• Applied Microscopy
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• 제1권1호
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• pp.19-26
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• 1969

개구리(Rana temperaria) 상피조직의 세포간 접착부위를 전자현미경으로 관찰하였다. 새로운 절편방법을 시도하여 동 부위의 초미세구조를 밝혔으며, 세가지 세포간간 접착방법중 하나인 데스모솜(Desmosome)은 상피세포 원형질막을 따라 절서있고 빈번하게 배열되어 있음을 처음으로 밝혀냈다. 본 연구 및 관찰결과와 관련하여 피부 암세포의 성장기 전 과의 관계를 논의하였다.

• Steel and Composite Structures
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• 제45권3호
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• pp.467-482
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• 2022

One of the major failure modes in composite sandwich structures is the separation between skins and core. In this study, the effect of employing foam filled composite corrugated core on the skin/core debonding (resistance to separation between skin and core) is investigated both experimentally and numerically. To this aim, triangular corrugated core specimens are manufactured and compared with reference specimens only made of PVC foam core in terms of skin/core debonding under bending loading. The corrugated composite laminates are fabricated using the hand layup method. Also, the Vacuumed Infusion Process (VIP) is employed to join the skins to the core with greater quality. Utilizing an End Notched Shear (ENS) fixture, three point bending tests are performed on the manufactured sandwich composite panels. The results reveal that the resistance to separation capacity and flexural stiffness of sandwich composite has been increased about 170% and 76%, respectively by using a triangular corrugated core. The Cohesive Zone Model (CZM) with appropriate cohesive law in ABAQUS finite element software is used to model the progressive face/core interfaces debonding the difference between experimental and numerical results in predicting the maximum born load before the skin/core separation is about 6 % in simple core specimens and 3% in triangular corrugated core specimens.

• KIEAE Journal
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• 제15권3호
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• pp.43-48
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• 2015

Purpose: Recently, many countries around the world are actively looking for the ways to make full use of natural energy sources and also develop and apply an environmentally friendly system designed to save building energy consumption. Under these circumstances, this study intended to determine the applicability and energy saving effect by deriving the indoor thermal performance characteristics and the PCM temperature appropriate for a double skin façade to reduce indoor energy consumption through the application of different PCM temperatures to double skin façade and perform a performance evaluation depending on the application or non-application of PCM to a double skin façade. Method: For this study, the physical variables of the double skin façade with PCM were configured through a preliminary examination based on an experimental measurement, and experimental measurements were taken with a total of 7 types of mockup cases: Type-1 (Basic), the basic double skin façade, Type-2 (PCM $18^{\circ}C$) which was applied to the inner skin of the double skin façade depending on the phase-change temperature of PCM, Type-3 (PCM $20^{\circ}C$), Type-4 (PCM $22^{\circ}C$), Type-5 (PCM $24^{\circ}C$), Type-6 (PCM $26^{\circ}C$), and Type-7 (PCM $28^{\circ}C$) with reference to the data analysis of the basic double skin façade which preceded this study, to analyze the indoor thermal performance of the double skin façade depending on PCM temperature and the installation or non-installation of a double skin façade applying PCM based on the selected unit space. Result: Indoor thermal performance was analyzed depending on the PCM temperature applicable to double skin façade, and the analysis of heating energy reduction showed that Type-2 (PCM $18^{\circ}C$) gained 15.9% more heat compared with Type-1 (Basic) and secondly, Type-3 (PCM $20^{\circ}C$) gained 11.5% more heat. Based on these findings, it is deemed possible that the use of energy for heating can be reduced when heat coming indoors increases during the heating period, and the appropriate temperature for PCM applied to the inner skin of a double skin façade to reduce heating energy in winter, Type-2 (PCM $18^{\circ}C$) showed the highest efficiency and Type-3 (PCM $20^{\circ}C$) was also deemed appropriate.

