• BMB Reports
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• v.49 no.6
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• pp.303-304
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• 2016

Myoblast fusion is important for skeletal muscle formation. Even though the knowledge of myoblast fusion mechanism has accumulated over the years, the initial signal of fusion is yet to be elucidated. Our study reveals the novel function of a phosphatidylserine (PS) receptor, stabilin-2 (Stab2), in the modulation of myoblast fusion, through the recognition of PS exposed on myoblasts. During differentiation of myoblasts, Stab2 expression is higher than other PS receptors and is controlled by calcineurin/NFAT signaling on myoblasts. The forced expression of Stab2 results in an increase in myoblast fusion; genetic ablation of Stab2 in mice causes a reduction in muscle size, as a result of impaired myoblast fusion. After muscle injury, muscle regeneration is impaired in Stab2-deficient mice, resulting in small myofibers with fewer nuclei, which is due to reduction of fusion rather than defection of myoblast differentiation. The fusion-promoting role of Stab2 is dependent on its PS-binding motif, and the blocking of PS-Stab2 binding impairs cell-cell fusion on myoblasts. Given our previous finding that Stab2 recognizes PS exposed on apoptotic cells for sensing as an "eat-me" signal, we propose that PS-Stab2 binding is required for sensing of a "fuse-me" signal as the initial signal of myoblast fusion.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.21 no.7
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• pp.1013-1020
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• 1997

Among various gyroscopes, the vibrating gyroscope has advantages such as compact size, mass-productivity and low cost. However this kind of gyroscope usually suffer from low linearity and low signal to noise ratio. Therefore, it is necessary to study on vibrating gyroscope to improve performance. In this paper, triangular cross section si selected in consideration for several points. The existing designs of exciting and sensing have some problems such that small signal size and low linearity. This paper proposes new design of exciting and sensing which is named one period exciting and the other period sensing. This design improves signal size, but it cannot improve linearity. This is because above two designs are the same open-loop type. So, another new design is proposed, which is named rebalancing, is applied to one period exciting and the other period sensing. This design are closed-loop type. It feedbacks the output signal. According to control theory, it can improve linearity. The circuits of each design are realized and used to calibration test. Calibration results show that new design of rebalancing improves linearity and signal size.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.5 no.7
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• pp.1287-1294
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• 2001

As size of waveform is very small, ECG(electrocardiogram) signal is difficult to analyze for noise which is occurred when it measures. In order to obtain ECG clearly, it must eliminate that power line interference, baseline wandering, noise of muscle constriction. In ECG, the worst problem which is recorded signal of ECG is the baseline wandering elimination, which is occurred by rhythm of respiration and muscle constriction of part from attaching to an electrode. Such the baseline is roughly irregular wandering and shaking up and down therefore the part of the baseline wandering elimination is very important because it is difficulty of ECG diagnosis. In this study, as implementation of real-time signal processing digital filter it is applicable to analyze patient's heart disease by way of design of the baseline wandering elimination system.

• Proceedings of the KIEE Conference
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• 1999.11c
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• pp.742-744
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• 1999

In this paper, a new precharge type PFD for fast locking time of PLL is suggested. It is realized by inserting NMOS transistor and inverter into the precharge part of PFD for isolating the reset of the Up signal from the feedback signal. The new precharge type PFD generates the Up signal while the feedback signal is fixed at a high level. Therefore the new PFD output is increased than the conventional precharge type PFD output. As a result of the increased PFD output, fast locking of PLLs is achieved. Additionally, with control the falling time of the inverter, the dead-zone is reduced and the jitter characteristics are improved. The whole characteristics of PFD and PLL are simulated by using HSPICE. Simulation results show that the dead-zone is 20ps and the locking time of PLL using the new PFD is 38ns at the 350MHz frequency of referecne signal. This value is quite small compared with conventional PFD.

• Journal of the Optical Society of Korea
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• v.18 no.6
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• pp.657-662
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• 2014

We demonstrate a simulation of a parallel hybrid fiber amplifier in the C+L-band with a gain controlling technique. A variable optical coupler is used to control the input signal power for both EDFA and RFA branches. The gain spectra of the C+L-band are flattened by optimizing the coupling ratio of the input signal power. In order to enhance the pump conversion efficiency, the EDFA branch was pumped by the residual Raman pump power. A gain bandwidth of 60 nm from 1530 nm to 1590 nm is obtained with large input signal power less than -5 dBm. The gain variation is about 1.06 dB at a small input signal power of -30 dBm, and it is reduced to 0.77 dB at the large input signal power of -5 dBm. The experimental results show close agreement with the simulation results.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.14 no.6
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• pp.2634-2648
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• 2020

