• 한국가금학회지
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• 제38권2호
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• pp.145-154
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• 2011

By a series of positional cloning, we successfully narrowed down the AM candidate region to approximately 1.2 Mbp on GGA2q including 7 functional genes. Subsequently, we identified WWP1 gene as the most likely AM candidate by sequence comparison. The amino acid sequence around the candidate mutation was highly conserved among tetrapods, suggesting that WWP1 is the causative gene of chicken muscular dystrophy. Transfection of mutated WWP1 gene into $C_2C_{12}$ myoblasts disrupted muscle differentiation process. The abnormal muscle differentiation is a characteristic of chicken muscular dystrophy, so we could demonstrate a part of phenotype of the disease. Furthermore, western blotting revealed that accumulation of caveolin-3 protein is limited in damaged muscle of muscular dystrophic chicken, suggesting caveolin-3 may be associated with the pathological change of the disease. We could conclude that WWP1 gene is the responsible one for chicken muscular dystrophy from these results, but the mechanism leading the onset should be clarified in the future. The information will contribute to the study of chicken muscular dystrophy and the corresponding human dystrophies.

• Journal of Applied Biological Chemistry
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• 제43권3호
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• pp.141-146
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• 2000

Glycosidase activities were tested from the grape berries, Vitis labruscana B. Takasumi. Among various glycosidases, $\alpha$-D-galactosidase was found to be the most active in the flesh and other glycosidases were considerably active in the order of the following: $\alpha$-D-mannosidase>$\alpha$-D-glucosidase>$\beta$-D-glucosidase>$\beta$-D-galactosidase. In the seeds, $\alpha$-D-glucosidase activity was the highest and other glycosidases such as $\alpha$-D-galactosidase, $\beta$-D-glucosidase, and $\beta$-D-galactosidase were still significantly active. The $\alpha$-D-galactosidase in the grape flesh was purified over 83-folds through salting-out with $(NH_4)_2SO_4$ and a series of chromatographies employing Sephadex G-50, Octyl-Sepharose, Q-Sepha- rose, and Biogel P-100. The enzyme was a monomer of 45 kDs as determined through SDS-PAGE and Sephacryl S-200 chromatography. The purified enzyme showed a preference of $\alpha$-D-galactose to $\beta$-D-galactose as a substrate about 5.4 times. Sulfhydryl specific reagents such as N-ethylmaleimide and iodoacetamide significantly inhibited the enzyme activity to the extents of 48 and 52% of its initial activity, respectively. The optimumpH range of $\alpha$-D-galactosidase was around 6.5-7.0. The enzyme activity increased by 46% in the presence of 1mM $Fe^{2+}$.

• 간호행정학회지
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• 제13권2호
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• pp.184-190
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• 2007

Purpose: This study was undertaken in order to suggest self-leadership as a method for nurses to lower their job stress and enhance their job satisfaction. So the relations among self-leadership, job stress and job satisfaction were studied. Method: The subjects of study were 123 nurses who have been working in 2 general hospitals located in K city. The data were collected by Q & A and analyzed using descriptive statistics, Pearson's correlation coefficient, t-test, and ANOVA on SPSS Program. Result: Nurses got average 3.50, 2.64 and 3.12 points out of 5 in their self-leadership, job stress and job satisfaction respectively. The self-leadership was negatively correlated with job stress (r=-.429, p=<.001) while it is positively correlated with job satisfaction(r=.281, p=<.001). And job stress was negatively correlated with job satisfaction(r=-.574, p=<.001). Job stress had statistically significant differences according to age and marital status. Conclusion: In conclusion self-leadership is correlated with job stress and job satisfaction. It is recommend that hospital managers have to develop methods which enhance self-leadership of nurses.

• Journal of Information Technology Applications and Management
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• 제14권3호
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• pp.179-197
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• 2007

This paper analyzed the effects of interactions among participants on the satisfaction and commitment of cyber education. Even if the quality of interactions in cyber education may not be so good as that of interactions in face to face education. various kinds of interactions could be introduced in cyber education. An email or Q/A between lecturer and students could be a good way to compensate the deficiency of cyber education. Common News Boards or Discussion Rooms among students themselves are also a powerful means to learn each other in cyber space. The result of this study shows that as interactions among participants increase. satisfaction and commitment of the lecture also increase. This study also analyzed how cyber educational effects differs as interaction type changes in space dimension and time dimension. The result shows interactions in the same cyber space such as News Board brings more desirable outcome than those in the different cyber space. But the effects of interactions classified by time dimension does not show statistically significant differences.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2000년도 하계학술대회 논문집 C
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• pp.1927-1929
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• 2000

PD indicates the inception and progress of degradation of solid insulation system, so it has been used to determine degradation of insulation. PD provides means for detection and recognition of defects. However, there is still marked difficult to recognize defects by PD methods. In this paper, we investigated properties of PD in solid insulation by using statistical method with surface discharge, electrical tree and void discharge with source of discharge, we used statistical parameters of PD distributions specified such as $H_n(q)$, $H_{an}(\phi)$, $H_n(\phi)$, $H_a(\phi)$. The parameters induced from its specified distributions are average discharge, average repetition rate, Skewness, Kurtosis, asymmetry and correlation. From the parameters, we classified PD patterns and built up DB(data-base).

