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The Effects of Digital Therapy for Stroke Patients in Korea: Meta-analysis (국내 뇌졸중 환자를 위한 디지털 치료의 효과: 메타분석)

  • Jae-Hun Jung
    • Journal of The Korean Society of Integrative Medicine
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    • v.11 no.4
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    • pp.1-15
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    • 2023
  • Purpose : This study investigates the effectiveness of digital therapy for stroke patients in Korea. Methods : A comprehensive database search was performed using KCI, Science on, e-article, RISS, KISS and Korea OpenMed databases for randomized controlled trials (RCTs) that studied the effects of digital therapy on patients who had a stroke. This study includes RCTs published from January 2000 to July 15, 2022, which fulfilled the inclusion and exclusion criteria. A total 697 studies were screened and 30 studies were included in the final analysis. Methodological quality was assessed with the Cochrane's RoB (risk of bias) tool. Meta-analysis was performed using CMA 4.0 software. Results : A total of 56 effect sizes were calculated from the 30 selected studies. As a result of the analysis, the overall effect size of digital therapy was .59 (95 % CI=.43-.74). When classified according to type of intervention, VR (virtual reality) (g=.58, 95 % CI=.40-.75), and CACR (computer assisted cognitive rehabilitation) (g=.62, 95 % CI=.30-.95) were statistically significant. VR showed medium to large effect sizes in cognitive function (g=.78, 95 % CI=.20-1.37), psychosocial function (g=.63, 95 % CI=.20-1.07), and physical function (g=.61, 95 % CI=.38-.83). In the CACR, there was a large effect size in cognitive function (g=.84, 95 % CI=.52-1.15), but there was no significant difference in psychosocial function. Also, there was no significant difference between the two interventions in activities of daily living and no significant difference in the effect size of both interventions according to the intervention session. Furthermore, medium to large effect sizes were found for subacute and chronic stroke patients according to the duration of disease. Conclusion : This study presents evidence that digital therapy has a positive effect on various functions of stroke patients in Korea. The researchers expect to actively accept the new paradigm of digital therapy and continue to apply digital therapy in clinical practice.

Effect of digital therapies on balance and gait in children with cerebral palsy: A systematic review (디지털 치료제가 뇌성마비 아동의 균형 및 보행에 미치는 효과: 체계적 고찰)

  • Jung-Hyun Kim
    • Journal of Korean Physical Therapy Science
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    • v.30 no.4
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    • pp.92-110
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    • 2023
  • Background: Digital therapeutics are software medical devices that provide evidence-based treatments to prevent, manage, and treat disease. Digital therapies have recently been shown to be effective in motivating children with cerebral palsy as a tool in neuropsychological therapy. Digital therapies improve postural control, balance and gait in children with cerebral palsy. Therefore, this study aims to investigate the effects of digital therapies on balance and gait in children with cerebral palsy and to provide guidelines for prescribing digital therapies for children with cerebral palsy. Design: A Systematic Review Methods: This study searched for English-language articles published in medical journals from January 2000 to July 2023 using PubMed and MEDLINE based on the year of initiation of the digital therapy. The search terms used in the study were 'digital technology' OR 'digital therapeutic' OR 'mobile application' OR 'mobile health' OR 'virtual reality' OR 'game' AND 'cerebral palsy', 'balance' 'gait' as the main keywords. The final article was assigned an evidence level and a Physiotherapy Evidence Database (PEDro) score to assess the quality of clinical trials studies. Results: The digital therapies applied to improve balance and gait in children with cerebral palsy are game-based virtual reality training and the Nintendo Wii Fit program. Both digital therapy interventions had a significant effect on improving balance in children with cerebral palsy, and virtual reality training significantly improved balance and gait. However, there were no significant improvements in balance and gait within two weeks of treatment, regardless of the type of digital intervention. Conclusion: The study suggests that this data will be important in building the evidence base for the effectiveness of digital therapies on balance and gait in children with cerebral palsy and in advancing clinical protocols.

