• Title/Summary/Keyword: Skin reference

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Entrance Skin Dose According to Age and Body Size for Pediatric Chest Radiography (소아 흉부촬영 시 나이와 체격에 따른 입사피부선량)

  • Shin, Gwi-Soon;Min, Ki-Yeul;Kim, Doo-Han;Lee, Kwang-Jae;Park, Ji-Hwan;Lee, Gui-Won
    • Journal of radiological science and technology
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    • v.33 no.4
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    • pp.327-334
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    • 2010
  • Exposure during childhood results in higher risk for certain detrimental cancers than exposure during adulthood. We measured entrance skin dose (ESD) under 7-year children undergoing chest imaging and compared the relationship between ESD and age, height, weight, chest thickness. Though it is important to measure chest thickness for setting up the exposure condition of chest examination, it is difficult to measure chest thickness of children. We set up exposure parameters according to age because chest thickness of children has correlation with age. In the exposure parameters, for chest A-P examination under 2 year-children, tube voltage (kVp) in hospital A was higher than that in hospital B while tube current (mAs) was higher in hospital B, thus the ESD values were about 1.7 times higher in hospital B. However, for chest P-A examination over 4 year-children, the tube voltage was 7 kVp higher in hospital B, the tube current were same in all two systems, and focus to image receptor distance (FID) in hospital B (180 cm) was longer than that in hospital A (130 cm), thus the ESD values were 1.4 times higher in hospital A. For same ages, the ESD values for chest A-P examinations were higher than those for chest P-A examinations. Comparing ESD according to age, ESD values were $154{\mu}Gy$, $194{\mu}Gy$ and $138{\mu}Gy$ for children under 1 year, 1 to under 4 years and 4 to under 7 years of age, respectively. These values were lower than reference level ($200{\mu}Gy$) recommended in JART (japan association of radiological technologists), however these were higher than reference values recommended by EC (european commission), NRPB (national radiological protection board) and NIFDS (national institute of food & drug safety evaluation). In conclusion, the values of ESD were affected by exposure parameters from radiographer's past experience more than x-ray system. ESD values for older children were not always higher than those for younger children. Therefore we need to establish our own DRLs (diagnostic reference levels) according to age of the children in order to optimize pediatric patient protection.

A study on the development of hydrocortisone certified reference material in cosmetic cream using isotope dilution-mass spectrometry (동위원소희석-질량분석법을 이용한 화장품 크림 중 히드로코르티손 인증표준물질 개발 연구)

  • Chae-Hong Lee;Ji-Sun Huh;Eun-Ji Jeong;Hyun-Ah Kim;Min-Young Eom
    • Analytical Science and Technology
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    • v.37 no.3
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    • pp.166-173
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    • 2024
  • Steroids have a temporary skin improvement and whitening effect by controlling vasodilation, but they also cause side effects when used for a long time. Therefore, steroids were designated and managed as raw materials that cannot be used in cosmetics in Korea. However, steroids are continuously being detected in cosmetics, causing social issues. In this study, we developed a certified reference material (CRM) for the determination of steroids such as hydrocortisone in cosmetics. A cream-type cosmetic CRM was manufactured and subsequently certified following the guidelines outlined in ISO Guide 35. Homogeneity, short-term stability, and long-term stability were evaluated using isotope dilution mass spectrometry (ID-MS). The certified values were determined by using NIST's primary reference material to ensure traceability. From now on, we intend to supply the certified reference material as a cosmetic CRM to national and international companies, as well as research institutes after certification as certified reference material from KOLAS and registering on COMAR.

Comparison of Performance between Regular Drilled Shaft and Isolation Tube Drilled Shafts (일반 현장 타설 말뚝과 분리형 현장 타설 말뚝의 거동 비교)

  • Kim, Myung-Hak;O'Neill, Michael W.
    • Journal of the Korean Geotechnical Society
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    • v.16 no.1
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    • pp.211-220
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    • 2000
  • An experimental study that included detailed observation of four 305-mm-diameter drilled shafts, one reference shaft of standard design and three test shafts with isolation tubes to mitigate skin friction in the vadose zone of a clay soil profile, is described. The shafts were loaded only by naturally expanding and contraction soil over a period of 17 months. The soil at the test site was instrumented to track suction and elevation changes. Maximum ground surface movements exceeding 40 mm were observed. Heave movements of less than 1.5 mm were observed in the test shafts with isolation tubes, while movements of 5 mm were observed in the reference shaft. Unit side shear loads in the shafts protected by the isolation tubes were minimal compared to those measured in the reference shaft. This indicates that the isolation tubes were very effective.

