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Protective effect of Oxya chinensis sinuosa methanol extract on UVB-induced damage in human retinal pigment epithelial cells

  • Hyun Jung Lim;Sohyun Park;Joon Ha Lee;In-Woo Kim;HaeYong Kweon;Minchul Seo
    • International Journal of Industrial Entomology and Biomaterials
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    • v.47 no.2
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    • pp.90-98
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    • 2023
  • The human eye, constantly exposed to solar radiation, can be damaged by UV radiation. In particular, ultraviolet B (UVB)-induced damage plays an important role in retinal degeneration and cell aging. In this study, we investigated the protective effects of the methanol extract of Oxya chinensis sinuosa (OCM), an edible insect known for its high protein content (64.2%), and various pharmacological effects, on human retinal pigment epithelial cells. ARPE-19 cells were treated with OCM and subsequently UVB irradiated. Our results showed that OCM effectively attenuates UVB-induced cell damage by reducing MAPK phosphorylation (JNK and p38 MAPK). Additionally, OCM increased the phosphorylation of Akt, and cell cycle regulators, including p21 and p27, in a dose-dependent manner. Moreover, OCM treatment increased ARPE-19 cell proliferation by activating the S6K1/S6 pathway. This study suggests that OCM prevents UVB-induced retinal cell damage by increasing cell proliferation via ROS reduction, suggesting its potential as a functional therapeutic superfood against retinal cell damage.

Astronomical Records in the Goguri Annal of the Three Kingdoms Period

  • Ki-Won Lee;Byeong-Hee Mihn
    • Journal of Astronomy and Space Sciences
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    • v.41 no.2
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    • pp.107-119
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    • 2024
  • It is known that Chang-Hwa Park (1889-1962) transcribed a chronicle of the Goguryeo kingdom (BC 37-AD 668) of Korea (hereafter Goguri annal) from literature of the time that is no longer available. However, the authenticity of his transcription remains disputed. This study attempts to verify whether the Goguri annal is a pseudograph by analyzing the astronomical records in the annal. Although the Goguryeo kingdom fell in the year 668, the Goguri annal contains records up to the year 536. In this study, we have classified the astronomical records into eight categories and clustered them into two groups: a calendrical data group of reign-name and calendar date categories, and a celestial phenomena group of solar eclipse, trespass, comet, daylight appearance of Venus, meteor/meteorite, and other categories. The records of each category have been compared with those of the Samguksagi (History of the Three Kingdoms), Chinese chronicles, and with the results of modern computations wherever possible. From this comparison, we have not found any critical record that would indicate that the Goguri annal is a pseudograph, although the same astronomical records, with the exception of a few, are also found in the Samguksagi and Chinese chronicles.

1-Kestose Blocks UVB-Induced Skin Inflammation and Promotes Type I Procollagen Synthesis via Regulating MAPK/AP-1, NF-κB and TGF-β/Smad Pathway

  • Jihye Baek;Jong-Hwa Kim;Jiwon Park;Do Hyun Kim;Soonok Sa;Jung-Sook Han;Wonyong Kim
    • Journal of Microbiology and Biotechnology
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    • v.34 no.4
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    • pp.911-919
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    • 2024
  • Solar UVB irradiation cause skin photoaging by inducing the high expression of matrix metalloproteinase (MMPs) to inhibit the expression of Type1 procollagen synthesis. 1-Kestose, a natural trisaccharide, has been indicated to show a cytoprotective role in UVB radiation-induced-HaCaT cells. However, few studies have confirmed the anti-aging effects. In the present study, we evaluated the anti-photoaging and pathological mechanism of 1-kestose using Human keratinocytes (HaCaT) cells. The results found that 1-kestose pretreatment remarkably reduced UVB-generated reactive oxygen species (ROS) accumulation in HaCaT cells. 1-Kestose suppressed UVB radiation-induced MMPs expressions by blocking MAPK/AP-1 and NF-κB p65 translocation. 1-Kestose pretreatment increased Type 1 procollagen gene expression levels by activating TGF-β/Smad signaling pathway. Taken together, our results demonstrate that 1-kestose may serve as a potent natural trisaccharide for inflammation and photoaging prevention.

