• The Korean Journal of Physiology and Pharmacology
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• 제16권2호
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• pp.139-144
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• 2012

It has been reported that activation of metabotropic glutamate receptor 1 (mGluR1) can mediate endocannabinoid-induced short-term depression of synaptic transmission in cerebellar parallel fiber (PF)-Purkinje cell (PC) synapse. mGluR1 has signaling pathways involved in intracellular calcium increase which may contribute to endocannabinoid release. Two major mGluR1-evoked calcium signaling pathways are known: (1) slow-kinetic inward current carried by transient receptor potential canonical (TRPC) channel which is permeable to $Ca^{2+}$; (2) $IP_3$-induced calcium release from intracellular calcium store. However, it is unclear how much each calcium source contributes to endocannabinoid signaling. Here, we investigated whether calcium influx through mGluR1-evoked TRPC channel contributes to endocannabinoid signaling in cerebellar Purkinje cells. At first, we applied SKF96365 to inhibit TRPC, which blocked endocannabinoid-induced short-term depression completely. However, an alternative TRP channel inhibitor, BTP2 did not affect endocannabinoid-induced short-term depression although it blocked mGluR1-evoked TRPC currents. Endocannabinoid signaling occurred normally even though the TRPC current was mostly blocked by BTP2. Our data imply that TRPC current does not play an important role in endocannabinoid signaling. We also suggest precaution in applying SKF96365 to inhibit TRP channels and propose BTP2 as an alternative TRPC inhibitor.

• Journal of Home Health Care Nursing
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• 제27권3호
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• pp.241-249
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• 2020

Purpose: This study aimed to investigate possible ways to expand the services of home-visit nursing through a review of the progress, achievements, and obstacles of home-visit nursing; a pilot project of an integrated home-service; the application of the Omaha System; as well as a case analysis of providing home-visit nursing services. Method: An integrated review was conducted using various source materials, including laws, previous studies, and a case analysis. Results: In case analysis of providing visiting nursing service, rehabilitation nursing, end-of-life nursing, and dementia care showed high nursing needs. It was necessary that the various home visit nursing services in the intervention area of the Omaha System, administrative services, case management, and center operation activities were all included in the payment systems of long-term care insurance. Conclusion: In the future, home visit nursing services of long-term care insurance should be reborn in the form of a center for integrated case management in the community, which would set long-term goals until the time of a client's death and encompass the realm of human rights for health, quality of daily life, and a dignity of life.

• Nuclear Engineering and Technology
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• 제55권12호
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• pp.4335-4349
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• 2023

Nuclear marine propulsion has been emerging as a next generation carbon-free power source, for which proper passive residual heat removal systems (PRHRSs) are needed for long-term safety. In particular, the characteristics of unlimited operation time and compact design are crucial in maritime applications due to the difficulties of safety aids and limited space. Accordingly, a compact and long-term-operable PRHRS has been proposed with the key design concept of using both air cooling and seawater cooling in tandem. To confirm its feasibility, this study conducted system design and a transient analysis in an accident scenario. Design results indicate that seawater cooling can considerably reduce the overall system size, and thus the compact and long-term-operable PRHRS can be realized. Regarding the transient analysis, the Multi-dimensional Analysis of Reactor Safety (MARS-KS) code was used to analyze the system behavior under a station blackout condition. Results show that the proposed design can satisfy the design requirements with a sufficient margin: the coolant temperature reached the safe shutdown condition within 36 h, and the maximum cooling rate did not exceed 40 ℃/h. Lastly, it was assessed that both air cooling and seawater cooling are necessary for achieving long-term operation and compact design.

• Journal of Environmental Science International
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• 제12권7호
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• pp.809-816
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• 2003

The short-term version of Industrial Source Complex Model(ISCST3) was evaluated for estimating short-term concentrations using criteria pollutant(SO$_2$, NO$_2$, CO, PM10) data from emission inventory of Young Tong area in Suwon for the year 2002. The contribution of pollutant concentration from point, line, area sources was found 21.8, 76.5 and 1.6%. Statistical parameters, such as correlation coefficient, index of agreement(IA), normalized mean square error(NMSE) and fractional bias(FB) were calculated for each pollutants. The model performance were found good for PM10(82%) and NO$_2$(69%), but poor for SO$_2$(34%) and CO(13%).

