• Journal of Sasang Constitutional Medicine
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• v.24 no.3
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• pp.60-68
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• 2012

Objectives Sasang Constitution (SC) is determined by various physical and psychological attributes. Recently, skin properties have been used effectively to describe SC types in clinics. In this paper, we investigated the constitution dependence of skin elasticity and skin perspiration by using quantitative measurement devices. Methods The skin elasticity of forearm and the skin perspiration of forehead and philtrum were measured in 223 elderly female subjects. To determine the subject's constitution, we adopted the classification results from a newly developed diagnostic tool. For the clarity of constitution, we excluded low-scored subjects in their SC classification. Results & Conclusions As a result, the elasticity hysteresis of forearm (EHFa) of Taeum-in group was significantly less than the EHFa of Soeum-in group. Soeum-in group has high perspiration difference between philtrum and forehead (Diff.PhFh) compared to Taeum-in group in a significance level of .05. Taeum-in and Soeum-in group were significantly classified by EHFa and Diff.PhFh using a Support Vector Machine.

• Korean Journal of Oriental Medicine
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• v.18 no.3
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• pp.119-126
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• 2012

1. Objectives Sasang constitutional medicine is unique in Korean traditional medicine. It diagnoses and treats patients based on his/her Sasang constitution (SC). Skin properties have been used as an effective diagnostic component in the classification of SC types in clinics. In this paper, we investigated the SC-based health relevance of skin elasticity and wrinkle properties. 2. Methods The skin elasticity and wrinkle of forearm and dorsal hand were measured in 299 elderly female subjects. To determine the subject's Sasang constitution, we adopted the classification results from a newly developed SC diagnostic tool. The health states of the subjects were scored by two Korean traditional medical doctors, by whom each subject was categorized either into the healthy state or the unhealthy state. 3. Results As a result, the elasticity hysteresis of forearm (E_HYS), the visco-elasticity (VE_MEAN), and the wrinkle frequency energy of backhand (W_HAND) showed significant differences between Taeum-in group and Soeum-in group. In case of the Soeum-in on unhealthy state, VE_MEAN was decreased significantly (p<.05). W_HAND and W_ARM_H of the healthy Taeum-in were less than those of the unhealthy Taem-in. 4. Conclusions In this study we showed that, for an elderly female population, skin elasticity and viscosity were significantly different not only between each SC type but also between healthy group and unhealthy group in each constitution. In particular, Soeum-in subjects were inferred to be superior in retaining skin softness when they were healthy, and Taeum-in subjects were easy to lose their firmness of skin surface when they became unhealthy.

• Composites Research
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• v.30 no.3
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• pp.181-187
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• 2017

The effect of nanoscopic and microscopic Fe, $Fe_3O_4$, and Ni particles and their shapes and substrate materials on the heating behavior of thermoplastic polyurethane (TPU) adhesive films was investigated via induction heating. The heat generation tendency of $Fe_3O_4$ particles was higher than that shown by Fe and Ni particles in the TPU adhesive films. When the Fe and Ni particle size was larger than the penetration skin depth, the initial heating rate and maximum temperature increased with an increase in the particle size. This is attributed to the eddy current heat loss. The heating behavior of the TPU films with Ni particles of different shapes was examined, and different hysteresis heat losses were observed depending on the particle shape. Consequently, the flake-shaped Ni particles showed the most favorable heat generation because of the largest hysteresis loss. The substrate materials also affected the heating behavior of the TPU adhesive films in an induction heating system, and the thermal conductivity of the substrate materials was determined to be the main factor affecting the heating behavior.

• Steel and Composite Structures
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• v.27 no.5
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• pp.577-598
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• 2018

The imperfect steel-concrete interface bonding is an important deficiency of the concrete-filled double skin tubular (CFDST) columns that led to separating concrete and steel surfaces under lateral loads and triggering buckling failure of the columns. To improve this issue, it is proposed in this study to use longitudinal and transverse steel stiffeners in CFDST columns. CFDST columns with different patterns of stiffeners embedded in the interior or exterior surfaces of the inner or outer tubes were analyzed under constant axial force and reversed cyclic loading. In the finite element modeling, the confinement effects of both inner and outer tubes on the compressive strength of concrete as well as the effect of discrete crack for concrete fracture were incorporated which give a realistic prediction of the seismic behavior of CFDST columns. Lateral strength, stiffness, ductility and energy absorption are evaluated based on the hysteresis loops. The results indicated that the stiffeners had determinant role on improving pinching behavior resulting from the outer tube's local buckling and opening/closing of the major tensile crack of concrete. The lateral strength, initial stiffness and energy absorption capacity of longitudinally stiffened columns with fixed-free end condition were increased by as much as 17%, 20% and 70%, respectively. The energy dissipation was accentuated up to 107% for fixed-guided end condition. The use of transverse stiffeners at the base of columns increased energy dissipation up to 35%. Axial load ratio, hollow ratio and concrete strength affecting the initial stiffness and lateral strength, had negligible effect of the energy dissipation of the columns. It was also found that the longitudinal stiffeners and transverse stiffeners have, respectively, negative and positive effects on ductility of CFDST columns. The conclusions, drawn from this study, can in turn, lead to the suggestion of some guidelines for the design of CFDST columns.

