• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2005년도 제30회 춘계학술대회
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• pp.35-38
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• 2005

국내의 MR영상 기술에 있어서 피부영상 및 MR Microscopy에 대한 연구는 있었지만 그 성과는 크게 만족스럽지 못했다. 본 연구는 고해상도 피부 영상을 얻기 위한 Surface coil을 구상하여 제작하고 임상용 MRI 시스템에서 영상을 얻었다. 그러나, 이러한 초기 영상으로부터 시작하여 피부영상 및 미세구조 영상을 얻는 데는 상당한 기술적 제한이 따른다. 기존의 volume형 RF coil보다 surface coil이 비록 자기장 균질도는 떨어지나 우수한 SNR을 얻을 수 있어, 개선의 방향을 coil의 형태를 조정함으로써 고해상도의 영상을 얻을 수 있다. 따라서 Surface coil 제작의 그 첫 단계인 surface coil의 구조에 따른 자기장 분포를 시뮬레이션함으로써 surface coil을 제작하는데 있어 주요 참고자료가 될 것이다.

• Journal of Pharmaceutical Investigation
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• 제37권6호
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• pp.359-364
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• 2007

Pine bark extract is well-known as a very powerful antioxidant, anti-inflammatory, and antibiotic material. French maritime pine bark extract ($Pycnogenol^{(R)}$) of Horphag Research has monopolized the world market over 30 years. Korean red pine bark extract ($Pinexol^{(R)}$) was first manufactured by the patent technology of NutraPharm in Korea in 2006. Feasibility of topical gel and patch formulations of Pinexol was systematically investigated by evaluating the skin absorption of catechin as a reference compound. In vitro hairless mouse skin absorption of catechin from gel formulation was higher than that from patches. However, significant amount of catechin was also deposited inside the skin from patch formulations, which were dependent on the types of pressure sensitive adhesives. Thus, it seems to be feasible to control the topical delivery of Pinexol by using both gel and patch formulations, and be necessary to conduct further systematic investigation.

• 한국임상수의학회지
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• 제24권2호
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• pp.276-279
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• 2007

A 2-year-old male, 3 kg body weight Japanese Chin was injured in the automobile accident three months ago. The dog became antebrachiocarpal joint instability, and performed pancarpal arthrodesis using 3 K-wires in localanimal hospital. But, the result was failure. Therefore the dog was referred to Chonbuk Animal Medical Center, Chonbuk National University. In physical examination, right carpal joint instability, knuckling sign and pain were evident. In radiography, sclerosis was observed on the 4th carpal bone. Complete blood count (CBC), serum chemistry and urinalysis finding were within reference ranges. Pancarpal arthrodesis was re-performed using 7-hole plate. However, mild skin and muscle defects was appeared by skin tension of extremity. We expected that granulation would fill the defect, but inflammation was continued on the lesions for 3 days. So, operation which is filling it was done by using the muscle flap and tubed skin flap. The donor muscles were flexor carpi radialis and superficial digital flexor muscles. After 7 days, the muscle flap was survived, but tubed skin flap was necrosed. After 20 days, the skin defect was substituted with granulation tissues. The flexor carpi radialis muscle and superficial digital flexor muscle transposition can be a useful procedure for reconstructing soft tissue defects in the carpal and metacarpal areas.

• 셀메드
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• 제11권1호
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• pp.2.1-2.8
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• 2021

The clinical condition Amnesia causes difficulty in learning new information and the inability to recall past events. It is primarily concerned with recent memory loss. Majoon-e-Nisyan (MJN) is a polyherbal Unani formulation, present in a semi-solid form. It is widely used potent drug of the Unani System of Medicine (USM) for treating Nisyan (amnesia). In the present study polyherbal Unani formulation, MJN has been studied for its quality control and acute toxicity. Standardization (quality control) of drugs deals with drug identity, drug quality and purity determination. Standardization of MJN had been done as per the Unani pharmacopoeial parameters approved by World Health Organization (WHO) - Pharmacognostical parameters, Physico-chemical parameters, high-performance thin-layer chromatography (HPTLC), microbial load, aflatoxin, and heavy metals. Solvents and chemicals used in the study were of analytical grade and used instrument were calibrated. By conducting an acute oral toxicity study in rats, the safety of MJN was assessed. The limit test method of OECD guideline 425 was followed in the study. Results of standardization and standard operating procedures (SOPs) for preparation of MJN may serve as the standard reference in the future. The data generated in the study for the quality control of MJN proved the quality of formulation and shows that MJN is not toxic in rats following acute dosing up to 2000 mg/kg bw. The data obtained in the paper for MJN may be used as a standard guideline for preparation of the formulation which can save time, cost, and resources for future research endeavours.

• 한국의류산업학회지
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• 제25권2호
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• pp.248-254
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• 2023

This study aims to measure the skin rigidity of different facial areas among Koreans and propose guidelines for each area's skin rigidity that can be applied with a facial robot for testing respiratory protective devices. The facial skin rigidity of 40 participants, which included 20 men and 20 women, aged 20 to 50, was analyzed. The rigidity measurement was conducted in 13 facial areas, including six areas in contact with the mask and seven non-contact areas, by referring to the facial measurement guidelines of Size Korea. The facial rigidity was measured using the Durometer RX-1600-OO while in a supine position. The measurement procedure involved contacting the durometer vertically with the reference point, repeating the measurement of the same area five times, and using the average of three values whose variability was between 0.4 and 4.2 Shore OO. The rigidity data analysis used precision analysis, descriptive statistics analysis, and mixed-effect ANOVA. The analysis confirmed the rigidity of the 13 measurement areas, with the highest rigidity of the face being at the nose and forehead points, with values of 51.2 and 50.8, respectively, and the lowest rigidity being at the chin and center of the cheek points, with values of 19.2 and 20.7, respectively. Significant differences between gender groups were observed in four areas: the tip of the nose, the point below the chin, the area below the lower jaw, and the inner concha.

