• Korean Journal of Oriental Medicine
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• v.16 no.1
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• pp.29-41
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• 2010

The smallpox or chanjin(瘡疹), from Korea Dynasty when the name concretely is discussed to Joseon Dynasty, was very one of the diseases which were important. Not only the public but also the royal family could not avoid the pain which is caused by with the smallpox. Also as a scar and fear that the smallpox leave on, the smallpox was called a God(痘瘡神). As the prayer and sacrificial rites primarily could not relieve the nation and the community from a smallpox, an intellectual finally had to remind that if people considered a factor which caused the smallpox, they could cure this disease. That was Nam Hyoon(南孝溫) who rejected a goast to cause a smallpox. And the compilation of "Changjinjip(瘡疹集)" changed recognition about a smallpox. Especially, the compilation of "Changjinjip" was very important in the history of Korean medicine. Because it told what "Uibanglyuchui(醫方類聚)" the national compilation project of medicine book that King Sejong promoted leaved. The "Changjinjip(瘡疹集)" adopted two kind methods. The one was the medical history or with medical theoretic history method: arranged a various medical theory about "changjin" like "Uibanglyuchui". The other was the clinical method of presenting theories and prescriptions as causes and mutations: reformed contents of "Uibanglyuchui". In addition to special medicine book of smallpox, "Changjinjip" gave knowledge about a paradigm of "Uibanglyuchui" and methods of medical book compilation in later.

• Journal of the military operations research society of Korea
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• v.29 no.2
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• pp.26-44
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• 2003

This study Is to forecast the damage of smallpox as a biological weapon and to measure the effect of potential responses (quarantine, vaccination and cure) to the spread of smallpox infection when a smallpox bioterrorism attack occurs. We designed the smallpox spreading simulation model through the literature study on a basis of some existing infectious disease models such as SIR, SEIR model by using Vensim program. In order to evaluate the performance of responses to smallpox, we measure the total infection population, infection sustaining duration, average infection rate and the infection spreading behavior of the smallpox. This study can help those who are related to the bioterrorism forecast the present and possible demage, and take more effective actions for minimizing the damage by smallpox bioterrorism.

• The Journal of Korean Medical History
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• v.30 no.2
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• pp.119-131
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• 2017

GogeumGyeongheomHwalyubang [古今經驗活幼方] is a medical book dedicated to Smallpox, written by YU Sang [柳瑺] in the Joseon Dynasty (late 17th century to the early 18th century). As a smallpox specialist for the Joseon royal family, YU Sang was well-reputed after successfully treating smallpox of three of the 27 Joseon kings. There are four features of this book. First, the causes for smallpox are roughly recorded. Second, YU Sang emphasized the distinction between patients who could or could not be cured. Third, the herbs related to the treatment of smallpox are selected and organized separately. Fourth, YU Sang discusses the contents of diverse medical books and his own experiences. Conclusion : YU Sang's significant knowledge of smallpox treatment is well presented in his book, GogeumGyeongheomHwalyubang and this wealth of experience would have an important role in understanding the development of smallpox treatment in the late Joseon Dynasty.

• Journal of Haehwa Medicine
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• v.19 no.2
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• pp.1-12
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• 2011

21th century is a era of new pandemic. We are facing a new challenge and need a new way of approach. But eastern medicine and western medicine is clinging to their own way and have no intention to hear other one's opinion. Before the invention of the vaccination, smallpox has always been a major problem. Intellectuals in every country tried their best to find the treatment for the smallpox, and for Europian, didn't hesitate to borrow some knowledge of the pagon. Romans adopted the Galens concept, running away from the epidemic lesion. Christianity made smallpox Saints, and later adopted Razes heat therapy. But in the 17th century, these methods didn't turn out well, so they needed a new way of approach. By this movement, they had adopted the Chinese inoculation concept and invented a vaccination, By studying the effort of the Europian intellectuals who had tried their best to find the treatment for the smallpox until 17th century, we might get a glimps of wisdom which they had shown us. By this paper we can feel the passion to learn new techniques and their open mind and courage, which might be also needed in the 21th century, era of new pandemic.

• The Journal of Korean Medical History
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• v.25 no.1
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• pp.43-51
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• 2012

Smallpox and measles might be the typical epidemics through Choson Danasty. Especially Sookjong was the first king who suffered from smallpox during the period of his reign. This study was examined critically focused on the Clinical Records about Smallpox which occurred in the 9th year of Sookjong's reign. The clinical records in Seungjeongwon Ilgi("承政院日記") was the main source and the Annals of the Joseon Dynasty was reffered. It tells us that Sookjong caught infectious disease, smallpox spread in town and the whole process of smallpox. Seungmagalgeuntang(升麻葛根湯) and hwadoktang(火毒湯) were given at the early term for treating Sookjong's smallpox, but later on, Bowontang(補元湯) was given for the treatment of smallpox. It showed us the medical view which placed emphasis on the vital force of human body. A dermatologist, Yoo Sang had joined since the beginning of the treatment and Siyakchung(侍藥廳) was established for Sookjong. Sasunghoichuntang(四聖回天湯) which was Chunyoohyung(全有亨)'s prescription showed us enough clinical experience and the ways of treatments. At the same time, the medical culture at that time was well known through the fact that smallpox was taboo among the royal family.

