• 제목/요약/키워드: Spatial Development

검색결과 4,059건 처리시간 0.03초

CTCF, Cohesin, and Chromatin in Human Cancer

  • Song, Sang-Hyun;Kim, Tae-You
    • Genomics & Informatics
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    • 제15권4호
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    • pp.114-122
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    • 2017
  • It is becoming increasingly clear that eukaryotic genomes are subjected to higher-order chromatin organization by the CCCTC-binding factor/cohesin complex. Their dynamic interactions in three dimensions within the nucleus regulate gene transcription by changing the chromatin architecture. Such spatial genomic organization is functionally important for the spatial disposition of chromosomes to control cell fate during development and differentiation. Thus, the dysregulation of proper long-range chromatin interactions may influence the development of tumorigenesis and cancer progression.

수변구역 토지정보관리시스템 구축

  • 윤천주;김계현
    • 한국GIS학회:학술대회논문집
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    • 한국GIS학회 2002년도 춘계학술대회논문집
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    • pp.153-159
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    • 2002
  • This study mainly concentrates on the development of a land information management system to manage the land related information in an effective way for the water-pollutant buffering zone, which was established to sustain better quality of the drinking water over the upper part of the Han river. For developing such system, a procedure was implemented covering user requirement analysis, system design, spatial DB design, and coding. DB linkage with affiliated institutes and cadastral DB updating were proposed as the part of the efforts to enhance the applicability of the system. In addition to that, modularization was adopted for more efficient and cost-effective system development.

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해양공간계획(MSP)제도 도입의 필요성에 관한 연구 (A Study on the Necessity of Introducing Marine Spatial Planning in Korea)

  • 채동렬
    • 해양환경안전학회지
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    • 제15권3호
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    • pp.237-242
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    • 2009
  • 최근 육상부존자원의 한계봉착과 신물질개발 및 국제 물류 이동의 증가 등으로 인하여 해양개발수요가 증가하고 있다. 해양에서의 개발행위는 해양생물과 그 서식지에 외부불경제를 유발한다. 이러한 보호와 개발간의 대립을 극복하고 지속가능한 해양이용을 추구하기 위해 고안된 제도가 해양공간계획이다. 본 논문은 해양공간 계획제도가 가지는 효과를 경제적, 생태적, 정책적 측면으로 구분하여 분석하였으며, 우리나라에서 해양공간계획제도의 도입이 필요한 이유를 설명하고 해양공간계획 제도의 성공을 위한 전제조건을 제시하였다.

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국내 해상풍력 발전단지 입지 분석 연구 (Study of the Spatial Location Analysis for Domestic Offshore Wind Farm)

  • 김동휘;이용준;류인호;서대림
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2010년도 추계 학술발표회
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    • pp.504-511
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    • 2010
  • After facing the fact such as fossil-fuel depletion, global warming, the Kyoto Protocol coming into force of mandatory reductions of carbon dioxide, the world is actively promoting the spread of the solar, wind, tidal, geothermal and other clean renewable energy technology development. Among them, wind power is the only alternative energy to secure a comparable price competition with fossil fuels because cheaper price power generation than other renewable energy when creating large-scale wind farm, thus wind power is the fastest growing industries in the world in the renewable energy field. Especially the offshore wind power is showing rapid growth as most of the wind power sector because of less changes of wind speed, no restrictions of land use, and large-scale development of offshore wind power. In this paper, the field of site selection and spatial location analysis techniques for development of large-scale offshore wind farm are discussed primarily. This paper shows overview of offshore wind power and establishment procedure for development of offshore wind farm.

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Single-cell and spatial transcriptomics approaches of cardiovascular development and disease

  • Roth, Robert;Kim, Soochi;Kim, Jeesu;Rhee, Siyeon
    • BMB Reports
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    • 제53권8호
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    • pp.393-399
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    • 2020
  • Recent advancements in the resolution and throughput of single-cell analyses, including single-cell RNA sequencing (scRNA-seq), have achieved significant progress in biomedical research in the last decade. These techniques have been used to understand cellular heterogeneity by identifying many rare and novel cell types and characterizing subpopulations of cells that make up organs and tissues. Analysis across various datasets can elucidate temporal patterning in gene expression and developmental cues and is also employed to examine the response of cells to acute injury, damage, or disruption. Specifically, scRNA-seq and spatially resolved transcriptomics have been used to describe the identity of novel or rare cell subpopulations and transcriptional variations that are related to normal and pathological conditions in mammalian models and human tissues. These applications have critically contributed to advance basic cardiovascular research in the past decade by identifying novel cell types implicated in development and disease. In this review, we describe current scRNA-seq technologies and how current scRNA-seq and spatial transcriptomic (ST) techniques have advanced our understanding of cardiovascular development and disease.

