• Title/Summary/Keyword: Sox2

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Emission Characteristics and Coefficients of Air Pollutants in Iron and Steel Manufacturing Facilities (제철제강시설의 대기오염물질 배출특성 및 배출계수 산정)

  • Kim, Byoung-Ug;Hong, Young-Kyun;Lee, Yeong-Seob;Yang, Seung-Pyo;Hyun, Geun-Woo;Yi, Geon-Ho
    • Journal of Environmental Health Sciences
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    • v.47 no.3
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    • pp.259-266
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    • 2021
  • Objectives: This study was conducted to identify the emissions characteristics of total particulate matter (TPM), fine dust (PM10, PM2.5), and gaseous pollutants (SOx, NOx) in iron and steel manufacturing facilities in order to investigate emissions factors suitable for domestic conditions. Methods: Total particulate matter (TPM), fine dust (PM10, PM2.5), and gas phase materials were investigated at the outlet of electric arc furnace facilities using a cyclone sampling machine and a gas analyzer. Results: The concentrations of TPM ranged from 1.64 to 3.14 mg/Sm3 and the average was 2.47 mg/Sm3. Particulate matter 10 (PM10) averaged 1.49 mg/Sm3 with a range of 0.92 to 1.99 mg/Sm3, and the resulting ratio of PM10 to TPM was around 60 percent. PM2.5/PM10 ranged from 33.7 to 47.9% and averaged 41.6%. Sulfur oxides (SOx) were not detected, and nitrogen oxides (NOx) averaged 6.8 ppm in the range of 5.50 to 8.67 ppm. TPM emission coefficients per product output were in the range of 0.60 to 1.26 g/kg, 0.13 to 0.79 g/kg for PM10 and 0.12 to 0.36 g/kg for PM2.5, and showed many differences from the emissions coefficients previously announced. An emissions coefficient for NOx is not currently included in the domestic notices, but the results were calculated to be 0.42 g/kg per product output. Conclusions: Investigation and research on emissions coefficients that can reflect the characteristics of various facilities in Korea should be conducted continuously, and the determination and application of unique emissions coefficients that are more suitable for domestic conditions are needed.

Comparison of Neural Cell Differentiation of Human Adipose Mesenchymal Stem Cells Derived from Young and Old Ages (연령별 지방 중간엽 유래 줄기세포의 신경세포로의 분화 능력 비교)

  • Jo, Jung-Youn;Kang, Sung-Keun;Choi, In-Su;Ra, Jeong-Chan
    • Development and Reproduction
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    • v.13 no.4
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    • pp.227-237
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    • 2009
  • Recently, adipose mesenchymal stem cells (AdMSC) that are similar to bone marrow MSC and blood derived MSC are thought to be another source for stem cell therapy. However, the diseases that can be applied for stem cells therapy are age-dependent degenerative diseases. Accordingly, the present study investigated the growth and differentiation potential to neural cells of human AdMSC (hAdMSC) obtained from aged thirty, forty and fifty. The growth of cells and cell viability were measured by passage and neural differentiation of hAdMSC was induced in neural differentiation condition for 10 days. Our results demonstrated that cell number, viability and morphology were not different from hAdMSC by age and passage. Immunofluorescence analysis of neural cell marker (TuJ1, NSE, Sox2, GFAP or MAP2) demonstrated no significant differences in neural cell differentiation by age and passage. As the number of passage was increased, the mRNA level of MAP2 and Sox2 was decreased in hAdMSC from age of 50 compared to hAdMSC from age of 30. In conclusion, the present study demonstrated that ability of neural cell differentiation of hAdMSC was maintained with ages, suggesting that autologous stem cells from aged people can be applied for stem cell therapy with age-dependent neural disease with the same stem cell quality and ability as stem cell derived from young age.

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Methodology development for measurement of gas phase ammonia and aerosol ammonium(${NH_4}^{+}$) in the atmosphere at real time (대기 중 암모니아 가스 및 암모늄 에어로졸의 실시간 측정 방법 개발)

  • 강은하;이재훈
    • Proceedings of the Korea Air Pollution Research Association Conference
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    • 2000.11a
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    • pp.96-98
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    • 2000
  • 암모니아는 대기 중에서 가장 대표적으로 존재하는 염기성 미량기체로서 SOx나 NOx와 같은 산성기체와 반응하여 대기중 산성도를 중화시키고 2차적 에어로졸을 생성한다. 암모니아가스는 이 반응에 의하여 에어로졸 내에서는 암모늄 이온(${NH_4}^{+}$)으로 존재하게 된다. 산성기체를 중화시킨다는 입장에서 염생성 반응은 산성기체의 제거 기작이 될 수 있으나 이 때 생성된 에어로졸은 주로 PM2.5 이하의 2차적 에어로졸로 존재하여 호흡기장애, 건물 부식, 시정 감소 등의 피해를 주는 오염물질이 된다. (중략)

