• Archives of Pharmacal Research
• /
• v.12 no.2
• /
• pp.79-87
• /
• 1989

Enzymatic methylation of arginine and lysine residues of several cytochrome c and lysine residue of calmodulin always resulted in lowering of their respective isoelectric points (pI). Employing cytochromes c derived from various sources, we examined a possible relationship between the degree of amino acid sequence degeneracy and the magnitude of change in the pI values by enzymatic methylation, and found that there was no correlation between these two parameters. By constructing space-filling models of oligopeptide fragments adjacent to the potential methylation sites, we have noted that not all the methylatable residues are able to form hydrogen bonds prior to the methylation. Two preparations of yeast apocytochrome c, one chemically prepared by removing heme from holocytochrome c and the other by translating yeast iso-1-cytochrome c mRNA in vitro, exhibited slightly higher Stokes radii than the homologous holocytochrome c, indicating relatively 'relaxed or open' conformation of the protein. However, when the in vitro synthesized methylated apocytochrome c was compared with the unmethylated counter-part, the Stokes radius of the latter was found to be larger.

• Journal of Korean Medical classics
• /
• v.22 no.1
• /
• pp.15-26
• /
• 2009

Seonya theory(宣夜說) was one of the most important metagalaxy model in the ancient times. Unlike the other important metagalaxy model, it had the concept that the sky is not in the solid state but is just the infinite space which is full of gi(氣). But Seonya theory, though it had partially the superb academic thought, it had gradually become the forgotten thing among scholars in the ancient times. Since then, once forgotten Seonya theory was reconstructed again in Song(宋) dynasty, and Jangjae(張載) did the main role at that time. In the historical sequence like this, we need to take notice of one thing that "Hwangjenaegyeong(黃帝內經)" had worked on Jangjae as the origin of his sunya theory. So we also need to take notice of one thing that "Hwangjenaegyeong" is just a rare document that comprises the academic thought of Seonya theory which had once been forgotten in ancient times. Based on the historical situation like this, this study is focused on the idea that the discuss on the Jangjae's Seonya theory would be a good way to think of the cosmic theory of "Hwangjenaegyeong" and the theoretical thought derived from them. So this study will first look into the academic characteristics of Seonya theory of ancient times and of "Hwangjenaegyeong" and through the study on the academic characteristics of Jangjae(張載)'s Seonya theory, will also think of the significance of the thought of Jangjae's Seonya theory that would be some help to the research on "Hwangjenaegyeong".

• Journal of Positioning, Navigation, and Timing
• /
• v.4 no.4
• /
• pp.161-171
• /
• 2015

Alternative binary offset carrier (AltBOC) signals can be approximated by four synchronized direct sequence spread spectrum (DSSS) signals, each pair of which is a quadrature phase shift keyed (QPSK) signal at a different frequency. Therefore, depending on the strength of an incoming AltBOC signal, an acquisition technique can reduce the mean acquisition time (MAT) by searching the four DSSS signals asynchronously; the search for each of the four DSSS signals can start at one of the evenly separated hypotheses on the two-dimensional hypothesis space. And detection sensitivity can be improved by multiple levels when different numbers of search results for the same hypothesis are combined. In this paper, we propose a fast AltBOC acquisition technique that has an asynchronous search strategy and efficiently utilizes the output of the four search results to increase the sensitivity level when sensitivity improvement is needed. We provide a complete theoretical analysis and demonstrate with numerous Monte Carlo simulations that the MAT of the proposed technique is much smaller than conventional AltBOC acquisition techniques.

• ETRI Journal
• /
• v.32 no.6
• /
• pp.871-880
• /
• 2010

Many applications dealing with image management need a technique for removing duplicate images or for grouping related (near-duplicate) images in a database. This paper proposes a concentric circle-based image signature which makes it possible to detect near-duplicates rapidly and accurately. An image is partitioned by radius and angle levels from the center of the image. Feature values are calculated using the average or variation between the partitioned sub-regions. The feature values distributed in sequence are formed into an image signature by hash generation. The hashing facilitates storage space reduction and fast matching. The performance was evaluated through discriminability and robustness tests. Using these tests, the particularity among the different images and the invariability among the modified images are verified, respectively. In addition, we also measured the discriminability and robustness by the distribution analysis of the hashed bits. The proposed method is robust to various modifications, as shown by its average detection rate of 98.99%. The experimental results showed that the proposed method is suitable for near-duplicate detection in large databases.