• The Journal of Korean Medical History
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• v.15 no.2
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• pp.45-58
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• 2002

Appearance of a new disease can be seen as a raising a question to the established medicine system. If the problem can not be solved, the established medicine system becomes a degenerating program. So, the process of discovering the nature of a disease and giving a medical explanation was studied focused on smallpox. When smallpox was infected in the begining, many were killed especially mortality of young people were high. It is a general process of contagious diseases known as an epidemic. When the plague is prevalent continuously, it comes to stay and becomes a pediatric disease called smallpox. Time of discovering the nature of smallpox and giving a medical explanation and the time that came to stay are correspondant. This process of medical explanation is a dialectical process.

• The Journal of Korean Medical History
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• v.30 no.1
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• pp.1-9
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• 2017

Although Maejeong-Bogam (梅亭寶鑑) is a manuscript, it has attracted considerable attention from academia because of the clear authorship and relevant treatment methodologies. This article is the result of an extensive study on the author and the contents of the manuscript through the use of various data. This article revealed facts which include: 1) Author HAN Bangryeol (韓昉烈) is a Confucian doctor who lived in Namwon area, Jeolla province of Korea. 2) Dr. HAN's other manuscript of Bongseong-Shinbang (鳳城神方) was written before 1814. 3) Maejeong-Bogam (梅亭寶鑑) collects pediatric medical records only and is focused on outbreaks and treatment of smallpox among children. 4) Smallpox was a national concern in the late Joseon Dynasty and doctors of the day developed corresponding therapies. 5) Smallpox Inoculation was carried out in Jeolla Province as early $19^{th}$ in Korea.

• Microbiology and Biotechnology Letters
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• v.50 no.4
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• pp.457-464
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• 2022

A public health concern emerging from a zoonotic disease. Monkeypox is caused by the orthopoxvirus specie Monkeypox virus (MPXV). Monkeypox was identified as the most common orthopoxvirus infection in humans following the eradication of smallpox. Monkeypox has a similar clinical presentation to smallpox. The MPXV is now considered a high-threat pathogen that causes a serious public-health problem. The continuous spread of Monkeypox virus from West Africa to all other places around the world throughout 2018 to 2022, have raised concerns that MPXV could have emerged to acquire the immunological and ecological niche vacated by smallpox virus. This review highlights the current knowledge about Monkeypox evolution, infection biology, and epidemiology around the world since from 1970 to 2022, with a focus on the human, viral, and cellular factors that influence virus emergence, infection, spread, and maintenance in nature. This paper also discusses the current therapeutic options for Monkeypox treatment and control. Under the right conditions, with limited smallpox vaccination and very little orthopoxvirus immunity in some areas of the world, MPXV could become a more efficient human pathogen. Finally, the review identified knowledge gaps, particularly in terms of identifying a definitive reservoir host for monkeypox and proposes future research endeavors to address the unanswered questions.

• Journal of Korean Medical classics
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• v.29 no.4
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• pp.37-52
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• 2016

Objectives : The paper seeks to delve into a study of smallpox, specifically as one of the most representative contagious diseases during the Chosun era and how it was treated during that time. The lack of traditional medical texts that deal with smallpox has led this paper to dive into Duchanggyeongheombang. Methods : Everything related to edition and copy, and the author was organized based on pre-existing studies. The copy that is assumed as the original copy was considered and studied. The book was compared to and reviewed with Donguibogam, and the differences between the book and Korean translation were given attention as well. Results : Park Jin-hee is assumed to have authored Duchanggyeongheombang, and it is like that was had access to texts published by the state, one of which includes Donguibogam. He utilized the periods with smallpox outbreaks as his frame of study and put together a series of treatment for different symptoms. To this, he attached various medical charts, and added Korean translation for higher usability. In his book, he placed emphasis on spleen and stomach, but when needed, he did not shy away from using cold and coolness herbs. Conclusions : Duchanggyeongheombang was influenced partially by Donguibogam, but the book was given new life through the author Park Jin-hee's edition. Medical charts were added to increase its usability, and Korean translation was provided for wider audience. Its scope of prescription is very wide, and it provided the reasonings behind its medical judgements based on actual clinical studies instead of being tied down to traditions or taboos.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.22 no.12
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• pp.881-890
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• 2010

As Influenza A virus(H1N1) has been spreading more rapidly around globe, the study on the airborne disease which is transimitted through the respiratory system is on the rise. In this study, the multizone simulation of the public building against bioviolence is performed in the case of unexpected spread of microbial contaminants, such as bioviolence agent, Influenza A, Smallpox, B. anthrax and transport and control characteristics of above three kinds of bioviolence agents are evaluted. Results suggest that Influenza A and Smallpox which has small mean diameter can be more removable than B. anthrax by using high UVGI grade condition and B. anthrax which has large mean diameter can be more removable than Influenza A and Smallpox by using high filter grade condition. Results also suggest that installing a combined air treatment system is more effective to reduce the damage and engineers will use immune building technology for removing the bioviolence agents effectively.