• Title/Summary/Keyword: Software Quality-in-use

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Identification of CNVs and their association with the meat traits of Hanwoo

  • Chan Mi Bang;Khaliunaa Tseveen;Gwang Hyeon Lee;Gil Jong Seo;Hong Sik Kong
    • Journal of Animal Reproduction and Biotechnology
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    • v.38 no.3
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    • pp.158-166
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    • 2023
  • Background: Copy number variation (CNV) can be identified using next-generation sequencing and microarray technologies, the research on the analysis of its association with meat traits in livestock breeding has significantly increased in recent years. Hanwoo is an inherent species raised in the Republic of Korea. It is now considered one of the most economically important species and a major food source mainly used for meat (Hanwoo beef). Methods: In this study, CNVs and the relationship between the obtained CNV regions (CNVRs) can be identified in the Hanwoo steer samples (n = 473) using Illumina Hanwoo SNP 50K bead chip and bioinformatic tools, which were used to locate the required data and meat traits were investigated. The PennCNV software was used for the identification of CNVs, followed by the use of the CNV Ruler software for locating the different CNVRs. Furthermore, bioinformatics analysis was performed. Results: We found a total of 2,575 autosomal CNVs (933 losses, 1,642 gains) and 416 CNVRs (289 gains, 111 losses, and 16 mixed), which were established with ranged in size from 2,183 bp to 983,333 bp and 10,004 bp to 381,836 bp, respectively. Upon analyzing the restriction of minor alleles frequency > 0.05 for meat traits association, 6 CNVRs in the carcass weight, 2 CNVRs in the marbling score, 3 CNVRs in the backfat thickness, and 2 CNVRs in the longissimus muscle area were related to the meat traits. In addition, we identified an overlap of 347 CNVRs. Moreover, 3 CNVRs were determined to have a gene that affects meat quality. Conclusions: Our results confirmed the relationship between Hanwoo CNVR and meat traits, and the possibility of overlapping candidate genes, annotations, and quantitative trait loci that results depended on to contribute to the greater understanding of CNVs in Hanwoo and its role in genetic variation among cattle livestock.

Does Process Quality of Inpatient Care Serve as a Guide to Reduce Potentially Preventable Readmission (PPR)? (의료서비스의 과정적 질과 잠재적으로 예방 가능한 재입원율과의 관계)

  • Choi, Jae-Young
    • Korea Journal of Hospital Management
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    • v.23 no.1
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    • pp.87-106
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    • 2018
  • Objective: The objective of this study is to examine the association between process quality of inpatient care and risk-adjusted, thirty-day potentially preventable hospital readmission (PPR) rates. Data Sources/Study Setting: This was an observational cross-sectional study of nonfederal acute-care hospitals located in two states California and Florida, discharging Medicare patients with a principal discharge diagnosis of heart failure, acute myocardial infarction, or pneumonia January through December 31, 2007. Data were obtained from the Healthcare Cost and Utilization Project State Inpatient Database of the Agency for Healthcare Research and Quality, Centers for Medicare and Medicaid Services Hospital Compare database, and the American Hospital Association Annual Survey of Hospitals. Study Design: The dependent variable of this study is condition-specific, risk-adjusted, thirty-day potentially preventable hospital readmission (PPR). 3M's PPR software was utilized to determine whether a readmission was potentially preventable. The independent variable of this study is hospital performance for process quality of inpatient care, measured by hospital adherence to recommended processes of care. We used multivariate hierarchical logistic models, clustered by hospitals, to examine the relationship between condition-specific, risk-adjusted, thirty-day PPR rates and process quality of inpatient care, after taking clinical and socio-demographic characteristics of patients and structural and operational characteristics of hospitals into account. Findings: Better performance on the process quality metrics was associated with better patient outcome (i.e., low thirty-day PPR rates) in pneumonia, but not generally in two cardiovascular conditions (i.e., heart failure and acute myocardial infarction). Practical Implication: Adherence to the process quality metrics currently in use by CMS is associated with risk-adjusted, thirty-day PPR rates for patients with pneumonia, but not with cardiovascular conditions. More evidence-based process quality metrics closely linked to 30-day PPR rates, particularly for cardiovascular conditions, need to be developed to serve as a guideline to reduce potentially preventable readmissions.

