• 대한수의학회지
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• 제56권4호
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• pp.233-239
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• 2016

This study was conducted to analyze penicillin G (PEG), streptomycin (STR) and neomycin (NEO) residues in milk of healthy lactating cows. Milk samples were collected from all four quarters of 12 dairy cows 2−7 days after intramammary infusions of an ointment containing PEG, STR and NEO once (n = 4; group I) or twice (n = 4, group II) daily. Ultra-performance liquid chromatography coupled with electrospray tandem mass spectrometry was used to determine the antibiotic residues in the samples. The correlation coefficient ($r^2$) of the calibration curves for all antibiotics was > 0.999 and the limits of detection and quantification were $0.002-0.005{\mu}g/mL$ and $0.007-0.02{\mu}g/mL$, respectively. Recovery rates were ranged from 75.5 to 92.3%. In group I, PEG, STR and NEO residues were detected in milk at 2, 3 and 2 days post-treatment, respectively, which were below the maximum residue limit (MRL). In group II, PEG, STR and NEO residues were detected in milk at 2, 3 and 3 days post-treatment, respectively, which were bellow the MRL. These results suggest that a 3-day for milk withdrawal period after the ointment treatment might be sufficient for reduction of the antibiotic residues below the MRL.

• Journal of the Korean Data and Information Science Society
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• 제26권2호
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• pp.429-440
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• 2015

본 연구는 청소년 초기인 중학교 2학년 남녀학생의 BMI 정도에 따라 학교적응의 영향요인이 어떻게 다른지 확인하고자 시도되었다. 본 연구는 "한국청소년정책연구원"에서 제공한 '한국아동청소년 패널조사 (Korea Children and Youth Panel Study; KCYPS) 2010 중1 패널의 2차년도 데이터를 활용'하였다. 설명변수는 부모의 관심, 문제행동, 공격성, 주의집중 문제, 신체증상, 사회적 위축, 우울 및 학업성취도 (더미변수 처리)이다. 서술적 통계, 피어슨의 상관계수 및 다중회귀분석을 실시하였다. 회귀분석 결과, 남학생은 학업성취도 상이 공통된 영향요인이었으며, 설명력이 11.3 19.1%였다. 여학생은 주의집중 문제가 공통된 영향요인이었으며, 설명력이 14.9~42.4%였다. 학교적응의 영향요인들은 남녀학생의 BMI 정도에 따라 다르게 나타났다. 본 연구결과를 토대로 추후 중학생의 학교적응을 향상시키기 위해서는 BMI 정도에 따라 성별 특성에 맞춘 적응 증진 프로그램 개발이 필요하다.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2000년도 The 7th International Symposium
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• pp.34-51
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• 2000

Narcotic drugs generally refer to serious and habitual hidden rash such as opium, heroin, methyphetamin, nabinol, cocaine, and so forth. At present, narcotic drugs are spread unchecked and are causing a big social problem. So many countries and narcotists are making every effort to set up a barricade against narcotic drugs. And there is a limit suitable treatment for them. Thus Tuo Yin Tang hang is developed. As indicated by Chinese letters, Tuo yin Tang Jiang(TYTJ) is a crude drug. It is a traditional chinese medicine developed by the study done from lune in 1998 to lune in 1999 that Hubeisheng was entrusted with by People's Republic of China. This study is a treatise on etiology and syntomatology or narcotism. TYTJ is a medicine which is in accord with Pharmacopeia of the People's Republic of China in order to remove from the body the toxic materials resulting from narcotic drugs such as opium and heroin. According to the standard diagnosis on narcotism, 105 cases are studied and treated at the Rehabilitation Center attached to Enshi Autonomous Region Hospital in Hubeisheng. 105 cases are divided into 2 groups by double-blind method. One is the experimental group which has 56 cases. The other is the control group which has 49 ones. 13 cases among 105 cases are addicted by intravenously injections. 9 cases are by oral takings. It took 10 days for this experiment to be performed. Two groups didn't show a striking individual variation based on the age, gender, period of taking drugs, withdrawal symptoms, complication, and state of health. The experimental group had a higher effect of treatment than the control group had. TYTJ treats diseases effectively and has no side effect, irrespective of the serious or slight addiction to opium and morphine.

