• 아시안잔디학회지
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• 제11권3호
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• pp.205-210
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• 1997

The metal spikes evaluated in this study significantly affected more negative on the turf wear and ball speed of putting green than alternative plastic spikes. 1.The metal spikes caused the most amount of wear compared with plastic spikes, athletic shoes and mountain-climbing shoes. On the other hand, athletic shoes caused the least amount of wear. Plastic spikes caused wear more than athletic shoes, hut apparently wear less than metal spikes. The wear from metal spike repaired later than any other tread types. 2.The wear from all kinds of shoe treads in wetcondition green were higher than in dry-condition green and the wear from metal spikes was more severe compared with plastic spikes in both green condition. 3. Ball speed of heavy compaction area by metal spike was reduced about 9% compared with that of light compaction area, hecause metal spikes made many holes in the putting green surface. On the other hand, plastic spikes did not affect hall speed of heavy and light compaction area in the putting green. Key words: Metal spike, Plastic spike, Wear, Ball speed.

• 한국작물학회지
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• 제40권2호
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• pp.245-249
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• 1995

보리, 밀, 등을 수확기에 보면 미열이삭이 생기는데 이 미열이삭의 수가 품종간에 차이를 나타내는 것인가 하는 문제와 그렇다면 그의 유전력은 어떠하며 다른 형질들과의 상관은 어떻게 나타날 것인가에 대한 조사를 한 결과는 아래와 같다. 1. 보리의 미열이삭수는 찰보리가 평균 6도로서 제일 많았고 조강보리와 새올보리가 평균 1도로서 제일 적어 품종간차가 뚜렷하였다. 2. 밀의 미열이삭수도 탑동밀이 3.6도로서 제일 많았고 조광이 1.4도로서 제일 적어 품종간차가 분명하였다. 3. 보리의 미열이삭수의 유전력은 0.85로서 상당히 높았으며 밀은 0.65로서 보리보다는 약간 낮았으나 두 작물 모두 비교적 높은 유전력을 나타내었다. 4. 보리의 미열이삭수는 절간수와 고도의 유의성이 있는 상관을 나타내었고, 지엽장과도 유의성이 있는 상관을 나타내었으나 다른 형질들과는 상관이 낮거나 부의 상관을 나타내었다. 5. 말의 미열이삭과 절간수와의 사이에는 유의성있는 부의 상관을 나타내었고 미열이삭과 다른 형질들 사이에는 상관이 없었다.

• The Korean Journal of Physiology and Pharmacology
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• 제26권6호
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• pp.531-540
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• 2022

Group 1 metabotropic glutamate receptors (mGluRs) can positively affect postsynaptic neuronal excitability and epileptogenesis. The objective of the present study was to determine whether group 1 mGluRs might be involved in synaptically-induced intracellular free Ca²⁺ concentration ([Ca²⁺]_i) spikes and neuronal cell death induced by 0.1 mM Mg²⁺ and 10 µM glycine in cultured rat hippocampal neurons from embryonic day 17 fetal Sprague-Dawley rats using imaging methods for Ca²⁺ and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assays for cell survival. Reduction of extracellular Mg²⁺ concentration ([Mg²⁺]_o) to 0.1 mM induced repetitive [Ca²⁺]_i spikes within 30 sec at day 11.5. The mGluR5 antagonist 6-Methyl2-(phenylethynyl) pyridine (MPEP) almost completely inhibited the [Ca²⁺]_i spikes, but the mGluR1 antagonist LY367385 did not. The group 1 mGluRs agonist, 3,5-dihydroxyphenylglycine (DHPG), significantly increased the [Ca²⁺]_i spikes. The phospholipase C inhibitor U73122 significantly inhibited the [Ca²⁺]_i spikes in the absence or presence of DHPG. The IP₃ receptor antagonist 2-aminoethoxydiphenyl borate or the ryanodine receptor antagonist 8-(diethylamino)octyl 3,4,5-trimethoxybenzoate also significantly inhibited the [Ca²⁺]_i spikes in the absence or presence of DHPG. The TRPC channel inhibitors SKF96365 and flufenamic acid significantly inhibited the [Ca²⁺]_i spikes in the absence or presence of DHPG. The mGluR5 antagonist MPEP significantly increased the neuronal cell survival, but mGluR1 antagonist LY367385 did not. These results suggest a possibility that mGluR5 is involved in synaptically-induced [Ca²⁺]_i spikes and neuronal cell death in cultured rat hippocampal neurons by releasing Ca²⁺ from IP₃ and ryanodine-sensitive intracellular stores and activating TRPC channels.

