• Journal of Korean Neurosurgical Society
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• 제29권12호
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• pp.1584-1591
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• 2000

Objective : Until now, it has been little known about the biological mechanisms associated with the genesis, growth, and rupture of intracranial aneurysm. This study was performed to investigate and understand a part of these mechanisms. Materials and Methods : Immunohistochemical stains for angiogenesis growth factors(basic fibroblast growth factor (bFGF) and vascular endothelial growth factor(VEGF)) and selected vascular wall matrix proteins(alpha smooth muscle actin(${\alpha}SMA$) and collagen Type IV) were performed in fixed sections from a normal circle of Willis artery which was taken from the autopsy specimen as a control vessel and 17 aneurysmal wall specimens which was taken during surgical clipping of aneurysms. The staining intensity and distribution of immunoreactivity to angiogenesis growth factors and selected wall matrix proteins in control vessel and aneurysmal wall were examined and compared with each other. The difference of staining intensity according to the size of aneurysm was also investigated. Results : There was no immunoreactivity to bFGF and VEGF in the control vessel. bFGF immunoreactivity was exhibited in 15 of 17 aneurysm specimens around smooth muscle cells within the media of aneurysm. VEGF immunoreactivity was also exhibited in all aneurysm specimens in patches or diffusely affecting all layers of the aneurysmal wall. The degrees of intensity of bFGF and VEGF immunoexpression were proportionate roughly to the size of aneurysm. Strong immunoexpression of both factors were noticed in large aneurysm. A regularly arranged and defined band of immunoreactivity of ${\alpha}SMA$ was noticed in the media of the control vessel, whereas diffuse, faint, irregularly arranged ${\alpha}SMA$ was noticed in the aneurysmal wall. A regularly defined band of collagen Type IV immunoreactivity was also noticed in the subendothelium of the control vessel, whereas diffuse disorganized immunoreactivity of collagen Type IV was noticed in the entire wall of the aneurysm. Conclusion : These results indicate substantial evidences of abnormal expression of angiogenesis factors and changes of selected vascular wall matrix proteins in the wall of intracranial aneurysm. The unbalanced changes of angiogenesis factors and vascular wall matrix proteins in the wall of aneurysm may be one of the biological mechanisms for the growth and rupture of aneurysm.

• 한국정밀공학회지
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• 제33권7호
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• pp.541-549
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• 2016

Rolling contact fatigue and wear on rails are inevitable in railway operations due to excessive wheel-rail contact stress. The wear is influenced by vehicle speed, contact pressure, environmental conditions, and many other factors. Speeding on a curved track causes many problems such as wear on the gauge of the rail and rolling contact fatigue. Managing environmental conditions can reduce problems on the wheel and rail interface. In this study, the wear characteristics of wheel and rail materials were investigated by twin-disc testing using various parameters. The results of the wear test indicated that the wear rate under dry conditions was larger than that under wet conditions. We found that contact fatigue damage occurred on the rail in dry conditions, however, the surface of the specimen under water remained smooth. Also, the friction coefficient in dry conditions was larger than in wet conditions.

• 대한기계학회논문집
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• 제12권2호
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• pp.278-285
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• 1988

본 연구에서는 SM15C재와 SM35C재에 퍼얼라이트, 페라이트 조직의 영향을 배재한 비교적 균질한 조직인 구상화시멘타이트조직과 SM35C재에 실용조직 이면서 비교적 균질한 조직인 마르텐사이트 조직을 만들고, 가공하였다.

• 한국세라믹학회지
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• 제46권1호
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• pp.94-101
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• 2009

The physical properties of artificial aggregates made from clay and inorganic wastes with poor plasticity depends largely on forming method. The artificial aggregates composing of coal fly ash, stone sludge and clay were fabricated using 4 different forming methods and those physical properties were comparatively analyzed. The surface of aggregates made through the extrusion forming process was dense and smooth but was rough for the aggregates obtained by crushing a tile-shaped green body. The aggregates made by pelletizing process had a weak green strength and bumpy surface. The shell generated at surface during a high temperature sintering process induced the most aggregates to be bloated due to a dense shell. But the aggregates made through pelletizing process with dense surface layer showed no significant change in bulk density with sintering temperatures. The water absorption of aggregates decreased with sintering temperature, and that of pelletized specimen was standing $1.8{\sim}2.2$ times higher than that of made by other forming methods. It is concluded that the aggregates having various properties could be fabricated from one batch by using different forming methods.

• 한국가시화정보학회지
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• 제12권1호
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• pp.49-53
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• 2014

In this study, a novel FDR-SPC is first synthesized in this study. The drag reducing functional radical such as PEGMA (Poly(ethylene) glycol methacrylate) has been utilized to participate in the synthesis process of the SPC. The types of the baseline SPC monomers, the molecular weight and the mole fraction of PEGMA were varied in the synthesis process. The resulting SPCs were coated to the substrate plates for the subsequent hydrodynamic test for skin friction measurement. In a low-Reynolds number flow measurement using PIV (Particle Image Velocimeter), a significant reduction in Reynolds stress was observed in a range of specimen, with the maximum drag reduction being 15.9% relative to the smooth surface.

