• Asian Pacific Journal of Cancer Prevention
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• 제15권15호
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• pp.6181-6186
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• 2014

This meta-analysis was conducted to examine whether the genotype status of Val158Met polymorphism in catechol-O-methyltransferase (COMT) is associated with endometrial and ovarian cancer risk. Eligible studies were identified by searching several databases for relevant reports published before January 1, 2014. Pooled odds ratios (ORs) were appropriately derived from fixed-effects or random-effects models. In total, 15 studies (1,293 cases and 2,647 controls for ovarian cancer and 2,174 cases and 2,699 controls for endometrial cancer) were included in the present meta-analysis. When all studies were pooled into the meta-analysis, there was no evidence for significant association between COMT Val158Met polymorphism and ovarian cancer risk (Val/Met versus Val/Val: OR=0.91, 95% CI=0.76-1.08; Met/Met versus Val/Val: OR=0.90, 95% CI=0.73-1.10; dominant model: OR=0.90, 95% CI=0.77-1.06; recessive model: OR=0.95, 95% CI=0.80-1.13). Similarly, no associations were found in all comparisons for endometrial cancer (Val/Met versus Val/Val: OR 0.97, 95% CI=0.77-1.21; Met/Met versus Val/Val: OR=1.02, 95% CI=0.73-1.42; dominant model: OR=0.98, 95% CI=0.77-1.25; recessive model: OR=1.02, 95% CI=0.87-1.20). In the subgroup analyses by source of control and ethnicity, no significant associations were found in any subgroup of population. This meta-analysis strongly suggests that COMT Val158Met polymorphism is not associated with increased endometrial and ovarian cancer risk.

• 한국가스학회지
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• 제25권1호
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• pp.30-39
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• 2021

세계적으로 천연가스는 환경적, 정치적, 지역적인 이유로 중요한 에너지원으로 부상하고 있다. 우리나라에서 천연가스는 액화천연가스로 수입하고 있으며, 석탄과 원전을 대체하는 연료나 원료의 활용에서 액화천연가스는 증가하고 있다. 우리나라는 천연가스를 수입에 의존하고 있기 때문에 공급에 대한 안정성분석이 중요하다. 따라서, 본 연구에서는 우리나라 수입구조의 위험도 분석을 통하여 공급리스크를 줄이고 안정적인 공급과 수요를 위한 방안을 제시하였다. 공급위험도를 감소시키기 위해 한 국가로부터의 수입 집중도를 낮춰야 하며, 가스공급안정성 지수 (gas supply security index, GSSI)가 낮은 국가의 수입비중을 낮추고 상대적으로 안정적인 국가인 러시아로부터 수입을 증가시켜야 한다. 또한, 수입국가의 수를 늘리거나 안정적 공급이 가능한 국가와의 관계 유지는 우리나라 수입가스의 공급안정성지표 (total gas supply security index, TGSSI)에 긍정적인 영향을 줄 것으로 분석되었다.

• Fisheries and Aquatic Sciences
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• 제21권7호
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• pp.19.1-19.11
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• 2018

Background: Traditionally, East-Asians (Korea, Japan, and China) utilize seaweeds as a food source and ingredient in traditional medicine. Korea is one of the biggest seaweed producer and consumer in the global trade. Especially, side dishes made from seaweeds are very popular in the traditional Korean cuisines. Seaweeds are popular as fresh vegetable salads and soup or eaten as snacks. Main body: Seaweeds are rich in essential nutrients, minerals, and vitamins as well as a promising source of novel bioactive compounds. The compounds (polysaccharides, polyphenols, and sterols) present in the edible Korean seaweeds possess important bioactive properties such as antioxidant, anti-inflammation, anticancer, anti-diabetic, and anticoagulant properties. Thus, the long-term consumption of seaweed has a potential to reduce the risk of cancer, diabetes, obesity, and inflammation-related complications. However, seaweed consumption is limited to the small population around the globe. Thus, it is important to increase the awareness of the health benefits of seaweeds consumption among the general population. Short conclusion: In the present study, we discussed some popular green and red edible Korean seaweeds and their health-promoting properties. This study might be useful to increase the public awareness of the consumption of seaweed as a food source.

• 한국산업보건학회지
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• 제11권1호
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• pp.78-84
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• 2001

A CFD simulation of airflow and temperature field in a heated room has been described in this paper. The thermal wall jet created by a radiator greatly influences the airflow pattern, temperature distribution. The area close La a heat source has a higher risk of air-borne contamination and imposes a harmful effect on occupants in that area. The predicted flow field, temperature results show good agreement with the measured data. As the results were compared with experimental data, the applicability of CFD was satisfactorily verified. Also, the CFD simulation can capture the natural convective flow features. If a CFD simulation is applied ventilation design with a heat source, An effective design will be attained. Further study is required to improve the accuracy of CFD simulation.

• 한국안전학회지
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• 제26권4호
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• pp.127-134
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• 2011

A traffic accident which happens in Expressway during dense fog is more likely to cause the sequential accidents and high death rate. So, the preventive measures shall be taken at dangerous areas to enhance the efficiency of roads and minimize the accidents and the resultant damages. So, it is necessary to find out the characteristics of freeway zone which has high risk of fog occurrence and to establish the comprehensive safety strategy on installation and operation of the safety equipment. In this study, I developed a fog forecasting model by using the freeway fog data. This model can be used as the fog forecasting model in dealing with fog problems when new road is planned. The model was developed by using a statistical analysis technique or the regression analysis, focusing on the variables such as geographical features and regional conditions, distances to water sources and the area of water source. I have segmented the models by classifying the area into inland area and coastal area. The distance to water source and area of the water source located around the freeway were found to be main factors causing fog.

