• Title/Summary/Keyword: Special component model

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Quantification of an active ingredient in tablets by NIR transmission measurements

  • Niemoller, Andreas;Schmidt, Angela;Weis, Aaron;Weiler, Helmut
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.4114-4114
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    • 2001
  • For the quality control of tablets several parameters have to be checked. The most important one is the content of an active ingredient which has to match a narrow range around the designated content. The only useful measurement mode is transmission which provides information of the complete tablet. A measurement in diffuse reflectance would register only the surface which is useless especially in case of a coated tablet. In this work tablets for a clinical study (placebo/verum studies) with very low concentrations of the active ingredient were measured. The concentration range was 0 to 6 mg with a total weight of the tablets of 105 mg, leading to a highest concentration of the active component of 5.7% by weight. Especially the spectroscopic distinction between the placebo and the low dosage forms with 0.25 and 0.5 mg active agent requires an extraordinarily accurate sampling technique. Using the VECTOR 22/N-T in transmission mode allows the collection of the information from the complete tablets. A quantitative PLS-model with transmission spectra from the tablets described above shows that the active substance can be predicted with a RMSECV (root mean square error of cross validation) of 0.04% absolute for this special application. The results are compared with those of measurements in diffuse reflectance using different accessories.

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Experimental studies on steel frame structures of traditional-style buildings

  • Xue, Jianyang;Qi, Liangjie
    • Steel and Composite Structures
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    • v.22 no.2
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    • pp.235-255
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    • 2016
  • This paper experimentally investigated the behavior of steel frame structures of traditional-style buildings subjected to combined constant axial load and reversed lateral cyclic loading conditions. The low cyclic reversed loading test was carried out on a 1/2 model of a traditional-style steel frame. The failure process and failure mode of the structure were observed. The mechanical behaviors of the steel frame, including hysteretic behaviors, order of plastic hinges, load-displacement curve, characteristic loads and corresponding displacements, ductility, energy dissipation capacity, and stiffness degradation were analyzed. Test results showed that the Dou-Gong component (a special construct in traditional-style buildings) in steel frame structures acted as the first seismic line under the action of horizontal loads, the plastic hinges at the beam end developed sufficiently and satisfied the Chinese Seismic Design Principle of "strong columns-weak beams, strong joints-weak members". The pinching phenomenon of hysteretic loops occurred and it changed into Z-shape, indicating shear-slip property. The stiffness degradation of the structure was significant at the early stage of the loading. When failure, the ultimate elastic-plastic interlayer displacement angle was 1/20, which indicated high collapse resistance capacity of the steel frame. Furthermore, the finite element analysis was conducted to simulate the behavior of traditional-style frame structure. Test results agreed well with the results of the finite element analysis.

Prediction of Land-cover Change Based on Climate Change Scenarios and Regional Characteristics using Cluster Analysis (기후변화 시나리오에 따른 미래 토지피복변화 예측 및 군집분석을 이용한 지역 특성 분석)

  • Oh, Yun-Gyeong;Choi, Jin-Yong;Yoo, Seung-Hwan;Lee, Sang-Hyun
    • Journal of The Korean Society of Agricultural Engineers
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    • v.53 no.6
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    • pp.31-41
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    • 2011
  • This study was conducted to predict future land-cover changes under climate change scenarios and to cluster analysis of regional land-cover characteristics. To simulate the future land-cover according to climate change scenarios - A1B, A2, and B1 of the Special Report on Emissions Scenarios (SRES), Dyna-CLUE (Conversion of Land Use Change and its Effects) was applied for modeling of competition among land-use types in relation with socioeconomic and biophysical driving factors. Gyeonggi-do were selected as study areas. The simulation results from 2010 to 2040 suggested future land-cover changes under the scenario conditions. All scenarios resulted in a gradual decrease in paddy area, while upland area continuously increased. A1B scenario showed the highest increase in built-up area, but all scenarios showed only slight changes in forest area. As a result of cluster analysis with the land-cover component scores, 31 si/gun in Gyeonggi-do were classified into three clusters. This approach is expected to be useful for evaluating and simulating land-use changes in relation to development constraints and scenarios. The results could be used as fundamental basis for providing policy direction by considering regional land-cover characteristics.

