• Title/Summary/Keyword: Sodium hyaluronate

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Anti-irritation and Moisturizing Effects of Exopolysaccharide Produced by Grifola frondosa (잎새버섯이 생산하는 세포외 다당체의 보습력과 자극완화 효과)

  • Lee, Bum-Chun;Kim, Jin-Hwa;Bae, Jun-Tae;Lee, Dong-Hwan;Sim, Gwan-Sub;Pyo, Heong-Bae;Choe, Tae-Boo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.1 s.49
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    • pp.35-41
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    • 2005
  • We investigated the effects of skin hydration and anti-irritation of exopolysaceharide (GF-glucan) produced from submerged culture of Grifola frondosa. The moisturizing effects and trans-epidermal water loss (TEWL) of GF-glucan in cosmetic products (O/W emulsion) were clinically studied. GF-glucan showed good skin hydration effects when compared with sodium hyaluronate which is a commonly using moisturizer. The skin protective effects of GF-glucan against sodium lauryl sulfate (SLS) were also found. Twice a day application of the CF-glucan to skin reduced local inflammation remarkably. Irritant reactions were assessed by various aspects of skin function, erythema (skin color reflectance), hydration (electrical capacitance) and TEWL. In the human skin test, 5-day treatment of the GF-glucan was found to reduce SLS-induced skin erythema and Improve bier regeneration. Taken all together, GF-glucan should be a very useful cosmetic ingredient, as a moisturizer, and a protecting agent for various skin irritations.

Moisturizing Effects and Composition Analysis of Proteoglycan Isolated from Chia (Salvia hispanica) Seed (치아 씨앗으로부터 분리한 단백다당체의 성분분석과 보습 효과)

  • Lee, Bum-Chun;Joo, Chul-Gue;Hur, Ji-Yeon;Lee, Keun-Ha;Kim, Young-Jin;Lee, Chan-Woo;Kim, Jin-Woong;Park, Yong-Il;Kim, Hyun-Sook;Choe, Tae-Boo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.36 no.2
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    • pp.121-128
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    • 2010
  • We investigated the effects of skin hydration and composition analysis of proteoglycan (chia seed polymer) produced from chia (Salvia hispanica) seed. The result showed that proteoglycan of chia seeds is composed of galactose (46.8 %), glucuronic acid (27.1 %), rhamnose (8.7 %), xylose (7.6 %), glucose (4.9 %), fructose (2.3 %), mannose (1.8 %), arabinose (0.9 %) and the amount of proteins contained is 31.3 mg/g with the constituent amino acid compositions (mg/g) of Asp (1.9), Glu (3.6), Ser (0.9), Gly (3.6), Thr (0.8), Arg (1.0), Ala (2.0), Tyr (0.4), Cys (4.8), Val (1.1), Phe (0.5), Ile (0.6), Leu (0.9). The molecular weight of the proteoglycan measured by GPC (Gel Permeation Chromatography) is the range of 100,000~250,000 Da and the average molecular weight is 170,000 Da. The moisturizing effects and trans-epidermal water loss (TEWL) of chia seed polymer in cosmetic products (O/W emulsion) were studied in vivo. Chia seed polymer showed good skin hydration effects when compared with sodium hyaluronate which is a common moisturizer. Taken all together, chia seed polymer should be a very useful cosmetic ingredient as a moisturizer and a protecting agent from various skin irritations.