• 보건행정학회지
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• 제32권1호
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• pp.29-44
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• 2022

Background: This study was conducted to analyze the impact of having a usual source of care on health behaviors of the middle aged and the elderly, in order to investigate the potential effect of enhancing primary health care in a Korean context. Methods: This study constructed a balanced panel of middle-aged and elderly samples using the Korea Health Panel 2016-2018, and fixed-effect models were used to analyze the data. Results: Among three sets of dependent variables (physical activity, smoking, drinking), statistically significant results were found only in physical activity. Subgroup analysis showed that this effect was not observed in the late elderly (aged 75 and older) and those without chronic diseases. Conclusion: Results of the study implied that enhancing primary health care among middle age and the elderly may have an effect on improving health behaviors. Moving forward to person-centered primary health care from disease-focused primary health care should be considered in high-risk groups such as the middle aged and the elderly with chronic diseases.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2009년도 추계학술발표대회
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• pp.241-242
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• 2009

As software is becoming increasing important to the human society, so does the effort to produce them is also increasing.. All of these efforts can be at risk when source code of the application is reverse engineered by the software pirate. Many attempts have been made to protect Intellectual Property Rights (IPR); one of the newest attempts to protect IPR is software watermarking. It is used to prove ownership right when IPR are violated, and also prevents the bandit from altering the code for his own use. In this paper we are presenting a new technique for software watermarking know as Dictionary Based Software Watermarking (DBSW). DBSW works by embedding dummy instructions in source code with the help of predefined mapping already available in the dictionary. These instructions are identical to the normal instructions of the program and are hard to identify or to extract from the watermarked program. With the help of DBSW we not only can stop source code alteration but can also identify the buyer how has distributed the pirated copy.

• 대한한방내과학회지
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• 제31권4호
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• pp.870-879
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• 2010

Objective : This study is about stroke risk factors which may differ between countries. Methods : We recruited 1725 ischemic stroke patients from multiple-centers. We analyzed stroke risk factors: hypertension, diabetes mellitus, dyslipidemia, depression, cardiac source, smoking, waist-to hip ratio, alcohol intake, physical activity, and psychosocial stress. We then compared risk factor results from other countries (the INTERSTROKE study) with this study. Results : 10 risk factors are related to stroke incidence. They were somewhat different between this study and the INTERSTROKE study. Conclusions : Hypertension is the most important risk factor of stroke, and other 9 risk factors also should be managed to prevent stroke incidence. Frequency of risk factors were different from the INTERSTROKE study. I think it could be partly due to differences of ethnicity and age. More studies are needed to describe characteristics of risk factors of Koreans.

• Nutrition Research and Practice
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• 제6권1호
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• pp.68-77
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• 2012

Flavan-3-ols are a subclass of flavonoids found in a variety of foods including teas. The effects of flavan-3-ols on the risk of metabolic syndrome (MetS) have been investigated, generally focusing on tea catechins or individual flavan-3-ol rich foods, but there is little information on dietary flavan-3-ols intake and risk of MetS in population-based studies. In this cross-sectional study, we examined the association between dietary flavan-3-ols intake and the risk of MetS in Korean adults. Subjects comprised 1,827 men and 2,918 women aged 20-69 years whose data was included in the 2008 Korean National Health and Nutrition Examination Survey. This survey was conducted between January 2008 and December 2008. Total flavan-3-ols intakes were calculated from 24-hour dietary recalls using a flavonoids database. Thirty percent of the male subjects and 24% of the female subjects were reported as having MetS. In the female subjects, flavan3-ols intake was inversely associated with the risk of MetS after adjusting for potential confounders (5th vs. 1st quintile, OR=0.64, 95% CI=0.45-0.91, P for trend=0.384). The main food source of flavan-3-ols was green tea followed by apples and grapes. Among MetS components, flavan-3-ols intake was inversely associated with the risk of high blood pressure after adjusting for potential confounders (5th vs. 1st quintile, OR=0.64, 95% CI=0.45-0.90, P for trend=0.005). No significant association between flavan-3-ols intake and risk of MetS was found in the male subjects. After stratified analysis by obesity (BMI ${\geq}$ 25 or BMI < 25), however, flavan3-ols intake was inversely related to the risk of hypertension in non-obese men. These results suggest that dietary flavan-3-ols intake may have beneficial effects on MetS risk by reducing the risk of hypertension. The effects of flavan-3-ols intake dependent on obesity need further investigation.

• 한국안전학회지
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• 제27권5호
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• pp.219-223
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• 2012

For an off-site consequence analysis at nuclear power plant, MELCOR Accident Consequence Code System(MACCS) II code is widely used as a software tool. In this study, the algorithm of web-based off-site consequence analysis program(OSCAP) using the MACCS II code was developed for an Integrated Leak Rate Test (ILRT) interval extension and Level 3 probabilistic safety assessment(PSA), and verification and validation(V&V) of the program was performed. The main input data for the MACCS II code are meteorological, population distribution and source term information. However, it requires lots of time and efforts to generate the main input data for an off-site consequence analysis using the MACCS II code. For example, the meteorological data are collected from each nuclear power site in real time, but the formats of the raw data collected are different from each site. To reduce the efforts and time for risk assessments, the web-based OSCAP has an automatic processing module which converts the format of the raw data collected from each site to the input data format of the MACCS II code. The program also provides an automatic function of converting the latest population data from Statistics Korea, the National Statistical Office, to the population distribution input data format of the MACCS II code. For the source term data, the program includes the release fraction of each source term category resulting from modular accident analysis program(MAAP) code analysis and the core inventory data from ORIGEN. These analysis results of each plant in Korea are stored in a database module of the web-based OSCAP, so the user can select the defaulted source term data of each plant without handling source term input data.