Evaluation of Minimum Detectable Activity for Underwater Radiation Monitoring System (수중 방사선 모니터링 시스템의 성능평가를 위한 수중 내 최소검출가능농도 산출)

  • Jangguen Park;Sung-Hee Jung;Daemin Oh;Jinho Moon
    • Journal of Radiation Industry
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    • v.17 no.3
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    • pp.219-224
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    • 2023
  • A high-efficiency underwater radiation monitoring system, HydroGamma, has been developed for detecting 137Cs and 131I in the event of waterborne radiation contamination. The system consists of a 3-inch NaI (Tl) detector, solar panels for power supply, data acquisition and transmission modules, and batteries. HydroGamma also includes a 40K calibration source for remote performance evaluation and energy calibration. In this study, some simulations and experiments were carried out to evaluate the minimum detectable activities (MDA) of HydroGamma. We installed the HydroGamma at Tapjeongho Lake in Nonsan-si and acquired background data since MDA is calculated based on the experimental background data. The results show that the minimum detectable activities for 137Cs and 131I were 1.78Bq L-1 and 1.81Bq L-1, respectively even though the gamma rays emitted from 40K(1,460 keV) affect the minimum detectable activities for them.

Seasonal Changes in Micrometeological Factors of a Costal Sand Dune Grassland Ecosystem in Hakampo, Taeanhaean National Park, Korea (태안해안국립공원 학암포 해안사구 초지생태계의 미기상인자 계절변화)

  • Lee, Na-Yeon;Choi, In Young
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.15 no.1
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    • pp.9-16
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    • 2013
  • Coastal sand dune area is an important ecosystem as an ecotone which is located between coastal area and terrestrial area. In order to understand the sand dune ecosystem in terms of its habitat characteristics, micrometeorological analysis was carried out in a coastal sand dune in Hakampo, Taeanhaean National Park, Korea. Micrometeorological measurements were made to monitor air and soil temperatures, relative humidity, soil water content, rainfall, solar radiation, wind speed, and wind direction. In contrary to a forest ecosystem, the coastal sand dune grassland ecosystem was relatively hotter and very humid with heavy rainfalls concentrated between June and July. The seasonal change of daily mean soil temperature was greater than that of air temperature by $2{\sim}3^{\circ}C$. Daily mean soil water content was less than 10% throughout the year. Also, the maximum wind speed of 156.7 m $s^{-1}$ was recorded on 7 October 2011. The observed seasonal wind direction was different from those observed at Seosan by KMA (Korea Meteorological Administration). To better understand the habitat characteristics in a costal sand dune grassland ecosystem, long-term multi-year measurements are needed.

Effects of Different Kinds of Salt on the Quality of Wet Noodles (소금종류별에 따른 첨가가 생면의 품질에 미치는 효과)

  • Lee, Jeong-Mi;Kim, So-Young;Park, Kun-Young
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.12
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    • pp.1776-1780
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    • 2011
  • The effects of different kinds of salt on the qualities of weight, volume, water absorption rate, turbidity, pH, textural characteristics, and sensory evaluation of wet noodles were studied. The salts employed in this study were purified salt (PS), solar salt (SS), solar salt without bittern (SSWB), roasted salt (RS) and bamboo salt (BS, $1{\times}$). The weight, volume, and water absorption rate of the noodles decreased with the 2% addition of different kinds of salts compared to the noodles without any added salt. The turbidity of the noodles decreased when BS (0.484), RS (0.489), or SSWB (0.489) were added to the noodles much more than when PS (0.508) was added. The pH of both wet noodles and cooked noodles was higher when BS, RS, or SS were added than when the others were added. The springiness and cohesiveness of the noodles were both increased with the addition of the salts. BS, RS and SS especially increased the springiness and cohesiveness of the noodles. In sensory evaluations of appearance, taste, texture and overall acceptance, BS received the highest scores. From the results, adding salt to wet noodle preparations is important to increase the quality of the noodles. BS showed the best overall results among the salts employed in this study.

Analysis of Air Current Measurements at External Induction-Style Kitchen and Bathroom Vents (외기유인형 주방·욕실 배기구의 기류측정 분석)

