• Journal of Sasang Constitutional Medicine
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• v.16 no.1
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• pp.44-52
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• 2004

1. Objects of Research This research is purposed to find Dong-mu's thought on Pharmacology, through summarizing sentences related to pharmacology proposed in the chief writings on Sasang Constitutional Medicine. 2. Methods of Research It was researched bibliologically with Dong-mu's chief medical writings such as "Dongyi Suse Bowon Sasang Chobongyun(東醫壽世保元四象草本卷)", "Dong-mu's posthumos work(東武遺藁)", "Dongyi Suse Bowon(東醫壽世保元)". 3. Results and Conclusions 1. The grouping criteria according to the constitution proposed in "Dongyi Suse Bowon Sasang Chobongyun" is 'Spreading Outside' 'Hardening Inside' 'Cooling Organ' 'Warming Inside', but the grouping of medical herbs according to the constitution is yet not accomplished, and medical herbs is comprehended on base of effectiveness as like existing oriental medicine. 2. The grouping criteria according to the constitution proposed in "Dong-mu's posthumos work"is 'Spreading Choking Raising Lowering' and 'Perfume Smell Fluid Taste', and medical herbs is comprehended on base of effectiveness as like "Chobongyun", and the example on mixing of the herb classified according to the constitution is showed. 3. The medical herbs are comprehended on the basis of how to effect on treatment of constitutional disease, and the principle that it's not to mix of the herb classified according to the constitution is proposed in "Dongyi Suse Bowon". 4. The pharmacology of Sasang Constitutional Medicine is accomplished after it is modified many ti mes through clinic experience for a long time. 5. The pharmacology of Sasang Constitutional Medicine in the early period, is to comprehend herbs on the basis of how to complement 'Spreading Gathering Raising Lowering' of 'Small-Organ(偏小之臟)' according 'Qi-Mei(氣味)' and effectiveness, but that in the late period is to comprehend herbs on the basis of how to complement or to control 'Small-Organ(偏小之臟)' and 'Large Organ(偏大之臟)'.

• Journal of Korean Neurosurgical Society
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• v.59 no.6
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• pp.551-558
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• 2016

Malignant glioma cells invading surrounding normal brain are inoperable and resistant to radio- and chemotherapy, and eventually lead to tumor regrowth. Identification of genes related to motility is important for understanding the molecular biological behavior of invasive gliomas. According to our previous studies, Metallothionein 1E (MT1E) was identified to enhance migration of human malignant glioma cells. The purpose of this study was to confirm that MT1E could modulate glioma invasion in vivo. Firstly we established 2 cell lines; MTS23, overexpressed by MT1E complementary DNA construct and pV12 as control. The expression of matrix metalloproteinases (MMP)-2, -9 and a disintegrin and metalloproteinase 17 were increased in MTS23 compared with pV12. Furthermore it was confirmed that MT1E could modulate MMPs secretion and translocation of NFkB p50 and B-cell lymphoma-3 through small interfering ribonucleic acid knocked U87MG cells. Then MTS23 and pV12 were injected into intracranial region of 5 week old male nude mouse. After 4 weeks, for brain tissues of these two groups, histological analysis, and immunohistochemical stain of MMP-2, 9 and Nestin were performed. As results, the group injected with MTS23 showed irregular margin and tumor cells infiltrating the surrounding normal brain, while that of pV12 (control) had round and clear margin. And regrowth of tumor cells in MTS23 group was observed in another site apart from tumor cell inoculation. MT1E could enhance tumor proliferation and invasion of malignant glioma through regulation of activation and expression of MMPs.

