• Journal of Genetic Medicine
• /
• v.14 no.2
• /
• pp.62-66
• /
• 2017

Interchromosomal insertion of Y chromosome heterochromatin in an autosome was identified in a fetus and a family. A fetal karyotype was analyzed as 46,XX,dup(7)(?q22q21.1) in a referred amniocentesis at 16 weeks of gestation for advanced maternal age. In the familial karyotype analyses for identification of der(7), the mother, the first daughter and the maternal grandmother showed the same der(7) as the fetus's. CBG-banding was positive at 7q22 region of der(7) that indicated inserted material was originated from heterochromatin. The origin of heterochromatic insertion region in der(7) of the fetus and the mother was found in Yq12 region by fluorescent in situ hybridization with a DYZ1 probe. In the specific analysis of Y chromosomal heterochromatic region of ins(7;Y) of the mother, 15 sequence tagged sites from Yp11.3 region including SRY to Yq11.223 region was not detected. Final karyotypes of the mother, the first daughter and the maternal grandmother were reported as 46,XX,der(7)ins(7;Y)(q21.3;q12q12). All female carriers of ins(7;Y) in the family showed normal phenotype and the mother and the maternal grandmother were fertile. A healthy girl was born at term. We report a rare case of familial interchromosomal insertion of Y chromosome heterochromatin detected only in female family members with normal phenotype that was diagnosed prenatally.

• Journal of Convergence for Information Technology
• /
• v.10 no.6
• /
• pp.1-7
• /
• 2020

The demand on the underwater communications is extremely increasing in searching for underwater resources, marine expedition, or environmental researches, yet there are many problems with the wireless communications because of the characteristics of the underwater environments. Especially, with the underwater wireless networks, there happen inevitable delay time and spacial inequality due to the distances between the nodes. To solve these problems, this paper suggests a new solution based on ALOHA-Q. The suggested method use random NAV value. and Environments take reward through communications success or fail. After then, The environments setting NAV value from reward. This model minimizes usage of energy and computing resources under the underwater wireless networks, and learns and setting NAV values through intense learning. The results of the simulations show that NAV values can be environmentally adopted and select best value to the circumstances, so the problems which are unnecessary delay times and spacial inequality can be solved. Result of simulations, NAV time decreasing 17.5% compared with original NAV.

• Journal of Hospice and Palliative Care
• /
• v.17 no.4
• /
• pp.278-288
• /
• 2014

Purpose: The purpose of this study is to analyze types of shared medical decision making by health professionals in a decision making position. Methods: The Q-methodology was used. Q sample was constructed with a total of 35 Q-statements that were offered with a 9-point rating scale. The statements were structured to generate answers that would form a shape of a normal distribution. Answers to Q sample were analyzed using a QUANL PC program. Results: Four types of shared medical decision making were identified. Type I is patient-centered decision making, Type II is physician-centered, Type III is health professional-centered and Type IV is patient-family-centered. Conclusion: Study results indicate that it is recommended to develop an education program based on the four types of shared medical decision making so that health professionals can be provided with different approaches according to their decision making style.

• Clinical and Experimental Pediatrics
• /
• v.48 no.12
• /
• pp.1389-1389
• /
• 2005

The long arm duplication of chromosome 3 was reported for the first time in 1966 by Falek et al., and Hirschhorn et al. came to identify the duplication of 3q21${\rightarrow}$qter region in 1973. In most cases of duplication 3q syndrome patients, pure duplication of 3qter is believed to be rare and is often reported accompanied with deletion of another segment of the chromosome. Approximately 75 percent of parents of the patient in the meantime have been demonstrated to have unbalanced translocations or inversions of the chromosome. Partial deletion of the distal part of the short arm of chromosome 3 was first reported by Verjaal and De Nef in 1978 and terminal deletion of chromosome 3 (3p25-qter) has been observed in most cases. In karyotyping of chromosomes of immature infants showing the manifestations of flat occiputs, low set ears, hypertelorism, broad nasal roots, thin lips, web necks, hypotonia, hypertrichosis skin, cryptorchidism etc, we experienced a case diagnosed as 46,XY, rec(3)dup(3)(q21)del(3)(p25)inv(3)(p25q21).

