뉴런의 활동 전위 구성에 대하여 논의한다. 이 방법은 IF(Integrate-and-Fire) 뉴런 모델에서 사용하는 활동 전위 방정식보다 일반적인 것이라는 것을 설명하였다. 다음에 스파이크 출력의 기능으로서 우연성 동시 검출과 가중치 계산을 논의하고 뉴런 집단(population)의 스파이크 출력에 대하여 논의한다.

• Journal of Yeungnam Medical Science
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• 제2권1호
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• pp.71-75
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• 1985

1985년 1월부터 10월까지 본 영남대학교 의과대학 부속병원 신경과 외래를 찾은 두통환자 중에서 뇌파상 중등도 이상의 이상이 있는 환자가 580명이었다. 이들 중에서 간질의 간헐기 뇌파와 유사한 소견을 보이는 162명 환자들을 대상으로 투여한 항간제 및 뇌영양제 등을 단독 혹은 병용 투여한 한 후 치료효과를 분석한 결과 항간제투여군 29예에서 호전이 16예, 무변화가 13예이고, 항간제를 쓰지 않고 뇌 영양제를 사용했던 18예에서는 전예에서 호전을 보았다. 한편 항간제를 사용한 33예와 사용하지 않은 35예에서는 뇌파추적을 하지 못하였다. 수가 적어서 통계학적인 고찰은 하지 않았으며 앞으로 계획석인 계속 연구가 요망된다.

• The Korean Journal of Physiology and Pharmacology
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• 제21권5호
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• pp.555-563
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• 2017

Electrical stimulation through retinal prosthesis elicits both short and long-latency retinal ganglion cell (RGC) spikes. Because the short-latency RGC spike is usually obscured by electrical stimulus artifact, it is very important to isolate spike from stimulus artifact. Previously, we showed that topographic prominence (TP) discriminator based algorithm is valid and useful for artifact subtraction. In this study, we compared the performance of forward backward (FB) filter only vs. TP-adopted FB filter for artifact subtraction. From the extracted retinae of rd1 mice, we recorded RGC spikes with $8{\times}8$ multielectrode array (MEA). The recorded signals were classified into four groups by distances between the stimulation and recording electrodes on MEA (200-400, 400-600, 600-800, $800-1000{\mu}m$). Fifty cathodic phase-$1^{st}$ biphasic current pulses (duration $500{\mu}s$, intensity 5, 10, 20, 30, 40, 50, $60{\mu}A$) were applied at every 1 sec. We compared false positive error and false negative error in FB filter and TP-adopted FB filter. By implementing TP-adopted FB filter, short-latency spike can be detected better regarding sensitivity and specificity for detecting spikes regardless of the strength of stimulus and the distance between stimulus and recording electrodes.

• The Korean Journal of Physiology and Pharmacology
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• 제15권6호
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• pp.415-422
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• 2011

Previously, we reported that besides retinal ganglion cell (RGC) spike, there is ~10 Hz oscillatory rhythmic activity in local field potential (LFP) in retinal degeneration model, rd1 mice. The more recently identified rd10 mice have a later onset and slower rate of photoreceptor degeneration than the rd1 mice, providing more therapeutic potential. In this study, before adapting rd10 mice as a new animal model for our electrical stimulation study, we investigated electrical characteristics of rd10 mice. From the raw waveform of recording using $8{\times}8$ microelectrode array (MEA) from in vitro-whole mount retina, RGC spikes and LFP were isolated by using different filter setting. Fourier transform was performed for detection of frequency of bursting RGC spikes and oscillatory field potential (OFP). In rd1 mice, ~10 Hz rhythmic burst of spontaneous RGC spikes is always phase-locked with the OFP and this phase-locking property is preserved regardless of postnatal ages. However, in rd10 mice, there is a strong phase-locking tendency between the spectral peak of bursting RGC spikes (~5 Hz) and the first peak of OFP (~5 Hz) across different age groups. But this phase-locking property is not robust as in rd1 retina, but maintains for a few seconds. Since rd1 and rd10 retina show phase-locking property at different frequency (~10 Hz vs. ~5 Hz), we expect different response patterns to electrical stimulus between rd1 and rd10 retina. Therefore, to extract optimal stimulation parameters in rd10 retina, first we might define selection criteria for responding rd10 ganglion cells to electrical stimulus.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.199-199
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• 2017

This study investigated the aspects of damage due to low temperature treatment in order to establish the damage criterion according to low temperature invasion during regeneration period in wheat after regeneration period in the early spring. We cultivated wheat cultivar 'Geumgang' in Wagner pots and treated them with three types of low temperature, and the gradual temperature change program was set in a low temperature incubator for 12.5 h per day for 5 days during the night time when the length of young spikes was about 1 mm. All treatments except for the control were treated in 5 steps for each temperature. Treatment 1 was treated at the lowest temperature $-5^{\circ}C$ for 5 h, treatment 2 for 7 h at $-5^{\circ}C$, and treatment 3 for 9 h at $-5^{\circ}C$. The most common type of damage was partial infertility, and there were some discolored spikes. The damage rate of wheat spikes treated at $-5^{\circ}C$ for 9 h was the highest, while the damage rates of wheat sprouts treated at 5h and 7h were not different from each other. It was found that the damage of wheat spikes exposed to low temperatures for a long time was large. It is necessary to investigate the aspects of spike damage by duration days of low temperature.

• 전자공학회논문지S
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• 제35S권2호
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• pp.70-78
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• 1998

Spike detection in long-term EEG monitoring forepilepsy by wavelet transform(WT), artificial neural network(ANN) and the expert system is presented. First, a small set of wavelet coefficients is used to represent the characteristics of a singlechannel epileptic spikes and normal activities. In this stage, two parameters are also extracted from the relation between EEG activities before the spike event and EEG activities with the spike. then, three-layer feed-forward network employing the error back propagation algorithm is trained and tested using parameters obtained from the first stage. Spikes are identified in individual EEG channels by 16 identical neural networks. Finally, 16-channel expert system based on the context information of adjacent channels is introducedto yield more reliable results and reject artifacts. In this study, epileptic spikes and normal activities are selected from 32 patient's EEG in consensus among experts. The result showed that the WT reduced data input size and the preprocessed ANN had more accuracy than that of ANN with the same input size of raw data. Ina clinical test, our expert rule system was capable of rejecting artifacts commonly found in EEG recodings.

• 한국정밀공학회지
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• 제19권5호
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• pp.36-42
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• 2002

This paper presents the way of building an occupancy grid map which a mobile robot needs to autonomously navigate in the unknown environment. A disparity map resulting from stereo matching can be converted into the 2D distance information. If the stereo matching has some errors, however, the subsequent map becomes unreliable. In this paper, a new morphological filter is proposed to reject 'spikes' of the disparity map due to stereo mismatch by considering the fact that these spikes occur locally. The new method has advantages that it is simpler and more easily realized than existing similar algorithms. Several occupancy grid maps based on stereo vision using the proposed algorithm have been built and compared with the actual distance information to verify the validity of the proposed method.