• Journal of Preventive Medicine and Public Health
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• 제55권2호
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• pp.173-181
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• 2022

Objectives: Anxiety disorder is among the most prevalent mental illnesses among adolescents. Early detection and proper treatment are important for preventing sequelae such as suicide and substance use disorder. Studies have suggested that sleep duration is associated with anxiety disorder in adolescents. In the present study, we investigated the association between sleep quality and anxiety in a nationally representative sample of Korean adolescents. Methods: This cross-sectional study was conducted using data from the 2020 Korea Youth Risk Behavior Web-based Survey. The Generalized Anxiety Disorder-7 questionnaire was used to evaluate anxiety. The chi-square test was used to investigate and compare the general characteristics of the study population, and multiple logistic regression analysis was used to analyze the relationship between sleep quality and anxiety. Results: In both sexes, anxiety was highly prevalent in participants with poor sleep quality (adjusted odds ratio [aOR], 1.56; 95% confidence interval [CI], 1.43 to 1.71 in boys; aOR, 1.30; 95% CI, 1.19 to 1.42 in girls). Regardless of sleep duration, participants with poor sleep quality showed a high aOR for anxiety. Conclusions: This study identified a consistent relationship between sleep quality and anxiety in Korean adolescents regardless of sleep duration.

• Journal of Preventive Medicine and Public Health
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• 제56권5호
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• pp.458-466
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• 2023

Objectives: The association between long sleep duration and mortality is frequently attributed to the confounding influence of comorbidities. Nevertheless, past efforts to account for comorbidities have yielded inconsistent outcomes. The objective of this study was to evaluate this relationship using a large prospective cohort in Korea. Methods: The study included 114 205 participants from the Health Examinees Study, who were followed for a median of 9.1 years. A composite comorbidity score was developed to summarize the effects of 21 diseases. Using Cox proportional hazards regression, hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause, cancer, and cardiovascular mortality associated with sleep duration were estimated. These estimates were adjusted for socio-demographic factors, lifestyle factors, body mass index, and comorbidity score. Additionally, a stratified analysis by subgroups with and without comorbidities was conducted. Results: Throughout the follow-up period, 2675 deaths were recorded. After all adjustments, an association was observed between a sleep duration of 8 hours or more and all-cause mortality (HR, 1.10; 95% CI, 1.01 to 1.20). However, no such association was detected in the stratified analysis for the subgroups based on comorbidity status. Conclusions: Long sleep duration was found to be associated with all-cause mortality among Koreans, even after adjusting for comorbidities. Additional studies are required to explore the mechanism underlying the association between sleep duration and major causes of mortality.

• 동의생리병리학회지
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• 제36권1호
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• pp.7-10
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• 2022

Hwangryunagyo-tang (HT) is a herbal cocktail to treat insomnia induced by yin deficiency with effulgent fire. In the present study, the onset time and the duration time of sleep were measured 30 minutes after thiopental sodium injection. And c-fos immunohistochemistry was performed to find the activated nerve cells of the ventrolateral preoptic nucleus (VLPO) and tuberomammillary nucleus (TMN) sites in the brain. HT significantly increased the number of activated nerve cells in the sleep-inducing center (VLPO), whereas HT significantly decreased the number of activated nerve cells in the arousal center (TMN). It could be concluded that the HT shortened the onset time and increased the duration time for sleep induced by thiopental sodium. And it was confirmed that the mechanism acted by activating the sleep-inducing center (VLPO) and suppressing the arousal center (TMN) in the brain. The results are considered to be useful as scientific evidence HT can be used clinically for the treatment of insomnia caused by yin deficiency with effulgent fire.

• Human Ecology Research
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• 제57권2호
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• pp.281-293
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• 2019

This study aimed to examine the effects of socially prescribed perfectionism, sleep duration, and sleep quality on suicidal ideation in Korean high school students and to investigate if sleep duration and quality moderated the relationship between socially prescribed perfectionism and suicidal ideation. The participants of this study were 840 students (544 boys and 296 girls) from six high schools located in Seoul and Gyeonggi-do. The Suicidal Ideation Questionnaire (Reynolds, 1988) was used to measure suicidal ideation. And the socially prescribed perfectionism was assessed by the Multidimensional Perfectionism Scale (Hewitt & Flett, 1991). The students were asked to respond to a question regarding how long they slept a day as well as the Sleep Quality Scale (Yi, 2005). The data were analyzed with descriptive statistics and hierarchical regressions. The moderating effect of sleep duration and quality were investigated using the analysis procedures proposed by Baron and Kenny (1986). The results showed that the level of socially prescribed perfectionism and sleep quality increased the level of suicidal ideation. In addition, sleep quality moderated the relationship between socially prescribed perfectionism and suicidal ideation. The effect of socially prescribed perfectionism on suicidal ideation was greater when sleep quality was poor, compared to when it was good.