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Destruction of HFC-134a Refrigerant in Gasification-melting Demonstration System (가스화용융(熔融) 실증 시스템에서 HFC-134a 냉매분해(冷媒分解) 특성(特性) 연구(硏究))

  • Jung, Dae Sung;Hong, Byeong Kwon;Kim, Woo Hyun;Roh, Seon Ah
    • Resources Recycling
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    • v.21 no.4
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    • pp.69-75
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    • 2012
  • Destruction of HFC-134a from ELV (End of Life Vehicle) were determined in a gasification-melting demonstration system of municipal solid waste (100ton/day). The injection system has been developed for the uniform injection of HFC-134a to the gasification-melting system. The destruction characteristics of HFC-134a and analysis of exhaust gases have been performed. The destruction efficiency was 99.995% for HFC-134a feeding of 3 kg/hr and the exhaust gases such as CO, SOx, NOx, HCl and HF satisfied the environmental standards.

Regulation of the sufABCDSE Operon by Fur

  • Lee, Joon-Hee;Yeo, Won-Sik;Roe, Jung-Hye
    • Journal of Microbiology
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    • v.41 no.2
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    • pp.109-114
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    • 2003
  • A promoter that is inducible by paraquat and menadione, the superoxide generators, independently of soxRS has been found in front of the sufABCDSE operon in Escherichia coli. Based on the observation that SufA is a holomog of IscA that functions in the assembly of iron sulfur cluster and the sufA promoter (sufAp) contains a putative Fur-binding consensus, we investigated whether this gene is regulated by Fur, a ferric uptake regulator, When examined in several sufAp-lacZ chromosomal fusion strains, sufAp was induced by EDTA, an iron chelator and a well-known Fur-inducer, The basal level of sufA expression increased dramatically in fur mutant, suggesting repression of sufAp by Fur. The derepression in fur mutant and EDTA-induction of sufA expression required nucleotides up to -61, where a putative Fur box is located. Purified Fur protein bound to the DNA fragment containing the putative Fur box between -35 and -10 promoter elements. The regulation by Fur and menadione induction of sufAp acted independently. The rpoS mutation increased sufA induction by menadione, suggesting that the stationary sigma factor RpoS acts negatively on sufA induction.

Beneficiation of Low Grade Anthracites (저품위 무연탄의 처리에 관한 연구)

  • 이재장;전호석;최우진
    • Resources Recycling
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    • v.5 no.2
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    • pp.45-51
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    • 1996
  • Domestic coal contains approximnlely 03 to 7 percentage of sulfur. When the suliur in coal is burned, exhaust gas , nay be thc causc of air pollution problcms as well as acid rain. Thc government dccideil lo strengthen the environmcnlal protection policy a1 the 270 ppm of SO, for the coal-Ered plants and to stari in Ian. 1, 1999. This study was carried out lo rcmove the stlfur and mineral mancrs in the samplw using wet msg~xiic separatol ant1 oil agglomeration apparatus. The rcsults for the wet magnetic separalion showed that the total sulfur removal from Kangnung coal sample was 60.8% with 82.6% combustible recovery. For the results of oil agglomeration testa, combustible recavety, ash nod sulfur rcmovcl horn Maro coal sample were 98.0, 70.9 and 95.7 percent, respectively.

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Healing Effect of Danggwisu-san (Dangguixu-san) on Femur Fractured Mice (당귀수산(當歸鬚散)이 대퇴골절 유발 생쥐에 미치는 영향)

  • Jeon, Dong-Hwi;Oh, Min-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.1
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    • pp.1-16
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    • 2021
  • Objectives This study was designed to evaluate the effects of Danggwisu-san (Dangguixu-san, DG) on bone repair from femur fracture in mice. Methods Mice were randomly divided into 4 groups (normal, control, positive control and DG 300 mg/kg-treated group). In order to investigate the effects of DG on gene expressions in experimental animals with fracture, we measured the levels of bone morphogenetic protein-2 (BMP2), cyclooxygenase-2 (COX2), Sox9, collagen type II alpha 1 chain (Col2a1), runt-related transcription factor 2 (Runx2), osterix genes. After the cytotoxicity test, we analyzed the levels of expression of osteocalcin and Runx2, and tumor necrosis factor-α (TNF-α), a pro-inflammatory cytokine. The process of fusion in the fracture was also investigated by gross examination. Results Through in vivo BMP2, COX2 gene expression significantly decreased. Sox9 significantly increased. Col2a1, Runx2, osterix gene expression also increased as well, but there was no statistical significance. The degree of unilateral fracture fusion investigated by gross examination was significantly faster than those of the other groups. Through in vitro the level of TNF-α in macrophages was increased by DG in a dose-dependent mannerand and 250 and 500 ㎍/mL showed statistical significance. Osteocalcin and Runx2 genes expressions increased when DG was treated in osteoblasts. Conclusions DG promotes the healing of the fracture through the expression of bone repair-related genes and TNF-α production. This study may set the foundation for the clinical application of DG to the patients with bone fractures.

