• Journal of the korean academy of Pediatric Dentistry
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• v.28 no.2
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• pp.219-227
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• 2001

Little is known about processing mechanism of pain sensation of the oral cavity at the 1st synapse of trigeminal sensory nuclei. Serial ultrathin sections of tooth pulp afferent terminals, identified by the transganglionic transport of 1% wheatgerm agglutinin conjugated horseradish peroxidase, were investigated with electron microscope. Quantitative ultrastructural analysis was performed on digitizing tablet connected to Macintoshi personal computer (software; NIH Image 1.60, NIH, Bethesda, MD). Labeled boutons could be classified into two types by the shapes of containing vesicles : S bouton, which contained mainly spherical vesicles (Dia. 45-55 nm) and few large dense cored vesicles (Dia, 80-120nm), and LDCV bouton, which contained spherical vesicles as well as large number of large dense cored vesicles. Most of the parameters on the ultrastructural characteristic and synaptic organization of labeled boutons were similar between S and LDCV boutons, except shapes of containing vesicles. Majority of the labeled boutons showed simple synaptic arrangement. The labeled boutons were frequency presynaptic to dendritic spine, and to a lesser extent, dendritic shaft. They rarely synapsed with soma and adjacent proximal dendrite. A small proportion of labeled boutons made synaptic contacts with presynaptic, pleomorphic vesicles containing endings and synaptic triad. Morphometric parameters of labeled boutons including volume and surface area, total apposed area, mitochondrial volume, active zone area, vesicle number and density showed wide variation and these were not significantly different between S and LDCV boutons. The present study revealed characteristic features on ultrastructure and synaptic connection of pulpal afferents which may involved in transmission of oral pain sensation.

• Progress in Medical Physics
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• v.9 no.3
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• pp.175-184
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• 1998

The dose distribution evaluation program for the stereotactic radiosurgery treatment planning system using a gamma knife has been built in order to work on PC. And this custom-made dose distribution is compared with that of commercial treatment planning program. 201 source position of a radiation unit were determined manually using a gamma knife collimator draft and geometrical coordinates. Dose evaluation algorithm was modified for our purpose from the original KULA, a commercial treatment planning program. With the composed program, dose distribution at the center of a spherical phantom, 80 mm in diameter, was evaluated into axial, coronal and sagittal image per each collimator. Along with this evaluated data, the dose distribution at a arbitrary point of inside the phantom was compared with those from KULA. Radiochromic film was set up at the center of the phantom and was irradiated by gamma knife, for the verification of dose distribution. In result, the deviation of the dose distribution from that of KULA is less than ${\pm}$3%, which is equivalent to ${\pm}$0.3 mm in 50% isodose distribution for all examined coordinates and film verification. The custom-made program, GPl is proven to be a good tool for the stereotactic radiosurgery treatment planning program.

• Journal of Korean Ophthalmic Optics Society
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• v.8 no.2
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• pp.57-63
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• 2003

To investigate the RMS SD(Root Mean Square Spot Diameter) in a back focal plane as the front surface power, the center thickness, and the refraction index vary, we use programs which are Cove V and LOSA 2.0, and consider a spectacle lens with back vertex power of -4.00D and diameter of 70 mm. We also consider the front surface power varied from 0.00 to 10.00D, the center thickness varied from 1.1 to 2.0 mm, and the indices which are $n_d$ = 1.498, 1.523, 1.586, and 1.660, respectively. As the front surface power increases the RMS SD in the back focal plane increase rapidly. When the refraction index increases, the RMS SD in the back focal plane decrease and the variation of RMS SD in the back focal plane decreases as the front surface power increases. When the center thickness of spectacle lens increases, the RMS SD in the back focal plane is constant and the edge thickness of that increases. We know from these results that the image in the back focal plane of a spherical spectacle lens improves as the front surface power increases and the refraction index decreases.