• Journal of Pharmaceutical Investigation
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• v.32 no.4
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• pp.291-297
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• 2002

For preventing and curing the stretching mark, TECA Niosome/W/O system creams were formulated using Titrated Extract of Centella Asiatica (TECA) which is well known for its excellent wound healing effect. The lipid-water partition coefficients and the stabilities of TECA were evaluated and TECA Niosome/W/O system (TECA N/W/O) creams were prepared with different concentrations of cetyl alcohol and ceramide. TECA N/W/O cream was evaluated with respect to their rheological properties, permeation through excised skin of hairless mouse and in vitro and in vivo accumulation in the skin of hairless mouse. In addition, dermal thicknesses of hairless mouse skins were determined following the in vivo application of TECA N/W/O cream and control cream. TECA N/W/O creams showed pseudoplastic flow and hysteresis loop. The permeation of TECA from formulations through excised skin of hairless mouse did not observed. Amount of accumulated drug in the excised skin of hairless mouse was deσeased with an increase in the concentration of cetyl alcohol and showed no relationship with concentration of ceramide. Amount of accumulated drug in formulation A-3 was higher than in niosome suspension and other formulations. In in vivo experiment, amount of accumulated drug in formulation A-2 and A-3 was much higher than that of niosome suspension. Being treated with the N/W/O cream for 8 weeks, the dermal thickness of hairless mouse skin was increased 3.2 times than that of 16 weeks-control group.

• Journal of Pharmaceutical Investigation
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• v.35 no.3
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• pp.165-171
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• 2005

Itraconazole is a triazole antifungal agent to inhibit most fungal pathogens. However, it is difficult for itraconazloe to be delivered by topical system due to its poor aqueous solubility. First, niosomes containing drug were prepared with span 60, cholesterol. tocopherol and poloxamer 407 as vesicle forming agents in an effort to increase solubility of itraconazole. And then prepared niosomes were dispersed in O/W creams (containing xanthan gum, glycerin, vaseline, glyceryl monostearate and $Cerix^{\circledR}-5$) or gels (containing xanthan gum and poloxamer 407). Both creams and gels were evaluated with respect to their rheological properties, in vitro permeation through excised skin of hairless mouse. Creams or gels containing niosome showed pseudoplastic flow and hysteresis loop. For both creams and gels, viscosity was increased with increasing the content of glycerine or vaseline and the content of gel forming polymer, respectively. In creams, the permeability of drug to skin was decreased with increasing the viscosity of cream. The permeability of drug was affected by pH as well as viscosity of gel. In vitro permeation test results demonstrated that cream formulations showed better permeability than gels. In conclusion, these results suggest that creams formulation containing niosome can be useful for the topical delivery of intraconazole.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.339-341
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• 2007

Soft ferromagnetic materials are very useful for many sensors using magnetic materials with high permeability, low coercivity and low hysteresis loss. Among them, FeCoSiBNi amorphous magnetic films show us a good impedance change(about 3.05%/Oe, at 12MHz) by the exterior magnetic field in this experiment. These are produced by rapid solidification from the melt and the material is ejected in a jet from a nozzle and quenched in a stream of liquid. After that, we make them a shape of wire with different sizes of width. Thus, we can find that the impedance change (122.16%, at 12MHz) is occurred and the fabricated magnetic wire has the characteristics of good sensor element.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.26 no.9
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• pp.669-676
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• 2013

In this study, we introduce a polymer(polyimide) based pressure sensor to measure real-time heart beat and blood pressure. The sensor have been designed with consideration of skin compatibility of material, cost effectiveness, manufacturability and wireless detection. The designed sensor was composed of inductor coils and an air-gap capacitor which generate self-resonant frequency when electrical source is applied on the system. The sensor was obtained with metalization, etching, photolithography, polymer adhesive bonding and laser cutting. The fabricated sensor was shaped in circular type with 10mm diameter and 0.45 mm thickness to fit radial artery. Resonant frequencies of the fabricated sensors were in the range of 91~96 MHz on 760 mmHg pressurized environment. Also the sensor has good linearity without any pressure-frequency hysteresis. Sensitivity of the sensor was 145.5 kHz/mmHg and accuracy was less than 2 mmHg. Real-time heart beat measurement was executed with a developed hand-held measurement system. Possibility of real-time blood pressure measurement was showed with simulated artery system. After installation of the sensor on skin above radial artery, simple real blood pressure measurement was performed with 64 mmHg blood pressure variation.

• Journal of Sensor Science and Technology
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• v.16 no.5
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• pp.389-393
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• 2007

Soft ferromagnetic materials are very useful for many sensors using magnetic materials demanding high permeability, low coercivity and low hysteresis loss. Among them, FeCoSiBNi amorphous magnetic films show a good impedance change (about 5.01 %/Oe, at 10 MHz) by the exterinal magnetic field in this experiment. The magnetic films are produced by melt-spun method, one of the rapid solidification process. Ribbon shape wires were made from the films, and let them annealed in DC magnetic field to increase the maximum Giant Magneto Impedance ratio. Field annealing decreases the stress and changes the effective anisotropy. Thus, we can find that the impedance change (200.47 %) is improved and the fabricated magnetic wire has characteristics of good sensor element.

• Journal of the Korean Society of Clothing and Textiles
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• v.34 no.1
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• pp.92-101
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• 2010

This study reports on the development of intelligent clothing using a shape memory alloy (SMA) that forms a still air layer and provides thermal insulation depending on the environment temperature. SMA springs were prepared with Nitinol and have an original length of 6mm and a latent length of 20mm with a response temperature of $24.5^{\circ}C$. Hysteresis was evaluated at a temperature between $0^{\circ}C$ and $40^{\circ}C$. An experimental outdoor jacket that was attached with 30 springs was compared with a commercial jacket in terms of the microclimate temperature, humidity, and comfort properties by human subject tests in the microclimate chamber set at $5{\pm}0.5^{\circ}C$. The results showed that the microclimate temperature of SMA embedded clothing system from the wear trials was higher than the commercial ones during the rest period after exercise, especially on the skin side. In addition the thermal, humidity, and comfort sensations of SMA embedded clothing were better than the commercial ones.