농촌계획 관점에서 본 국토계획법의 개선방안 (A Discussion on the National Land Planning and Use Act from the Rural Planning of View)

  • 황한철
    • 농촌계획
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    • 제10권2호
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    • pp.51-60
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    • 2004
  • Through the fast economic growth since the 1960s, Korea has experienced various problems on land such as urban sprawl, the rapid increase in land prices, land speculation, privatization of the betterment, and so on. To prevent such problems and to enhance harmonious development and conservation, the National Land Planning and Use Act(NLPUA) was established in 2003. The NLPUA which was revised and combined two existing planning laws i.e. the National Land Use Management Act and Urban Planning Act, has an eye to preventing disorderly spatial development, to pursuing environmentally friendly spatial planning, and to following up planned development in non-urbanized area like rural area. This study aims to discuss what should be considered the pending issues after the application of the NLPUA in rural area. On the basis of reviewing the NLPUA in a viewpoint of the rural planning, this study suggests some improvement policy such as considering various rural conditions, securing excellent agricultural land, applying the District Plan II system effectively, reorganizing the planning administrative, and so on.

What Kinds of Lands Have Been Converted into the Urban Uses?: the Characteristics of Urban Land Development in the Case of Daegu Region

  • Kim, Jae-Ik
    • 토지주택연구
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    • 제3권2호
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    • pp.111-116
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    • 2012
  • The primary purposes of this study are to identify the characteristics of land development in urban area through GIS and remote sensing techniques and to provide useful implications for urban spatial policy. To perform these tasks, Daegu metropolitan city and its vicinities were selected as a study area, and remote sensing data and attributed data were collected, organized and analyzed. This study focuses on the following three steps. First, it identifies the characteristics of land development in urban areas by utilizing multi-temporal satellite image data (Landsat TM, 1980, 1985, 1990, 1995, 2000 and 2005). Second, it tries to find an answer on a critical question concerning land use conversion, i.e., which land use leads expansion of urban area? Third, it derives implications for urban spatial policies based on these findings. The characteristics of the urban extents tell us that the main land use converted into urban use from non-urban uses is green areas. The public sector, central and local governments, leads the land use conversions of suburban lands as exclusive legal body to issue permission of land use change. Based on these findings, this study concludes that the more systematic and technically advanced management tools should be utilized for more effective spatial management for urban growth.

GSIS를 이용한 입지선정에 있어 퍼지공간중첩기법의 적용에 관한 연구 (The application of fuzzy spatial overlay method to the site selection using GSIS)

  • 임승현;조기성
    • 한국측량학회지
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    • 제17권2호
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    • pp.177-187
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    • 1999
  • 현재까지 GSIS를 이용하는 많은 응용분야에서 각종 공간자료의 추출 및 분석을 위해 벡터형 공간중첩(spatial overay)이나 격자형 공간연산(spatial algebra)기능이 주로 사용되었다. 하지만 이런 방법에 내재하고 있는 개념은 전통적인 보통집합이론에 근거하고 있기 때문에 많은 종류의 공간자료들이 구간설정에 있어서 예리한 경계로 분할되는 것으로 다루어지고 있다. 이것은 현실 세계에 존재하는 실제 자료들의 공간분포패턴과 일치하지 않는다. 즉, 공간상에 일정영역이나 실체들이 오직 한가지 속성으로 한정되는(one-entity-one-value)오류를 그대로 포함하고 있다. 본 연구는 이러한 보통집합의 개념하에서 공간자료를 다루어 왔던 종래의 방식을 개선하기 위해서 공간자료가 지니는 모호함 내지 경계의 애매성을 잘 표현할 수 있는 퍼지집합의 개념을 두 가지 방법을 통해 공간중첩과정에 도입하였다. 첫 번째 방법은 공간적으로 연속성을 갖는 자료에 대해서 퍼지부분집합에 의한 퍼지구간분할법이며, 두 번째 방법은 범주형 자료에 대해서 적용한 퍼지경계집합법이다. 사례연구로서 신시가지 개발입지선정을 위한 적지분석을 수행을 함으로서 기존의 부울분석방법과 퍼지 공간 중첩법의 결과를 비교하였으며 그 결과, 퍼지공간중첩법에 의한 적합도면이 신시가지 개발입지에 대한 보다 타당성 있는 정보를 제공하며, 더불어 정보표현측면에서도 더욱 적절한 형태임을 알 수 있었다.

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