• Journal of Radiation Protection and Research
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• v.20 no.1
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• pp.25-36
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• 1995

The purpose of this research is to develop stereotactic localization and radiation measurement system for the efficient and precise radiosurgery. The algorithm to obtain a 3-D stereotactic coordinates of the target has been developed using a Fisher CT or angio localization. The procedure of stereotactic localization was programmed with PC computer, and consists of three steps: (1) transferring patient images into PC; (2) marking the position of target and reference points of the localizer from the patient image; (3) computing the stereotactic 3-D coordinates of target associated with position information of localizer. Coordinate transformation was quickly done on a real time base. The difference of coordinates computed from between Angio and CT localization method was within 2 mm, which could be generally accepted for the reliability of the localization system developed. We measured dose distribution in small fields of NEC 6 MVX linear accelerator using various detector; ion chamber, film, diode. Specific quantities measured include output factor, percent depth dose (PDD), tissue maximum ratio (TMR), off-axis ratio (OAR). There was small variation of measured data according to the different kinds of detectors used. The overall trends of measured beam data were similar enough to rely on our measurement. The measurement was performed with the use of hand-made spherical water phantom and film for standard arc set-up. We obtained the dose distribution as we expected. In conclusion, PC-based 3-D stereotactic localization system was developed to determine the stereotactic coordinate of the target. A convenient technique for the small field measurement was demonstrated. Those methods will be much helpful for the stereotactic radiosurgery.

• Korean Journal of Optics and Photonics
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• v.6 no.3
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• pp.188-200
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• 1995

A design of unit magnification 2-mirror system with high resolution is presented. It is for soft X-ray(wavelength of 13 nm) projection imaging and suitable for preparation of high density semiconductor chip. In general, a holosymmetric system with unit magnification has the advantage that both coma and distortion are completely eliminated. In our holosymmetric 2-mirror system, spherical aberration is addtionally removed by using two identical paraboloidal mirror surfaces and field curvature aberration is also corrected by balancing Petzval sum and astigmatism which depends on the distance between two mirrors, so that the system is a aplanatic flat-field paraboloidal 2-mirror holosymmetric system. This 2-mirror system is small in size, and has a simple configuration with rotational symmetry about optical axis, and has also small central obscuration. Residual finite aberrations, spot diagrams, and diffraction-based MTF's are analyzed for the check of performances as soft X-ray lithography projection system. As a result, the image sizes for the resolutions of$0.25\mum$and $0.18\mum$are 4.0 mm, 2.5 mm respectively, and depths of focus for those are $2.5\mum$, $2.4\mum$respectively. This system should be useful in the fabrication of 256 Mega DRAM or 1 Giga DRAM. DRAM.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.16 no.2
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• pp.165-172
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• 2018

As an approach for estimation of the droplet size in the molten salt-liquid metal extraction process, a droplet formation experiment at room temperature was conducted to evaluate the applicability of the Scheele-Meister model with water-mercury system as a surrogate that is similar to the molten salt-liquid metal system. In the experiment, droplets were formed through the nozzle and the droplet size was measured using a digital camera and image analysis software. As nozzles, commercially available needles with inner diameters (ID) of 0.018 cm and 0.025 cm and self-fabricated nozzles with 3-holes (ID: 0.0135 cm), 4-holes (ID: 0.0135 cm), and 2-holes (ID: 0.0148 cm) were used. The mercury penetration lengths in the nozzles were 1.3 cm for the needles and 0.5 cm for the self-fabricated nozzles. The droplets formed from each nozzle maintained stable spherical shape up to 20 cm below the nozzle. The droplet size measurements were within a 10% error range when compared to the Scheele-Meister model estimates. The experimental results show that the Scheele-Meister model for droplet size estimation can be applied to nozzles that stably form droplets in a water-mercury system.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.3D
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• pp.407-415
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• 2008

This study presents the methodology to link with aerial photos for advancing the accuracy of topographic survey data that is used to calculate water volume in urban stream. First, GIS spatial interpolation technique as Inverse Distance Weight (IDW) and Kriging was applied to construct the terrain morphology to the sand-bar and grass area using cross-sectional survey data, and also validation point data was used to estimate the accuracy of created topographic data. As the result of comparison, IDW ($d^{-2}_{ij}$, 2nd square number) in Sand-bar area and Kriging Spherical model in grass area showed more efficient results in the construction of topographic data of river boundary. But the differences among interpolation methods are very slight. Image classification method, Minimum Distance Method (MDM) was applied to extract sand-bar and grass area that are located to river boundary efficiently and the elevation value of extracted layers was allocated to the water level point value. Water volume with topographic data from aerial photos shows the advanced accuracy of 13% (in sand-bar) and 12% (in grass) compared to the water volume of original terrain data. Therefore, terrain analysis method in river linking with aerial photos is efficient to the monitoring about sand-bar and grass area that are located in the downstream of Dam in flooding season, and also it can be applied to calculate water volume efficiently.

