• Genomics & Informatics
• /
• v.9 no.1
• /
• pp.39-43
• /
• 2011

MicroRNAs (miRNAs) are recently discovered small RNA molecules usually resulting in translational repression and gene silencing. Despite the fact that specific cloning of small RNA's is a method in practice, computational identification of miRNA's has been a major focus recent days, since is a rapid process following AB initio and sequence alignment methods. Here we developed new software called MiRPI that aims to identify the highly conserved miRNAs without any mismatches from given fasta formatted gene sequences by using non-repeated miRNA dataset of the user's interest. The new window embedded with the software is used to identify the targets for inputted mature miRNAs in the mRNA sequences. Also MiRPI is designed to measure the precursor miRNA statistics, majorly focusing the Adjusted Minimum Folding free Energy (AMFE) and Minimum Folding free Energy Index (MFEI), the most important parameters in miRNA confirmation. MiRPI is developed by PERL (Practical Extraction and Report Language) and Tk (Tool kit widgets) scripting languages. It is user friendly, portable offline software that works in all windows OS, sized to 3 MB.

• Genomics & Informatics
• /
• v.9 no.2
• /
• pp.74-78
• /
• 2011

Numerous restraints and simplifications have been developed for methods that anticipate protein structure to reduce the colossal magnitude of possible conformational states. In this study, we investigated if globularity is a general characteristic of proteins and whether they can be applied as a valid constraint in protein structure simulations with approximated measurements (Gb-index). Unexpectedly, most of the proteins showed strong structural globularity (i.e., mode of approximately 76% similarity to the perfect globe) with only a few percent of proteins being outliers. Small proteins tended to be significantly non-globular ($R^2$=0.79) and the minimum Gb-index showed a logarithmic increase with the increase in protein size ($R^2$=0.62), strongly implying that the non-globular characteristics might be more acceptable for smaller proteins than larger ones. The strong perfect globe-like character and the relationship between small size and the loss of globular structure of a protein may imply that living organisms have mechanisms to aid folding into the globular structure to reduce irreversible aggregation. This also implies the possible mechanisms of diseases caused by protein aggregation, including some forms of trinucleotide repeat expansion-mediated diseases.

• Proceedings of the Korean Powder Metallurgy Institute Conference
• /
• 2006.09a
• /
• pp.39-40
• /
• 2006

The relationship between the powder particle size change and a mechanical property of the Metal Injection Molding (MIM) product was examined in detail. The XRD results indicate that the diffraction peaks of BCC appeared in compacts of powder particle size of 4 to $10{\mu}m$ as well as the bulk SUS630. However, the diffraction peaks from both BCC and FCC were observed in the compact with powder size less than $3{\mu}m$. TEM observation revealed that the powder with those BCC/FCC two phase structure have a finely dispersed $SiO_2$ precipitates. Because the Si is ferrite stabilizing element, decrease of Si composition in the matrix phase by the $SiO_2$ precipitation resulted in formation of the retained austenite. Therefore, controlling the elements such as Si as well as oxygen decrease is very important to obtain a normal microstructure in ultra-fine powder $(<3{\mu}m)$ injection molding.

• The Journal of Asian Finance, Economics and Business
• /
• v.8 no.10
• /
• pp.77-85
• /
• 2021

This study aims to investigate the status quo and identify the challenges and benefits of the digital transformation in the context of small and medium-sized enterprises (SMEs) in Vietnam. The six participating SMEs were purposely contacted, and they were either nominated for, or received the Vietnam Digital Awards in 2018, 2019 and 2020, which were held by the Vietnam Digital Communication Association (http://en.vdca.org.vn/). A qualitative research method is adopted, using a semi-structured interview method and a theoretical triangulation of legitimacy, stakeholder and stewardship theories to facilitate the investigation. This research tries to identify the current challenges and benefits for digital transformation of SMEs in Vietnam, based on perception and experience from business leaders and managers from six SMEs in Vietnam. The findings of this study reveal that besides the recent challenges for digital transformation, participants also experienced and shared their perspectives regarding the benefits received from the digital transformation journey of their organization, which varied from (i) improve operational as well as business functions; (ii) liberate staffs and managers from daily work and allows them to focus on decision-making tasks; (iii) enable solutions to deal with consequences from the COVID-19 pandemic; (iv) enhance value creation process; and (v) help firms to align with the global business standards.

• The Journal of Asian Finance, Economics and Business
• /
• v.8 no.2
• /
• pp.329-338
• /
• 2021

The mobile payment system has not only changed the payment pattern but also has improved the performance of small and medium-sized enterprises (SMEs) and individuals' quality of life by saving their energy, reducing the risk of taking cash, and enabling them to give more time to businesses and do international business. Besides, with the current advancement in the Internet as well as the digital transformation, SMEs are being forced to adopt mobile payment systems (MPS). The purpose of this study is to investigate the effects of technological-organizational-environmental (TOE) determinants on the adoption of MPS and its impact on SMEs' firm performance operating in Ghana. This research employed a closed-ended questionnaire to collect data from January 2020 - April 2020. This study used a structural equation modeling (SEM) approach using SmartPLS 3.0 for path analysis of 145 responses. The findings of the study include the statistically significant effects of technological (relative advantage and compatibility), organizational (top management support and employees' readiness), and environmental (social influence and competitive pressure) factors on the adoption of MPS. Furthermore, this study also proved the positive and statistically significant effect of MPS on SMEs' performance. This study demonstrated that the TOE factor explains 70% variations in the adoption of MPS.

