• 대한두개안면성형외과학회지
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• 제18권3호
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• pp.218-221
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• 2017

A solitary fibrous tumor is a relatively uncommon neoplasm that usually occurs in the pleura but occurs extremely rarely in the oral cavity. Reported herein is a rare case of a solitary fibrous tumor in the buccal cheek mucosa. A 50-year-old man visited the authors' hospital due to a buccal cheek mass whose size had increased. Excisional biopsy was done under local anesthesia. After the excisional biopsy, the patient was diagnosed to have a solitary fibrous tumor. In immunohistochemistry, the patient's solitary fibrous tumor was characterized by the expression of CD34 and CD99 on the neoplastic cells, and negativity for Bcl-2 and S-100. No recurrence or complication occurred for a period of 5 years. The growth of a primary solitary fibrous tumor in the buccal cheek mucosa is extremely rare and has been rarely reported in the South Korean medical literature. A solitary fibrous tumor must be distinguished from other spindle cell tumors. Presented herein is a case of primary solitary fibrous tumor in the buccal cheek mucosa. The relevant literature is briefly reviewed.

• Journal of Korean Neurosurgical Society
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• 제56권3호
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• pp.265-268
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• 2014

Solitary fibrous tumor is rare benign mesenchymal neoplasm. The spinal solitary fibrous tumor is extremely rare. The authors experienced a case of intramedullary solitary fibrous tumor of cervicothoracic spinal cord in a 48-year-old man with right lower extremity sensory disturbance. Spinal MRI showed intradural mass lesion in the level of C7-T1, the margin between the spinal cord and tumor was not clear on MRI. A Left unilateral laminectomy and mass removal was performed. Intra operative finding, the tumor boundary was unclear from spinal cord and it had intramedullary and extramedullary portion. After surgery, patient had good recovery and had uneventful prognosis. Follow up spinal MRI showed no recurrence of tumor.

• Journal of Chest Surgery
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• 제27권1호
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• pp.76-80
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• 1994

A solitary fibrous tumor in the pleura has been reported occasionally, but extremely rare in themediastinum. The histogenesis of this tumor has been still in controverse, but recent studies paid attention to it a mesenchymal origin by the immunohistochemical and ultrastructural bases. A few cases, reported in the literature, suggest that the mediastinal solitary fibrous tumor occurs more commonly in adult and shows slightly higher incidence in women. Its aggressive behavior such as recurrence rate and distant metastasis, is more prominant than reported in solitary fibrous tumor of the pleura. No single histologic feature allows an assumption definite prognosis. Surgical resection of this tumor is usually curative although the recurrence or distant metastasis are reported in about half of the patients. This report is a case of solitary fibrous tumor in the mediastinum in a 16-year-old female patient.She underwent surgical resection and her postoperative result was satisfactory.

• 대한두경부종양학회지
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• 제15권2호
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• pp.243-245
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• 1999

Solitary fibrous tumors are commonly arise in the pleura and less commonly in extrapleural sites. In head and neck area, solitary fibrous tumors can occur in nose, paranasal sinus, soft palate, epiglottis, thyroid, parotid and submandibular gland. To our knowledge, this is the 5th case of solitary fibrous tumor arising from the parotid gland in English literature. We report a case of solitary fibrous tumor occurred in the superficial lobe of right parotid gland which was successfully treated by superficial parotidectomy with preservation of the facial nerve.

• Journal of Korean Neurosurgical Society
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• 제39권1호
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• pp.64-67
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• 2006

Solitary fibrous tumor is a spindle cell neoplasm that can arise in any place of the body. Intracranial solitary fibrous tumors are rare. To our knowledge, only 57 cases with intracranial lesion have been reported. In Korea three cases have been reported. Our case was a 23-year-old woman who presented with morning headache. MRI showed a large intra-axial mass involving falx with typically isointense and heterogeneous strong enhancement on T1 weighted image in the right parieto-occipital region. Histologically the tumor showed spindle shaped cells within matrix with thick collagen deposition, hypercellularity, focal necrosis, and pleomorphism. Immunohistochemical study demonstrated diffuse positivity for CD34, Vimentin, Reticulin. In case of the intracranial tumors involving the meninges, we also should consider the solitary fibrous tumor with immunohistochemical staining for accurate diagnosis.