• 한국정밀공학회지
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• 제7권3호
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• pp.75-82
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• 1990

Automatic monitoring of the cutting conditions is one of the most improtant technologies in machining. In this study, the feasibility in applying acoustic emission(AE) signals for the in-process detection of endmill wear and fracture has been investigated by performing experimental test on the NC vertical milling machine with SM45C for specimen. As the results of detecting and analyzing AE signals on various cutting conditions, the followings have confirmed. (1) The RMS value of acoustic emission is related sensitively to the cutting velocity, but is not affected largely by feed rate. (2) The burst type AE signals of high level have been observed when removing chips distorderly and discontinuously. (3) When the RMS value grows up rapidly due to the increase of wear the endmill are generally broken or fractured, but when the endmills fracture at the conditions of smooth chip-flow or built-up-edge(BUE) occurred frequently, the rapid change of the RMS arenot found. And it is expected that this technigue will be quite useful for in-process sensing of tool wear and fracture.

• Journal of Welding and Joining
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• 제4권1호
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• pp.47-57
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• 1986

The elastic-plastic fracture toughness J_{Ic}$ of submerged arc welded structural steel $SB_{41}$ which has the properties of low strength and high ductility was discussed, especially paying attention to a comparison between two methods recommended by ASTM and JSME. $J_{IC}$ tests were carried out with compact specimens by means of R-curve, SZW, ultrasonic and electric potential methods. Based on the investigations in this study, the results obtained are as follows; (1) The JSME R-curve method gave the smallest $J_{IC}$ values which were physically closest to the crack initiation and seemed to be more practical and stable procedure between the two R-curve methods. (2) The JSME SZW method tended to slightly overestimate the $J_{IC}$ values at initiation of ductile tearing. (3) The ultrasonic and electric potential methods which also had a tendency to overestimate these $J_{IC}$ values were confirmed to be applicable and useful in determining these values. (4) The $J_{IC}$ values by the JSME R-curve method were 18.06 kgf/mm and 17.25kgf/ mm for the smooths and the side grooved CT specimen respectively.

• Journal of Welding and Joining
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• 제6권4호
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• pp.16-26
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• 1988

The effect of carbon content on hot cracking of welded carbon steel was investigated Eight steel plates whose carbon content range from 0.02 to 0.23 percent were welded by autogeous gas tungsten are process. Constant strain was applied to the hot crack test specimen under the strain rate of 0.15 mm per second during welding. The hot cracking susceptibility ws high in the rnage of 0.02-0.05 and 0.12-0.23 percent carbon contents. The critical carbon content immune to hot cracking is in the range from 0.07 to 0.12 percent carbon. By electron probe microanalyser, amanganese segregation was not seen significantly in the whole carbon range. But segregation of silicon was higher in the region of low carbon contents. However, sulphur was segregated remarkably in the region betwen 0.18 and 0.23 percent carbon by peritectic reaction. Very smal lamount of dnedritic structure was observed in the region from 0.02 to 0.05 percent carbon by peritectic reaction. Very small amount of dendritic structure was observed in the region from 0.02 to 0.05 percent carbon but the predominant solidification structure was smooth by cellular growth. The higher the carbon content is, the more the columnar dendritic structure was observed.

• 대한세포병리학회지
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• 제3권1호
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• pp.12-18
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• 1992

It is very rare to diagnose a squamous cell carcinoma when the carcinoma cells are observed in various body fluids. The effusion cytology of squamous cell carcinoma has not been sufficiently studied till now. We examined 10 cases of body fluid cytologic specimen diagnosed as metastatic squamous ceil carcinoma, which were selected among 2,100 body fluid cytology cases collected from 1986 to 1991. The patients had been confirmed to have primary squamous ceil carcinomas. The backgrounds of cellular aspirates were necrotic in most and the cells appeared in clusters or individually. The cell clusters showed round and smooth margins, mimicking adenocarcinoma, but in flat sheets rather than three-dimensional bails. the individual cells were most frequently Graham's 3rd-type cells, found in all cases, which were described as 1.5 times large as the parabasal cells and having small cytoplasmic rims. Other malignant squamous cells were undifferentiated cells, polygonal cells, fiber cells, and tadpole cells with decreasing order of frequency. The recognition of various features of malignant squamous cells would be helpful for the diagnosis of squamous ceil carcinoma found in effusion cytology.

• Journal of Chest Surgery
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• 제11권3호
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• pp.246-252
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• 1978

A three year and seven month old girl with moderate depression deformity of the sternum associated with a huge well defined homogenous hazy mass density of the upper half of the right hemithorax on plain chest x-ray had developed, exertionaI dyspnea (Figs1, 2 and 3). Correction of the funnel chest was carried out with modified Ravitch procedure and resection of the intrathoracic cystic mass was performed through an anterolateral thoracotomy incision in one stage operation satisfactorily (Figs. 7 and 8). On exploration, the mass, $15{\times}12{\times}10$cm in size, was connected to the bronchus at 1cm a bove the carina by a stalk (Fig. 4). The outer surface showed abundant vasculature. The specimen was filled with mucoid material; the inner surface was much trabeculated. glistening and smooth (Fig. 5 and 6). yficroscopically, the cyst was lined with simple or pseudostratified ciliated columnar epithelium. The cystic wall was composed of loose fibrous connective tissue, muscle layers, cartilages with some lymphocytic infiltration (Fig. 9). Isolated cases of funnel chest deformity and congenital bronchogenic cystic disease are not uncommon; however, the assocbtion of the two conditions is yery rare. Therefore. report and review of the literature was done.