  • Lee, Yong-Ho;Kim, Seong-Yong;Park, Jin-Chul;Hwang, Jung-Ha
    • Journal of the Korean Solar Energy Society
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    • v.32 no.6
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    • pp.76-84
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    • 2012
  • This study conducted experiments to measure air currents in an experimental building according to external conditions, types of induction ducts, and types of internal sockets by applying an external induction duct comprised of inducing openings and lines and induction units to the kitchen and bathroom vents at the rooftop of a super high-rise apartment building in order to help to improve the venting performance. The study also proposed the optimization of the external induction-style kitchen and bathroom vents capable of wind power generation. (1) As for air current distribution according to vent velocity changes, it increased the venting performance of the kitchen and bathroom by 1.0m/s at vent velocity of 2.0m/s or higher and allowed for wind power generation. (2)As for air current distribution according to external velocity changes, it increased the venting performance of the kitchen and bathroom by 1.2m/s at external velocity of 2.0m/s or higher and allowed for wind power generation. (3)As for air current distribution according to wind direction changes($0{\sim}180^{\circ}$), it was favorable for higher vent velocity when the angle between the external induction duct direction and prevailing wind direction was within ${\pm}30^{\circ}$. (4)As for air current distribution according to induction duct type, the[M1] type combining the inducing openings and lines with the induction units recorded the highest improvement effects in the kitchen and bathroom venting performance by increasing vent velocity by 46%. (5)As for air current distribution according to the changing types of internal sockets where the main ducts of the kitchen and bathroom are connected to the external induction ducts, the venturi tube type[Sv] increased vent velocity by 66% based on the smoothest external inflow.

The Arch Type PV System Performance Evaluation of Multi Controlled Inverter for Improve the Efficiency (효율개선을 위한 다중제어 인버터방식의 아치형 PV System 성능 분석)

  • Lee, Mi-Yong;Park, Jeong-Min
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.11
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    • pp.5452-5457
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    • 2012
  • It is saving material cost and construction cost by replacing conventional building materials, and It has advantages for aesthetic value. In the Europe, the United States, Japan and other country research about BIPV is actively being carried out and marketability is also being infinity expanding. Arch type PV systems efficiency characteristics is different depending on PV array's directly connection, parallel connection and arches angle, but is a lack of analysis on this nowadays. When the arch type PV system design up, they consider about aesthetic value and they didn't consider about generation efficiency. In this paper, we try to improve the efficiency through optimization of arch type PV system and estimation of the efficiency parameters of the arch type PV system, such as latitude, longitude, temperature, insolation, arch angle and each kind loss from system organization. For improving Arched PV system efficiency, proposed multiple control inverter system, and using simulation tool of Arched PV system "Solar pro", flat-plate type and many arch type PV system configuration the driving characteristics were compared and analyzed.

Improvement of light scattering properties of Ag/ZnO back-reflectors for flexible silicon thin film solar cells (플렉서블 실리콘 박막 태양전지용 Ag/ZnO 후면반사막의 광산란 특성 향상)

  • Baek, Sanghun;Lee, Jeong Chul;Park, Sang Hyun;Song, Jinsoo;Yoon, Kyung Hoon;Wang, Jin-Suk;Cho, Jun-Sik
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.06a
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    • pp.97.1-97.1
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    • 2010
  • 유연금속기판위에 DC 마그네트론 스퍼터링을 이용하여 Ag/ZnO 이중구조의 후면반사막을 증착하고 Ag 표면조도 변화에 따른 후면반사막의 반사특성 변화와 플렉서블 비정질 실리콘 박막 태양전지의 셀 특성에 미치는 영향을 조사하였다. Substrate구조를 갖는 플렉서블 실리콘 박막 태양전지에서는 실리콘 박막 광흡수층의 상대적으로 낮은 광 흡수율로 인하여 입사광에 대한 태양전지 내에서의 광 산란 및 포획이 태양전지 효율을 증대시키는데 매우 중요한 역할을 하는 것으로 알려져 있다. 플렉서블 실리콘 박막 태양전지에서의 후면반사막은 광 흡수층에서 흡수되지 않는 입사광을 다시 반사시켜 광 흡수를 증대시키며 이때 후면반사막 표면에서 반사 빛을 효율적으로 산란시켜 이동경로를 증대시킴으로써 광 흡수율을 더욱 향상시킬 수 있다. 본 연구에서는 유연금속 기판위에 Ag와 ZnO:Al($Al_2O_3$ 2.5wt%) 타겟을 사용한 DC 마그네트론 스퍼터링법으로 Ag/AZO 이중구조의 후면반사막을 제조하고, Ag 박막의 표면형상 변화와 이에 따른 후면반사막의 반사도 변화를 비교, 분석하였다. 증착 조건 변화에 따른 표면 형상 및 반사 특성은 Atomic Force Mircroscope(AFM), Scanning electron miroscopy(SEM), UV-visible-nIR spectrometry를 통하여 분석하였다. 서로 다른 표면 거칠기를 갖는 후면반사막 위에 n-i-p구조의 a-Si:H 실리콘 박막 태양전지를 제조한 후 태양전지 동작 특성에 미치는 영향을 조사하였다. n,p층은 13.56MHz PECVD, i층은 60MHz VHF CVD를 사용하여 각각 제조 하였으며, Photo I-V, External Quantum Efficiency(EQE) 분석을 통하여 태양전지 특성을 조사 하였다. SEM 분석결과 공정 온도가 증가 할수록 Ag 박막의 표면 결정립 크기도 증가하였으며, AFM분석을 통한 Root-mean-square(Rms)값은 상온에서 $500^{\circ}C$로 증착온도가 증가함에 따라 6.62nm에서 46.64nm까지 증가하였다. Ag 박막의 표면 거칠기 증가에 따라 후면반 사막의 확산 반사도도 함께 증가하였다. 공정온도 $500^{\circ}C$에서 증착된 후면반사막을 사용하여 a-Si:H 태양전지를 제조하였을 때 상온에서 제조한 후면반사막에 비하여 단락전류밀도 (Jsc)값은 9.94mA/$cm^2$에서 13.36mA/$cm^2$로 증가하였으며, 7.6%의 가장 높은 태양전지 효율을 나타내었다.