A Ubiquitous Home Network System for Managing Environment-Information Sensors using Image Processing (영상 처리를 이용하여 주변 환경 센서를 관리하기 위한 유비쿼터스 홈 네트워크 시스템)

  • Hong, Sung-Hwa;Jung, Suk-Yong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.3
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    • pp.931-942
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    • 2010
  • A home network provides users with a variety of information services. The kind and quality of the services can be substantially enhanced by utilizing a variety of data from sensors. However, home networks currently limit their potential by focusing on providing multimedia services rather than services utilizing sensor data. Outdoor electronics are frequently made in a form that emphasizes only certain limited functions in contrast to home appliances. Thus, sensors with one or two functions rather than many can be used in outdoor systems and their use will be more economical than using sensor nodes indoors with more complex home appliances. In this study, we chose to work with motion sensors as they have many potential uses, and we selected a parking lot control system with to use the motion sensors. This parking lot control system was implemented and applied as part of a home network. For this purpose, we defined and implemented a protocol to manage the network in a ubiquitous sensor network environment for the wireless home network in this study. Although a network management system in a Ubiquitous Sensor Network (USN) related to this study is being advanced for other projects, the protocol interface and message system have not yet been clearly defined for use in a general purpose network or in an extension into heterogeneous kinds of networks, communication support, etc. Therefore, USN network management should be conducted for management of faults, composition, power, and applications. To verify the performance of the protocol interface designed in this study, we designed and implemented the necessary units (sensor nodes, sensor gateway, and server) for each network section and, with them, proved the validity of this study.

Development of Preliminary Quality Assurance Software for $GafChromic^{(R)}$ EBT2 Film Dosimetry ($GafChromic^{(R)}$ EBT2 Film Dosimetry를 위한 품질 관리용 초기 프로그램 개발)

  • Park, Ji-Yeon;Lee, Jeong-Woo;Choi, Kyoung-Sik;Hong, Semie;Park, Byung-Moon;Bae, Yong-Ki;Jung, Won-Gyun;Suh, Tae-Suk
    • Progress in Medical Physics
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    • v.21 no.1
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    • pp.113-119
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    • 2010
  • Software for GafChromic EBT2 film dosimetry was developed in this study. The software provides film calibration functions based on color channels, which are categorized depending on the colors red, green, blue, and gray. Evaluations of the correction effects for light scattering of a flat-bed scanner and thickness differences of the active layer are available. Dosimetric results from EBT2 films can be compared with those from the treatment planning system ECLIPSE or the two-dimensional ionization chamber array MatriXX. Dose verification using EBT2 films is implemented by carrying out the following procedures: file import, noise filtering, background correction and active layer correction, dose calculation, and evaluation. The relative and absolute background corrections are selectively applied. The calibration results and fitting equation for the sensitometric curve are exported to files. After two different types of dose matrixes are aligned through the interpolation of spatial pixel spacing, interactive translation, and rotation, profiles and isodose curves are compared. In addition, the gamma index and gamma histogram are analyzed according to the determined criteria of distance-to-agreement and dose difference. The performance evaluations were achieved by dose verification in the $60^{\circ}$-enhanced dynamic wedged field and intensity-modulated (IM) beams for prostate cancer. All pass ratios for the two types of tests showed more than 99% in the evaluation, and a gamma histogram with 3 mm and 3% criteria was used. The software was developed for use in routine periodic quality assurance and complex IM beam verification. It can also be used as a dedicated radiochromic film software tool for analyzing dose distribution.

Impacts of Nitrate in Base Flow Discharge on Surface Water Quality (질산성 질소 기저유출이 지표수 수질에 미치는 영향)

