• Journal of the Korean Vacuum Society
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• v.16 no.1
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• pp.65-73
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• 2007

The control of surface properties and spatial presentation of functional molecules within a microfluidic channel is important for the development of diagnostic assays, microreactors, and for performing fundamental studies of cell biology and fluid mechanics. Here, we present soft lithographic methods to create robust microchannels with patterned microstructures inside the channel. The patterned regions were protected from oxygen plasma by controlling the dimensions of the poly(dimethylsiloxane)(PDMS) mold as well as the sequence of fabrication steps. The approach was used to pattern a non-biofouling polyethylene glycol(PEG)-based copolymer or the polysaccharide hyaluronic acid(HA) within microfluidic channels. These non-biofouling patterns were then used to fabricate arrays of fibronectin(FN) and bovine serum albumin(BSA) as well as mammalian cells.

• Smart Structures and Systems
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• v.13 no.1
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• pp.81-98
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• 2014

This paper presents the elastic buckling of smart lightweight column structures integrated with a pair of surface piezoelectric layers using artificial intelligence. The finite element modeling of Smart lightweight columns is found using $ANSYS^{(R)}$ software. Then, the first buckling load of the structure is calculated using eigenvalue buckling analysis. To determine the accuracy of the present finite element analysis, a compression study is carried out with literature. Later, parametric studies for length variations, width, and thickness of the elastic core and of the piezoelectric outer layers are performed and the associated buckling load data sets for artificial intelligence are gathered. Finally, the application of soft computing-based methods including artificial neural network (ANN), fuzzy inference system (FIS), and adaptive neuro fuzzy inference system (ANFIS) were carried out. A comparative study is then made between the mentioned soft computing methods and the performance of the models is evaluated using statistic measurements. The comparison of the results reveal that, the ANFIS model with Gaussian membership function provides high accuracy on the prediction of the buckling load in smart lightweight columns, providing better predictions compared to other methods. However, the results obtained from the ANN model using the feed-forward algorithm are also accurate and reliable.

• Journal of Magnetics
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• v.20 no.4
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• pp.444-449
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• 2015

Soft magnetic composites (SMCs) are especially suitable for the construction of low-cost, high-performance motors with 3-D magnetic fields. The main advantages of SMCs is that the iron particles are insulated by the surface coating and adhesive used for composite bonding, the eddy-current loss is much lower than that in laminated steels, especially at higher frequencies, and the hysteresis loss becomes the dominant component of core losses. These properties enable machines to operate at higher frequencies, resulting in reduced machine size and weight. In this paper, 3-D topologies are proposed that enable the application of SMCs to effectively reduce losses in high-speed permanent magnet (PM) motors. In addition, the electromagnetic field characteristics of the motor topologies are evaluated and compared using a non-linear finite element method (FEM) based on 3-D numerical analysis, and the feasibility of the motor designs is validated.

• The Plant Pathology Journal
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• v.32 no.2
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• pp.157-161
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• 2016

Gamma irradiation was evaluated for its in vitro and in vivo antibacterial activity against a postharvest bacterial pathogen, Erwinia carotovora subsp. carotovora (Ecc). Gamma irradiation in a bacteria cell suspension resulted in a dramatic reduction of the viable counts as well as an increase in the amounts of DNA and protein released from the cells. Gamma irradiation showed complete inactivation of Ecc, especially at a dose of 0.6 kGy. In addition, scanning electron microscopy of irradiated cells revealed severe damage on the surface of most bacterial cells. Along with the morphological changes of cells by gamma irradiation, it also affected the membrane integrity in a dose-dependent manner. The mechanisms by which the gamma irradiation decreased the bacterial soft rot can be directly associated with the disruption of the cell membrane of the bacterial pathogen, along with DNA fragmentation, results in dose-dependent cell inactivation. These findings suggest that gamma irradiation has potential as an antibacterial approach to reduce the severity of the soft rot of paprika.

• Geotechnical Engineering
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• v.10 no.2
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• pp.109-120
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• 1994

One of problems being faced during construction of soil structures along the coastal regions is the stabilization of soft clay foundation, In this study, centrifugal model bests were conducted to investigate behavior effect of soft foundation reinforced by cement -soil piles for the stabilization of softs clay foundation during the embankment construction. This paper presents results of settlement and heaving behavior of reinforced and unreinforced foundation with time under the swaged loading for different best conditions. The test results have shown that the reductions of vertical settlement of the foundation and heaving of the ground surface adjacent to the embankment are greatly influenced by strength of improved pile, and moisture content, and especially the ratio of replacement area.

• Journal of Navigation and Port Research
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• v.33 no.2
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• pp.119-125
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• 2009

The effect of plastic board drains (PBDs)on ground improvement was checked out considering three crucial factors: ground settlement, undrained shear strength, and residual water head. First, the settlement analysis including initial settlement induced by reclamation of sand mat was conducted by back calculation analysis with measured data. Its result showed toot the PBDs used for this site worked well on improving soft ground. Secondly, the undrained shear strength was investigated by laboratory and in-situ tests including unconsolidated-undrained triaxial compression (UU) tests, unconfined compression tests, in-situ vane tests, and cone penetration tests. From the test results, they showed that the undrained shear strength of the improved ground by PBDs was significantly increased as well as the strength increasing ratio especially $10{\sim}15m$ below the ground surface on site. Thirdly, the residual water head measurement from the in situ dissipation test was found the same as the static water head, which indicated primary consolidation was completed and the effect of soil improvement with PBDs can be confirmed.