• Journal of The Korea Institute of Healthcare Architecture
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• v.12 no.2
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• pp.31-39
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• 2006

Much has changed in the healthcare field since the beginning of the industrial age. In the healthcare field changes are occurring so rapidly and dramatically that yesterday's paradigm will not be tomorrow's paradigm, creating the need above all else to stay fluid and flexible as strategies(included healthcare architecture planning) for the future are developed. The purpose of this study is to analyze the latest architectural trends of general hospital outpatient department based on the healthcare environment changes in Korea. The major healthcare environment change is to change the object of hospital's healthcare services from inpatient to outpatient. In conclusion, the first, medical faculties of outpatient department are subdivided specialized small faculty. The second, clinic systems for medical examination and treatment of specific disease are activated in the most outpatient department. The third, specialized medical centers for chronical disease(Cancer, Cardiac etc.) control are arranged in existed outpatient department or freestanding facility. Specialized medical center for preventive medicine is regionally decentralized for corresponding with the healthcare paradigm shifts.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.8 no.1
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• pp.36-49
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• 1998

The purpose of this study is to investigate the relationship between the work postures and upper extremity cumulative trauma disorders(CTDs) in female medical insurance bill reviewers(n=448). This study included diagnosis for CTDs, anthropometry and job analysis (workstations and posture). The characteristics of subject were 33.6 years of average age and 8.7 years of average work duration. The results were as fallows. Ergonomic conditions of workstation were unsuitable compared with anthropometry result. The height of work surface(79.5 cm) and chair(43.0 cm)were high. work space was small, and legs space under the table was limited. Work postures were awkward compared with recommended neutral postures. Neck flexion($21.0-36.0^{\circ}$), elbow elevation, shoulder abduction ($46.0-47.0^{\circ}$). wrist radial and ulnar deviation, forearm supination and pronation, and wrist repeated motion(12.7-21.5 freq./min) were analyzed as hazardous risk factors by job analysis. The prevalence of CTDs was 32.8 % by medical diagnosis. The prevalence rate of CTDs in hazardous work posture group was significantly greater than safe work posture group both neck-shoulder (relative prevalence = 5.2, p<0.001) and wrist-hand (relative prevalence = 2.5, p<0.05).

• Journal of Computing Science and Engineering
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• v.6 no.1
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• pp.67-78
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• 2012

People are willing to spend more for their health. Traditional medical services are hospital-centric and patients obtain their treatments mainly at the clinics or hospitals. As people age, more medical services are needed to exceed the potentials of this hospital-centric service model. In this paper, we present the design and implementation of CardioSentinal, a 24-hour heart care and monitoring system. CardioSentinal is designed for in-home and daily medical services. It mainly focuses on the outpatients and elderly. CardioSentinal is an interdisciplinary system that integrates recent advances in many fields such as bio-sensors, small-range wireless communications, pervasive computing, cellular networks and modern data centers. We conducted numerous clinic trials for CardioSentinal. Experimental results show that the sensitivity and accuracy are quite high. It is not as good as the professional measurements in hospital due to harsh environments but the system provides valuable information for heart diseases with low-cost and extreme convenience. Some early experiences and lessons in the work will also be reported.

• Journal of Oriental Neuropsychiatry
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• v.34 no.4
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• pp.463-471
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• 2023

Objectives: Medical personnel are professionals subject to stressful situations and psychological distress. This case series reports the results of a mindfulness meditation program combined with digital health for medical personnel at a Korean medicine (KM) hospital. Methods: An online mindfulness program was implemented in 2022 to improve the mental health of nursing staff in a KM clinic. The online mindfulness program, which was supplemented based on previous results and limitations, was applied to KM doctors and nurses working at a KM hospital in this case series. An important difference from the existing case series was the introduction of a smartphone application that promoted the daily routine of meditation. A total of 7 medical personnel, including 4 doctors and 3 nurses, participated in the program. Results: After participating in the program, an increase in deep acting and a decrease in surface acting, which are aspects of emotional labor, were consistent with the results of a previous case series. However, the patterns of change in burnout and hwa-byung symptoms differed depending on the occupation of the participants. Participants' satisfaction with this program and the smartphone application and willingness to recommend it to colleagues were high. Conclusions: As this study was only a small case series, the author plans to continue to expand and improve the program based on the findings.