  • Kim, Geonha;Lee, Hosik
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.1B
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    • pp.105-109
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    • 2009
  • It is a well known fact that baseflow discharge of rainfall runoff impacts on water quality of surface water significantly. In this paper, impacts of nitrate discharged as base flow on stream water quality were studied by using a software, PULSE from USGS to calculate monthly ground water discharge from hydrograph. We used water quality and flow rate data for Ghapcehon2 site in Daejeon city for year 2005 as well as ground water quality data in the watershed acquired from government agencies. Agricultural and forestry land use are dominant for upstream of Ghapcheon2 in the watershed. Base flow contributes about 85~95% of stream flows during spring and fall while 25~38% of stream flow was induced by base flow during summer and winter. Monthly nitrate loading discharged as base flow for Ghapcheon2 was estimated by using averaged nitrate concentration of groundwater in the watershed. Nitrate loading induced by base flow at Ghapcheon2 was estimated as 5.4 ton of $NO_{3}{^-}-N/km^{2}$, which is about 60% of nitrate loading of surface water, 9.2 ton of $NO_{3}{^-}-N/km^{2}$. Seasonal variation of nitrate concentration of base flow was estimated by dividing monthly nitrate loading by monthly base flow discharge. Nitrate concentration of groundwater was increasing from rainy season. From this study, it can be understood that ground water quality monitoring is important for the proper manage of surface water quality.

An Audit Method on Information System Audit using Delphi Method - Based on Hyperledger Fabric (델파이기법을 이용한 감리점검항목 도출 방안 - 하이퍼레저 패브릭 기반으로)

  • Lee, Youngjoo;Park, Sooyong
    • Journal of Software Engineering Society
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    • v.29 no.2
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    • pp.7-12
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    • 2020
  • A project to establish an information system with a project cost of more than 500 million won at a local public firm is subject to the Information System Audit (hereinafter referred to as IS Audit), and the IS Auditor shall conduct audit according to the audit criteria. Recently, as blockchain technology has been applied to various fields such as manufacturing, healthcare, distribution, and public sectors beyond the financial industry, the development of systems that apply blockchain technology is increasing. The use of Hyperledger Fabric, a private blockchain, is on the rise to utilize blockchain technology in public firms and private firms. However, the newly emerging blockchain-based system is not sufficient to carry out auditing with existing audit check items, so it has no choice but to make and use audit items individually. Therefore, a need for verified audit items for systems that base on blockchain technology has emerged. In this study, we customized the Delphi process to derive audit items suitable for the system development project using the blockchain technology, and verified the completeness and accuracy of the audit items derived through a survey by the IS Auditor. This research will be of direct help to the IS Auditor, and it is expected that operators and organizers who provide services through the blockchain-based system will also contribute to improving the quality of the system.

A Study on Visual Communication Design for Effective Trial Presentation (효과적인 법정 프레젠테이션을 위한 비주얼커뮤니케이션 디자인 연구)

  • Baek, Se-Young
    • The Journal of the Korea Contents Association
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    • v.16 no.5
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    • pp.601-611
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    • 2016
  • As oral trial principle and civil participation in criminal trials spread, the environment of Korean courtroom is in need of a systematic introduction of trial presentation which can supplement with the oral trial presentation's weakness. Therefore this study analyzes the definition, types, and effectiveness of trial presentation, considering characters of the Korean court's environment. As for following research step, the most widely used trial presentation softwares in the USA and Korea are analyzed and compared in consideration of the particularity of the trial presentation. Based on this analysis, this study suggested elements to be included in the presentation software optimized for Korean court's environment as follows: 1. Ease of the insertion of various forms and media, 2. Appropriate limitation of the spectrum for graphic style, 3. Ease of use of graphics tools, 4. System functions. Such a suggestion was proposed not only to enhance the clarity, accuracy, effectiveness in developing insistence and delivery of content, but also promote aesthetic quality and consistency of presentation's visual communication aspect.

