• 대한암한의학회지
• /
• 제22권1호
• /
• pp.13-22
• /
• 2017

Objective: The purpose of this study is to report the effect of Nobongsangki-Jeong on skin rash caused by Olmutinib. Methods: A female Non-Small cell lung carcinoma patient (Adenocarcinoma, Stage IV, Epidermal Growth Factor Receptor positive) suffered from skin rash due to the side effect of Olmutinib administration. She was treated with Nobongsangki-Jeong for the symptom management for 14 days. The clinical outcomes were measured by numeric rating scale (NRS) and National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE) version 4.03. Results: After treatment, skin rash was improved from NRS 5 to 1. Pruritus and pain of skin were improved from NCI-CTCAE grade 2 to 1. Conclusion: This case study suggests that Nobongsangki-Jeong may have the efficacy for the treatment of skin rash caused by Olmutinib.

• Child Health Nursing Research
• /
• 제5권3호
• /
• pp.241-249
• /
• 1999

Diaper dermatitis, or commonly called 'diaper rash', is among the most prevalent cutaneous disorders of infancy and early childhood and important issue in nursing. The term itself is not diagnostic since it encompasses a variety of acute inflammatory reactions which are best regarded as a family of disorders arising from a combination of factors specifically attributable to the use of diapers Intensive study of the rash Process has shown that skin wetness and fecal enzyme activity are damaging to skin and lead to the development of diaper rash. This suggests that it is important to keep urine away from babies' skin, so that the skin remains as dry as Possible and maintains its barrier function abilities. Controlling the urine will also minimize the mixing of urine and feces within the diaper. which helps prevent the increased activity of enzymes that attack the skin and cause irritation. Therefore, a diaper that keeps the skin drier and limits the mixing of urine and feces will help Prevent the conditions that lead to diaper rash. Since their introduction about 35 years ago, disposable baby diapers have undergone many design and performance changes. In Particular. the Performance of diapers was advanced by the introduction of absorbent gel materials (AGMs) to Provide advantages in skin care. dryness, and leakage Protection Especially, important was the introduction of AGM which increased the absorbent capacity of the diaper several fold and Yielded marked reductions in the degree of skin hydration occurring under the diaper Studies show not only drier skin but more stable skin pH and less dermatitis with AGM diapers than with home-laundered cloth diapers or single-use diapers without AGM Minimizing diaper area skin wetness is important for managing and Preventing diaper rash. To minimize wetness, parents should use super absorbent diapers.

• Journal of Korean Neurosurgical Society
• /
• 제29권12호
• /
• pp.1673-1676
• /
• 2000

Anticonvulsant hypersensitivity syndrome is a rare but fatal complication. It manifests as fever, skin rash, lymphadenopathy, and hepatitis. Phenytoin, phenobarbital, and carbamazepine are the most frequently involved drugs. We here report a case of phenytoin-induced anticonvulsant hypersensitivity syndrome. A 37-year-old woman presented with fever and generalized skin rash, 3 weeks following commencement of phenytoin 400mg daily for treatment of seizure after superficial temporal artery-middle cerebral artery(STA-MCA) anastomosis for moyamoya disease. Her temperature was $39.3^{\circ}C$ and her face was edematous. Laboratory findings showed elevated hepatic enzymes and eosinophilia. Blood and urine culture were all negative. Initially, prednisolone was commenced at 30 mg daily. But fever and skin rash did not improved and hepatic function was more aggravated. After increasing dose of steroid(methylprednisolone 125mg/day), fever and skin rash disappeared and hepatic enzymes returned to normal range.

• 대한한의학회지
• /
• 제44권3호
• /
• pp.117-125
• /
• 2023

Objectives: This study is to report a case of prurigo nodularis with skin rash that occurred after COVID-19 vaccination improved by Korean medicine treatment. Methods: The patient visited our hospital complaining of prurigo nodularis and skin rashes which occurred in various parts of the body (Total score 17). The patient complained of sleep disturbance (NRS 9) due to nighttime pruritus (NRS 7). Based on the patient's symptoms, herbal medicine Soshiho-tang and acupuncture on the left Triple Energizer Hangyeok was prescribed. Results: Most of the skin symptoms improved significantly leaving only scars, minor scratches and pigmentation (Total score 17 → 6). The patient's sleep condition improved (NRS 7 → 1) as the pruritus decreased from NRS 9 to 2. Conclusions: This study is significant in that the patient with prurigo nodularis accompanied by skin rash effectively improved by the Korean Medicine treatment.

• 한국환경보건학회지
• /
• 제30권2호
• /
• pp.65-70
• /
• 2004

Hair is based upon the skin which enroll the body of high living animals and have multiple membrane structure. This study were used rats and carried out to find out the effects of commercial permanent wave products to skin which are composed of thioglycolic acid and bases. Results were as follows. Permanent wave penetrated to 3 hours later with steady state in skins and was not significant changeable after 20hr later. In case of neutralizer with thioglycolic acid lag time and permeability coefficient in healthy skin were 3.38hr and 0.96$\mu\textrm{g}$/$\textrm{cm}^2$/hr, in old skin were 3.14hr and 0.l28$\mu\textrm{g}$/$\textrm{cm}^2$/hr, and in wounded skin were 3.08hr and 0.157$\mu\textrm{g}$/$\textrm{cm}^2$/hr. In conclusion, lag time and permeability coefficient in old skin and wounded skin were faster than healthy skin. In vivo which was studied by general time and method of permanent wave. We found out that fine rinkle and rash of skin were changeable in the case of treating with permanent wave drugs than normal skin. Also, permanent wave drugs could induced rash and eruption at the skin by the naked eye.