• 정신신체의학
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• 제5권1호
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• pp.118-122
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• 1997

저자들은 13년전 심한 산후 출혈 후에 서서히 진행된 성선, 갑상선, 부신피질호르몬결핍증상과 함께 피해망상, 환청과 이에 따른 행동, 심한 불면증, 정신운동의 지체, 사회적 철퇴 등의 증상을 보인 51세 여자환자의 증례를 경험하였다. 환자는 일견 심한 정신병적 우울증의 양상을 보여 정신과에 입원하였으나 자세한 병력 청취 및 임상양상의 관찰로 내과적 질환에 의한 정신증의 가능성이 고려되었고, 호르몬 검사상 범뇌하수체기능 부전소견과 저혈당증 및 저나트륨혈증 등을 나타내 Sheehan시 증후군의 진단이 가능하였다. 갑상선과 부신피질호르몬의 투여 기타 보존적인 치료에 의해 정신과적증상을 포함한 제반 임상증상이 1주이내에 호전되었다. 저자들은 본 증례의 보고를 통해 정신과 환자에 대한 임상적 접근에서 간과되기 쉬운 내재된 내과적 문제의 감별의 중요성을 다시 한 번 강조하고자 한다.

• Journal of Korean Biological Nursing Science
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• 제10권1호
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• pp.88-95
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• 2008

Purpose: The purpose of this study was to examine the effect of neuropathic pain by peripheral nerve injury on mass and Type I and II fiber cross-sectional areas on hindlimb muscles of the neuropathic pain model rat. Method: Adult male Sprague-Dawley rats (body weight 200-220 g) were assigned to one of two groups: a neuropathic pain group (n=7) that had a ligation of the left L5 spinal nerve, a control group (n=5), a naive rat without any procedures. Withdrawal threshold, activity, body weight and food intake were measured daily. At 8 days after neuropathic pain, all rats were anesthetized and the soleus and plantaris muscles were dissected from the both hindlimbs. Body weight, food intake, muscle weight and Type I and II fiber cross-sectional area of the dissected muscles were determined. Result: The neuropathic pain group showed a significant decreases (p<.05) as compared with the control rats, in diet intake, body weight, muscle weight and Type II fiber cross-sectional area of the left (affected side) soleus and plantaris muscles, and the right (unaffected side) muscle weight of plantaris and Type II fiber cross-sectional area of the soleus muscle. Conclusion: The hindlimb muscle atrophy occurs in both affected and unaffected side due to neuropathic pain by the peripheral nerve injury. The hindlimb muscle atrophy of the affected side is more pronounced than that of the unaffected side.

• 여성건강간호학회지
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• 제6권1호
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• pp.109-116
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• 2000

In modern society, the amount of alcohol ingestion is increasing at a dangerous level, especially among women. One of reason for increased alcohol consumption is stress caused by social pressures. Alcohol is a kind of depressant of centric nervous system, so it can induce relaxation of body and decrease the stress. The evidence on the effects of alcohol on the fetus is somewhat hazy, whereas that of smoking is quite clear. The literature on the ingestion of alcohol strongly suggests that drinking during pregnancy is associated with teratogenic effect and low birth weight. Therefore, the adverse effect of alcohol ingestion during pregnancy must be informed to public. More remarkable warning sign about alcohol ingestion must be attached on the top of bottles. This can be an effective measure for public education. Also legal sanction or tax imposition for the production of liquor be required. First of all, drinking habit or drinking culture must be changed. In fact, the strongest motivation of drinking in adolescent is a peer pressure which is related to drinking habit or culture. Secondly, early detection and treatment must be required to prevent from fetal alcohol syndrome. Accordingly, drinking history of pregnant women must be assessed as early as possible and health professional should give a warning about the abstinence of alcohol to drinking women. Thirdly, to minimize the adverse effects for mother, withdrawal syndrome by alcohol ingestion must be treated. to correct the malformation by fetal alcohol syndrome(FAS) can be corrected. Sometimes surgical intervention may be required for this purpose.

• 문화기술의 융합
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• 제5권1호
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• pp.185-191
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• 2019

스마트폰의 이용은 현대인의 생활에 편리함과 효율성을 증진시키나, 스마트폰이 없으면 일상생활을 하기 어려운 사용현상도 나타남으로써 개인의 정신건강을 위협한다. 특히 재난 및 화재에 노출되는 근무환경으로 인해 직무스트레스가 매우 높은 소방공무원의 스마트폰 사용현상은 이들의 개인적 안녕 및 직무수행에 매우 부정적인 영향을 미친다고 추측되어진다. 따라서 소방공무원들의 스마트폰 사용과 스트레스간의 관계에 대한 분석은 이들의 스트레스관리에 대한 문제점들을 살펴본다는 점에서 의미가 있다. 이 연구는 소방공무원의 스마트폰 사용 그리고 스트레스간의 관계 및 영향을 분석한다. 연구대상자는 총 230명이고 통계방법은 SPSS 20.2에 의한 집단별 분석(t-test와 ANOVA) 그리고 위계적 회귀분석을 사용하였다. 주요연구결과로는 소방공무원의 가구형태와 월수입이 스트레스에 유의미한 영향을 미쳤으며, 스마트폰 사용 하위요인 중 금단경험이 통계적으로 유의미한 영향을 미쳤다. 연구결과는 소방공무원의 스마트폰 사용에 대한 실증적 자료로 제공될 것이다.