• 제어로봇시스템학회논문지
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• 제22권12호
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• pp.995-1001
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• 2016

The vehicle suspension system plays a very important part related with vehicle ride and handling. To improve the vehicle ride and handling many researches have been progressed from various damping parameter tuning techniques to the development of the electronic controlled suspension systems. In this paper, as one of the ride performance improvement a disturbance observer(DOB) based control system is applied to the quarter car vehicle model in order to show that the DOB can obtain good vibration isolation characteristics. First, the robust stability criterion for the DOB is introduced in detail, and then how DOB is applied to the 1/4 car vehicle model is represented, and finally to confirm the effectiveness of the DOB in vehicle ride performance improvement a computer simulation is carried out for various driving conditions.

• 전자공학회논문지
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• 제54권2호
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• pp.146-150
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• 2017

OFDM 시스템 앙상블의 대역외 방사는 인접 앙상블의 수신성능에 영향을 주기 때문에 대역외 방사 완화기법의 적용은 매우 중요한 기술에 해당한다. 본 논문에서는 DAB 계열 OFDM시스템 스펙트럼의 대역외 방사 완화 기법과 관련하여 시간영역 윈도윙 방식을 적용한 대역외 방사 완화 기법 적용을 고찰하여 보았으며, 해당 기법을 T-DMB (DAB 모드-1) 및 AT-DMB 향상계층 B-모드 및 Q-모드에 대하여 적용한 결과 약 3dB 정도의 대역외 방사 완화 이득을 얻었다. 또한 BER 성능 측정에서도 해당 기법을 적용함에 따른 성능 저하가 매우 미미함을 확인하였다.

• Journal of Plant Biology
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• 제19권2호
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• pp.49-61
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• 1976

A survey was conducted on the vegetation of Judo and Gamagseum in warm temperate zone of Southern Korea. They are covered with natural vegetation, evergreen forest dominated with Castanopsis cuspiadata in Judo and Machilus thunbergii in Gamagseum. Judo is a small island, ca. 1.75 ha, located within the Wando port. Since the flora of Wando including the Judo was reported in 1924, some investigator have reported evergreen trees of Judo. But the list of plant species of Judo is still unavailable. Gamagseum, located at the 15km morth of Judo, is a small island, ca. 1.45 ha, cosisting of two islands, Dae-o-do and So-o-do in low tide, and the report of its flora and any other survery on its is almost none. The vegetatons of Judo and Gamagseum are an example of natural forest vegetation occured rarely in warm temperate zone because of human disturbance in the southern coast zone of the Korean Peninsula. However, the ecological study of those vegetation has not ever been made, and the ecological or plant geographical situations of their vegetation is not clear. To determine the vegetation type, listing of plant species in the islands, calculation of basal area of trees over DBH=4.5cm, Raunkiaer's life form, leaf size class, Pte.-Q and etc., were studied. Total plant species of Judo was 110 species and that of Gamagseum was 99 species. In Judo, Castanopsis cuspidata was 1384 individuals among 2359 individuals over DBH=4.5cm, and in Gamagseum, Machilus thunbergii was remarkably abundant and Castanopsis cuspidata could not be found.

• Structural Engineering and Mechanics
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• 제24권2호
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• pp.213-225
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• 2006

The propagation of non-uniformly modulated, evolutionary random waves in viscoelastic, transversely isotropic, stratified materials is investigated. The theory is developed in the context of a multi-layered soil medium overlying bedrock, where the material properties of the bedrock are considered to be much stiffer than those of the soil and the power spectral density of the random excitation is assumed to be known at the bedrock. The governing differential equations are first derived in the frequency/wave-number domain so that the displacement response of the ground may be computed. The eigen-solution expansion method is then used to solve for the responses of the layers. This utilizes the precise integration method, in combination with the extended Wittrick-Williams algorithm, to obtain all the eigen-solutions of the ordinary differential equation. The recently developed pseudo-excitation method for structural random vibration is then used to determine the solution of the layered soil responses.

• Mycobiology
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• 제37권2호
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• pp.133-140
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• 2009

To optimally convert corn hull, a byproduct from corn processing, into bioethanol using Pachysolen tannophlius, we investigated the optimal conditions for hydrolysis and removal of toxic substances in the hydrolysate via activated carbon treatment as well as the effects of this detoxification process on the kinetic parameters of bioethanol production. Maximum monosaccharide concentrations were obtained in hydrolysates in which 20 g of corn hull was hydrolyzed in 4% (v/v) $H_2SO_4$. Activated carbon treatment removed 92.3% of phenolic compounds from the hydrolysate. When untreated hydrolysate was used, the monosaccharides were not completely consumed, even at 480 h of culture. When activated carbon.treated hydrolysate was used, the monosaccharides were mostly consumed at 192 h of culture. In particular, when activated carbon-treated hydrolysate was used, bioethanol productivity (P) and specific bioethanol production rate ($Q_p$) were 2.4 times and 3.4 times greater, respectively, compared to untreated hydrolysate. This was due to sustained bioethanol production during the period of xylose/arabinose utilization, which occurred only when activated carbon-treated hydrolysate was used.