The Practical Application of Bluetooth Media Technology and Outlook for Development

  • Song, Zheng-Hua;Shin, Hyun-Sik;Kim, Chun-Suk;Shin, Yun-Ho
    • The Journal of the Korea institute of electronic communication sciences
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    • v.1 no.1
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    • pp.87-93
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    • 2006
  • This is paper, with the development of computer and network communications technology, the technology of digital computer and modern communications has integrated into the field of intelligent home appliances, making them intelligentize with the function of a network information terminal. The paper introduces the Bluetooth SIG(Special Interesting Group) and the development of the standard of the Bluetooth. Researches the application model and the practical application of the Bluetooth technology, and the component elements of the Bluetooth. Finally deals with the outlook for the development of the Bluetooth technology.

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Formation of Scenarios for The Development of The Tourism Industry of Ukraine With The Help of Cognitive Modeling

  • Shelemetieva, Tetiana;Zatsepina, Nataly;Barna, Marta;Topornytska, Mariia;Tuchkovska, Iryna
    • International Journal of Computer Science & Network Security
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    • v.21 no.7
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    • pp.8-16
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    • 2021
  • The tourism industry is influenced by a large number of factors that affect the development scenarios of the tourism in different ways. At the same time, tourism is an important component of the national economy of any state, forms its image, investment attractiveness, is a source of income and a stimulus for business development. The aim of the article is to conduct an empirical study to identify the importance of cognitive determinants in the development of tourism. The study used general and special methods: systems analysis, synthesis, grouping, systematization, cognitive modeling, cognitive map, pulse method, predictive extrapolation. Target factors, indicators, and control factors influencing the development of tourism in Ukraine are determined and a cognitive model is built, which graphically reflects the nature of the influence of these factors. Four main scenarios of the Ukrainian tourism industry are established on the basis of creating a matrix of adjacency of an oriented graph and forecast modeling based on a scenario approach. The practical significance of the obtained results lies in the possibility of their use to forecast the prospects of tourism development in Ukraine, the definition of state policy to support the industry that will promote international and domestic tourism.

Research on Performance Evaluation of Listed Logistics Enterprises in China (중국 물류 상장기업의 성과평가에 관한 연구)

  • Lingfeng Wang;Jae-Yeon Sim
    • Industry Promotion Research
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    • v.8 no.2
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    • pp.177-185
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    • 2023
  • Logistics companies have rapidly developed as an important component of economic activities, but due to the special performance management method of logistics companies, problems in performance evaluation are emerging. This paper presented a strategy for improving performance by analyzing the management performance of 19 listed logistics companies in China. Operating expenses, R&D expenses, labor costs, and general management expenses were adopted as input variables, and operating profit and net profit were adopted as output variables. DEA efficiency was assessed by the BBC model from 2016 to 2021 using DEAP 2.1 software. As a result of analyzing the annual management performance, some listed logistics companies showed stable and forward-looking performance results.

A Development of Query-Answer Learning Tool based on LTSA (LTSA 기반의 질의 응답 학습 도구 개발)

  • Kim, Haeng-Kon;Kim, Jung-Soo
    • The KIPS Transactions:PartA
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    • v.10A no.3
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    • pp.269-278
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    • 2003
  • The popularity of the web based education has come the need for variety learning methods and for business to exploit the web not only for interoperability but also standardization. This way of standardization has come to researched for environments, contents and practical uses in ISO. The IEEE has special]y established five technical classes for LTSA which provide advanced e-learning environments. Feedback functions would not be supported and specified in standardization for Query Answer on LTSA. In this paper, we describe the query and answer model which we have developed on layer three of LTSA. We develop the redefined model for transforming data flow oriented into object or component based model. We have developed the Query Answer Metadata (QAM) based on Learning Object Metadata (LOM). We design and showed thing a prototyping implementation the Query Answer Learning Tool (QALT). We have used the QALT to address the problem of efficiency of web based education. We also used it to develop the related tools with quality and productivity.