A study on program development for character web drama production (캐릭터 웹드라마 제작을 위한 프로그램 개발 연구)

  • Hyun-soo Lee;Min-Ha Kim;Ji-Won Seo;Sung-Jin Jo;Jong-Won Lee;Jung-Yi Kim
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.5
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    • pp.591-596
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    • 2023
  • This study developed a program that can produce videos easily and conveniently, focusing on teenage media producers. Through user research, we identified the needs and problems of teenage producers, and implemented a character customization function desired by users and an emotion and action recommendation system using GPT. In the rendering process, the final image was created by combining audio and video using OpenCV and FFmpeg. Teenage users who do not have expertise in video production can customize web drama characters through a simple interface and receive recommendations for emotions and actions with the help of GPT. The program of this study is expected to be a tool that can help teenage users who do not have expertise in editing and directing to produce high-quality videos, lower the entry barrier to video production, and contribute to the development of the one-person media industry. do. In the future, we plan to provide a video production environment considering mobile or vertical resolution versions.

Experimental Studies on the Skin Barrier Improvement and Anti-inflammatory Activity based on a Bibliometric Network Map

  • Eunsoo Sohn;Sung Hyeok Kim;Chang Woo Ha;Sohee Jang;Jung Hun Choi;Hyo Yeon Son;Cheol-Joo Chae;Hyun Jung Koo;Eun-Hwa Sohn
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2023.04a
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    • pp.40-40
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    • 2023
  • Atopic dermatitis is a chronic inflammatory skin diseases caused by skin barrier dysfunction. Allium victoralis var. Platyphyllum (AVP) is a perennial plant used as vegetable and herbal medicine. The purpose of this study was to suggest that AVP is a new cosmetic material by examining the effects of AVP on the skin barrier and inflammatory response. A bibliometric network analysis was performed through keyword co-occurrence analysis by extracting author keyword from 69 articles retrieved from SCOPUS. We noted the anti-inflammatory activity shown by the results of clustering and mapping from network visualization analysis using VOSviewer software tool. HPLC-UV analysis showed that AVP contains 0.12 ± 0.02 mg/g of chlorogenic acid and 0.10 ± 0.01 mg/g of gallic acid. AVP at 100 ㎍/mL was shown to increase the mRNA levels of filaggrin and involucrin related to skin barrier function by 1.50-fold and 1.43-fold, respectively. In the scratch assay, AVP at concentrations of 100 ㎍/mL and 200 ㎍/mL significantly increased the cell migration rate and narrowed the scratch area. In addition, AVP suppressed the increase of inflammation-related factors COX-2 and NO and decreased the release of β-hexosaminidase. This study suggests that AVP can be developed as a functional cosmetic material for atopy management through skin barrier protection effects, anti-inflammatory and anti-itch effects.

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Applicability of Daoyin Exercise with Therapeutic Exercise for Shoulder Pain: A Systematic Review and Meta-analysis (치료적 운동을 포함한 도인운동의 어깨 통증에 대한 적용 가능성 탐색: 체계적 문헌고찰 및 메타 분석)

  • Hyeonsun Park;Sanghyeon Park;Jiho Lee;Seohyun Park;Dongho Keum
    • Journal of Korean Medicine Rehabilitation
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    • v.33 no.4
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    • pp.79-93
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    • 2023
  • Objectives The purpose of this study is to investigate therapeutic exercise and to provide the evidence of daoyin exercise for shoulder pain. Methods Electronic databases including PubMed, EMBASE, China National Knowledge Infrastructure, Science ON, Oriental Medicine Advanced Searching Integrated System were searched up to October 2022. We selected randomized controlled trials. The quality of studies was assessed by Cochrane risk of bias tool. Meta-analysis were perfomed by Review Manager software. Results Eighteen randomized controlled trials were collected in accordance with the selection and exclusion criteria. Among the 18 trials, 7 trials used strengthening exercise, 4 trials used stablilization exercise, 5 trials used both types of intervention, and 2 trials used daoyin exercise. The study characteristics, results and method of intervention were analyzed. Meta-analysis showed that therapeutic exercise appeared to more effective than no treatment group for shoulder pain (standardized mean difference=-1.18, 95% confidence interval=-1.44 to 0.91, Z=8.82, p<0.00001; chi2=2.71, p=0.61; I2=0%). Conclusions All of 18 selected studies reported the effectiveness of therapeutic exercise for shoulder pain. Combining strengthening and stablilization exercise is considered the most efficient way for shoulder pain. Based on this study, well-designed studies should be performed to be evidence of the use of daoyin exercise for shoulder pain.

