• Title/Summary/Keyword: Skin Inflammation

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A Study on Peanut Spouts Extract as the Anti-oxidant Activity and the Skin Whitening Cosmetic Ingredients (항산화 및 미백화장품 원료로서의 땅콩새싹 추출물에 관한 연구)

  • Yoon, Mi Yun
    • KSBB Journal
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    • v.31 no.1
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    • pp.14-19
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    • 2016
  • To investigate the effect of peanut sprout extract on skin care, we measured anti-oxidant activity and whitening action. As a result of measuring DPPH radical scavenging activity to examine independent anti-oxidation of peanut sprout extract, there was strongly scavenging activity. Fluorescent material DCF-DA was used to measure hydrogen peroxide created in RAW 264.7 cells, and all concentration dependently decreased ROS production. As a result of measuring nitric oxide to examine anti-inflammation of peanut sprout extract, there was strongly inhibited nitric oxide production in RAW 264.7 cells. Tyrosinase activation was found to inhibited dose-dependant. Melanin production was also prevented dose-dependant. Therefore, it is expected to be used effectively in development of functional cosmetic materials.

A Case of improvement in a patient with dermatitis by using Ortho-Cellular Nutrition Therapy (OCNT) (세포교정영양요법(OCNT)을 이용한 피부염증 환자 개선 사례)

  • Yeon Choi
    • CELLMED
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    • v.13 no.13
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    • pp.49.1-49.6
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    • 2023
  • Objective: A Case report on the improvement of dermatitis through implementation of OCNT. Methods: OCNT was implemented for 3 months for a Korean man in his 70's with dermatitis with unknown cause since 2015. Results: Following the implementation of OCNT, fever that accompanied dermatitis subsided, occurrence of itchiness and abscess decreased, and the stratum corneum of the palm although displayed improvement of being thinned. As the result of visual follow-up observation upon discontinuation of OCNT, damaged skin due to inflammation was restored to the level of normal skin. Conclusion: OCNT can provide assistance to those experiencing inconvenience due to dermatitis.

CELECOXIB INHIBITS PHORBOL ESTER-INDUCED EXPRESSION OF CYCLOOXYGENASE-2 AND ACTIVATION OF ERKl/2 IN MOUSE SKIN IN VIVO

  • Chun, Kyung-Soo;Surh, Young-Joon
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.137-138
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    • 2001
  • There has been accumulating evidence for the association of inflammatory tissue damage with the process of cancer development. Cyclooxygenase (COX), an important enzyme involved in mediating the inflammation, catalyzes the formation of prostaglandins (PGs) from arachidonic acid. There are two isoforms of COX, designated as COX-l and COX-2. COX-l is a housekeeping enzyme which is constitutively expressed and is thought to be involved in maintaining physiological functions.(omitted)

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Application of Rats According to Molecular Weight of Chitosan (키토산의 분자량에 따른 랫드에서의 적용)

  • Jung, Duck-Chae;Lee, Ki-Chang;Yoon, Cheol-Hun;Kim, Pan-Gyi;Shin, Dong-Hwan
    • Journal of Environmental Health Sciences
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    • v.25 no.3
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    • pp.58-63
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    • 1999
  • Biodegradable films were prepared by solution blend method in the weight ratio of chitosan for the purpose of useful biomaterials. The possibility of biomaterials prepared from natural polymer as a skin substitute was evaluated by measuring biocompatibility. These films were inserts in the back of rat and their biodegradability was investigated by the film weight and hematology as a function of time for the biotransformation. The result of rat test showed that medium, high viscosity chitosan induced some suspects of inbiocompatibility in the tissue by goreign body reaction 48 and 72 hours after implantation. Also, we prepared the official burn ointment which is made by low viscosity chitosan. This burn ointment was covered on the skin wound of artificial burn and their effect of healing was investigated by the evaluation of the naked eye and hematological change as a function of time. The result of rats test showed that burn ointments made from chitosan was effective reductio of inflammation than negative group.

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Clinic Study of Gami-Yunbueum Efficacy on the Psoriasis (건선에 대한 가미윤부음의 임상연구)

  • Kim Byoung Soo;Lee Sangkeun;Lee Jeung Haem;Lim Jong Soon;Kang Jung-Soo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.6
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    • pp.1543-1546
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    • 2003
  • Psoriasis is a common inflammatory disease of the skin marked by excessive scaling associated with inflammation, affecting 1-2% of the population. Although their etiologies remain unknown, the finding of CD4+ and CD8+ lymphocytes at sites of psoriasis has led many reports to hypothesize that psoriasis is a T lymphocyte-mediated disease directed against unknown autoantigens. The oriental medicine understands the cause of psoriasis as low humidity of skin tissues and functional deteriorations of the liver and lung. Gami-Yunbueum (GY) is a mixture of two previous prescription, which were used to the protection of liver and lung. We had prescribed the GY to the three psoriasis patients for 11 weeks and examined the effectiveness of the GY by PASI (Psoriasis Area and Severity Index) score. In our experiment, GY improved the symptoms of psoriasis in all cases. These results indicated that GY can apply to the treatment of psoriasis. Furthermore, the process for treatment of psoriasis is possible to provide humidity to skin and control the functions of liver and lung.

Biodegradation and Preparation of Biodegradable Film by using Natural Gums (천연 Gum류를 이용한 생분해성 필름의 제조와 생체분해)

  • Hwang, Sung-Kwy;Kim, Pan-Gyi;Hwang, Seong-Hee
    • Journal of the Korean Applied Science and Technology
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    • v.15 no.4
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    • pp.71-78
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    • 1998
  • Gum is known as natural polymer. Biodegradable films were prepared by solution blend method in the weight ratio of natural gums(Xanthan, Locust bean, Guar) for the purpose of useful bioimplants. The possibility of bioimplants, which prepared from natural gums as a skin substitute was evaluated by measuring biodegradability. This biodegradable films were inserted in the back of rats and their of biodegradability were investigated by hematological change evaluation as a function of time to the biotransformation. Rats implantation test results showed that Guar induced increments of monocyte and basophil after 48 hours of implantation. And Locust bean showed increase of monocyte and neutrophile counts after 48 hours of implantation. And Xanthan induced decrease of monocyte and neutrophile at 24 hours after implantation. Guar and Locust showed high hemoglobin contents and hematocrit after 48 hours of implantation. Guar and Locust induced some suspects of incompatibility in the tissue after 48 hours, but three were little effects to the skin inflammation at 24 hours. These values of biodegradable films, which prepared from prepared from natural gums measured in this were some satisfiable results at short period with those of ideal skin bioimplants.