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A Study On Effects of The Termination Conditions on Crosstalk in The A/D Converter Circuit (A/D 변환기 회로에서 터미네이션 임피던스의 crosstalk에 대한 영향 분석)

  • Lim, Han-Sang
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.47 no.2
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    • pp.35-42
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    • 2010
  • In this study, crosstalk between dominant interconnect pairs in an A/D converter circuit is analyzed in frequency domain and effects of termination conditions on crosstalk are described, based on the practical circuit conditions. An A/D converter circuit is a mixed circuit where both clean and noisy signals coexist such that the circuit probably suffers from distortion by crosstalk. An analog input signal and the reference voltage signal, which dominate the overall conversion performance of the A/D converter circuit, are ready to be distorted by crosstalk and include specific termination conditions, such as non-matching and capacitive termination, respectively. Thus, this study presents the model of crosstalk considering impedance mismatch at both ends and analyzes effects of the practical termination conditions in the analog input and the reference voltage interconnects on crosstalk. A typical circuit configuration of the two interconnects is described and crosstalk including near-end and far-end termination impedances is modeled. Effects of the near-end impedance mismatch in the analog input interconnect and the far-end capacitive termination in the reference voltage interconnect are estimated in the frequency domain by using the model of crosstalk and experiments are performed to confirm the estimated results. Microstrip lines are used as interconnects, involving the increase of loss in high frequencies.

Establishment of reference intake of water for Korean adults in 2015 (2015 한국 성인의 수분 섭취기준 설정)

  • Lee, Jae-Hyun;Kim, Sun-Hyo
    • Journal of Nutrition and Health
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    • v.50 no.2
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    • pp.121-132
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    • 2017
  • Purpose: This review was performed to establish a reference intake of water for Korean (KDRI-water) adults in 2015 by examining current knowledge of the relationship between water intake and health and the general status of water intake and loss. We expect that this study will be utilized for further refinement of KDRI-water. Methods: Documents were searched using RISS, NDSL, DBPIA, CINAHL, and Pubmed with the keywords 'water intake, water supply, water ingestion, hydration, dehydration, water balance, and fluid balance'. Results: Water balance is essential for the maintenance of health. Based on this assumption, numerous studies have been performed to investigate the association of water intake with several diseases such as urolithasis, obesity, diabetes, and cancer as well as other health problems, including constipation, cognition, and fetal weight. Effects of water intake for prevention or relief of these health problems vary. Water is supplied to the body by eating foods and drinking liquids such as plain water and beverages. Metabolic water is another source of water input. Water is lost through urine, skin, respiration, and feces. KDRI-water 2015 was set by adequate intake (AI) based on water intake volume, which was the sum of water intakes from foods and fluids reported by the Korea National Health and Nutrition Examination Survey, with extra milk intake of 200 mL. AIs in some age groups were modified considering their estimated energy requirements. Conclusion: Accurate data of water intake is critically important for the establishment of KDRI-water. Therefore, improvement of systems investigating water intake is required, and more studies on the status of water intake and loss in Korean people are needed for definite KDRI-water establishment.

Speckle Reduction Method in Wavelet Domain for OCT Image Enhancement (OCT 영상 개선을 위한 웨이블릿 영역에서의 Speckle 저감 방법)

  • Lee Chang-Su;Na Ji-Hoon;Lee Byeong-Ha;Chang Ju-Wan
    • Journal of Institute of Control, Robotics and Systems
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    • v.12 no.4
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    • pp.364-370
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    • 2006
  • Optical coherence tomography (OCT) is high resolution medical imaging system which is obtaining image inside biological objects with non-destructive method. OCT system is based on Michelson interferometer with a reciprocating mirror in the reference arm and a biological object in the sample arm. The obtained OCT image suffers from a granular or mottled image, called speckle. Speckle is caused by random interferences between reflected coherence waves. In this paper, we propose effective speckle reduction method that uses wavelet transform. With wavelet domain image, sub-windowing and thresholding are performed. Finally, speckle reduction experiments for Misgurnus mizolepis skin and rat eye images are shown.