In this paper, an adaptive sparse singular value decomposition (ASSVD) algorithm is proposed to estimate the signal matrix when only one data matrix is observed and there is high dimensional white noise, in which we assume that the signal matrix is low-rank and has sparse singular vectors, i.e. it is a simultaneously low-rank and sparse matrix. It is a structured matrix since the non-zero entries are confined on some small blocks. The proposed algorithm estimates the singular values and vectors separable by exploring the structure of singular vectors, in which the recent developments in Random Matrix Theory known as anisotropic Marchenko-Pastur law are used. And then we prove that when the signal is strong in the sense that the signal to noise ratio is above some threshold, our estimator is consistent and outperforms over many state-of-the-art algorithms. Moreover, our estimator is adaptive to the data set and does not require the variance of the noise to be known or estimated. Numerical simulations indicate that ASSVD still works well when the signal matrix is not very sparse.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.15 no.2
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• pp.99-104
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• 2015

This paper proposes the RMMA (Region based Multiple Modulus Algorithm) algorithm that is possible to improving the performance of MMA adaptive equalization algorithm in order to the reduction of intersymbol interference occurs at the communication channel. In RMMA algorithm, the output constellation of equalizer are divided by 4 different regions in order to get the error signal for adapting the channel characteristic, and the small error signal is obtained by mapping each region to 4-QAM signal. The conversion effect of constant modulus from nonconstant modulus signal was obtained. In this paper, the adaptive equalization performance of proposed RMMA were evaluated comared to the present MMA. As a result of computer simulation, the convergence speed and residual quantity were improved in residual isi and MD. Especially the superiorities of robustness was confirm in SER performance compared to present MMA.

• Journal of Electrical Engineering and Technology
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• v.9 no.1
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• pp.334-343
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• 2014

In this paper, we suggest a method to improve the fusion of an accelerometer and gyro sensor by using a Kalman filter to produce a more high-quality respiration signal to supplement the weakness of using a single accelerometer. To evaluate our proposed algorithm's performance, we developed a chest belt-type module. We performed experiments consisting of aerobic exercise and muscular exercises with 10 subjects. We compared the derived respiration signal from the accelerometer with that from our algorithm using the standard respiration signal from the piezoelectric sensor in the time and frequency domains during the aerobic and muscular exercises. We also analyzed the time delay to verify the synchronization between the output and standard signals. We confirmed that our algorithm improved the respiratory rate's detection accuracy by 4.6% and 9.54% for the treadmill and leg press, respectively, which are dynamic. We also confirmed a small time delay of about 0.638 s on average. We determined that real-time monitoring of the respiration signal is possible. In conclusion, our suggested algorithm can acquire a more high-quality respiration signal in a dynamic exercise environment away from a limited static environment to provide safer and more effective exercises and improve exercise sustainability.

• 정보저장시스템학회:학술대회논문집
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• 2005.10a
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• pp.190-194
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• 2005

There is a great demand of micro-actuators for mobile information devices such as SFF optical drives and mobile camera phones. However, conventional magnetic coils of electromagnetic motors are a major obstacle for miniaturization because of their complicated structures and large power consumption. In this paper, a linear ultrasonic motor to actuate focusing lens of mobile devices is proposed. The new actuator uses a ring type bimorph piezoelectric material, and $d_{31}$ mode is adopted for applying linear motion. The interaction between inertia force and friction force makes linear motion by high-frequency saw signal input. The saw signal gives steady forces on the one direction by asymmetric inclination property of the signal itself on time domain. A commercial FEM (ANSYS) was used in this investigation for simulating structural analysis, identification of dynamic property, such as resultant displacement and coupled analysis with piezoelectric material. To evaluate the performance of the new design, a prototype was manufactured and experiments were carried out. Experimental results show the actuator motion of 1.52 mm/s at 10 kHz input signal in 5 V.

• Transactions of the Society of Information Storage Systems
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• v.2 no.4
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• pp.251-256
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• 2006

There is a great demand of micro-actuators for mobile information devices such as SFF optical drives and mobile phone cameras. However, the magnetic coils used in conventional electromagnetic motors are a major obstacle for the miniaturization because of their complicated structures and large power consumption. In this paper, a linear ultrasonic motor to actuate focusing lens of mobile devices is proposed. The new actuator uses a ring type bimorph piezoelectric material, and $d_{31}$ mode is adopted for applying linear motion. The interaction between inertia force and friction force makes linear motion by high-frequency saw signal input. The saw signal gives steady forces on the one direction by asymmetric inclination property of the signal itself on time domain. A commercial FEM(ANSYS) was used in this investigation for simulating structural analysis, identification of dynamic property, such as resultant displacement and coupled analysis with piezoelectric material. To evaluate the performance of the new design, a prototype was manufactured and experiments were carried out. Experimental results show the actuator motion of 5.4 mm/s at 10V saw signal of 41 kHz.