Analysis of 3D Building Construction Applications in Augmented Reality

  • Khan, Humera Mehfooz;Waseemullah, Waseemullah;Bhutto, Muhammad Aslam;Khan, Shariq Mahmood;Baig, Mirza Adnan
    • International Journal of Computer Science & Network Security
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    • v.22 no.10
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    • pp.340-346
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    • 2022
  • Construction industry is considered as one of the oldest industries in the world since human came into being and the need of their own space is realized. All this led to make the world a space of many beautiful constructive ventures. As per the requirements of today's world, every industry is recognizing the need for use and adoption of modern as well as innovative technologies due to their benefits and timely production. Now construction industry has also started adopting the use of modern and innovative technologies during their projects but still the rate of adoption is so slow. From design to completion, construction projects take a lot to manage for which technology based solutions have continuously been proposed. These include Computer Aided Design (CAD), building information modeling (BIM) and cloud computing have been proved to be much successful until now. The construction projects are high budgeted, and direly require timely and successful completion with quality, resource and other constraints. So, the researchers observe the need of more clear and technology based communication between the construction projects and its constructors and other stakeholders is required before and during the construction to take timely precautions for expected issues. This study has analyzed the use of Augmented Reality (AR) technology adopting GammaAR, and ARki applications in construction industry. It has been found that both applications are light-weighted, upgradable, provide offline availability and collaborative environment as well as fulfil most of the requirements of the construction industry except the cost. These applications also support different screen size for better visualization and deep understanding. Both applications are analyzed, based on construction's application requirements, usability of AR and ratings of applications user collected from application's platform. The purpose of this research is to provide a detail insight of construction applications which are using AR to facilitate both the future developers and consumers.

An Effective Data Analysis System for Improving Throughput of Shotgun Proteomic Data based on Machine Learning (대량의 프로테옴 데이타를 효과적으로 해석하기 위한 기계학습 기반 시스템)

  • Na, Seung-Jin;Paek, Eun-Ok
    • Journal of KIISE:Software and Applications
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    • v.34 no.10
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    • pp.889-899
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    • 2007
  • In proteomics, recent advancements In mass spectrometry technology and in protein extraction and separation technology made high-throughput analysis possible. This leads to thousands to hundreds of thousands of MS/MS spectra per single LC-MS/MS experiment. Such a large amount of data creates significant computational challenges and therefore effective data analysis methods that make efficient use of computational resources and, at the same time, provide more peptide identifications are in great need. Here, SIFTER system is designed to avoid inefficient processing of shotgun proteomic data. SIFTER provides software tools that can improve throughput of mass spectrometry-based peptide identification by filtering out poor-quality tandem mass spectra and estimating a Peptide charge state prior to applying analysis algorithms. SIFTER tools characterize and assess spectral features and thus significantly reduce the computation time and false positive rates by localizing spectra that lead to wrong identification prior to full-blown analysis. SIFTER enables fast and in-depth interpretation of tandem mass spectra.

Evaluation of Virtual Grid Software (VGS) Image Quality for Variation of kVp and mAs (관전압과 관전류량 변화에 대한 가상 그리드 소프트웨어(VGS) 화질평가)

  • Chang-gi Kong
    • Journal of the Korean Society of Radiology
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    • v.17 no.5
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    • pp.725-733
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    • 2023
  • The purpose of this study is to evaluate the effectiveness of virtual grid software (VGS). The purpose of this study is to evaluate the changes in energy and object thickness by dividing the use of VGS into two cases (Without-VGS) without using a movable grid. We attempted to determine the effectiveness of VGS by acquiring images using a chest phantom and a thigh phantom and analyzing SNR and CNR. In the chest phantom and femoral phantom, the tube flow was fixed at 2.5 mAs, and the tube voltage was changed by 10 kVp from 60 to 100 kVp to measure SNR and CNR, and SNR was about 1.09 to 8.86% higher in the chest phantom than in Without-VGS, and CNR was 4.18 to 14.56% higher in the VGS than in Without-VGS. And in the femoral phantom, SNR was about 9.78 to 18.05% higher in VGS than in Without-VGS, and CNR was 21.07 to 44.44% higher in VGS than in Without-VGS. The tube voltage was fixed at 70 kVp in the chest phantom and the femoral phantom, and the amount of tube current was changed at 2.5 to 16 mAs, respectively, and after X-ray irradiation, SNR and CNR were measured in the chest phantom, which was about 1.49 to 11.11% higher in VGS than in Without-VGS, and CNR was 4.76 to 13.40% higher in VGS than in Without-VGS. And in the femoral phantom, SNR was about 2.22 to 17.38% higher in VGS than in Without-VGS, and CNR was 13.85 to 40.46% higher in VGS than in Without-VGS. Therefore, if an inspection is required with a mobile X-ray imaging device, it is believed that good image quality can be obtained by using VGS in an environment where it is difficult to use a mobile grid, and it is believed that the use of mobile X-ray devices can be increased.