• Progress in Medical Physics
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• v.27 no.2
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• pp.86-92
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• 2016

An absorbed dose calculation method using a digital phantom is implemented in normal organs. This method cannot be employed for calculating the absorbed dose of tumor. In this study, we measure the S-value for calculating the absorbed dose of each organ and tumor. We inject a radioisotope into a torso phantom and perform Monte Carlo simulation based on the CT data. The torso phantom has lung, liver, spinal, cylinder, and tumor simulated using a spherical phantom. The radioactivity of the actual absorbed dose is measured using the injected dose of the radioisotope, which is Cu-64 73.85 MBq, and detected using a glass dosimeter in the torso phantom. To perform the Monte Carlo simulation, the information on each organ and tumor acquired using the PET/CT and CT data provides anatomical information. The anatomical information is offered above mean value and manually segmented for each organ and tumor. The residence time of the radioisotope in each organ and tumor is calculated using the time activity curve of Cu-64 radioactivity. The S-values of each organ and tumor are calculated based on the Monte Carlo simulation data using the spatial coordinate, voxel size, and density information. The absorbed dose is evaluated using that obtained through the Monte Carlo simulation and the S-value and the residence time in each organ and tumor. The absorbed dose in liver, tumor1, and tumor2 is 4.52E-02, 4.61E-02, and 5.98E-02 mGy/MBq, respectively. The difference in the absorbed dose measured using the glass dosimeter and that obtained through the Monte Carlo simulation data is within 12.3%. The result of this study is that the absorbed dose obtained using an image can evaluate each difference region and size of a region of interest.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.4
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• pp.409-415
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• 2011

Purpose: To design applied anamorphic lens that focal length ratio is 3:1 optical system to improve detecting distance. Methods: We defined a boundary condition as $50^{\circ}{\sim}60^{\circ}$ for viewing angle, horizontal direction 36mm, vertical direction 12 mm for focal length, f-number 4, $15{\mu}m{\times}15{\mu}m$ for pixel size and limit resolution 25% in 33l p/mm. Si, ZnS and ZnSe as a materials were used and 4.8 ${\mu}m$, 4.2 ${\mu}m$, 3.7 ${\mu}m$ as a wavelength were set. optical performance with detection distance, narcissus and athermalization in designed camera were analyzed. Results: F-number 4, y direction 12 mm and x direction 36 mm for focal length of the thermal optical system were satisfied. Total length of the system was 76 mm so that an overall volume of the system was reduced. Astigmatism and spherical aberration was within ${\pm}$0.10 which was less than 2 pixel size. Distortion was within 10% so there was no matter to use as a thermal optical camera. MTF performance for the system was over 25% from 33l p/mm to full field so it was satisfied with the boundary condition. Designed optical system was able to detect up to 2.9 km and reduce a diffused image by decreasing a narcissus value from all surfaces except the 4th surface. From sensitivity analysis, MTF resolution was increased on changing temperature with the 5th lens which was assumed as compensation. Conclusions: Designed optical system which used anamorphic lens was satisfied with boundary condition. an increasing resolution with temperature, longer detecting distance and decreasing of narcissus were verified.

• The Journal of Korean Society for Radiation Therapy
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• v.22 no.2
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• pp.145-153
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• 2010

Purpose: To accurately define internal target volume (ITV) for treatment of moving target considering tumor size and respiratory motion, we quantitatively investigated volume of target volume delineated on CT images from helical CT and 4D CT scans. Materials and Methods: CT images for a 1D moving phantom with diameters of 1.5, 3, and 6 cm, acryl spheres were acquired using a LightSpeed $RT^{16}CT$ simulator. To analyze effect of tumor motion on target delineation, the CT image of the phantoms with various moving distances of 1~4 cm, and respiratory periods of 3~6 seconds, were acquired. For investigating the accuracy of the target trajectory, volume ratio of the target volumes delineated on CT images to expected volumes calculated with diameters of spherical phantom and moving distance were compared. Results: Ratio$_{helical}$ for the diameter of 1, 5, 3, and 6 cm targets were $32{\pm}14%$, $45{\pm}14%$, and $58{\pm}13%$, respectively, in the all cases. As to 4DCT, RatioMIP were $98{\pm}8%$, $97{\pm}5%$, and $95{\pm}1%$, respectively. Conclusion: The target volumes delineated on MIP images well represented the target trajectory, in comparison to those from helical CT. Target volume delineation on MIP images might be reasonable especially for treatment of early stage lung cancer, with meticulous attention to small size target, large respiratory motion, and fast breathing.