• 대한한의학회지
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• 제38권4호
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• pp.62-81
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• 2017

Objectives: As interests in the beauty of skin is growing continuously, more people are focusing on white and clean skin. Melanin is the major factor that determines skin color. The abnormal concentration of melanin causes various skin diseases such as vitiligo, freckles, and melasma. This study investigated the inhibitory effect of Eriobotryae Folium extracts (EF) with phreatic water (PW) on the melanin synthesis. Methods: The effect of EF on melanin synthesis was evaluated by using mouse melanoma cells (B16F10). To define the mechanisms, real-time PCR and western blot were used. We also evaluated the inhibitory effects of EF and PW on melanin synthesis by using HRM-2 melanin-possessing hairless mice. After UVB irradiation, melanin differences between the skin parts that were treated and untreated with EF and PW. Levels of mRNA were measured by real-time quantitative PCR and histological analysis of the dorsal skin was conducted by hematoxylin and eosin staining. Results: EF inhibited various mechanisms of melanogenesis, and the effect was increased when combined with PW. In vitro experiments have shown that EF inhibited the expressions of tyrosinase related protein-1 (TRP-1) mRNA, tyrosinase mRNA, microphthalmia-associated transcription factor (MITF) mRNA and the tyrosinase inhibitory activation, but it stimulated the extracellular regulated kinase (ERK) mRNA expression. In vivo experiments have shown that EF prevented melanogenesis in the mice dorsal skin and inhibited TRP-1 mRNA expression. Also these effects were increased when combined with PW. Conclusions: EF and PW might be a new and effective treatment for whitening and treating pigmentation of skin.

• 생명과학회지
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• 제33권7호
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• pp.555-564
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• 2023

본 연구에서는 이너뷰티용 소재로서의 활용가능성을 확인하기 위하여 생물전환 가시오가피-진피 혼합추출물(B-MEAC)의 항산화 활성, 엘라스타제 억제활성 및 피부보습 효과 등을 평가하였다. B-MEAC의 항산화 활성을 측정한 결과 DPPH radical을 농도의존적으로 소거하여 SC₅₀이 156.1±0.82 ㎍/ml로 나타났다. 또한, 엘라스타제 억제활성을 측정한 결과 B-MEAC 처리 농도 의존적으로 엘라스타제 활성을 억제하는 것으로 확인되었다(p<0.001). 경구투여한 B-MEAC가 마우스 피부 보습에 미치는 영향을 확인하기 위하여 피부 수분량과 경피수분손실량을 측정한 결과 건조유도 된 대조군에 비하여 피부 수분량은 증가하고(p<0.001), 경피수분손실량은 감소하는 것으로 나타났다(p<0.01). 또한, 건조유도 된 마우스 피부의 교원섬유 변화에 미치는 영향을 Masson's trichrome 염색을 통해 관찰한 결과 B-MEAC를 투여한 군에서 콜라겐의 양이 대조군에 비해 상대적으로 증가하여 푸른색으로 보다 진하게 염색되었다. 또한, 건조유도 된 마우스 피부의 보습 기능에 미치는 영향을 확인하기 위하여 보습 관련 인자들의 발현을 Western blot 기법으로 확인한 결과 B-MEAC를 투여한 군에서 대조군에 비하여 MMP-1 단백질의 발현량은 감소하였고, COL1A1, HAS2, filaggrin, AQP3 단백질 발현량은 회복되는 것으로 나타났다(p<0.001). 따라서 B-MEAC의 보습효과는 엘라스타제 활성 억제, MMP-1 발현 감소, 콜라겐 생성 촉진, 피부 보습 관련 단백질인 HAS2 및 AQP3 발현 증가, 피부 장벽기능의 중요인자인 filaggrin 발현 증가를 통한 수분량 증가와 TEWL 감소에 의해 나타나는 것으로 이너뷰티 소재로서의 개발 가능성을 제시한다.

• 대한예방한의학회지
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• 제4권2호
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• pp.273-284
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• 2000