Prediction of Draft Force of Moldboard Plow according to Travel Speed in Cohesive Soil using Discrete Element Method (이산요소법을 활용한 점성토 환경에서의 작업 속도에 따른 몰드보드 플라우 견인력 예측)

  • Bo Min Bae;Dae Wi Jung;Dong Hyung Ryu;Jang Hyeon An;Se O Choi;Yeon Soo Kim;Yong Joo Kim
    • Journal of Drive and Control
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    • v.20 no.4
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    • pp.71-79
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    • 2023
  • In the field of agricultural machinery, various on-field tests are conducted to measure design load for optimal design of agricultural equipment. However, field test procedures are costly and time-consuming, and there are many constraints on field soil conditions due to weather, so research on utilizing simulation to overcome these shortcomings is needed. Therefore, this study aimed to model agricultural soils using discrete element method (DEM) software. To simulate draft force, predictions are made according to travel speed and compared to field test results to validate the prediction accuracy. The measured soil properties are used for DEM modeling. In this study, the soil property measurement procedure was designed to measure the physical and mechanical properties. DEM soil model calibration was performed using a virtual vane shear test instead of the repose angle test. The DEM simulation results showed that the prediction accuracy of the draft force was within 4.8% (2.16~6.71%) when compared to the draft force measured by the field test. In addition, it was confirmed that the result was up to 72.51% more accurate than those obtained through theoretical methods for predicting draft force. This study provides useful information for the DEM soil modeling process that considers the working speed from the perspective of agricultural machinery research and it is expected to be utilized in agricultural machinery design research.

Efficacy of Acupuncture for Parkinson's Disease over the Last Decade: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Yeonju Kim;Yigun Lim;Subin Ahn;Junyeop Oh;Yoonbyeong Chae;Yoomin Choi;Jong Uk Kim
    • Journal of Acupuncture Research
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    • v.41 no.1
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    • pp.29-52
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    • 2024
  • The aim of this review is to consolidate findings from clinical investigations spanning the past decade regarding the impact of acupuncture on Parkinson's disease (PD). The objective is to assess the efficacy of acupuncture as a therapeutic approach to PD, with the intention of informing future clinical practices and advancing the foundation for subsequent research endeavors in this area. A comprehensive literature search was conducted to identify clinical trials exploring the effects of acupuncture on PD between January 2014 and August 2023. Databases search included PubMed, EMBASE, CNKI, OASIS, KISS, KMBASE, RISS, and ScienceON. Quantitative evidence from randomized controlled trials (RCTs) was systematically reviewed, and the methodological quality of the included studies was assessed using Cochrane's risk of bias tool. Meta-analysis was performed using Review Manager (RevMan) 5.4.1 software. The systematic review encompassed a total of 38 RCTs involving 2,786 participants. Meta-analysis of 12 studies revealed that individuals treated with a combination of acupuncture and Western medicine exhibited notable improvements compared to those receiving Western medicine alone or sham acupuncture alongside Western medicine. However, the overall quality of the RCTs was deemed low, and no serious adverse events were reported. Across clinical investigations conducted in the past decade, acupuncture appears to hold promise as a complementary treatment for PD patients when administered alongside Western medicine. Nevertheless, this study identifies certain limitations that warrant consideration in future research endeavors. Enhanced emphasis on conducting high-quality RCTs is imperative to comprehensively evaluate the efficacy of acupuncture in managing PD.

Volume Control using Gesture Recognition System

  • Shreyansh Gupta;Samyak Barnwal
    • International Journal of Computer Science & Network Security
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    • v.24 no.6
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    • pp.161-170
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    • 2024
  • With the technological advances, the humans have made so much progress in the ease of living and now incorporating the use of sight, motion, sound, speech etc. for various application and software controls. In this paper, we have explored the project in which gestures plays a very significant role in the project. The topic of gesture control which has been researched a lot and is just getting evolved every day. We see the usage of computer vision in this project. The main objective that we achieved in this project is controlling the computer settings with hand gestures using computer vision. In this project we are creating a module which acts a volume controlling program in which we use hand gestures to control the computer system volume. We have included the use of OpenCV. This module is used in the implementation of hand gestures in computer controls. The module in execution uses the web camera of the computer to record the images or videos and then processes them to find the needed information and then based on the input, performs the action on the volume settings if that computer. The program has the functionality of increasing and decreasing the volume of the computer. The setup needed for the program execution is a web camera to record the input images and videos which will be given by the user. The program will perform gesture recognition with the help of OpenCV and python and its libraries and them it will recognize or identify the specified human gestures and use them to perform or carry out the changes in the device setting. The objective is to adjust the volume of a computer device without the need for physical interaction using a mouse or keyboard. OpenCV, a widely utilized tool for image processing and computer vision applications in this domain, enjoys extensive popularity. The OpenCV community consists of over 47,000 individuals, and as of a survey conducted in 2020, the estimated number of downloads exceeds 18 million.