Parameter Estimation for Vector Control of Induction Motors without Speed Sensors (속도센서 없는 유도전동기 백터제어 시스템의 파라메타 추정)

  • Kim, Sang-Uk;Kwon, Young-Gil;Kim, Young-Jo;Kim, Young-Seok
    • Proceedings of the KIEE Conference
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    • 1997.07f
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    • pp.2088-2090
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    • 1997
  • This paper consists of the speed sensorless vector control of induction motors with the estimation of rotor resistance. In the application of variable-speed induction motor drives, if an inaccurate rotor resistance is used because the rotor resistance can change due to skin effects and temperature variables, it is difficult to achieve a collect field orientation. In this paper, to overcome these difficulties adaptive algorithm is designed for rotor resistance identification. The proposed adaptive algorithm for rotor resistance estimation in the synchronous reference frame is applied by sliding mode current controller satisfing persistent excitation(PE) condition. Adaptive flux observer is here used for the purpose of estimating rotor flux and speed in the speed sensorless scheme. Computer simulations are carried out to verify the validity of the proposed algorithm.

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Assay of Trace Gold Ion in a Skin Cell Using a Stripping Voltammetry

  • Ly, Suw-Young;Lee, Jin-Hui;Yi, Jae-Hun
    • Journal of the Korean Applied Science and Technology
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    • v.28 no.1
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    • pp.15-21
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    • 2011
  • Threelectrodes systems were used in stripping voltammetry (SW) and cyclic voltammetry (CV) instead of the expensive platinum and Ag/AgCl reference electrodes. Moreover, the electrolyte solution was used with deep seawater, which can reduce water pollution, is more eco-friendly, and has a lower cost. The analytical optimum parameters measured via CV and SW and with working ranges were obtained from 10 to 80 ug/L using fluorine immobilized on a graphite pencil electrode (FE). Under the optimum conditions, the analytical detection limit of 6.30 ug/LAu was obtained. The results of the study can be applied to diagnostic assay for natural minerals and human finger tissue.

Percutaneous Absorption of Ketoprofen from Gel Preparations (케토프로펜 겔제제로부터 약물의 경피흡수)

  • Tan, Hyun-Kwang;Chi, Sang-Cheul;Jun, H.Won
    • Journal of Pharmaceutical Investigation
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    • v.24 no.1
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    • pp.11-16
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    • 1994
  • In order to reduce the systemic side effects and gastrointestinal irritation of ketoprofen after its oral administration, it was formulated as a 3% ketoprofen gel (ID-GEL) with Pluronic F-127. The pharmacokinetic characteristics of ID-GEL was evaluated following its transdermal application on the dorsal skin of rats at the dose of 9 mg/kg in reference to those of existing 3% ketoprofen gels. Even though the maximum concentration of 810 ng/ml was reached at 6 hrs postdose, the plasma concentration was kept almost constant until 24 hrs postdose, which suggested that ketoprofen was released continuously from the gel during this period. The bioavailability of ID-GEL was two times higher than those of existing 3% ketoprofen gels, based on the calculated area under the plasma concentration-time curves after the percutaneous administration.

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Tyrosinase Inhibitory Activity of 80 Plant Extracts (II)

  • Kim, Soo-Jin;Heo, Moon-Young;Son, Kun-Ho;Kim, Hyun-Pyo
    • Biomolecules & Therapeutics
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    • v.11 no.1
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    • pp.5-7
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    • 2003
  • The purpose of this study was to evaluate tyrosinase inhibitory activity of plant for extracts for cosmetic use. When 80 plant extracts were tested, the methanol extracts of Allium thunbergi, Asparagus oligoclonos, Ixeris dentate, Salvia plebeia, Sophora flavescens and Sophora japonica showed more than 30% inhibition of mushroom tyrosinase activity at 100 $\mu\textrm{g}$/mL. Although less active than the reference compound, kojic acid ($IC_{50}$=7.0-16.3 $\mu\textrm{g}$/mL), these plant extracts may be used as tyrosinase inhibitors in cosmetics.