The objective of this study consists on clarifying what factors are influenced upon skin care behavior using fender's Health Promotion Model, widely used to anticipate practices of health care behavior for women with keen interest in skin care and then manifesting their correlations from July 1 to August 22, 1998, on 159 women interested in skin care. A subvariable included practice of skin care behavior and independent variables include general characteristics, health fitness, the level of agreement with the advantages of the perceived skin care behavior, the level of cognition of the necessity for skin care behavior The data collected processed with ANOVA and multiple regression analysis to clarify what factors among other independent variables have the most powerful effects upon skin care. The resultant findings were revealed, as follows : 1. In health care behavior among skin care behavior,'full ingestion of water' represented the highest value by 3.45 points, 2. The testees of this study had for the most part a higher level of cognition for the necessity for skin care behavior than for practice of skin care behavior. The more points they have for cognition of the necessity for skin care behavior, the more points they present for practice of skin care behavior. 3. From the perspective of the relationship between sociometic factors on the testees and their skin care behavior, the higher level married women were on (p<0.05) and the more points they have for economic status, the higher points were reflected . 4. The correlations between the testees' recognition or perception factors and points for practice of skin health state showed the higher points than the group who thought that they did not know their own skin health state (p<0.05). The higher the points of skin care fitness (p<0.0001), the higher the points of self-awareness (p<0.0001) 5. The factors that had the most powerful influence upon cognition and practice of women's skin care behavior were found, with statistical significance, to be adjustable factors such as age, smoking, drinking habit, economic status, etc. and points of cognition of the necessity for skin care behavior.

• 복식
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• 제28권
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• pp.65-84
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• 1996

The purpose of this study is to analyze the relation between the beauty of human body and the fashion illustration in each period And I attained my object through the investigation of features and changes of illustration which is given a vivid description of the features and development of ideal humam body beauty. By various methods I studied this subject. Frist I refered to sundry records Secondly I investiated the fashion illustrations which are included in Vogue. On the basis of this data I grasped the ideal types of human body beauty which is founded during the social change in each 10 years. And I analyzed the relation be-tween the ideal type and fashion illustration which show the change of fashion. The summary of result is as follows. 1. In the early part of the 20th century the beauty of human body is represented with the figure of large-sized beauty which emphasize shoulder and bust. And fashion ikllustration show 9 life-size broad shoulder full bust lim waist and hourglass silhouette. 2, In the 1910s the swell of strength vanishes gradually and shoulder and sleeve are straight type. And fashion illustration show 7 life-size high waist line. And that is tublar sil-houette of high waist and streamline shape in which bust and hip are not emphasized. 3. In the 1920s the ideal type of human body beauty is straight type which shows flat bust and unexaggerate hip. And fashion illus-tration is about 8 life-size tublar silhouette of low waist and lunger and slimmer and young style in which bust and hip are not emph-asized. 4. In the 1930s the ideal is womamly slim and long style. Fashion illustration is about 8 life-size and slim & long silhouette in which waist line is emphasized and bust and hip line come out. 5. In the 1940s the ideal type is womamly style which has narrow shoulder rich bast and slim waist. And fashion illustration is about 7 life-size and hourglass silhouette which has unartificial shoulder slim waist and empha-sized bust. 6. In the 1950s the ideal type is that of ro-bust health which emphasize build and muscu-lar system. And fashion illustration is 8.5 life-size and show full bust and made waist slimmer. That is sheath silhouette. 7. In the child who has full face with large eyeball slender and long leg: narrow and immatured body comparatively big head. And fashion illus-tration is 7 life-size and show slim and long neck flat bust long and slim limbs and big head. That is H type silhouette. 8. In the 1970s the ideal type is high stat-ure flat breast small hip and wide shoulders. And fashion illustration is wide shoulders and slim waist as 11 life-size and straight sil-houete. 9. In the 1980s the ideal type is extremely emphasized breadth of shoulder because healthy body and muscle are recognized as the symbol of ideal attractiveness. And fashion il-lustration is about 8.5 life-size and show mus-cular slim type that is slim silhouette. 10 At the present time the ideal type is slim and tall type which is empasized healthy beauty. And fashion illustration is 12 life-size which has healthy body and skin So that is slim and long type.

• 한국패션뷰티학회지
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• 제3권2호
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• pp.55-64
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• 2005