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Electrical properties of CuInSe2 thin films formed by selenization of RF sputtered Cu-In-Se2 precursors for solar cell applications (Cu-In-Se2 전구체의 Selenization에 의해 형성된 CuInSe2 박막의 태양전지 응용을 위한 전기적 특성평가)

  • Jeong, Chaehwan;Park, Chanyoung;Kim, Jinhyeok;Lee, Suk Ho
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.06a
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    • pp.79-79
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    • 2010
  • 다른 물질에 비해 많은 우수한 특성을 가지고 있는 CuInSe2(CIS)박막 태양전지는 많은 연구자들에 의해 개발되어 오고 있다. CIS의 대표적인 장점으로는 직접천이형 밴드갭, 높은 흡수계수, 열 안정화상태 및 p형으로의 전도성물질의 가능성 등 다양하다. 또한 간단한 구조를 이용하여 유리같은 싼 기판을 이용하기 때문에 저가형 태양전지로서 많은 각광을 받고 있다. CIGS태양전지는 CIS의 In 사이트에 Ga을 도핑함으로서 만들어지는데 밴드갭은 약 1.4eV이다. CIS박막을 만드는 많은 방법이 존재하나 구성원소로부터 최적화된 조성을 찾을수 있는 방법이 가장 중요한 요소 중의 하나로 인식되고 있으며, 이런점에서 증발법 및 스퍼터링법 등 같은 진공방식이 비진공방식에 비해 훨씬 간편하게 조성비를 맞출수 있다. 그 중에 스퍼터링법은 대면적 박막태양전지로의 가능성으로 비출어 볼때 산업화를 위한 좋은 후보군이 될 수 있다. Selenization을 하기전에 Cu-In-Se의 전구체 조합은 여러개의 타겟으로부터 동시 스퍼터링법이나 다층 전구체법을 사용하여 준비되는데 어떤 방법이 되던지 Se의 부가적인 공급은 불가피하다. 지금까지 많은 관련 연구의 대부분인 구조적, 조성비적 그리고 광학적인 특성평가에 집중되어 오고 있는데, 전기적특성평가의 경우는 면저항, 비저항 같은 간단한 결과 위주로 보고되어 오고 있다. 또한 캐리어농도와 이동도에 대한 보고가 있음에도 불구하고 이해되기에는 충분치 못한 면이 많다.본 발표에서는 태양전지 제조 전단계로서 소다라임유리기판(SLG)위에 Mo의 유무에 따라 CIS박막의 전기적인 특성 변화에 대한 내용을 담고 있다. 소다라임유리($2cm{\times}2cm$)를 기판으로 사용하여 아세톤-에탄올 용액에 초음파세척을 수행하고, Mo 후면전극을 DC 스퍼터링방식을 이용하여 증착을 한다. SLG와 Mo이 코팅된 SLG를 각각 RF 스퍼터 챔버에 이송한 후 수증기 제거를 위해 약 10분간 예열을 한다. 샘플에 대한 전기적특성은 Hall효과 측정장치에 의해 측정이 되며 전기전도도, 캐리어농도, 이동도 및 전도형에 대한 정보가 각각의 변수에 따라 조사된돠. 부가적으로 구조적, 조성비적인 특성을 SEM,XRD 및 EDX를 통해 조사를 하여 전기적 특성에 따른 관계성을 검토한다. SLG와 Mo가 코팅된 SLG위의 CIS박막은 전기적으로 약간 다른 특성을 보일 것으로 예측되며, 이러한 기대를 바탕으로 조성비가 이상적인 화학양론에 근접할 때 p형으로서 제시될 수 있다는 것을 보여줄 것이다.

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