• Title/Summary/Keyword: Spearman coefficient

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Correlation Between Apoptosis and Intratumoral Microvessel Density in Non-Small Cell Lung Cancer. (비소세포 폐암에서 아포프토시스와 종양내 미세 혈관 밀도의 관계)

  • 장인석;김종우;김진국;한정호
    • Journal of Chest Surgery
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    • v.32 no.2
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    • pp.151-157
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    • 1999
  • Background: Increasing evidences from experimental studies indicate that apoptosis may be inversely related to angiogenesis in tumor progression. Material and Method: To explore how apoptosis correlates with tumor angiogenesis, we measured the apoptotic index(AI) using the terminal deoxynucleotidyl transferase method(Apop Tag In Situ Apoptosis Detection Kit, ONCOR) and the intratumoral microvessel density using the anti-CD31 monoclonal antibody in non-small cell lung cancer. Result: Statistical analysis revealed an inverse correlation between AIs and intratumoral microvessel densities in squamous cell lung carcinoma(Spearman rank correlation coefficient r=- 0.229, p=0.047). Conclusion: The results of this study demonstrated that the amount of apoptosis in squamous cell lung carcinoma may be influenced by the extent of neovascularization. This suggests that tumor angiogenesis may contribute to a reduction of apoptosis in tumor cells.

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Characterization and Assessment of Indoor Air Quality in Newly Constructed Apartments -Volatile Organic Compounds and Formaldehyde- (신축공동주택의 실내공기질 특성 및 평가 -휘발성 유기화합물 및 포름알데히드 중심으로-)

  • Sim, Sang-Hyo;Kim, Yoon-Shin
    • Journal of Environmental Health Sciences
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    • v.32 no.4 s.91
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    • pp.275-281
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    • 2006
  • Indoor air quality is the dominant contributor to total personal exposure because most people spend a majority of their time indoors. Especially exposure to indoor air can potentially pose a greater threat than exposure to ambient air when indoor environments have sources of contaminants. In this study, volatile organic compounds (VOCs) and formaldehyde (HCHO) within newly constructed apartment have been determined in 27 houses of apartment in Seoul from December 2004 to March 2005. The measured indoor air pollutants were HCHO, volatile organic compounds including benzene, toluene, styrene, xylene, ethylbenzene and sampled on the standard method of Ministry of Environment in Korea. The indoor levels for benzene, xylene, toluene, ethylbenzene, styrene, and HCHO have significant increase trend after 5 hours closing of windows and doors. Levels of measured air pollutants concentrations between living rooms and bedrooms have not shown significant difference. Spearman correlation coefficient among the measured air pollutants ranged from 0.303 to 0.946, indicating similar source in building materials.

Standardized Uptake Values Highly Correlate with Tumor Size and Fuhrman Grade in Patients with Clear Cell Renal Cell Carcinoma

  • Polat, Emre Can;Otunctemur, Alper;Ozbek, Emin;Besiroglu, Huseyin;Dursun, Murat;Ozer, Kutan;Horsanali, Mustafa Ozan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.18
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    • pp.7821-7824
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    • 2014
  • Background: We investigated the correlation between standardized uptake value (SUVmax), tumor size and Fuhrman grade in patients with renal cell carcinoma (RC). Materials and Methods: We retrospectively analyzed the data of 54 patients with clear cell renal cell carcinoma histopathologically diagnosed who underwent fluorine-18 fluoro-2 deoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) between January 2005 and March 2014. Results: Avarage tumor sizes were $5.64{\pm}1.85$, $6.85{\pm}2.24$ and $7.98{\pm}2.45$ in low, medium and high SUVmax groups, respectively. The Spearman's correlation coefficient between the tumor size and SUVmax was 0.385 (p=0.004) and between the Fuhrman grade and SUVmax was 0.578 (p<0.001). Conclusions: SUVmax appears highly correlated with tumor size and Fuhrman grade in patients with histopathologically confirmed clear cell RC. Multicenter studies are needed to provide larger series for more accurate results.