• The Journal of Economics, Marketing and Management
• /
• v.8 no.1
• /
• pp.36-49
• /
• 2020

Purpose - This study investigates factors that affected the utilization of trade support policies and further analyzed how the utilization of trade support policies affected export performance. Research design, data, and methodology - With a sample of 223 small and medium-sized export firms from South Korea, this study examines the determinants of the utilization level of trade support system such as export market orientation, learning orientation, network capability and environmental uncertainty by regression analysis. Results - Export market orientation have a positive effect on the utilization of the trade support system and there is positive relationship between learning orientation and the utilization of trade support system. And network capabilities have had a positive impact on the utilization of the trade support system but there is no relationship between environmental uncertainty and the utilization of trade support system. The utilization of the trade support system had a positive effect on export performance. Conclusions - The internal and external factors of the organization have affected small and medium-sized export firms use of trade support systems. The utilization of trade support system can enhance positive export performance by providing valuable information and resource to external knowledge and also to complementary resources from the external partners.

• East Asian mathematical journal
• /
• v.37 no.4
• /
• pp.443-460
• /
• 2021

This study analyzes the characteristics of elementary math gifted classes through the development and application of teaching and learning materials. We used the guided reinvention methods including quasi-experiential perspectives. To this end, the applicability of Lakatos' quasi-empirical mathematical philosophy in elementary mathematics was examined, and the criteria for the development of teaching and learning materials for gifted students were presented, and then this study was conducted in this theoretical background. The subjects of the study were 21 elementary students at P University's Institute of Science and Gifted Education, and non-face-to-face real-time classes were conducted. Classes were divided into introduction, deployment1, deployment2, organization stages, and in each stage, small group cooperative learning was conducted based on group activities, and in this process, the characteristics of elementary mathematics gifted were analyzed. As a result of the study, elementary mathematics gifted students did not clearly present the essence of justification in the addition algorithm of fractions, but presented various interpretations of 'wrong' mathematics. They also showed their ingenuity in the process of spontaneously developing 'wrong' mathematics. On the other hand, by taking interest in new mathematics starting from 'wrong' mathematics, negative perceptions about it could be improved positively. It is expected that the development of teaching and learning materials dealing with various and original topics for the gifted students in elementary school will proceed through follow-up research.

• Journal of Korean Society of Water and Wastewater
• /
• v.36 no.5
• /
• pp.275-287
• /
• 2022

In order to overcome the small scale of Korea waterworks and to achieve comprehensive improvement and innovation transformation, the waterworks integration was reviewed. The effect of consolidation was confirmed by the integration of the water supply business in the southern Gangwon region and the western Gyeongnam region in Korea, such as an increase in the flow rate and a decrease in the production unit cost. After facing management and service limitations overseas, more than 1,000 small-scale waterworks projects in the UK were integrated into 27 waterworks providers, and Japan also revised the Waterworks Act in December 2019 and is in the process of integrating waterworks. It is considered appropriate to promote the integration of waterworks projects in Korea by respecting the autonomy of local governments, but using a participatory method, a win-win method, and a linkage method. For the integration of waterworks projects, three strategies are proposed: First creating a national foundation for integration (revision of the Waterworks Act), Second establishing a waterworks integration strategy led by local governments, Third forming an external consensus and providing incentives for participation.

• The Journal of Asian Finance, Economics and Business
• /
• v.10 no.1
• /
• pp.101-109
• /
• 2023

This study examined the relationships among owner-manager characteristics, e-commerce adoption, and performance of small and medium enterprises (SMEs) in Malaysia. Although the growth of e-commerce was encouraging in many countries, studies of e-commerce adoption among SMEs in developing countries such as Malaysia are insufficient. Furthermore, studies that investigated individual characteristics and e-commerce adoption are still low in number. This study specifically employed the technology-organization-environmental (TOE) framework to develop its research model. The sample was selected by using a non-probability judgmental sampling technique because the desired population frame was unavailable. A total of 111 owner-managers of SMEs were surveyed using online self-administered questionnaires. Subsequently, the data was analyzed through partial least square-structural equation modeling (PLS-SEM). The results revealed significant relationships between owner-manager characteristics and e-commerce adoption, as well as between e-commerce adoption and the performance of SMEs. The findings suggested that owner-manager characteristics played an important role in determining e-commerce adoption among SMEs. Moreover, e-commerce adoption was crucial in affecting the performance of SMEs. This paper provided new insights into factors affecting e-commerce adoption and firm performance. It could further benefit the government and SMEs in strategizing e-commerce adoption and development, especially in the era of Industrial Revolution 4.0 (IR 4.0) and the post-COVID-19 pandemic.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
• /
• 2023.11a
• /
• pp.114-115
• /
• 2023

Research on eco-friendly ships is being actively conducted due to the strengthening of environmental regulations in the shipping sector by the International Maritime Organization (IMO). However, most studies are on large ships, and research on small ships is insufficient. Since most fishermen operate small boats, research on eco-friendly fuel vessels is necessary. This study performed resistance performance analysis, model tests, and POW tests to develop a hybrid electric propulsion ship, and compared and verified the CFD and model test results.