• 문화기술의 융합
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• 제7권1호
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• pp.37-41
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• 2021

최근 ESG 투자는 전세계적으로 증가하고 있으며, 환경, 사회, 지배구조 등 ESG 위험성에 대한 인식이 높아지고 투자 결정시 이와 같은 비재무적 투자를 고려하는 추세이다. 최근 코로나19 사태를 겪으면서 환경에 초점이 맞추어지며 바이오와 헬스 관련 투자가 인기를 얻고 있는 반면 석탄 관련 사업 분야에서는 신규투자가 전면 중단되고 기존 사업은 순차적으로 사업을 종료하거나 철수하는 방향으로 의사결정이 이루어져 기후변화와 지속가능성을 투자 포트폴리오 최우선 순위로 설정하는 운용사가 증가하고 있다. 그 결과 투자환경 변화에 대한 효과적인 대응 방안을 제시하고, 리스크 관리체계의 구축에 도움이 될 수 있는 투자체계의 대응 및 준비에 노력을 기울일 필요가 있다. 따라서 동반성장과 호혜를 고려한 ESG 투자 동향을 간략히 살펴보고 시사점을 제시하고자 한다.

• 한국정보시스템학회지:정보시스템연구
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• 제30권4호
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• pp.21-42
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• 2021

Purpose In order for companies to continue to grow, they should properly manage human resources, which are the core of corporate competitiveness. Employee turnover means the loss of talent in the workforce. When an employee voluntarily leaves his or her company, it will lose hiring and training cost and lead to the withdrawal of key personnel and new costs to train a new employee. From an employee's viewpoint, moving to another company is also risky because it can be time consuming and costly. Therefore, in order to reduce the social and economic costs caused by employee turnover, it is necessary to accurately predict employee turnover intention, identify the factors affecting employee turnover, and manage them appropriately in the company. Design/methodology/approach Prior studies have mainly used logistic regression and decision trees, which have explanatory power but poor predictive accuracy. In order to develop a more accurate prediction model, XGBoost is proposed as the classification technique. Then, to compensate for the lack of explainability, SHAP, one of the XAI techniques, is applied. As a result, the prediction accuracy of the proposed model is improved compared to the conventional methods such as LOGIT and Decision Trees. By applying SHAP to the proposed model, the factors affecting the overall employee turnover intention as well as a specific sample's turnover intention are identified. Findings Experimental results show that the prediction accuracy of XGBoost is superior to that of logistic regression and decision trees. Using SHAP, we find that jobseeking, annuity, eng_test, comm_temp, seti_dev, seti_money, equl_ablt, and sati_safe significantly affect overall employee turnover intention. In addition, it is confirmed that the factors affecting an individual's turnover intention are more diverse. Our research findings imply that companies should adopt a personalized approach for each employee in order to effectively prevent his or her turnover.

• The Korean Journal of Pain
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• 제35권3호
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• pp.271-279
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• 2022

Background: Inflammation is known to underlie the pathogenesis in neuropathic pain. This study investigated the anti-inflammatory and neuroprotective mechanisms involved in antinociceptive effects of co-administration of acetaminophen and L-carnosine in chronic constriction injury (CCI)-induced peripheral neuropathy in male Wistar rats. Methods: Fifty-six male Wistar rats were randomly divided into seven experimental groups (n = 8) treated with normal saline/acetaminophen/acetaminophen + L-carnosine. CCI was used to induce neuropathic pain in rats. Hyperalgesia and allodynia were assessed using hotplate and von Frey tests, respectively. Investigation of spinal proinflammatory cytokines and antioxidant system were carried out after twenty-one days of treatment. Results: The results showed that the co-administration of acetaminophen and L-carnosine significantly (P < 0.001) increased the paw withdrawal threshold to thermal and mechanical stimuli in ligated rats compared to the ligated naïve group. There was a significant (P < 0.001) decrease in the levels of nuclear factor kappa light chain enhancer B cell inhibitor, calcium ion, interleukin-1-beta, and tumour necrotic factor-alpha in the spinal cord of the group coadministered with acetaminophen and L-carnosine compared to the ligated control group. Co-administration with acetaminophen and L-carnosine increased the antioxidant enzymatic activities and reduced the lipid peroxidation in the spinal cord. Conclusions: Co-administration of acetaminophen and L-carnosine has anti-inflammatory effects as a mechanism that mediate its antinociceptive effects in CCI-induced peripheral neuropathy in Wistar rat.