• The Journal of Korean Medical History
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• v.26 no.2
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• pp.111-122
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• 2013

Korean medical journals were continuously published during the period of Japanese colonization of Korea. Various advertisements by herbal drugs manufacturers were in these journals, targeting Korean medical doctors or students who aspired to be Korean medical doctors. The advertisements varied from small ones to large-scale ads. At first these advertisements covered only dried herbs, but with time, they came to advertise various kinds of drugs. Advertisement of merchandise drugs brought many changes to the medical culture of Korea. Korean medical doctors who only prescribed dried herbs before began to prescribe merchandise drugs as well. When treating patients, they not only used Korean drugs but also actively prescribed merchandise drugs and western drugs, showing an advancement in treatment. As Korean medical doctors played the role of providers of merchandise drugs, herbal drugs manufacturers and Korean medical doctors seemed as sellers and consumers on the surface. However, they maintained a relationship where Korean medicine worked as the common denominator. Among merchandise drugs, Yoeng-so-hwan, Bi-jeon-go, and Myeol-dok-hwan were advertised often, and this shows that people at the time suffered mostly from digestive diseases, skin diseases, and sexually transmitted diseases. Herbal drugs manufacturers were business managers whose main objective was to make a good profit, but they consisted a part of Korean medical society. Like Korean medical doctors, they were anxious about the fall of Korean medicine. As a part of popularization of Korean medicine, they encouraged Korean medical doctors to treat patients using herbal drugs and merchandise drugs. This thought was reflected well in advertisements and Korean medical doctors made use of this thought well.

• Women's Health Nursing
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• v.8 no.3
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• pp.389-401
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• 2002

This study aims to find factors that affect variations in cesarean section frequency rates among OBGY clinics in Metropolitan areas. The factors include patient, medical supplier characteristics and economic factors. This study is a cross-sectional analysis using health insurance delivery claims from July to December 2000 and files of the NHIC(national health insurance corporation). Multiple regression was used to analyze the dependent variable of cesarean section frequency rate at each clinic. The results are as follows : Cesarean section frequency rate is increasing in proportion to the number of the following patients : repeated caesarean section, disproportion, obstructed labour, fetal distress, emergency caesarean section and self-employed patients. There are geographic variations as well. Cesarean section frequency rates are higher in Inchon and Gyonggi province than in Seoul. The higher number of total delivery the clinic has, the lower rate of cesarean section it has. Clinics with high frequency rates in 1999 showed higher rates the next year. Further research is required to develop evidence based delivery modes and change strategies for increasing normal delivery and activating midwife clinics.

• Progress in Medical Physics
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• v.20 no.4
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• pp.260-268
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• 2009

In this study, we estimated inhomogeneity correction factor in small field. And, we evaluated accuracy of treatment planning and measurement data which applied inhomogeneity correction factor or not. We developed the Inhomogeneity Correction Phantom (ICP) for insertion of inhomogeneity materials. The inhomogeneity materials were 12 types in each different electron density. This phantom is able to adapt the EBT film and 0.125 cc ion chamber for measurement of dose distribution and point dose. We evaluated comparison of planning and measurement data using ICP. When we applied to inhomogeneity correction factor or not, the average difference was 1.63% and 10.05% in each plan and film measurement data. And, the average difference of dose distribution was 10.09% in each measurement film. And the average difference of point dose was 0.43% and 2.09% in each plan and measurement data. In conclusion, if we did not apply the inhomogeneity correction factor in small field, it shows more great difference in measurement data. The planning system using this study shows good result for correction of inhomogeneity materials. In radiosurgery using small field, we should be correct the inhomogeneity correction factor, more exactly.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.1
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• pp.93-104
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• 2019

This study examined the relationship between the number of medical technologists and the medical test count. Data was obtained from 441 medical technologists in a hospital through a self-reported questionnaire. The Pearson correlation test, student's t-test, ANOVA or descriptive statistics were performed for data analysis. The distribution of medical technologist according to the size of hospitals was small 5.8, medium 14.9, large 25.8, and super 45.4. The analysis demonstrated a relationship between the number of medical technologists and the number of medical tests in the field, number of clinical tests per MT, and number of optimal medical test per MT according to the hospital size (P<0.001). The average time for quality control by the department at a higher hospital was less than two hours. In terms of the satisfaction of salary, work environment, test accomplishment, and welfare service, the dissatisfaction of medical technologists in small and medium hospitals was higher than those in large and super hospitals. Overall, a focus on intensifying systemic supplementation and improving the condition of medical technologists is needed to provide reliable data for medical examinations in medical areas.