• 대한방사선기술학회지:방사선기술과학
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• 제32권1호
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• pp.39-43
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• 2009

전리방사선을 이용한 의료진단검사는 장치의 발전과 더불어 환자의 삶을 개선시키고 의료검사의 혁명을 가지고 왔다. 하지만 이러한 의료영상의 발전은 대중에 의한 전리방사선피폭의 증가의 원인이 되었다. 이러한 가운데 ICRP에서는 각 국가 및 지역의 실정에 맞게 진단참고준위를 사용하도록 권고하고 있으며, 우리나라에서도 2007년 식품의약품안전청에서 환자선량측정 가이드라인을 제시하였다. 하지만 임상에서는 대부분 선량계가 없어 X선 검사시 환자피부선량을 알 수가 없는 것이 현실이다. 이에 저자는 bit system을 이용하여, PC상에서 엑셀프로그램을 이용하여 간단하게 환자선량을 알 수 있게 프로그램화 하여 그 유용성을 검토하였으며, 그 결과 실측값과 계산값은 약 10% 정도의 차이로 우수한 결과를 나타내었다.

• 대한의용생체공학회:의공학회지
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• 제29권6호
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• pp.493-501
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• 2008

In this paper, a novel system is proposed to measure skin hydration using the susceptance method. This system largely consists of a low-voltage(${\pm}2.6$ V) driven circuit and minimized electrodes of size($5{\times}5mm^2$). To evaluate the accuracy of the novel system in measuring skin hydration, skin hydration values from 105 subjects are measured by the proposed system. The measurements are then compared to those obtained by the golden reference device based on the capacitance method in terms of Intraclass Correlation Coefficient(ICC) and correlation coefficient. All measurements are performed on 7 sites, which are forehead, Crow's foot, cheek, chin, volar forearm, dorsal forearm, and back of the hand, in a room where the temperature and humidity are maintained at an uniform level of $22{\pm}2^{\circ}C$ and $50{\pm}5%$, respectively. ICC values are above 0.9(p=0.001), signifying that the skin hydration values measured by the two methods show a good level of reliability. Correlation coefficient between the two methods is also 0.562(p=0.001). Based on these results, it is expected that the proposed system may be applicable in a variety of clinical or cosmetic areas.

• Journal of Animal Science and Technology
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• 제62권2호
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• pp.141-158
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• 2020

Skin is a major thermoregulatory organ in the body controlling homeothermy, a critical function for climate adaptation. We compared genes expressed between tropical- and temperate-adapted cattle to better understand genes involved in climate adaptation and hence thermoregulation. We profiled the skin of representative tropical and temperate cattle using RNA-seq. A total of 214,754,759 reads were generated and assembled into 72,993,478 reads and were mapped to unique regions in the bovine genome. Gene coverage of unique regions of the reference genome showed that of 24,616 genes, only 13,130 genes (53.34%) displayed more than one count per million reads for at least two libraries and were considered suitable for downstream analyses. Our results revealed that of 255 genes expressed differentially, 98 genes were upregulated in tropically-adapted White Fulani (WF; Bos indicus) and 157 genes were down regulated in WF compared to Angus, AG (Bos taurus). Fifteen pathways were identified from the differential gene sets through gene ontology and pathway analyses. These include the significantly enriched melanin metabolic process, proteinaceous extracellular matrix, inflammatory response, defense response, calcium ion binding and response to wounding. Quantitative PCR was used to validate six representative genes which are associated with skin thermoregulation and epithelia dysfunction (mean correlation 0.92; p < 0.001). Our results contribute to identifying genes and understanding molecular mechanisms of skin thermoregulation that may influence strategic genomic selection in cattle to withstand climate adaptation, microbial invasion and mechanical damage.

• 전자공학회논문지SC
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• 제42권6호
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• pp.67-76
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• 2005

본 논문에서는 근전의수용 소형 근전위 센서를 제안한다. 근전의수용 근전위 센서를 의수 소켓에 내장시키기 위해서는 소형이어야 한다. 제안된 근전위 센서는 피부와 접촉하는 전극과 신호처리를 위한 회로부가 일체화된 형태로 소형화 하였다. 기준 전극은 두 입력전극의 가운데에 나란히 배치되고, 입력전극은 막대형, 기준전극은 막대형과 원형의 두 가지 형상으로 설계하였다. 두 입력전극 사이의 간격은 근섬유의 근전위 신호의 전도속도와 중심주파수를 고려하여 18mm, 20mm, 22mm 의 세 개의 서로 다른 간격을 가진 전극을 제작하였다. 사용된 전극의 재료는 땀이나 습기에 강한 SUS440 금속을 사용하였다. 신호처리 회로부는 대역통과 필터를 갖는 차동 증폭기, 전원노이즈를 제거하기 위한 대역저지 필터, 교류결합증폭기, 절대평균값 회로로 구성되어 있다. 실험에서는 정상인의 전완에서 근전위 신호를 취득하여 주파수 분석하고, 입력전극 사이의 간격과 기준전극의 형상에 따른 출력특성 평가하였다. 본 논문에서는 실험의 결과로부터 두 입력전극간의 거리가 18mm 이면서, 입력전극의 형상과 기준전극의 형상이 모두 막대형인 표면 근전위 센서가 근전의수에 최적임을 보인다.