• Journal of Korean Biological Nursing Science
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• 제20권2호
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• pp.103-113
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• 2018

Purpose: This study was performed to assess problems associated with sleep (short and long sleep duration) and to identify risky subgroups with sleep problems among adult cancer survivors. The study is based on the Korea National Health and Nutrition Examination Survey (KNHANES VI and VII) from 2013 to 2016. Methods: The sociodemographic and clinical data of 504 Korean cancer survivors aged 20-64 years was extracted from the KNHANES VI and VII database. Descriptive statistics for complex samples was used, and decision-tree analyses were performed using the SPSS WIN 24.0 program. Results: The mean age for survivors was approximately 51 years. The mean sleep duration was 6.97 hours; 36.2% of participants had short (< 7 hours) and 9.9% had long (> 8 hours) sleep duration. From the decision-trees analyses, the characteristics of the adult cancer survivors related to sleep problems were presented with six different pathways. Sleep problems were analyzed according to the survivors' sociodemographic information (age, education, living status, and occupation), clinical characteristics (body mass index, hypercholesterolemia, and anemia) and health-related quality of life (HRQoL). The HRQoL (${\leq}0.5$ or > 0.5 cutoff point) was a significant predictor of the participants' sleep problems because all six pathways were started from this predictor in the model. Conclusion: Health care professionals could use the decision-tree model for screening adult cancer survivors with sleep problems in clinical or community settings. Nursing interventions considering these specific individual characteristics and HRQoL level should be developed to have adequate sleep duration for Korean adult cancer survivors.

• 수면정신생리
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• 제6권2호
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• pp.116-125
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• 1999

Objectives: The purpose of this study is to investigate the effect of exercise load on sleep structure and stress hormone secretion during sleep. Methods: Five male physical education students were included in this study after giving their written, informed consents in the Research Institute for Sports Science at the University of Hanyang. All subjects have performed for at least 3 years in a regular aerobic exercises such as football, basketball, and running. The subjects were divided into three groups ; NOE(non-exercise), MDE(middle duration exercise), LDE(long duration excercise). MDE group maintained a total of 120 min exercise, and LDE group maintained a total of 300 min exercise by football, basketball or badminton. All subjects were acclimatized to the experimental sleep condition by spending one night under expermental conditions, including the placement of an intravenous catheter. During the subsequent night(24:00-08:00), somnopolygraphic sleep recordings were obtained, and blood for measuring growth hormone, cortisol, testosterone, and $\beta$-endorphin was collected every 120 min throughout the night. Blood samples were obtained from prominent forearm veins of subjects. Then, the samples were immediately placed in ice and centrifuged within 10 min at 3000 rpm at $4^{\circ}C$. Statistical analyses were performed using the SPSS/$PC^+$. Data were analyzed by one-way ANOVA with repeated measures. Results: No significant differences among groups were observed in sleep latency, total sleep time, stage 2 sleep, and slow wave sleep. However, daytime exercise produced significant changes in stage 1 sleep, REM sleep, stage 2 sleep latency, REM sleep latency and sleep efficiency. Stage 1 sleep, stage 2 sleep latency, and REM sleep latency significantly increased in LDE compared to those of NOE and MDE groups. But the amount of REM sleep significantly decreased in LDE. Sleep efficiency of MDE was higher than those of NOE and LDE. The blood concentrations of growth hormone, testosterone, and cortisol during night sleep were significantly lower in LDE than in NOE. $\beta$-endorphin concentrations in blood during night sleep were not different among groups. Conclusion: The daytime exercise load was significantly related to sleep structure and stress hormone secretion during night sleep. Long duration exercise showed a harmful effect on sleep structure and hormone secretion. However, middle duration exercise had a beneficial effect on sleep structure and hormone secretion during sleep.

• 수면정신생리
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• 제24권2호
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• pp.86-96
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• 2017

목 적 : 본 연구는 폐쇄성 수면무호흡증 환자에서 수면무호흡지수, 수면관련척도, 기분관련척도, 그리고 인지기능간의 연관성을 보고자 하였다. 방 법 : 폐쇄성 수면무호흡증후군을 보이는 105명의 환자를 선정하였다. 수면무호흡지수로 RDI, AHI가 사용되었고, 수면관련척도로는 PSG에서 측정되는 TST, Duration N1, Duration N2, Duration N3, Duration R, Arousal Index, PLM Index, Snoring Index, Mean SpO2, Minimum SpO2와 설문지로 측정되는 PSQI, ESS, SIS (snoring index by scale)를 사용하였으며 기분관련척도로는 BDI, 인지기능관련 척도로는 Moca-K, MMSE-K, CDR을 사용하였다. 이를 이용하여 수면무호흡증 환자에서 수면무호흡지수, 수면 및 기분관련척도와 인지기능간의 상관관계를 분석하였으며 수면무호흡증 환자에서 보이는 인지기능장애의 기전을 밝히고자 우울증의 매개효과를 분석하였다. 결 과 : Duration N1가 증가할수록 그리고 TST가 감소할수록 MOCA-K에 부적 인과관계를 나타내었다(p < 0.01). BDI와 Supine RDI가 증가할수록 MOCA-K에 부적 인과관계를 보였다(p < 0.01). PSQI가 증가할수록(p < 0.001) 그리고 MMSE-K가 감소할수록(p < 0.01) 또한 SIS가 증가할수록(p < 0.01) BDI에 정적 인과관계를 보였다. 폐쇄성수면무호흡증 환자에서 나이가 MOCA-K에 미치는 영향에 BDI가 부분 매개하는 것으로 확인되었다. 결 론 : 수면무호흡증 환자에서 Duration N1, TST, BDI, Supine RDI가 인지기능과 연관성이 있었으며, 특히 BDI로 측정되는 우울증상이 수면무호흡증 환자의 인지기능저하에 부분적으로 매개 하였다.

