• Journal of Cancer Prevention
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• v.22 no.4
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• pp.203-210
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• 2017

After transcription, RNAs are always associated with RNA binding proteins (RBPs) to perform biological activities. RBPs can interact with target RNAs in sequence- and structure-dependent manner through their unique RNA binding domains. In development and progression of carcinogenesis, RBPs are aberrantly dysregulated in many human cancers with various mechanisms, such as genetic alteration, epigenetic change, noncoding RNA-mediated regulation, and post-translational modifications. Upon deregulation in cancers, RBPs influence every step in the development and progression of cancer, including sustained cell proliferation, evasion of apoptosis, avoiding immune surveillance, inducing angiogenesis, and activating metastasis. To develop therapeutic strategies targeting RBPs, RNA interference-based oligonucleotides or small molecule inhibitors have been screened based on reduced RBP-RNA interaction and changed level of target RNAs. Identification of binding RNAs with high-throughput techniques and integral analysis of multiple datasets will help us develop new therapeutic drugs or prognostic biomarkers for human cancers.

• Journal of the Korea Society of Computer and Information
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• v.23 no.11
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• pp.1-7
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• 2018

In this paper, we propose soft dead pixels detection method by analysing different response at hot and cold images. Abnormal pixels are able to effect detecting a small target. It also makes confusing real target or not cause of changing target size. Almost exist abnormal pixels after image signal processing even if dead pixels are removed by dead pixel compensation are called soft dead pixels. They are showed defect in final image. So removing or compensating dead pixels are very important for detecting object. The key idea of this proposed method, detecting dead pixels, is that most of soft deads have different response characteristics between hot image and cold image. General infrared cameras do NUC to remove FPN. Working 2-reference NUC must be needed getting data, hot & cold images. The way which is proposed dead pixel detection is that we compare response, NUC gain, at each pixel about two different temperature images and find out dead pixels if the pixels exceed threshold about average gain of around pixels.

• International Journal of Advanced Culture Technology
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• v.11 no.2
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• pp.381-388
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• 2023

Small-scale environmental impact assessments have limitations in terms of survey duration and evaluation resources, which can hinder the assessment and analysis of the current situation. In this study, we propose the use of drone technology during the environmental impact assessment process to supplement these limitations in the current situation analysis. Drone photography can provide rapid and accurate high-resolution images, allowing for the collection of various information about the target area. This information can include different types of data such as terrain, vegetation, landscape, and real-time 3D spatial information, which can be collected and processed using GIS software to understand and analyze the environmental conditions. In this study, we confirmed that terrain and vegetation analysis and prediction of the target area using drone photography and GIS analysis software is possible, providing useful information for environmental impact assessments.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.5
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• pp.754-763
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• 2018

The maritime ICT-convergence equipment are essentially required to a type approval (TA) certification that needs environmental and functional tests, to install in vessel. The environmental test is to experiment the possession for required durabilities of the target device in maritime environment, and the functional test is to check the required functions of target equipment based on international standard. In Korea, the environmental testing facilities amount to 227 sites, but there is no functional testing facility. Because of this, we establish a function test facility for the maritime ICT-equipment. In this paper, we analyze and design the functional testing requirement and required interlocking simulators for digital interfaces and navigation communication equipment. We propose the 2-steps of functional testing procedures, which are single test and integration test, to improve the reliability of testing result. The single test is to examine own functions of the target device, and the integration test is to check harmonized operation with other navigation and communication devices.

• Journal of Korean Society for Quality Management
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• v.23 no.1
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• pp.142-151
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• 1995

Since management innovation has been practiced only in the large entrepreneur, its application to small business seems to be very difficult. However, if the participation of all employees was properly provided, management innovation could be applied to every size of business with no difficulty or problem. Management innovation can be simply defined as an innovation in consciousness of entire employee to achieve a new target within the short period. Management innovation is not easy indeed, but may be obtained through the regimentation of each member's manpower in the small business. Through the goal setting and proper steps for the goal, management innovation can be obtained. Five S movement may be one of the basic step in the achievement of management innovation. Several factors that can affect the management innovation were reviewed and applied to small business in this study. The purpose of the study is in the settlement of business culture by the application of business innovation.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2003.11a
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• pp.219-222
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• 2003

This paper is to propose e-business strategies for individual SME's(small and medium-sized enterprises). e-business maturity model is used to assess e-business maturity level of a target SME, and then corresponding e-business strategy is proposed based on the current maturity level. We studied two SME's to show how it works. Most SME's are small and do not have enough resources to invest on information systems. As it turns out, e-business strategies of SME should heavily depend on its relationship with customers and suppliers. One of the studied SME's is found to be in higher maturity level, because its manufacturing system is tightly related to its customer. One of major implications of this study is that e-business level of SME's should be upgraded considering how it is doing business with its customers and suppliers.