• 산업공학
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• 제23권2호
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• pp.176-181
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• 2010

Warranty claim data analysis is a useful tool for the manufacturer because it contains many useful informations regarding reliability of the product in the real-world environments. Because of the nature of uncertainty and the incompleteness of data, some bias patterns are observed on warranty claim rate known as 'spikes'. Two types of spikes are considered. One is due to manufacturing-related failures. The other is caused by customer's behavior. This paper proposes a model by considering two types of spikes. Warranty claim data is analyzed with the proposed model. To represent spikes observed on the early warranty period, we classify failures into manufacturing-related failures and usage-related failures. Uniform distribution is assumed for the time delayed to diagnose and report by customers. By reducing maximum value of the delayed time by customers, the proposed model characterizes customer's rush in the vicinity of the warranty expiration limit. Experimental results by using the real warranty claim data show that the proposed model is better than the existing one in respect to MSE(Mean Squared Error). Moreover it is expected to estimate the failure rate more realistically with proposed model because it considers the delayed time to diagnose and report by customers.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 추계학술대회
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• pp.203-206
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• 1996

During the electromyographic evaluation, the presence and site of lession may be predicted by a detection of denervation potentials such as fibrllation potentials or positive sharp waves in the group of muscles. Currently, clinicians diagnose the neuropathy by detecting fibrillation potentials during EMG tests, and sometimes it is not easy to distinguish between denervation potentials and endplate spikes. The purpose of this study was to find statistically significant parameters for the quantitative distinction between denervation potentials and endplate spikes. Endplate spikes and denervation potentials from the EDB muscle of 10 patients were extracted. Also, EMG signals were classified by experienced clinicians, and were collected using a 12 bit ADC with a sampling rate of 20KHz for the duration of 400msec. In order to find statistically significant parameters, positive and negative peaks were used for analysis. As a results, standard deviation of the endplate spikes and denervation potentials showed more significant difference than others specially for the positive sharp waves. It was concluded that the results of this study could be used to develope an automated system of a EMG analysis.

• Journal of Power Electronics
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• 제19권3호
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• pp.727-743
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• 2019

This paper presents a pulse-width modulation strategy to eliminate the common mode voltage (CMV) with reduced CMV spikes in multilevel inverters since a high CMV magnitude and its fast variations dv/dt result in bearing failure of motors, overvoltage at motor terminals, and electromagnetic interference (EMI). The proposed method only utilizes the zero CMV states in a space vector diagram and it is implemented by a carrier-based pulse-width modulation (CBPWM) method. This method is generalized for odd number levels of inverters including neutral-point-clamped (NPC) and cascaded H-bridge inverters. Then it is extended to the over-modulation mode. The over-modulation mode is implemented by using the two-limit trajectory principle to maintain linear control and to avoid look-up tables. Even though the CMV is eliminated, CMV spikes that can cause EMI and bearing current problems still exist due to the deadtime effect. As a result, the deadtime effect is analyzed. By taking the deadtime effect into consideration, the proposed method is capable of reducing CMV spikes. Simulation and experimental results verify the effectiveness of the proposed strategy.

• The Korean Journal of Physiology and Pharmacology
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• 제20권1호
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• pp.101-109
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• 2016

Reducing $[Mg^{2+}]_o$ to 0.1 mM can evoke repetitive $[Ca^{2+}]_i$ spikes and seizure activity, which induces neuronal cell death in a process called excitotoxicity. We examined the issue of whether cultured rat hippocampal neurons preconditioned by a brief exposure to 0.1 mM $[Mg^{2+}]_o$ are rendered resistant to excitotoxicity induced by a subsequent prolonged exposure and whether $Ca^{2+}$ spikes are involved in this process. Preconditioning by an exposure to 0.1 mM $[Mg^{2+}]_o$ for 5 min inhibited significantly subsequent 24 h exposure-induced cell death 24 h later (tolerance). Such tolerance was prevented by both the NMDA receptor antagonist D-AP5 and the L-type $Ca^{2+}$ channel antagonist nimodipine, which blocked 0.1 mM $[Mg^{2+}]_o$-induced $[Ca^{2+}]_i$ spikes. The AMPA receptor antagonist NBQX significantly inhibited both the tolerance and the $[Ca^{2+}]_i$ spikes. The intracellular $Ca^{2+}$ chelator BAPTA-AM significantly prevented the tolerance. The nonspecific PKC inhibitor staurosporin inhibited the tolerance without affecting the $[Ca^{2+}]_i$ spikes. While $G{\ddot{o}}6976$, a specific inhibitor of $PKC{\alpha}$ had no effect on the tolerance, both the $PKC{\varepsilon}$ translocation inhibitor and the $PKC{\zeta}$ pseudosubstrate inhibitor significantly inhibited the tolerance without affecting the $[Ca^{2+}]_i$ spikes. Furthermore, JAK-2 inhibitor AG490, MAPK kinase inhibitor PD98059, and CaMKII inhibitor KN-62 inhibited the tolerance, but PI-3 kinase inhibitor LY294,002 did not. The protein synthesis inhibitor cycloheximide significantly inhibited the tolerance. Collectively, these results suggest that low $[Mg^{2+}]_o$ preconditioning induced excitotoxic tolerance was directly or indirectly mediated through the $[Ca^{2+}]_i$ spike-induced activation of $PKC{\varepsilon}$ and $PKC{\xi}$, JAK-2, MAPK kinase, CaMKII and the de novo synthesis of proteins.