• Journal of Korean Neurosurgical Society
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• 제37권3호
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• pp.232-234
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• 2005

We report a rare case of a patient with meningeal solitary fibrous tumor. A 60-year-old woman presented with right leg monoparesis. Brain magnetic resonance imaging demonstrates a well enhancing huge mass, located in left parietal lobe. Cerebral angiography demonstrating increased vascularity in area of the tumor, which had feeder vessels extending from the internal carotid artery and external carotid artery. A presumptive diagnosis of meningioma or hemangiopericytoma was considered. At surgery, the consistency was firm and had destroyed the dura and skull. A gross total resection was performed. Immunohistochemically, tumor was strongly, and widely, positive for CD34 and vimentin. There was no staining for epithelial membrane antigen(EMA), S-100 protein, cytokeratin, and glial fibrillary acidic protein (GFAP). Differential diagnosis of intracranial solitary fibrous tumor includes fibroblastic meningioma, meningeal hemangiopericytoma, neurofibroma, and schwannoma.

• 대한세포병리학회지
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• 제12권2호
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• pp.111-115
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• 2001

Solitary fibrous tumor on the pleura is rare but should be included in the differential diagnosis on a peripheral pulmonary nodule. Cytologic features of solitary fibrous tumor of the pleura is not familar to the pathologist and may be misdiagnosed as malignancy. We report fine needle aspiration cytologic(FNAC) findings of a case of solitary fibrous tumor misdiagnosed as adenocarcinoma in a 48-year-old woman. The FNAC displayed a mixture of bland-looking spindle cells and clusters of epithelioid cells, which have hyperchromatic nuclei with prominent nucleoli. The helpful finding to distinguish It from other circumscribed benign and malignant lesions is the presence of fibromyxoid matrix admixed with blood vessels and thin collagen fibers. Familiarity with these features is essential to avoid misdiagnosis and overtreatment.

• Journal of Chest Surgery
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• 제46권4호
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• pp.295-298
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• 2013

Solitary fibrous tumor is a rare spindle cell mesenchymal tumor entity, with either benign or malignant behavior that cannot be accurately predicted by histological findings. An intrapulmonary site of origin is even rarer. We report a case of a 51-year-old woman in whom an abnormal nodule in the lower right lung was detected during staging for sigmoid adenocarcinoma. The nodule was excised and pathological examination revealed an intrapulmonary solitary fibrous tumor.

• 대한기관식도과학회지
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• 제8권1호
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• pp.87-91
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• 2002

Solitary fibous tumor of pleura is a rare and slow vowing neoplasm. The histogenesis of this tumor is thought as mesenchymal origin by immunohistochemical and ultrastructural bases. This case report is of a 69-year-old female who presented severe dyspnea and orthopnea with long-term history. Preoperative chest X-ray an chest CT revealed huge and hemithorax-occupying heterogenous mass and cardiomegaly. She underwent surgical resection and a 22 X 18 X 10 cm sized visceral pleural based mass was evacuated. Histologic findings of tumor showed patternless proliferation in a fibrocollagenous and well vasculized stroma. Immnohistochemical staining revealed strong positive in CD34, that are compatible with solitary fibrous tumor of pleura. The patient was discharged without any complications and no evidence of recurrence was found after 2 years.

• Journal of Chest Surgery
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• 제38권2호
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• pp.168-171
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• 2005

고립성 섬유성 종양은 주로 흉막에서 발생하는 드문 종양으로 중피하 중간엽에서 기원하며 드물게 흉막 외에서 발생하기도 한다. 많은 경우에서 증상이 없이 우연히 발견되나 다른 중요 장기를 침범하거나 종양의 크기가 커질 경우 증상이 나타나기도 한다. 일반적으로 진단은 영상의학적 검사와 세침흡인을 통한 생검으로 하며 면역조직화학검사를 시행하여 더 정확히 판별할 수 있다 대부분의 경우 양성의 경과를 보이며 병변의 완전한 제거 여부가 가장 중요한 예후 인자가 된다고 알려져 있다. 저자들은 우하엽에 발생한 폐실질 내에 생긴 고립성 섬유성 종양을 채기 절제술로 치험하여 이에 보고하는 바이다