• 한국임상수의학회지
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• 제40권5호
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• pp.382-386
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• 2023

A 2-year-old, 12.5 kg, castrated male, mixed-breed dog was presented with a 1-year history of pruritus and progressive alopecia. On physical examination, no remarkable findings were detected including body condition score (5/9). A dermatological examination of the dog revealed generalized erythema, papules or plaques, especially on the face, auricle, dorsum, and shoulder. A fine-needle aspiration of the dorsum and face lesions revealed various numbers of macrophages with foamy cytoplasm and multinucleated giant cells. A bacterial culture test showed the growth of Staphylococcus pseudintermedius. A complete blood cell count was unremarkable and biochemical abnormalities included hyperglobulinemia (4.8 g/dL, reference interval 2.5-4.5 g/dL), mild hypertriglyceridemia (277 mg/dL, reference interval 10-100 mg/dL) and mild hypercholesterolemia (383 mg/dL, reference interval 110-320 mg/dL). Additional diagnostic tests were performed to identify the underlying cause of hyperlipidemia. Canine pancreatic lipase immunoreactivity (<50 ng/mL, reference interval 0-200 ng/mL) and total T4 (1.4 ㎍/dL, reference interval 1.1-5.6 ㎍/dL) were within the reference intervals. For a definitive diagnosis, skin biopsy specimen was collected from the papular lesions on the dorsum by using a 4 mm biopsy punch. A histopathological examination revealed numerous large macrophages with abundant foamy cytoplasm in the dermis. The foamy macrophages were located diffusely between the collagen fibers. Extracellular amorphous lipid deposits were also presented in the dermal tissue. A definitive diagnosis of cutaneous xanthoma was made based on clinical signs and cytological and histopathological results.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 2003년도 ISIS 2003
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• pp.632-635
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• 2003

This paper describes a system fur tracking multiple faces in an input video sequence using facial convex hull based facial segmentation and robust hausdorff distance. The algorithm adapts skin color reference map in YCbCr color space and hair color reference map in RGB color space for classifying face region. Then, we obtain an initial face model with preprocessing and convex hull. For tracking, this algorithm computes displacement of the point set between frames using a robust hausdorff distance and the best possible displacement is selected. Finally, the initial face model is updated using the displacement. We provide an example to illustrate the proposed tracking algorithm, which efficiently tracks rotating and zooming faces as well as existing multiple faces in video sequences obtained from CCD camera.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제3권1호
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• pp.87-92
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• 2003

This paper describes a system for tracking multiple faces in an input video sequence using facial convex hull based facial segmentation and robust hausdorff distance. The algorithm adapts skin color reference map in YCbCr color space and hair color reference map in RGB color space for classifying face region. Then, we obtain an initial face model with preprocessing and convex hull. For tracking, this algorithm computes displacement of the point set between frames using a robust hausdorff distance and the best possible displacement is selected. Finally, the initial face model is updated using the displacement. We provide an example to illustrate the proposed tracking algorithm, which efficiently tracks rotating and zooming faces as well as existing multiple faces in video sequences obtained from CCD camera.

• Imaging Science in Dentistry
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• 제39권4호
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• pp.195-198
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• 2009

Purpose : To establish reference doses of periapical radiography in Chonnam Province, Korea. Materials and Methods : The target-skin distances were measured for dental patient's 1235 exposures including 345 mandibular molar areas. Each periapical radiation exposure was simulated with exactly the same patients exposure parameters and the simulated radiation doses were measured utilizing Mult-O-Meter (Unfors Instruments, Billadal, Sweden). The measurements were done in 44 dental clinics with 49 dental x-ray sets in Chonnam Province for one or two weeks at each dental clinic during year 2006. Results : The third quartile patient surface doses were 2.8 mGy for overall periapical exposures and 3.2 mGy for periapical mandibular molar exposures. Conclusion : The third quartile patient surface doses in Chonnam Province can be used as a guide to accepted clinical practice to reduce patient radiation exposure for the surveyed reference doses were below the recommended dental periapical radiography dose of 7 mGy by IAEA.

• Clinical and Experimental Pediatrics
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• 제50권2호
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• pp.209-212
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• 2007

장병성 선단 피부염은 위장관에서 아연 흡수가 제대로 되지 않아 발생하는 질환으로서 주로 이유기의 영 유아에 호발하고 상염색체 열성 유전하는 질환이다. 홍반, 인설, 가피, 건선양 피부와 습진의 특징적인 피부 병변이 개구부와 사지 말단 부위에 대칭적으로 나타나고, 만성 설사, 탈모증, 조갑 주위염, 그리고 성장 장애가 나타나는 드문 질환이다. 혈중 아연 농도가 대부분에서 떨어져 있지만 정상 혈중 농도에서도 말초 조직 내의 아연 농도가 떨어지면 증상이 나타난다. 다른 원인 질환이 없고 만삭으로 정상 분만한 모유 수유 영아에서 조직학적으로 일치하며, 혈중 아연 농도는 정상이지만 모발에서 아연 농도가 떨어진 장병성 선단 피부염 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.