• 셀메드
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• 제10권3호
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• pp.20.1-20.6
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• 2020

The Karafs is a dried herb of whole plant of Apium graveolens L. from Apiaceae (carrot family). The seeds (fruits) of Apium graveolens are known as Tukhm-e- Karafs in Unani Medicine. Karafs is known as Celeri in French, Apio in Spanish, Selderiji in Dutch, Syelderey in Russian and Chin in Chinese. It is cultivated in different parts of the world for its seeds as spice and green leaves and root as salad crop. Its seeds are also used for medicinal purposes in complementary and alternative medicines. In Unani it is used as a single drug or as an ingredient in compound formulations used for management in various ailments. The seeds have various pharmacological actions like hepatoprotective, diuretic and lithotriptic etc. It is commonly found in Western Asia, Europe, North Africa and various parts of India like Punjab, Uttar Pradesh and Himachal Pradesh etc. In Unani its actions are described as Mudirr-i-Bawl (Diuretic), Mufattit-i-Hasāh (Lithotriptic), Dafi'-i-Tashannuj (Antispasmodic) and Kāsir-i-Riyāh (Carminative). It is used for the treatment of Hasah al-Kulya (Nephrolithiasis), Nafkh al-Mi'da (Flatulence), Istisqā' (Oedema) and Ihtibās al-Bawl (Retention of urine) etc.

• 한국의류산업학회지
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• 제8권2호
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• pp.214-224
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• 2006

Computer graphics mean a reproduction of various information through image processing or the technology that is widely thought in makeup areas also, recently. Especially, Adobe Illustrator, unlike Adobe Photoshop used in image editing and correction, is software suitable for image drawing and reproducing beauty makeup. Beauty makeup is a work adorning human body to fit to the aesthetic standard in that period, and is a plastic art expressing shapes, colors and textures using design elements. Adobe Illustrator is a 2D graphics designing images using shapes having plane colors. In this study I studied techniques reproducing each element of contours and colors of beauty makeup through Adobe Illustrator CS. In other words, I have prepared a reference data by studying techniques reproducing beauty makeup using Adobe Illustrator CS. In this study, though, I couldn't try various things, because I limited facial contour and skin color to only one kind. Therefore, I hope, in the future, others can expand the ethnics of using Adobe Illustrator in more enriched ways by working on various facial contours and skin colors.

• 셀메드
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• 제10권2호
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• pp.16.1-16.8
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• 2020

Standardization of drug deals with confirmation of drug identity and determination of drug quality and purity. Unani herbal formulations are used in traditional medicine for the treatment of various diseases. Cancer is a disease which causes abnormal, uncontrolled growth of body tissue or cells, which tend to proliferate in an uncontrolled way. Spread of cancer from site of origin to other organs of the body is called metastasis. It is a hyper proliferative disorder involving, transformation, dysregulation of apoptosis, invasion and angiogenesis. The present study aimed to standardize a classical Unani formulation (CUF) described as anticancer properties. The CUF has been used for anti-cancerous activity (Dāfi'-i-saraṭān) in human population by Unani physicians for centuries. The standardization parameters carried out for classical Unani formulation are pharmacognostical studies, physicochemical parameters, high-performance thin layer chromatography (HPTLC), microbial load, aflatoxins, and heavy metals revealing specific identities and to evaluate Pharmacopoeial standards. Experiment and the data obtained established the Pharmacopoeial standards for this formulation for identification and quality control purpose. The CUF has been successfully standardized and standard operating procedures (SOPs) for its preparation has been laid down which may serve as a standard reference in future. The standardization data of this formulation may be used as a standard guideline for preparation of the formulation in future.