• 한국지구과학회지
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• 제30권4호
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• pp.454-463
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• 2009

본 연구에서는 2006년 1월부터 2009년 2월까지 자연 상태에서 만들어진 솟는 고드름(n=107)을 관측, 분석하여 실험실에서 솟는 고드름을 재현할 수 있는 실험 장치를 개발했다. 이 장치를 이용하여 동영상 관측과 실험(531개의 솟는 고드름 생성)을 통해 그 생성과 성장 원리를 연구했다. 용기의 아래 부분이 위쪽 보다 더 차가운 상태에서 용기 바닥과 물 표면에서부터 얼음이 얼기 시작하는데, 표면에서 얼음이 얼지 않는 부분을 숨구멍이라고 하며 이곳으로부터 솟는 고드름이 만들어지기 시작한다. 솟는 고드름이 만들어지기 시작한 후 계속 성장하기 위해서는 용기 하부의 물이 얼음으로 변할 때의 부피 팽창 효과와 숨구멍을 통해 올라오는 과냉각수의 빠른 빙결 효과 등이 관련된다. 실험 장치에서 아이스 트레이 큐브에 증류수를 넣고, -12- $-13^{\circ}C$의 온도를 약 1시간 30분 정도 유지시키면 수면에 살얼음과 숨구멍이 생기기 시작한다. 숨구멍으로부터 생기기 시작한 솟는 고드름은 10-30분 동안 성장하고, 끝이 막히면서 성장을 멈춘다. 솟는 고드름의 형태는 7가지로 분류되며 자연 상태에서는 꼭지형과 기운형이 많았고, 실험실에서는 수직형이 가장 많았다.

• 대한의용생체공학회:의공학회지
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• 제2권2호
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• pp.83-88
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• 1981

A method of detecting abnormal spikes occuring in the EEG of subjects suffering from epilepsy is studied. The detection scheme is to take the first derivative of EEG and to determine if it exceed some threshold value. This study is focused on the digital signal processing for detecting abnormal spikes using microcomputer.

• The Korean Journal of Physiology and Pharmacology
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• 제5권3호
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• pp.213-221
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• 2001

The amygdala is known as a site for inducing analgesia, but its action on the trigeminal nucleus has not been known well. Little information is available on the effect of dynorphin on NMDA receptor-mediated electrophysiological events in the trigeminal nucleus. The purpose of this study was to investigate the changes in the single neuron spikes at the trigeminal nucleus caused by the amygdala and the action of dynorphin on the trigeminal nucleus. In the present study, extracellular single unit recordings were made in the dorsal horn of the medulla (trigeminal nucleus caudalis) and the effects of microiontophoretically applied compounds were examined. When [D-Ala2, N-Me-Phe4, Glys5-ol]enkephalin (DAMGO, 10-25 mM), a ${\mu}-opioid$ receptor agonist, was infused into the amygdala, the number of NMDA-evoked spikes at the trigeminal nucleus decreased. However, the application of naloxone into the trigeminal nucleus while DAMGO being infused into the amygdala increased the number of spikes. Low dose (1 mM) of dynorphin in the trigeminal nucleus produced a significant decrease in NMDA-evoked spikes of the trigeminal nucleus but the NMDA-evoked responses were facilitated by a high dose (5 mM) of dynorphin. After the ${\kappa}$ receptors were blocked with naloxone, dynorphin induced hyperalgesia. After the NMDA receptors were blocked with AP5, dynorphin induced analgesia. In conclusion, dynorphin A exerted dose-dependent dual effects (increased & decreased spike activity) on NMDA-evoked spikes in the trigeminal nucleus. The inhibitory effect of the dynorphin at a low concentration was due to the activation of ${\kappa}$ receptors and the excitatory effect at a high concentration was due to activation of NMDA receptors in the trigeminal neurons.