• Journal of Korean Academy of Nursing
• /
• v.22 no.3
• /
• pp.389-406
• /
• 1992

This study was designed to identify nursing students' attitudes toward life through a Q-methodology. A Q-sample was formed through a review of the literature and interviews(n＝160)l The final Q-sample consisted of 37 statements out of an initial 100 statements after consultation with an expert panel and pilot testing. The P-sample consisted of 14 university nursing students and 27 junior college nursing students, which was selected by convenience sampling method. Data were analyzed by the Q-analysis method. The correlation between type 2 and type 3 was relatively high (r＝0.539) ; that between type 1 and type 3 was lowest (r＝0.014). The first type of attitude was the “rational utilitarian” type. Students in this type valued life relative to the quality of life. They agreed with euthanasia and artificial abortion if the quality of life was threatened. The criteria for their judgement were scientific knowledge and rationality. The second type of attitude was the “Christian deontologic” type. These students appreciated the sanctity of life according to Christian dogma. They disagreed with euthanasia and artficial abortion. And they disagreed strongly that life should be created by scientific development, because only God creates life. The third type of attitude was the “unconditional deontologic” type. These students agreed with the sanctity of life, not from Christian belief but from belief in the sanctity of life. The final type of attitude was the “prima facie(conditional) deonologic” type. These students appreciated the value of life and humanity. They expressed concern for others' life and suffering. They do not want to afflict others with their own miseries. This group showed a dual value system toward themselves and others. So they experience conflict between their concern for their on and others' conditions. These nursing students' values may have been influenced by their clinical experience in hospitals and other nursing fields. Through this study, we may realize the importance of education in nursing ethics for discussion of ethical conflicts and to support ethical nursing practice.

• Journal of Oriental Neuropsychiatry
• /
• v.19 no.2
• /
• pp.1-14
• /
• 2008

Objective : This study was designed for find corelation between behavior and physical symptoms in child. Physical symptoms appearing related with weak viscera are selected. And behaviors related to selected symptoms are compared that of children with character type defined by jung, c. G. Method: 497 children ( 3-11 years old ) who have visited two oriental clinic ( one is in Gang-Nam Gu Seoul (282 children), the other is in Joong-Rang Gu Seoul (215 children) ) from Jan. to Jul. 2006 were invested through the questionnaires, which were filled by their parents. These questionnaires have 61 yes-no type questions about behaviors on 12 situations, 36 yes no type questions about physical symptoms in 15 categories. 6 questions expected positive answer in child with weak spleen are categorized sp-q and 6 related weak lung, lu-q, 6 related weak kidney, ki-q. Numbers of positive answers in sp-q, lu-q and ki-q are counted so-index, lu-index and ki-index each. Corelation between behavior questions and 3 symptom indexes are measured and questions shown low significance level ( under 5% in pearson corelation, two-tailed ) are selected. Result: 15 behaviors related sp-index, 12 related lu-index, 12 related ki-index are selected and analysed. Conclusion : 1. Behaviors related sp-index is similar to that of Thinking Type children Grouped by jung, c. G.. 2. Behaviors related lu-index is similar to that of Sensation Type. 3. Behaviors related sp-index is similar to that of Feeling Type.

• Journal of Genetic Medicine
• /
• v.12 no.1
• /
• pp.49-56
• /
• 2015

We herein report an analysis of a female baby with a de novo dup(10p)/del(10q) chromosomal aberration. A prenatal cytogenetic analysis was performed owing to abnormal ultrasound findings including a choroid plexus cyst, prominent cisterna magna, and a slightly medially displaced stomach. The fetal karyotype showed additional material attached to the terminal region of chromosome 10q. Parental karyotypes were both normal. At birth, the baby showed hypotonia, upslanting palpebral fissures, a nodular back mass, respiratory distress, neonatal jaundice and a suspicious polycystic kidney. We ascertained that the karyotype of the baby was 46,XX,der(10)($pter{\rightarrow}q26.3::p11.2{\rightarrow}pter$) by cytogenetic and molecular cytogenetic analyses including high resolution GTG-and RBG-banding, fluorescence in situ hybridization, comparative genomic hybridization, and short tandem repeat marker analyses. While almost all reported cases of 10p duplication originated from one of the parents with a pericentric inversion, our case is extraordinarily rare as the de novo dup(10p)/del(10q) presumably originated from a rearrangement at the premeiotic stage of the parental germ cell or from parental germline mosaicism.