• Journal of Microbiology and Biotechnology
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• v.33 no.12
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• pp.1692-1697
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• 2023

Staphylococcus aureus integrated with mecA gene, which codes for penicillin-binding protein 2a, is resistant to all penicillins and other beta-lactam antibiotics, resulting in poor treatment expectations in skin and soft tissue infections. The development of a simple, sensitive and portable biosensor for mecA gene analysis in S. aureus is urgently needed. Herein, we propose a dual-toehold-probe (sensing probe)-mediated exonuclease-III (Exo-III)-assisted signal recycling for portable detection of the mecA gene in S. aureus. When the target mecA gene is present, it hybridizes with the sensing probe, initiating Exo III-assisted dual signal recycles, which in turn release numerous "3" sequences. The released "3" sequences initiate catalytic hairpin amplification, resulting in the fixation of a sucrase-labeled H2 probe on the surface of magnetic beads (MBs). After magnet-based enrichment of an MB-H1-H2-sucrase complex and removal of a liquid supernatant containing free sucrase, the complex is then used to catalyze sucrose to glucose, which can be quantitatively detected by a personal glucose meter. With a limit of detection of 4.36 fM for mecA gene, the developed strategy exhibits high sensitivity. In addition, good selectivity and anti-interference capability were also attained with this method, making it promising for antibiotic tolerance analysis at the point-of-care.

• The Journal of Korean Society for Radiation Therapy
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• v.8 no.1
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• pp.41-54
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• 1996

The secondary electrons developed by interaction between primary beam and a tray mounted for blocks in Megavoltage irradiation result in excess soft radiation dose to the surface layer. To reduce this electron contamination, electron filters have been used to be attached under a tray. Various filters with Cu and Al plates in six different thickness and Cu/Al combined plates in 3 different thickness were tested to measure the reduction rate of secondary electron contamination to the surface layer. The measurement to find optimal filter was performed on 6MV linear accelerator in $10 cm{\times}10 cm$ field size and fixed 78.5cm source to measurement points distance from surface to maximum build up point in 2mm intervals. The result was analyzed as the ratio of measured doses with using filters, to standard doses of measured open beam. The result of this study was fellowing : 1. The contaminated low energy radiation were mainly produced by blocking tray. 2. The surface absorbed dose was slowly increased by increasing irradiation field size but rapidly increased at field size above $15cm{\times}15cm$. 3. Al plate upto 2.5mm thickness used as a filter was found to be inadequate due to the failure of reduction of the surface absorbed dose below doses of the under surface upto the maximal build up. Cu 0.5mm plate and Cu 0.28mm/A1 1.5mm compound plate were found to be optimal filters. 4. By using these 2 filters, the absorbed dose to the surface were effectively reduced $5.5\%$ in field size $4cm{\times}4cm,\;11.3\%$ in field size $10cm{\times}10cm,\;22.3\%$ in field size $25cm{\times}25cm$. 5. In field size $10cm{\times}10cm$, the absorbed dose to the surface of irradiation was reduced by setting TSD 20cm at least,. but effective and enough dose reduction could be achieved by setting TSD 30cm as 2 optimal filters used. 6. More surface dose absorbed at TSD less than 7.4cm with a tray and filters together indicated that soft radiation was also developed by filters. 7. The variation of PDD by the different size of irradiation field was minimal as 2 optimal filters used. There was also not different in variation of PDD according to using any of two different filters. 8. PDD was not effected either by various TSD or by using the different filter among two.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.48 no.4
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• pp.225-231
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• 2022

Objectives: This study aims to evaluate the efficacy and safety of two types of sandblasted with large-grit and acid-etched (SLA) surface implants with different surface roughness. Patients and Methods: This study was conducted based on a clinical record review of 55 patients (mean age, 53.00 years). A total of 80 SLA surface implants was placed. Among the 80 implants, 38 implants placed in 29 subjects had surface roughness (Ra) of 3.09 ㎛ (test group, TG), while the other 42 implants placed in 31 subjects had a surface roughness (Ra) of 2.50 ㎛ (control group, CG). A comparison was made of implant primary/secondary stability; success and survival rates; marginal bone loss; and soft tissue assessment including probing pocket depth (PPD), plaque index (PI), gingival index (GI), and bleeding on probing (BOP) between the groups at 1 year after implant placement. Results: Among the implants that were initially registered, 1 from the TG and 4 from the CG dropped out, leaving 37 implants in the TG and 38 implants in the CG to be traced and analyzed. Although 1 TG case showed unstable primary stability, all cases showed stable secondary stability. Success and survival rates at 1 year after implant placement were 100% in both groups. Marginal bone loss was 0.07 mm and 0.00 mm for the TG and CG, respectively, but the difference was not significant. Among the several parameters for evaluation of soft tissue, the TG showed lower PI at 1 year after implant placement (TG=0.00, CG=0.29; P=0.0004), while the remaining categories showed no significant difference between the groups. Conclusion: This study shows that the two types of SLA implants with different surface roughness have no difference in efficacy or safety. Therefore, both of the implants can be used safely and with promising outcomes.

• Applied Chemistry for Engineering
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• v.24 no.3
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• pp.219-226
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• 2013

Organic semiconductor-based soft electronics has potential advantages for next-generation electronics and displays, which request mobile convenience, flexibility, light-weight, large area, etc. Organic field-effect transistors (OFET) are core elements for soft electronic applications, such as e-paper, e-book, smart card, RFID tag, photovoltaics, portable computer, sensor, memory, etc. An optimal multi-layered structure of organic semiconductor, insulator, and electrodes is required to achieve high-performance OFET. Since most organic semiconductors are self-assembled structures with weak van der Waals forces during film formation, their crystalline structures and orientation are significantly affected by environmental conditions, specifically, substrate properties of surface energy and roughness, changing the corresponding OFET. Organo-compatible insulators and surface treatments can induce the crystal structure and orientation of solution- or vacuum-processable organic semiconductors preferential to the charge-carrier transport in OFET.