Probabilistic Design under Uncertainty using Response Surface Methodology and Pearson System (반응표면방법론과 피어슨 시스템을 이용한 불확실성하의 확률적 설계)

  • Baek Seok-Heum;Cho Soek-Swoo;Joo Won-Sik
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2006.04a
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    • pp.275-282
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    • 2006
  • System algorithms estimated by deterministic input may occur the error between predicted and actual output. Especially, actual system can't predict the exact outputs due to uncertainty and tolernce of input parameters. A single output to a set of inputs has a limited value without the variation. Hence, we should consider various scatters caused by the load assessment, material characteristics, stress analysis and manufacturing methods in order to perform the robust design or etimate the reliability of structure. The system design with uncertainty should perform the probabilistic structural optimization with the statistical response and the reliability. This method calculated the probability distributions of the characteristics such as stress by combining stress analysis, response surface methodology and Monte Carlo simulation and got the probabilistic sensitivity. The sensitivity of structural response with respect to in constant design variables was estimated by fracture probability. Therefore, this paper proposed the probabilistic reliability design method for fracture of uncorved freight end beam and the design criteria by fracture probability.

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Regression Trees with. Unbiased Variable Selection (변수선택 편향이 없는 회귀나무를 만들기 위한 알고리즘)

  • 김진흠;김민호
    • The Korean Journal of Applied Statistics
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    • v.17 no.3
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    • pp.459-473
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    • 2004
  • It has well known that an exhaustive search algorithm suggested by Breiman et. a1.(1984) has a trend to select the variable having relatively many possible splits as an splitting rule. We propose an algorithm to overcome this variable selection bias problem and then construct unbiased regression trees based on the algorithm. The proposed algorithm runs two steps of selecting a split variable and determining a split rule for binary split based on the split variable. Simulation studies were performed to compare the proposed algorithm with Breiman et a1.(1984)'s CART(Classification and Regression Tree) in terms of degree of variable selection bias, variable selection power, and MSE(Mean Squared Error). Also, we illustrate the proposed algorithm with real data sets.

Distributions of the GSTM1 and GSTT1 Null Genotypes Worldwide are Characterized by Latitudinal Clines

  • Saitou, Marie;Ishida, Takafumi
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.355-361
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    • 2015
  • Background: Deletion types of genetic variants of glutathione S-transferase (GST) M1 and T1, the GSTM1 null and GSTT1 null which are risk factors for certain cancers, have been ubiquitously found in human populations but their worldwide distribution pattern is unclear. Materials and Methods: To perform a meta-analysis, a systematic search for the literature on GSTM1 and GSTT1 null genotypes was done to identify 63 reports for 81 human populations. Relationships between the GSTM1 and GSTT1 null genotype frequencies and the absolute latitude of 81 populations were tested by Spearman's rank correlation coefficient. Results: A significant positive correlation was detected between the GSTM1 null genotype frequency and the absolute latitude (r=0.28, p-value <0.05), whereas the GSTT1 null genotype frequency and absolute latitude showed a significant negative correlation (r= -0.41 p-value <0.01). There was no correlation between the frequencies of GSTM1 and GSTT1 null genotype in each population (r= -0.029, p-value=0.80). Conclusions: Latitudinal clines of the distribution of the GSTM1 and GSTT1 null genotypes may be attributed to the result of gene-environmental adaptation. No functional compensation between GSTM1 and GSTT1 was suggested by the lack of correlation between the null frequencies for GSTM1 and GSTT1.