The purpose of this study is to investigate consumers' knowledge and preference towards functional cosmetics. Through the beauty advisors' surveys, their own selling styles and consumer behaviors recognized by beauty advisors were analyzed. It was intended to help extend and strengthen the functional cosmetic market which has continued to grow rapidly since the approved goods under cosmetic law in 2001. For this study, the data was collected through questionnaires the professional consumer counselors confirmed from Korean women over the age. of twenty old living in the Seoul and Kyoungki areas. After pre-research was implemented on 45 women, 328 samples were analyzed as final samples. In addition,46 samples, which were collected through the questionnaires from beauty advisors were analyzed. Samples were analyzed by frequency, percentage, T-test, ANOVA using the SPSS program. The results of study were as follows: First consumers recognized whether functional cosmetics or not. According to the beauty advisor's surveys, consumers regard the functional cosmetic boundary as being wider than real functional cosmetic boundary according to cosmetic law. So, there is a gap between consumers' opinions and real law. Second, regarding the purchasing channels, the largest channel is the cosmetic store. As far as consumers are concerned the most important factor when buying cosmetics, is the suitability of their own skin types. The second factor is product quality and the third factor is price. Functional cosmetics non-experienced group are more concerned with price compared to experienced group. Related to purchasing products, functional cosmetics experienced group buy set products compared to non-experienced group buy one product. Third, the ultraviolet filter cosmetics portion is the largest in the functional cosmetics market the second largest portion is bleaching cosmetics and the third largest portion is the anti-senility cosmetics. However, Most preferred by consumers is the anti-senility cosmetics. Moreover, preference for ultraviolet filter cosmetics is the least. Finally, the level of satisfaction for functional cosmetics is high and dissatisfaction is low. Consumers feel that beauty advisors are simply pushing high priced products without recognizing the consumers' real needs. In conclusion, to develop the functional cosmetic market continually in the future, it needs to extend various products and advertise them until consumers are more aware.

• 대한화장품학회지
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• 제38권1호
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• pp.91-101
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• 2012

본 연구는 중앙아메리카의 폴리페놀 화합물로 이루어진 선바위고사리과에 속하는 양치식물 칼라구알라(Polipodium leucotomos)가 자외선 유해성으로부터 피부를 보호할 수 있는 항산화력과 활성 산소 유리기 농도를 알아보는데 그 목적을 두었다. 본 연구를 위하여 30대 이상 남녀 14명을 대상으로 4주 간 2개의 그룹으로 나누어 각각 칼라구알라와 위약을 섭취, 30 min 후 자외선에 노출되도록 하였다. 노출 후 3 h이 경과된 후에 각각 전완정맥에서 채혈하여 활성 산소 유리기(free oxygen radical) 농도와 총항산화능(total antioxidant capacity, TAC)을 비교 분석하여 다음과 같은 결과를 요약할 수 있었다. 첫째, 칼라구알라는 4주 후 활성 산소 유리기 농도를 유의하게 감소시켰고, 자외선 노출 30 min 후와 3 h 후의 활성 산소 유리기 농도는 위약군에 비해 유의하게 감소시키는 것으로 나타났다. 둘째, 칼라구알라는 4주 후 안정 시 총항산화능력을 유의하게 증가시키지 못하였지만, 자외선 노출 30 min 후와 3 h 후의 총항산화능력은 위약군에 비해 유의하게 감소시키는 것으로 나타났다. 사회가 급속도로 성장함에 따라 발생하는 대기오염, 각종 공해로 인하여 성층권에서 지속적으로 오존을 감소시켜 지상에 도달하는 유해 자외선량이 증가한다. 이는 활성화산소를 증가시켜 질병과 노화를 촉진시키는 요인이 된다. 기존의 반사와 산란작용으로 1차 피부를 차단하는 보호제외에도 칼라구알라와 같이 신체 내부에서 2차 차단을 할 수 있는 경구용 광항산화제의 연구가 계속적으로 이루어져야 할 것으로 사료된다.

• 문화기술의 융합
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• 제3권3호
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• pp.37-42
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• 2017

본 연구는 피부의 각질층에 분포되어 있는 유지질의 변화 상태를 조절하는 구조체계에 대해 고안한다. 피부구조에 유지질 성분이 어떻게 진행되는지 형태학으로 구성하였고, 주어진 세포사이와 세포횡단의 조건으로 기계적으로 조절되는 형태를 구성하였으며, 구조적인 기능으로 조절기능의 변화 상태를 확인하였다. 유지질 성분에서 피부의 모형을 구성하여 각층에 따른 유기질 상태의 피부 임피던스를 피부의 측정 임피던스 시스템으로 구성하여 진행하였다. 측정 임피던스는 ${\lambda}-Lip-RSC$, ${\lambda}-Lip-RSL$, ${\lambda}-Lip-CSG$, ${\lambda}-Lip-CSS$ 와 ${\lambda}-Lip-RSB$로 형성하였고, 세포사이와 세포횡단의 조건으로 변화의 차가 있고, 변환을 제어하는 전달시스템을 구성과 변환모델을 세분화하여 구축하였다. 앞으로 유지질 상태에서 피부의 기능적 효능조절이 가능한 유지질 성분의 조절시스템을 구성하여 지속적인 피부의 개선효과가 진행 될 것으로 예상된다.