• The Transactions of the Korean Institute of Electrical Engineers D
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• 제50권12호
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• pp.590-596
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• 2001

The pre-emphasis is an essential process for speech signal processing. Widely used two methods are the typical method using a fixed value near unity and te optimal method using the autocorrelation ratio of the signal. This study proposes a new pre-emphasis method using the short-term energy difference of speech signal, which can effectively compensate the glottal source characteristics and lip radiation characteristics. Using the proposed pre-emphasis, speech analysis, such as spectrum estimation, formant detection, is performed and the results are compared with those of the conventional two pre-emphasis methods. The speech analysis with 5 single vowels showed that the proposed method enhanced the spectral shapes and gave nearly constant formant frequencies and could escape the overlapping of adjacent two formants. comparison with FFT spectra had verified the above results and showed the accuracy of the proposed method. The computational complexity of the proposed method reduced to about 50% of the optimal method.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 한국지하수토양환경학회 2003년도 추계학술발표회
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• pp.565-569
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• 2003

One-year-long groundwater-level data have been collected from 18 wells in Cheon-an area. The result of barometric efficiency, autocorrelation, cross-correlation and statistical distribution evaluated from the measurement data shows that groundwater-level measurements from observation wells are the principal source of information about aquifer characteristics. Data from WA-2 has high barometric efficiency as well as steady decreasing auto-correlation coefficient, which means nonleaky confined aquifer, Most aquifers in this study show the unconfined properties so that barometric efficiencies are mostly low and the coefficients of cross-correlation between groundwater-level and precipitation are commonly high. This study showed that the long-term groundwater-level monitoring data without artificial stress such as pumping would give accurate information about aquifer characteristics.

• Journal of Radiation Protection and Research
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• 제28권2호
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• pp.137-143
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• 2003

Annual radiation dose limit to radiation worker was substantially lowered in Korea by the adoption of 1990 recommendations of the International Commission on Radiation Protection (ICRP 60) in its legislation. On the other hand, radiation management environment in nuclear power plants is getting more worse because of the accumulation of radiation sources inside the system and the frequent need for maintenance according as the operation years of nuclear power plants increase. Therefore, Korea Hydro & Nuclear power Co., Ltd. (KHNP) has established a long-term 10 years plan from 2001 to 2010 for the reduction of radiation dose to workers. The plan is aimed for the reduction of annual dose per unit averaged over 5 years from 0.9 man-Sv in 2001 to 0.75 man-Sv in 2010 by radiation source reduction, equipment/tool improvement or new equipment development for easy maintenance, and the improvement of administration and system.

• ETRI Journal
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• 제43권2호
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• pp.288-298
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• 2021

Abstractive text summarization is a process of making a summary of a given text by paraphrasing the facts of the text while keeping the meaning intact. The manmade summary generation process is laborious and time-consuming. We present here a summary generation model that is based on multilayered attentional peephole convolutional long short-term memory (MAPCoL; LSTM) in order to extract abstractive summaries of large text in an automated manner. We added the concept of attention in a peephole convolutional LSTM to improve the overall quality of a summary by giving weights to important parts of the source text during training. We evaluated the performance with regard to semantic coherence of our MAPCoL model over a popular dataset named CNN/Daily Mail, and found that MAPCoL outperformed other traditional LSTM-based models. We found improvements in the performance of MAPCoL in different internal settings when compared to state-of-the-art models of abstractive text summarization.

• Honam Mathematical Journal
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• 제26권4호
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• pp.589-608
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• 2004

We investigate the multiplicity of the periodic solutions of the nonlinear wave equation with jumping nonlinearity. By category theory we prove that the jumping problem has at least 2k+1 solutions for the positive source term.

• Proceedings of the Korean Nuclear Society Conference
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• 한국원자력학회 1998년도 추계학술발표회요약집
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• pp.334-334
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• 1998