Vibrational energy flow in steel box girders: Dominant modes and components, and effective vibration reduction measures

  • Derui Kong;Xun Zhang;Cong Li;Keer Cui
    • Steel and Composite Structures
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    • v.50 no.3
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    • pp.347-362
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    • 2024
  • Controlling vibrations and noise in steel box girders is important for reducing noise pollution and avoiding discomfort to residents of dwellings along bridges. The fundamental approach to solving this problem involves first identifying the main path of transmission of the vibration energy and then cutting it off by using targeted measures. However, this requires an investigation of the characteristics of flow of vibration energy in the steel box girder, whereas most studies in the area have focused on analyzing its single-point frequency response and overall vibrations. To solve this problem, this study examines the transmission of vibrations through the segments of a steel box girder when it is subjected to harmonic loads through structural intensity analysis based on standard finite element software and a post-processing code created by the authors. We identified several frequencies that dominated the vibrations of the steel box girder as well as the factors that influenced their emergence. We also assessed the contributions of a variety of vibrational waves to power flow, and the results showed that bending waves were dominant in the top plate and in-plane waves in the vertical plate of the girder. Finally, we analyzed the effects of commonly used stiffened structures and steel-concrete composite structures on the flow of vibration energy in the girder, and verified their positive impacts on energy regionalization. In addition to providing an efficient tool for the relevant analyses, the work here informs research on optimizing steel box girders to reduce vibrations and noise in them.

Monitoring Posterior Cerebral Perfusion Changes With Dynamic Susceptibility Contrast-Enhanced Perfusion MRI After Anterior Revascularization Surgery in Pediatric Moyamoya Disease

  • Yun Seok Seo;Seunghyun Lee;Young Hun Choi;Yeon Jin Cho;Seul Bi Lee;Jung-Eun Cheon
    • Korean Journal of Radiology
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    • v.24 no.8
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    • pp.784-794
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    • 2023
  • Objective: To determine whether dynamic susceptibility contrast-enhanced (DSC) perfusion magnetic resonance imaging (MRI) can be used to evaluate posterior cerebral circulation in pediatric patients with moyamoya disease (MMD) who underwent anterior revascularization. Materials and Methods: This study retrospectively included 73 patients with MMD who underwent DSC perfusion MRI (age, 12.2 ± 6.1 years) between January 2016 and December 2020, owing to recent-onset clinical symptoms during the follow-up period after completion of anterior revascularization. DSC perfusion images were analyzed using a dedicated software package (NordicICE; Nordic NeuroLab) for the middle cerebral artery (MCA), posterior cerebral artery (PCA), and posterior border zone between the two regions (PCA-MCA). Patients were divided into two groups; the PCA stenosis group included 30 patients with newly confirmed PCA involvement, while the no PCA stenosis group included 43 patients without PCA involvement. The relationship between DSC perfusion parameters and PCA stenosis, as well as the performance of the parameters in discriminating between groups, were analyzed. Results: In the PCA stenosis group, the mean follow-up duration was 5.3 years after anterior revascularization, and visual disturbances were a common symptom. Normalized cerebral blood volume was increased, and both the normalized time-topeak (nTTP) and mean transit time values were significantly delayed in the PCA stenosis group compared with those in the no PCA stenosis group in the PCA and PCA-MCA border zones. TTPPCA (odds ratio [OR] = 6.745; 95% confidence interval [CI] = 2.665-17.074; P < 0.001) and CBVPCA-MCA (OR = 1.567; 95% CI = 1.021-2.406; P = 0.040) were independently associated with PCA stenosis. TTPPCA showed the highest receiver operating characteristic curve area in discriminating for PCA stenosis (0.895; 95% CI = 0.803-0.986). Conclusion: nTTP can be used to effectively diagnose PCA stenosis. Therefore, DSC perfusion MRI may be a valuable tool for monitoring PCA stenosis in patients with MMD.