Air Pollution Protection onboard by Seawater and Electrolyte

  • An Suk-Heon
    • Journal of Advanced Marine Engineering and Technology
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    • v.30 no.1
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    • pp.93-101
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    • 2006
  • This research makes a new attempt to apply the activated seawater by electrolysis in the development of two-stage wet scrubber system to control the exhaust gas of large marine diesel engines. First, with using only seawater that is naturally alkaline (pH typically around 8.1). the $SO_2\;and\;SO_3$ are absorbed by relatively high solubility compared to other components of exhaust pollutants, and PM (Particulate Matter) is removed through direct contact with sprayed seawater droplets. Besides, the electrolyzed alkaline seawater by electrolysis, which contains mainly NaOH together with alkali metal ions $(i.e.\;Na^+,\;Mg^{2+},\;Ca^{2+})$, is used as the absorption medium of NOx and $CO_2$. Especially, to increase NOx absorption rate into the alkaline seawater. nitric oxide (NO) is adequately oxidized to nitrogen dioxide $(NO_2)$ in the acidic seawater, which means both volume fractions are adjusted to identical proportion. The results found that the strong acidic seawater was a valid oxidizer from NO to $NO_2$ and the strong alkaline seawater was effective in $CO_2$ absorption In the scrubber test, the SOx reduction of nearly $100\%$ could be achieved and also led to a sufficientPM reduction. Hence, the author believes that applying seawater and its electrolyte would bring the marine air pollution control system to an economical measure. Additionally it is well known that NOx and SOx concentration has a considerable influence on the $N_2O$ emission of green house gas. Although the $N_2O$ concentration exhausted from diesel engines is not as high, the green house gas effect is around 300 times greater than an equivalent volume of $CO_2$. Therefore, we investigated the $N_2O$ removal efficiency with using the electrolyzed seawater too. Finally this research would also plan to treat the effluent by applying electro-dialysis and electro-flotation technique s in the future.

Healing Effect of Yukmijihwang-tang on Fracture Factor and Morphological Changes in Femur Fractured Mice (육미지황탕(六味地黃湯)이 대퇴골절 동물모델의 골절 유합인자 및 형태학적 변화에 미치는 영향)

  • Kim, Hyun-Seok;Jeon, Dong Hwi;Oh, Min-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.30 no.4
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    • pp.17-30
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    • 2020
  • Objectives The purpose of this study is to evaluate the healing effect of Yukmijihwang-tang (YM) on femur fractured mice. Methods Mice were randomly divided into 6 groups: normal, control, positive control, YM with low, medium, high dosage each. All groups were prepared with femur fracture and treated diffrently. In order to measure bone regeneration effects, we analysed the levels of cyclooxygenase-2 (COX2), bone morphogenetic protein-2 (BMP2), collagen type II alpha 1 chain (Col2a1), Sox9, runt-related transcription factor 2 (Runx2), and osterix genes expressed in bone. For morphological analysis, muscles were removed and femur was observed with naked eye. Results COX2 gene expression in bone marrow significantly decreased. BMP2 gene expression significantly increased. Col2a1 gene expression significantly increased. Sox9 gene expression increased as well. Runx2 gene expression in bone marrow increased, but there was no statistical significance. Osterix gene expression significantly increased. Union of the fracture site progressed more in YM group compared to the control group. The fracture union score was significantly decreased in YM group compared to the control group. Conclusions YM showed anti-inflammatory effect, promoted bone regeneration by stimulating the bone regeneration factor. In conclusion, YM can help fracture healing and it well be applied clinically to patients with fracture.

The PM2.5 Emission Source Contribution Analysis using The PMF Model in Urban Area (PMF 모델을 이용한 도심지역 PM2.5 오염원 기여도 분석)

  • Koo, Tai-Wan;Hong, Min-Sun;Moon, Su-Ho;Kim, Ho-Jung
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.3
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    • pp.905-914
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    • 2019
  • In this study, The PMF model was used to identify pollutant sources and their contribution to pollution sources of $PM_{2.5}$. The contribution of A city to each source was 19.8% for Secondary Sulfate, followed by Mobile 19.5%, Industry 16.0%, Biomass Buring 14.1%, Secondary Nitrate 14.1%, Oil Combustion 11.6%, Aged Sea Salt 2.6%, Soil 2.5% and so on. Sulfate and Ammonium concentrations were the highest contributing sources in the source profile, which was analyzed to be Secondary Aerosols produced by Photochemical Reactions of gaseous precursors (SOx and ammonia gas) in the atmosphere.