• Archives of Plastic Surgery
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• 제37권4호
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• pp.452-456
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• 2010

Purpose: The schwannoma is a benign peripheral nerve tumor arising from the Schwann cell of the nerve sheath. Only 2-8% of schwannomas arise in the hand and wrist. Misdiagnosis is frequent such as ganglion and neurofibroma. This article documents and clarifies the clinical features of schwannomas arising in the hand and wrist, and emphasizes importance of differential diagnosis and meticulous surgical extirpation under magnification. Methods: The author reviewed clinical features of 15 patients with pathologic final diagnosis of schwannoma developed in hand and wrist during the last 12 years from 1998 through 2009. The review included the sex, age of onset, duration, preoperative diagnosis, location, involved nerve, preoperative symptoms and. Postoperative sequelae after surgical extirpation of the lesion with magnification, or without magnification of the surgical fields. Results: The chief complaints were slow growing firm mass in all patients, and followed by pain in 40%, and paresthesia in 40% respectively. The lesions were developed solitarily in 14 patients (93%). The postoperative pathologic diagnosis and preoperative diagnosis were coincided with only in 6 patients (40%). Other preoperative diagnosis were soft tissue tumor in 4 patient (26.6%), and ganglion in 3 patients (20%), and neurofibroma in 2 patients (13%). In all patients who were undergone surgical excision under the fields of magnification, all symptoms were subsided without any sequelae. Meanwhile muscle weakness, paresthesia, hypoesthesia and /or accidental nerve resection developed after surgical excision with naked eye. Conclusion: Schwannoma in hand most commonly appears as a slow growing solitary mass with pain or paresthesia. The chance of preoperative misdiagnosis was 60% in this series. To provide good prognosis and less sequelae, careful and elaborate diagnostic efforts and meticulous surgical excision under the magnification are necessary in management of schwannoma.

• 대한후두음성언어의학회지
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• 제20권2호
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• pp.148-150
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• 2009

Schwannoma are benign, solitary and encapsulated tumors originating from the Schwann cells of the nerve sheath. About 25% to 40% of all schwannomas are found in the head and neck and the acoustic nerve is most frequently involved, but schwannomas of the tongue is rare. When they do occur, treatment is simple. However, diagnosis is invariably delayed because of the vagueness of symptoms. Recently, authors experienced a case of schwannoma occurred in the base of tongue and the tumor was successfully removed through intraoral approach. So we report this case with literature review.

• Tuberculosis and Respiratory Diseases
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• 제63권1호
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• pp.78-82
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• 2007

대개 양성 고립성 신경초종의 경우 무증상으로 우연히 발견되며, 흉수로 인한 호흡곤란을 동반하는 증례는 매우 드물다. 저자들은 호흡곤란과 흉통을 주소로 내원하여 흉수를 동반한 양성 고립성 신경초종으로 진단된 2예를 경험하였기에 보고하는 바이다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제35권6호
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• pp.494-498
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• 2009

Schwannomas are tumors which originate from the neuroectodermal Schwann cell of cranial, intraspinal, peripheral and autonomic nerve sheaths, and they are solitary, benign, slow growing and well encapsulated neoplasm. Schwannomas are usually asymptomatic. No strong gender or age predominance exists. The incidence of extracranial schwannomas in the head and the neck region varies from 25~45%. In addition, schwannomas are rare in the maxillary sinus or buccal space. In this paper, it diagnosed and treated a 54-years old female patient, who had schwannoma in the maxillary sinus derived from infraorbital nerves, the branch of the left trigeminal nerve, and a 19-years old male patient, who had schwannoma arose in the buccal space derived from the buccal branch of the right facial nerve. There was no particular complication except sensory extinction of the nerve in the female patient and paralysis by the nerve in the male patient. It is determined those two cases of schwannoma in the rare portion is valuable and herein, it reports those with literature discussions.