• Journal of Yeungnam Medical Science
• /
• 제33권1호
• /
• pp.1-7
• /
• 2016

The two distinctive clinical features of varicella-zoster virus (VZV) are varicella (chickenpox) by primary infection and zoster (singles) by the reactivation of latent infection. In addition to the two typical clinical symptoms mentioned above, diverse clinical manifestations have been reported as a result of VZV reactivation, including chronic radicular pain without rash, visual loss, facial palsy, dysphagia, sore throat, odynophagia, otalgia, hearing loss, dizziness, headache, hemiplegia, etc. Most of these symptoms are derived from neuropathy and vasculopathy of affected nerves and arteries. Diagnosis of VZV disease can be difficult if there is no appearance of a skin rash during development of atypical symptoms. In addition to natural infection, vaccination and anti-viral agent treatment have influenced the changes of epidemics and clinical presentations of varicella and zoster. In this article, diverse clinical manifestations caused by VZV reactivation, particular without skin rash, are reviewed.

• 대한의료기공학회지
• /
• 제11권1호
• /
• pp.80-116
• /
• 2009

It studies into viewpoints of 7 doctors of Wenbing studies on macula. The results concerning characteristics, remedy and prevention of macula are as follows; Macule does not protrude on the surface of skin and does not have any color change for external stimulus, but rash out on the surface and becomes white when pushed. It becomes macule when the blood leaks beneath skin as stomach-heat of yangming enters into blood system and damages it. On the other hand, when heat enters lung meridian, penetrates beneath the skin and congeals inside the vessel, it becomes rash. When you combine symptoms of body and pulse with numbers, color, shape and distribution status of macula, you can diagnose the depth of rash, seriousness, the possibility of treatment and prognosis of macula. The remedy for macule consists of cooling heat of yaming, removing heat from the blood and relieving feverish rash, and the one for rash consists of facilitating meridian with aroma, expelling pathogenic factors from muscles with drugs of pungent flavor and cool nature and clearing away heat from the blood systems. It relieves the inhibited functional activities of lung-Ki, and helps extermination of rash as well as clearing heat of the vessel. Also, it is the most important to preserve resin of stomach for every treatment. It is good to avoid expelling pathogenic factors with drugs of pungent flavor and warm nature, raising drugs and invigorating drugs during treating macula. Moreover, the patients should not over dose cold-natured drugs and purgative therapy. There are common clinical symptoms of macula in advance, so right recognition of symptoms can contribute to prevention of macula.

• Clinical and Experimental Pediatrics
• /
• 제54권12호
• /
• pp.512-514
• /
• 2011

Congenital syphilis is one of the most well-known congenital infections, yet it remains a worldwide public health problem. Congenital syphilis can involve any organ system and present with various symptoms. However, early diagnosis of congenital syphilis is difficult because more than half of the affected infants are asymptomatic, and the signs in symptomatic infants may be subtle and nonspecific. Here, we report a case of congenital syphilis with only a skin rash, which led to a delay in diagnosis. This case indicates that congenital syphilis should be considered throughout early childhood.

• 한국의상디자인학회지
• /
• 제24권1호
• /
• pp.45-57
• /
• 2022

A rash guard, also known as rash vest or rashie, is functional sportswear that protects the wearer's skin from various dangers during outdoor sports activities. It is durable and comfortable since it is designed considering muscle movement. In modern society, more and more people enjoy leisure activities due to an increase in income level and increased leisure hours. Water leisure activities are increasingly enjoyed in the summer. As the way people think of leisure evolves, people are more inclined toward dynamic leisure sports rather than static facility tourism. Therefore, more research on rash guards is required. By identifying and analyzing the design preferences and purchase behaviors of young adults on rash guards, this study aims to provide basic data on the actual sportswear behaviors concerning those who are most active in water sports, people in their 20s and 30s. Furthermore, the study aims to contribute to a healthy exercise lifestyle for women who enjoy water sports and the growth of the water sportswear market. In the study, a survey was conducted using a questionnaire to investigate the wearing behaviors and purchase preferences as well as the wearing satisfaction on rash guards. For the study, 200 copies of the questionnaire were distributed and collected to be used as analysis data. The questionnaire consisted of 36 questions, 6 about demographic characteristics, 11 about purchase preferences, and 19 about wearing satisfaction. The collected data was analyzed using the statistical program SPSS 8.0. The study results can be used as basic data to investigate the design preferences and wearing behaviors of rash guards of women in their 20s and 30s. The results found numerous complaints on comfortableness and durability, which suggests more concern and improvements are necessary in those areas when designing patterns for rash guards.

• 한국응용과학기술학회지
• /
• 제19권1호
• /
• pp.19-24
• /
• 2002

It is a great role that the character of man or woman could be distinguished by hair on the aspect of ornament. Hair will be support of beautifulness of human being in various permanent wave by many kinds of its drugs. Hair is based upon the skin which enroll the body of high living animals and have multiple membrane structure. This study used rat and the effects of commercial permanent wave products to skin which are composed with thioglycolic acid and bases. Results are as follows. Permanent wave penetrated to 4 hours later with steady state in skins and was not significant changeable after 20hr later. In case of neutralizer with thioglycolic acid lag time and permeability coefficient in healthy skin is 3.38hr and $0.094^{\mu}g/cm^{2}$ ${\cdot}$ hr, it old skin is 3.48hr and 0.129$^{\mu}g/cm^{2}$ ${\cdot}$ hr, and it wounded skin is 4.72hr and $0.158^{\mu}g/cm^{2}$ ${\cdot}$ hr. In conclusion, lag time and permeability coefficient in old skin and wounded skin are faster than healthy skin. In vivo which was studied by general time and method of permanent wave. We notified that fine rinkle and rash of skin were changeable in the case of treating with permanent wave drugs than normal skin. We can see even rash and eruption by the naked eye.