• ETRI Journal
• /
• v.40 no.3
• /
• pp.309-317
• /
• 2018

Single carrier-frequency-division multiple access (SC-FDMA) has been adopted as the uplink transmission standard in fourth-generation cellular networks to facilitate power efficiency transmission in mobile stations. Because multiuser multiple-input multiple-output (MU-MIMO) is a promising technology employed to fully exploit the channel capacity in mobile radio networks, this study investigates the uplink transmission of MU-MIMO SC-FDMA systems with orthogonal space-frequency block codes (SFBCs). It is preferable to minimize the length of the cyclic prefix (CP). In this study, the chained turbo equalization technique with chained turbo estimation is employed in the designed receiver. Chained turbo estimation employs a short training sequence to improve the spectrum efficiency without compromising the estimation accuracy. In this paper, we propose a novel and spectrally efficient iterative joint-channel estimation, multiuser detection, and turbo equalization for an MU-MIMO SC-FDMA system without CP-insertion and with short TR. Some simulation examples are presented for the uplink scenario to demonstrate the effectiveness of the proposed scheme.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.24 no.4 s.175
• /
• pp.848-857
• /
• 2000

A pick-and-place operation in 3-dimensional environment is basic operation for human and multi-purpose manipulators. However, there may be a difficult problem for such manipulators. Especially, if the object cannot be moved with a single grasp, regrasping, which can be a time-consuming process, should be carried out. Regrasping, given initial and final pose of the target object, is a construction of sequential transition of object poses that are compatible with two poses in the point of grasp configuration. This paper presents a novel approach for solving regrasp problem. The approach consists of a preprocessing and a planning stage. Preprocessing, which is done only once for a given robot, generates a look-up table which has information of kinematically feasible task space of end-effector through all the workspace. Then, using the table planning automatically determines possible intermediate location, pose and regrasp sequence leading from the pick-up to put-down grasp. Experiments show that the presented is complete in the total workspace. The regrasp planner was combined with existing path.

• Proceedings of the KSME Conference
• /
• 2001.06c
• /
• pp.548-553
• /
• 2001

Recently, much attention is imposed on the design of the fuel assemblies in the Pressurized Light Water Reactor (PWR). Spacer grid is one of the main structural components in a fuel assembly. It supports fuel rods, guides cooling water and protects the system from the external impact loads. Various space grids have been proposed and new designs are also being created. In this research, a new spacer grid is designed by the axiomatic approach. The Independence Axiom is utilized for the design. For conceptual design, functional requirements (FRs) are defined and corresponding design parameters (DPs) are found to satisfy FRs in sequence. Overall configuration and shapes are determined in this process. Detail design is carried out based on the result of the axiomatic design. For the detail design, the system performances are evaluated by using linear and nonlinear finite element analysis. The dimensions are determined by optimization. Some commercial codes are utilized for the analysis and design.

• Parasites, Hosts and Diseases
• /
• v.51 no.6
• /
• pp.739-742
• /
• 2013

A 52-year-old woman presented with lower back pain, progressive symmetrical paraparesis with sensory impairment, and sphincter disturbance. Magnetic resonance imaging (MRI) of the whole spine revealed multiple intradural extramedullary serpiginous-mass lesions in the subarachnoid space continuously from the prepontine to the anterior part of the medulla oblongata levels, C7, T2-T8, and T12 vertebral levels distally until the end of the theca sac and filling-in the right S1 neural foramen. Sparganosis was diagnosed by demonstration of the sparganum in histopathological sections of surgically resected tissues and also by the presence of serum IgG antibodies by ELISA. DNA was extracted from unstained tissue sections, and a partial fragment of mitochondrial cytochrome c oxidase subunit 1 (cox1) gene was amplified using a primer set specific for Spirometra spp. cox1. After sequencing of the PCR-amplicon and alignment of the nucleotide sequence data, the causative agent was identified as the larva of Spirometra erinaceieuropaei.

• Korean Journal of Microbiology
• /
• v.30 no.2
• /
• pp.108-112
• /
• 1992

To investigate the expression and the secretion of heterologous proteins in yeast, we constructed an yeast secretion vector and produced a human secretory protein, .alpha.-1-antitrypsin (.alpha.-1-AT), from yeast cells. The secretion vector pGAT8 was constructed by inserting the signal sequence of yeast acid phosphatase gene (PH05) into the .alpha.1-AT expression vector pGAT6 which contained .alpha.-1-AT cDNA fused to GAL10-CYC1 promotor. The .alpha.-1-AT was produced efficiently in the yeast cells transformed with plasmid pGAT8, which was onfirmed both by the .alpha.-1-AT activity assay and by the immunoblot method using .alpha.-1-AT antibody. We also showed the secretion of .alpha.-1-AT into the culture media and into the periplasmic space by immunoblot.

• 한국HCI학회:학술대회논문집
• /
• 2009.02a
• /
• pp.1265-1271
• /
• 2009

'I-Ching Storytelling Web-Cartoon Game' suggested by Prof. Shim and Research Group may provide users with the opportunity of writing story based on I-Ching. I-Ching is the cosmological thoughts intrinsic to East Asian culture. In the perspective of the narratology, I-Ching can bee seen as a kind of database of narratives since it classifies all events emerging from the meet between the actor(human-人) and the background(time/space-天地) as the story material into 384 narrative elements(sequence) and 64 themes(motive), and consistently constructs their causal relationships. So while trying to articulate I-ching with the digital storytelling methodology, we developed the web-cartoon game. With this game, users can creatively make their own story as a play by freely interpreting, retrieving, and recomposing those 386 narrative elements and 64 themes with the I-ching's narrative guideline.