• 대한두개안면성형외과학회지
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• 제14권1호
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• pp.61-64
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• 2013

Schwannomas are well-differentiated solitary benign tumors that originate from the schwann cells of the nerve sheath. They can readily occur in the head and neck regions, but the schwannoma originating from the infraorbital nerve is extremely rare and usually painless, slow-growing, and without specific symptoms. The author experienced a rare case of infraorbital schwannoma, which was completely removed through the intraoral approach. A 20-year-old woman was admitted to our hospital for a painless, solid and circular mass located on the right infraorbital region. The eyeball movement and visual field were normal. There was no globe displacement or proptosis. Preoperative computed tomography demonstrated $13{\times}10{\times}5mm$-sized soft tissue mass. On March 2011, the mass was removed through an intraoral approach. On histopathological examination, the gross specimen consisted of a smooth, well-encapsulated and light yellowish solid mass, measuring $12{\times}7{\times}5mm$. Microscopically, it presented a typical manifestation of schwannoma with Antoni A area with Verocay body, and Antoni B area on H&E stain. The result of the immunohistochemical staining was positive for the S-100 protein. The patient had hypoesthesia of the nasal septum and vestibule in the postoperative period, and this finding confirmed that the internal nasal branch of infraorbital nerve was the nerve in which the schwannoma originated. Infraorbital schwannomas are very rare and must be included in the differential diagnosis of the orbital masses inferior to the eyeball. In the case of early diagnosis, the small-sized infraorbital schwannomas can be completely removed without any scar through an intraoral approach.

• Tuberculosis and Respiratory Diseases
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• 제44권3호
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• pp.649-654
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• 1997

저자들은 우상복부동통을 내원한 흉부 x선상 정상이었던 43세 여자 환자에서 흡입침생검술로 확진하여 개흉술로 완전절제한 우하흉부에 발생한 신경최종 1예를 경험하고 함께 보고한다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제11권2호
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• pp.81-86
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• 1989

말초 신경 조직에서 발생되는 종양은 신경섬유종, 신경초종, 파립세포종, 악성신경초종 등이 있다. 신경섬유종은 2가지 형태로 분류될 수 있다. 첫째 형태는 단독형 신경섬유종이고, 둘째는 신경섬유종 혹은 Von Recklinghausen's병으로 불리우는데 이는 주로 피부, 신경조직, 뼈, 연조직에 기형을 유발할 수 있고, 선천적이며, 가족력을 나타낸다. 단독형 신경섬유종은 양성이며, 경계는 명확하나 capsule에 의해 싸여 있지 않으며, 피부나 피하조직에 sessile 혹은 pedunculated 형태로 나타난다. 두경부의 어느 부위에나 나타날 수 있으며, 구강내의 호발 부위는 혀, 협점막, 구개 순이다. 단독형 신경섬유종은 방사선에 의한 치료에 효과가 적으며, 재발율이 낮고, 치료는 주로 외과적 절제술로 제거를 하고, 결손부를 삼각흉피판(D-P flap)과 설피판(tongue flap)으로 수복하여 현재까지 합병증 없이 양호한 결과를 얻었다.

• Journal of Chest Surgery
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• 제37권12호
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• pp.1036-1039
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• 2004

기관 및 기관지 종양은 대부분이 악성 종양이며 양성 종양은 10% 이내에 불과하다. 특히 폐에 발생하는 원발성 신경성 종양은 전체 폐종양의 2% 이하로 대부분이 Schwann세포에서 기원한다고 알려져 있다. 이러한 종양은 주로 고립성 양성 종양으로 나타나며 드문 경우에 악성의 형태를 보이기도 한다. 기관지내 신경초종은 폐의 원발성 종양 중에서 발생빈도가 매우 낮은 것으로 알려져 있다. 저자들은 기관지내 신경초종으로 폐엽절제술을 시행한 2예를 보고하는 바이다.

• 대한치과의사협회지
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• 제22권1호통권176호
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• pp.75-79
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• 1984

Neurilemoma (Schwannoma) is a solitary encapsulated benigh tumor and apparently derived from Schwann cells of the nerve sheath. This is a case of 17-year-old Korean female with the neurilemoma of the tongue. Chief complaint of the patient was painless palpable mass on left tongue body. Diagnosis was established by histologic examination after simple surgical excision of tumor mass. A brief review of related literatures was made.

• 대한기관식도과학회지
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• 제6권1호
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• pp.113-117
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• 2000

A neurilemmoma of the facial nerve presenting as a parotid mass is a rare neoplasm and has been reported infrequently in the surgical literature. Diagnosis is usually by tissue biopsy intraoperatively and treatment is surgical with preservetion of facial function. This is a case of a solitary neurilemmoma involving the main trunk of the facial nerve in the posterior part of parotid gland continuing up to vertical segment of the facial nerve, in which the facial nerve had to be sacrificed and free autogenous nerve grafting was done.