• Proceedings of the Korea Society for Industrial Systems Conference
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• 1997.11a
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• pp.475-488
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• 1997

This study investigated the management environment of medium and small business by examining the role of medium and small business in national economics, the change in management condition, and the problems in quality and technique. Also we analyzed problems in the past quality control activity of our medium and small business, and examined the driving direction and intorduction method of QM. And to understand the effect of manager's concern in quality management to observe the quality system before and after introduction of QM. A target for this investigation is the medium and small business which has introduced QM through ISO 9000. Also analyzed how 05 observance effects to the sale price, process effect customer complaint and on-time delibery by an oral test.

• Korean Institute of Interior Design Journal
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• v.20 no.6
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• pp.19-26
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• 2011

The purpose of this study was to small house plans according to the preferred type of emotional design. The human emotions was a major factor for small houses plan's needs. In this study is direction of the basic plan for the small houses of the spatial planning and services and the needs of community facilities. Preferred types of emotional design was identify the propensity of consume, adjectives, colors and forms. For this study, survey methods were used for data collection. The effective numbers of survey questionnaire was 183, and the survey analysis has been made by using of SPSS win 18.0. The major findings were as followings: 1) Preferred types of emotional design were "Eco-Classic oriented group", "Unspecified commonness group", "Creative design oriented group" classified. 2) "Eco-Classic oriented group" wanted Eco-system and the community space. "Unspecified commonness group" wanted Simple and universal style. "Creative design oriented group" wanted flexible styles and various items. Therefore, depending on need group is the main target-specific as well as flat planning and interior style facilities and the provision of services to be competitive in the small house could indicate. These results can provide improvement guidelines for the small house plans.

• KIEAE Journal
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• v.7 no.5
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• pp.53-58
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• 2007

In order to predict the indoor air pollutant, the VOCs emission rate is used through small chamber in the design process. However, the small chamber method has limitations as the convective mass transfer coefficient, the most important factor when predicting VOCs contamination of indoor air, is different between the small chamber result and the measured data in the actual building. Furthermore, the existing studies which analyzed mass transfer coefficient in the small chamber were directed on the small chambers developed at the time and FLEC(Field and Laboratory Emission Cell), thus, are different from the current small chamber which has been changed with improvements. The purpose of this study is to determine the emission rate of pollutant in multi-layered building materials, and predict the indoor pollutant concentration through the CFD(Computational of Fluid Dynamics) and CRIAQ2 based on the mass transfer coefficient on singled-layered building material by using the current small chamber widely used in Korea. Futhermore, this study used the new convective mass transfer coefficient(hm') which indicates the existing convective mass transfer coefficient(hm) including VOC partition coefficient(k). Also, formaldehyde was selected as target pollutant.

• Korean Journal of Occupational Health Nursing
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• v.15 no.2
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• pp.153-164
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• 2006

Purpose: This study aimed to develop hypertension control programs and to analyse their effects in small scale enterprises(SSE). Method: One program was based on 'Transtheoretical Model and Stages of Change' and named 'Individual Approach'. Another program was based on 'Ecological Model' added to the former theory and named 'Integrating Approach'. The target population of the programs are 33 and 34 workers each. The two intervention programs were conducted for 18 weeks after a pre-intervention survey. Immediately after the programs end, first post-intervention survey was done, and second post-intervention survey was done after 28 weeks. Results: First, at the beginning of intervention, the target workers were evenly distributed over the five stages of Transtheoretical Model. But after the intervention, all workers were found in the maintenance stage. Second, the blood pressure level was diminished in the two programs. In Individual Approach, the workers have lost systolic blood pressure by 17.3 mmHg and diastolic blood pressure by 11.8mmHg. In Integrating Approach, the workers have lost systolic blood pressure by 20.0mmHg and diastolic blood pressure by 15.0mmHg. Conclusion: Integration Approach is more favorable than Individual Approach as an intervention program of hypertension in small scale enterprises.