• 융합정보논문지
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• 제12권4호
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• pp.219-230
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• 2022

본 연구는 국민건강영양조사 2019년 제8기 자료를 활용하여 한국인의 성인 남녀의 비만과 수면시간과의 연관성을 규명하기 위해 시도하였다. 연구 대상자는 5,213명이었고, SPSS Win 27.0 프로그램을 이용하여 빈도분석, 기술통계, 다변량 회귀분석을 실시하였다. 참여자의 1일 평균 수면시간은 6.8시간이었고 평균 체질량지수(BMI)는 23.9kg/m2이었다. 수면 시간에 영향을 미치는 요인을 이변량 분석한 결과 연령, 교육수준, 스트레스, 우울증, 당뇨, 고혈압, 관절염이 종속변수인 수면시간과 통계적으로 유의한 관련성이 있었다. 수면시간이 6시간 미만인 군의 체질량지수(BMI)는 24.4로서 다른 군에 비해 높았으며 수면시간과 BMI는 통계적으로 유의한 음의 상관관계가 있었다(B=-0.247; 95% CI=-0.334~-0.160). 결과적으로 성인의 비만을 예방하기 위해서는, 수면시간을 증가시키기 위한 국가와 지역사회의 다양한 노력이 필요하다.

• Clinical and Experimental Pediatrics
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• 제64권3호
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• pp.111-116
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• 2021

In infants and young children, bedtime problems and night waking are common and the main presentations of insomnia. Poor sleep may critically impact the daytime functioning and mood of the child and their caregivers. A comprehensive sleep history, a sleep diary/log, and the BEARS (Bedtime problems, Excessive daytime sleepiness, Awakenings during the night, Regularity and duration of sleep, and Sleep-disordered breathing) sleep screen are useful for diagnosing sleep problems in young children. Behavioral therapies for this type of insomnia include extinction, bedtime fading with positive routines, and scheduled awakening. Previous studies of behavioral interventions for young children showed significant improvements in sleep-onset latency, night waking frequency, and night waking duration. Parent education about their child's sleep, bedtime routines, and sleep hygiene is essential for treatment.

• 한국가정과교육학회지
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• 제30권4호
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• pp.1-14
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• 2018

본 연구는 우리나라 중·고등학생의 수면시간의 특성과 정신건강 문제, 영양섭취 상태의 관련성을 조사하였다. 이를 위해 2007~2016년 국민건강영양조사 원시자료를 바탕으로 총 5,489명(중학생 2,795명, 고등학생 2,694명)을 대상으로 분석하였다. 수면시간과 정신건강과의 연관성은 로지스틱 회기분석을 사용하여 분석하였고, 수면시간과 영양 섭취량의 연관성은 일반선형모델로 분석하였다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 수면시간을 분석한 결과, 중학생이 고등학생보다 평균 수면시간이 더 많았다(P<0.0001). 둘째, 수면시간과 정신건강 문제의 관련성은 중학생의 경우 수면시간이 증가할수록 스트레스 인지율(P<0.0001)과 자살생각 여부(P=0.0005)는 유의적으로 더 낮게 나타났다. 고등학생은 수면시간이 6-7시간인 그룹이 6시간 미만인 그룹에 비해 자살생각이 53% 더 적었고, 7-8시간인 그룹이 6시간 미만인 그룹에 비해 자살생각이 37% 더 적었다. 수면시간에 따른 스트레스 인지 여부의 연관성은 중학생과 고등학생 간에 통계적으로 유의한 차이가 있었다(P for interaction=0.02). 셋째, 수면시간에 따른 주요 영양소 1일 섭취량은 고등학생의 경우 수면시간이 9시간 이상인 그룹에서 비타민C의 섭취량이 높은 것으로 나타났다(P=0.003). 넷째, 수면시간에 따른 영양소 섭취상태는 고등학생의 경우 수면시간이 길수록, 인, 리보플라빈, 나이아신, 비타민C가 영양소 적정비와 평균영양소 적정비가 증가하였다. 청소년의 수면시간과 스트레스 인지와 자살생각 그리고 영양소 섭취상태는 연관성이 있음을 알 수 있었으며 이러한 결과는 청소년기 수면이 가지는 정신적 중요성을 강조하고, 영양교육의 기초자료로 이용될 수 있을 것이다.