The Relationship between Eating disorder and Self-esteen in Female College Students (여자대학생들의 섭식장애와 자아존중감과의 관계)

  • Lee, Kyung-Hye;Kim, Sook-Kyung;Chun, Ki-Jeong;Han, Sook-Hee
    • Women's Health Nursing
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    • v.9 no.4
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    • pp.390-399
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    • 2003
  • Purpose: The purpose of this study was to investigate the relationship between eating disorders, and self esteem in female college students. Method: The survey was carried out on convenience sample of 388 college female students. The questionnaire consisted of each scale for eating disorder, self-esteem. The data was analyzed by the SPSS/PC using frequency, percentage, mean, standard deviation. ANOVA, and Spearman correlation. coefficient. Result: More than 43% of the subjects perceived their weight as overweight, while 1.5% of the women were obese as defined by BMI. About 57.4% of subjects were not satisfied with their body shape. Frequency of eating disorder was 5.93%. The score of eating disorder was high when the subjecto had negative perception and low satisfaction with their body shape. The high scores of self-esteem were shown among the group who had high satisfaction on body shape. There was negative correlation between eating disorder and self-esteem (r=-.194, p=.000). Conclusion: This study suggests that the nursing intervention was necessary for female college students to recognize healthier eating habits and increased their self-esteem.

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Visual Fatigue Prediction for Stereoscopic Video Considering Individual Fusional Characteristics (시청자의 입체시 특성을 고려한 3D 비디오의 피로도 예측)

  • Kim, Dong-Hyun;Choi, Sung-Hwan;Sohn, Kwang-Hoon
    • Journal of Broadcast Engineering
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    • v.16 no.2
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    • pp.331-338
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    • 2011
  • In this paper, we propose a visual fatigue prediction metric which considers individual fusional characteristics for stereoscopic video. It predicts the visual fatigue level by examining the disparity and motion characteristics of 3D videos. In addition, we classified the viewers into 2 groups according to fusional limit and the slope of fusional response which are acquired from random dot stereogram test. Then, Pearson's and Spearman's correlation coefficient was measured between the proposed metrics and the subjective results, acquiring 80% and 79%.

Effects of Postural Habits and Stress on Low Back Pain in Nursing Students (생활습관자세 및 스트레스가 간호대학생의 요통에 미치는 영향)

  • Kim, Jisoo;Choi, Jeong-Sil
    • Journal of muscle and joint health
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    • v.21 no.3
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    • pp.165-172
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    • 2014
  • Purpose: The purpose of this study was to identify effects of postural habits and stress on low back pain experienced by nursing students. Methods: The survey was conducted with 282 students at 5 nursing schools in Seoul, Incheon, Chungcheongbuk, and Jeollabuk Province. Data were collected from October, 2013 to January, 2014. Data analyses including descriptive analysis, ANOVA, Pearson's correlation coefficient, Spearman's rank correlation coefficients, and multiple regression were performed using SPSS 21.0. Results: In multiple regression, habit of standing on force of one feet (${\beta}=.23$, p<.001), habit of sleeping on one's back (${\beta}=-.19$, p=.020), habit of resting the chin on one's hands (${\beta}=.15$, p=.029), and habit of carrying a bag on one shoulder (${\beta}=.12$, p=.011) were associated with low back pain experienced by nursing students. These factors accounted for 12.9% of the variance in the low back pain in undergraduate students. Conclusion: These results suggest that low back pain in nursing students are related to their habits of posture in daily life. Therefore, intervention program to encourage healthy postural habits can be effective to prevent low back pain in nursing students.

Meiobenthos in Estuary Part of Ha Long Bay (Gulf of Tonkin, South China Sea, Vietnam)

  • Pavlyuk, Olga;Trebukhova, Yulia;Thanh, Nguyen Vu;Tu, Nguyen Dinh
    • Ocean Science Journal
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    • v.43 no.3
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    • pp.153-160
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    • 2008
  • The distribution of the taxonomical composition and the density of meiobenthos depending on some factors of environment has been studied in bottom sediments of the northern estuary part of Ha Long Bay (Cua Luc estuary). The basic factor of influence on meiobenthic community structure was the granulometric composition of sediment. The greatest taxonomic diversity is noted in the silted sands, lowest - in the silty sediments. The density of meiobenthic community was higher in the silty sediments. Slightly expressed correlation between the density of nematodes and the percentage of silty particles in the sediments is detected (Spearman rank correlation coefficient was $0.49{\pm}0.21$, p=0.035). The nematodes were dominant at all stations. In total, representatives of 66 species of nematodes belonging to 17 families and 52 genera were identified.