• Journal of the Korean Data and Information Science Society
• /
• v.26 no.6
• /
• pp.1465-1477
• /
• 2015

In Korea, the word, 'Literary Therapy' can be replaced by 'Bibliotherapy', 'Journal Therapy', 'Writing Therapy', 'Poem Therapy', 'Integrated Literary Therapy', or 'Imaginary-Oriented Poetry Therapy', and so on. This study, intended on people related to literary therapy, uses Q-methodology as useful research method of objectifying abstract concepts which can be perceived differently according to individual experience or perception, to investigate types of literary therapy's subjective perceptions. The result of study can be analyzed by four types: The first type is 'Pursuing Generalization', the second type is 'Considering the Therapist', the third type is 'Emphasizing the Integration', and the forth type is 'Maximizing the literary therapy'. Through this result of the study, we can find the responsibility of literary therapy as a leader of cultural, artistic therapy to break down various pathological situations which contemporary society have.

• Journal of the Institute of Electronics Engineers of Korea TC
• /
• v.45 no.6
• /
• pp.27-33
• /
• 2008

Given a polynomial ${\hbar}(x){\in}F_q[x]$ of degree h, it is an important problem to determine the size of multiplicative subgroup of $\(F_q[x]/({\hbar(x))\)*$ generated by $x-s_1,\;x-s_2,\;{\cdots},\;x-s_n$, where $\{s_1,\;s_2,\;{\cdots},\;s_n\}{\sebseteq}F_q$, and for all ${\hbar}(x){\neq}0$. So far the best known asymptotic lower bound is $(rh)^{O(1)}\(2er+O(\frac{1}{r})\)^h$, where $r=\frac{n}{h}$ and e(=2.718...) is the base of natural logarithm. In this paper, we exploit the coding theory connection of this problem and prove a better lower bound $(rh)^{O(1)}\(2er+{\frac{e}{2}}{\log}r-{\frac{e}{2}}{\log}{\frac{e}{2}}+O{(\frac{{\log}^2r}{r})}\)^h$, where log stands for natural logarithm We also discuss about the limitation of this approach.

• Journal of fish pathology
• /
• v.34 no.2
• /
• pp.261-269
• /
• 2021

This study presents the evaluation of sample extraction and purification procedure for the determination of residues of febantel and its metabolites, fenbendazole, oxfendazole and oxfendazole sulfone in rockfish (Sebastes schlegeli) muscle using liquid chromatography-tandem mass spectrometry. Residues of febantel and its metabolites in rockfish muscle were analyzed using each different sample preparation method from Korean Food Standards Codex (KFSC), Food Safety and Inspection Service (FSIS, USA), and the modified FSIS method using QuEChERS kit (FSIS-Q), respectively. Each method was compared for mean recoveries and repeatabilities. Since FSIS-Q showed higher repeatabilities (coefficient of variation, CV of 2.4%~10.9%) than those of FSIS method (CV of 4.6%~17.5%), recoveries from FSIS-Q were compared with those from KFSC method. FSIS-Q showed significantly higher recoveries of 83.1%~110.1% (P < 0.05) than those from KFSC method of 64.7%~107.4%. In addition, FSIS-Q showed a good linearity over the range of 2.5~200 ㎍/kg, and excellent sensitivities with limit of detection of 0.46~0.71 ㎍/kg and limit of quantification of 1.08~2.15 ㎍/kg. Although all the sample preparation methods turned out to be able to meet CODEX guideline for all the compounds, FSIS method and FSIS-Q validated in this study could be applied to screening and quantification for residues of febantel and its metabolites in rockfish muscle with efficient preparation procedures.