Experimental study on standard and innovative bolted end-plate beam-to-beam joints under bending

  • Katula, Levente;Dunai, Laszlo
    • Steel and Composite Structures
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    • v.18 no.6
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    • pp.1423-1450
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    • 2015
  • The paper presents the details and results of an experimental study on bolted end-plate joints of industrial type steel building frames. The investigated joints are commonly used in Lindab-Astron industrial buildings and are optimized for manufacturing, erection and durability. The aim of the research was to provide an experimental background for the design model development by studying load-bearing capacity of joints, bolt force distribution, and end-plate deformations. Because of the special joint details, (i.e., joints with four bolts in one bolt-row and HammerHead arrangements), the Eurocode 3 standardized component model had to be improved and extended. The experimental programme included six different end-plate and bolt arrangements and covered sixteen specimens. The steel grade of test specimens was S355, the bolt diameter M20, whereas the bolt grade was 8.8 and 10.9 for the two series. The end-plate thickness varied between 12 mm and 24 mm. The specimens were investigated under pure bending conditions using a four-point-bending test arrangement. In all tests the typical displacements and the bolt force distribution were measured. The end-plate plastic deformations were measured after the tests by an automatic measuring device. The measured data were presented and evaluated by the moment-bolt-row force and moment-distance from centre of compression diagrams and by the deformed end-plate surfaces. From the results the typical failure modes and the joint behaviour were specified and presented. Furthermore the influence of the end-plate thickness and the pretension of the bolts on the behaviour of bolted joints were analysed.

A 3-D RBSM for simulating the failure process of RC structures

  • Zhong, Xingu;Zhao, Chao;Liu, Bo;Shu, Xiaojuan;Shen, Mingyan
    • Structural Engineering and Mechanics
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    • v.65 no.3
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    • pp.291-302
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    • 2018
  • Rigid body spring method (RBSM) is an effective tool to simulate the cracking process of structures, and has been successfully applied to investigate the behavior of reinforced concrete (RC) members. However, the theoretical researches and engineering applications of this method mainly focus on two-dimensional problems as yet, which greatly limits its applications in actual engineering projects. In this study, a three-dimensional (3-D) RBSM for RC structures is proposed. In the proposed model, concrete, reinforcing steels, and their interfaces are represented as discrete entities. Concrete is partitioned into a collection of rigid blocks and a uniform distribution of normal and tangential springs is defined along their boundaries to reflect its material properties. Reinforcement is modeled as a series of bar elements which can be freely positioned in the structural domain and irrespective of the mesh geometry of concrete. The bond-slip characteristics between reinforcing steel and concrete are also considered by introducing special linkage elements. The applicability and effectiveness of the proposed method is firstly confirmed by an elastic T-shape beam, and then it is applied to analyze the failure processes of a Z-type component under direct shear loading and a RC beam under two-point loading.

Plant-wide On-line Monitoring and Diagnosis Based on Hierarchical Decomposition and Principal Component Analysis (계층적 분해 방법과 PCA를 이용한 공장규모 실시간 감시 및 진단)

  • Cho Hyun-Woo;Han Chong-hun
    • Journal of the Korean Institute of Gas
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    • v.1 no.1
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    • pp.27-32
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    • 1997
  • Continual monitoring of abnormal operating conditions i a key issue in maintaining high product quality and safe operation, since the undetected process abnormality may lead to the undesirable operations, finally producing low quality products, or breakdown of equipment. The statistical projection method recently highlighted has the advantage of easily building reference model with the historical measurement data in the statistically in-control state and not requiring any detailed mathematical model or knowledge-base of process. As the complexity of process increases, however, we have more measurement variables and recycle streams. This situation may not only result in the frequent occurrence of process Perturbation, but make it difficult to pinpoint trouble-making causes or at most assignable source unit due to the confusing candidates. Consequently, an ad hoc skill to monitor and diagnose in plat-wide scale is needed. In this paper, we propose a hierarchical plant-wide monitoring methodology based on hierarchical decomposition and principal component analysis for handling the complexity and interactions among process units. This have the effect of preventing special events in a specific sub-block from propagating to other sub-blocks or at least delaying the transfer of undesired state, and so make it possible to quickly detect and diagnose the process malfunctions. To prove the performance of the proposed methodology, we simulate the Tennessee Eastman benchmark process which is operated continuously with 41 measurement variables of five major units. Simulation results have shown that the proposed methodology offers a fast and reliable monitoring and diagnosis for a large scale chemical plant.

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