• 대한영상의학회지
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• 제82권5호
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• pp.1287-1291
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• 2021

고환 림프종은 무통성 종괴를 주소로 내원하는 드문 고환 종양이다. 일반적으로 고환 림프종은 칼라 도플러 초음파에서 고혈관성을 보이며, 컴퓨터단층촬영이나 자기공명영상에서 조영증강을 보인다. 저자들은 우측 고환 종대를 주소로 내원한 67세 환자에서 초음파 검사상 크기가 커진 고환 내 혈류가 보이지 않아 계류염전으로 진단하였으나, 전산화단층촬영에서는 주변부에 일부 조영증강을 보이는 종괴로 관찰되었고, 수술 이후 림프종이 진단된 증례를 경험하여 보고하고자 한다.

• Clinical and Experimental Reproductive Medicine
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• 제48권1호
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• pp.27-33
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• 2021

Objective: The chief outcome of testicular torsion in clinical and experimental contexts is testicular ischemia. Curcumin, a compound with anti-inflammatory and antioxidant properties, has fascinated researchers and clinicians for its promise in the treatment of fertility diseases. Methods: Thirty-five fully grown male mice were randomly classified into five groups: control, sham, testicular torsion, treatment group 1 (testicular torsion+short-term curcumin), and treatment group 2 (testicular torsion+long-term curcumin). Thirty-five days later, spermatozoa from the right cauda epididymis were analyzed with regard to count and motility. Toluidine blue (TB), aniline blue (AB), and chromomycin A3 (CMA3) staining assays were used to evaluate the sperm chromatin integrity. In addition, the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL) test was used to assess apoptosis. Results: Treatment group 1 exhibited a remarkably elevated sperm count compared to the testicular torsion group. Additionally, notably lower sperm motility was found in the testicular torsion group compared to the control, treatment 1, and treatment 2 groups. Staining (CMA3, AB, and TB) and the TUNEL test indicated significantly greater testicular torsion in the torsion group compared to the control group (p<0.05). The data also revealed notably lower results of all sperm chromatin assays and lower apoptosis in both treatment groups relative to the testicular torsion group (p<0.05). Significantly elevated (p<0.05) AB and TB results were noted in treatment group 1 compared to treatment group 2. Conclusion: Curcumin can compensate for the harmful effects of testicular ischemia and improve sperm chromatin quality in mice.