• 문화기술의 융합
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• 제3권3호
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• pp.31-36
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• 2017

본 연구는 보습상태에서 피부의 각질층에 변화상태를 구조적으로 모델링한다. 피부구조에 따라 진행되는 형태는 세포사이와 세포횡단의 조건으로 조절 할 수 있도록 하였고, 구조적인 모델링으로 시스템의 변화상태를 확인하였다. 보습조건에서 크기 형태 조합의 모형을 구성하고, 결과적으로 보습상태의 피부 임피던스는 각층에 따라 피부에 측정 임피던스가 ${\xi}-R-SC-RH$, ${\xi}-R-SL-RH$, ${\xi}-R-SG-RH$, ${\xi}-R-SS-RH$ 와 ${\xi}-R-SB-RH$ 로 다른 형태로 나타났다. 보습조건에서 S-Corneum, S-Lucidum, S-Granulosum, S-Spinosum 과 S-Basale의 변화의 차가 있고, 변환을 제어하는 전달시스템을 구성과 변환모델을 세분화하여 구축하였다. 이를 통하여 보습상태에서 피부의 기능적 효능조절이 가능한 보습조절시스템이 구성되어 지속적인 피부의 개선효과가 진행 될 것으로 예상된다. 투과 조절시스템이 구성되어 지속적인 피부의 개선효과가 진행 될 것으로 예상된다.

• 복식문화연구
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• 제9권2호
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• pp.235-249
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• 2001

This study the changing aspects in accessories, skin care and hair style in 「Maeil Shinmun」 from Jan. 1, 1946 to Dec. 31, 2000, and the results are as follows. In the period of 1946 to 1959, articles were about how to select accessories and the role of skin-protection cosmetics for skin care, and the cases of people wearing color makeup in pursuit of beauty increased. The hairstyle trend began to gradually shift from long hair toward short. During the time of 1960 to 1969, how to select accessories an also how to match them with clothes were dealt with in articles, and how to massage face or use pack for healthy skin was introduce. From 1970 to 1979, as the number of working women increased, proper use of accessories according to each occasion was introduced, and, for hairstyle, the way to keep their hair healthy and shine, rather than a fashion of its style itself, was emphasized. In 1980∼1989, as casual wear became so popular worldwide and a variety of way to use shoes, mufflers, scarfs, shawls, and hats to go with it were highlighted, practical fashion got in vogue and use of accessories with which individuality can be expressed in a simple way prevailed. During the time of1990 to 2000, the trend changed to the pursuit of chic using accessories that reveal wearers'individuality, and especially came the boom of charming schools and makeup lesson for skin care. The prominent trend was that men and women of the new generation expressed their individuality by having their hair partly dyed or fully dyed in various colors and tried to resemble famous entertainers. In particular, as people get more and more interested in body shape, various ways to take care of body were introduced, such as body care products and aroma treatments.

• 한방안이비인후피부과학회지
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• 제20권2호통권33호
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• pp.10-35
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• 2007

Objectives : To investigate the effects of Ohbaesangami (OBSGM) on mucosa and skin diseases, anti-microbial and anti-inflammatory tests were performed using several in vitro test models. Results : In anti-microbial test, OBSGM showed the slight inhibitory effect against Propionibacterium acnes (P. acnes) and Staphylococcus aureus (S. aureus). In anti-oxidant test, OBSGM showed the potent radical scavenging activity. In anti-inflammatory test, OBSGM weakly inhibited the lipopolysaccharide (LPS)-induced nitric oxide(NO) release from the RAW 264.7 macrophage cells. OBSGM also inhibited the LPS-induced $interleukin-1{\beta}(IL-1{\beta})$ and cyclooxygenase-2 (COX-2) expressions. The inhibitory effects of OBSGM on macrophage activation was via the inhibition of $NF-{\kappa}B$, evidenced by transient transfection assay. Furthermore, OBSGM markedly inhibited the activation of Jun-N-terminal kinase (JNK) and p38 MAP kinase in RAW 264.7 cells. In skin wrinkle formation assay, OBSGM strongly inhibited collagnease and elastase, whose activities are tightly related with the wrinkle formation. In addition, OBSGM inhibited the activities of MMP-1, MMP-2 on the mRNA levels in RAW 264.7 cells. However, OBSGM did not show an inhibitory potential on tyrosinase activity and melanin synthesis, indicating that it could not be applicable for skin whitening. Conclusion : These results suggest that the anti-inflammatory effect of OBSGM may be due to its inhibitory potentials on the macrophage activation. And, the anti-wrinkle effects of OBSGM may be due to its inhibitory potential on the collagnease and elastase activities. Therefore, OBSGM could be applicable for the treatment of mucosa and skin diseases.