• 한국대기환경학회지
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• 제14권6호
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• pp.631-642
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• 1998

Fall-out particles were collected by the modified British deposit gauges at 35 sampling sites in Suwon area from January to November, 1996. Twenty chemical species (Al. Ba, Cd, Cr, K, Pb, Sb, Zn, Cu, Fe, Ni, V, F-, Cl-, NO3-, 5042-, Na+, NH4+, Mg2+, and Ca2+) were analyzed by AAS and If. The purposes of this study were to estimate qualitatively various emission sources of the fell-out particle by applying multivariate statistical techniques such as factor analysis, multiple regression analysis, and discriminant analysis. During the study, outlier sites were determined by a z-score method. Cl-, Na+, Mg2+, and SO42- were highly correlated due to their common marine related source. Wind speed was the most influential factor for the deposition fluxes of the particle itself and all the chemical species as well. When applying the factor analysis, 8 source patterns were qualitatively obtained, such as marine source, soil source, oil burning source, Cr related source, tire source, Cd related source, agriculture source, and F- related source. As a result of the multiple regression analysis, we could suggest that some chemical compounds may possibly exist in the form of CaSO4, NaN03, NaCl, MgC12, (NH4)2SO4, NaF, and CaCl2 in the fall-out particles. Finally, spatial and seasonal classification study performed by a discriminant analysis showed th.at SO42-, Ca2+, Cl-, and Fe were dominant in the group of spatial pattern; however, SO42-, Cl-, Al, and V were in the group of seasonal pattern.

• Journal of Microbiology and Biotechnology
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• 제24권9호
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• pp.1189-1195
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• 2014

A strain-specific identification method is required to secure Chlorella strains with useful genetic traits, such as a fast growth rate or high lipid productivity, for application in biofuels, functional foods, and pharmaceuticals. Microsatellite markers based on simple sequence repeats can be a useful tool for this purpose. Therefore, this study developed five novel microsatellite markers (mChl-001, mChl-002, mChl-005, mChl-011, and mChl-012) using specific loci along the chloroplast genome of Chlorella vulgaris. The microsatellite markers were characterized based on their allelic diversities among nine strains of C. vulgaris with the same 18S rRNA sequence similarity. Each microsatellite marker exhibited 2~5 polymorphic allele types, and their combinations allowed discrimination between seven of the C. vulgaris strains. The two remaining strains were distinguished using one specific interspace region between the mChl-001 and mChl-005 loci, which was composed of about 27 single nucleotide polymorphisms, 13~15 specific sequence sites, and (T)n repeat sites. Thus, the polymorphic combination of the five microsatellite markers and one specific locus facilitated a clear distinction of C. vulgaris at the strain level, suggesting that the proposed microsatellite marker system can be useful for the accurate identification and classification of C. vulgaris.

• 정보과학회 컴퓨팅의 실제 논문지
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• 제22권6호
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• pp.290-295
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• 2016

최근 사용자들이 협동적으로 이미지 주석인 태그를 만들고 활용하는 폭소노미 기반의 이미지 공유 사이트들이 많은 인기를 얻고 있다. 이러한 사이트는 사용자 질의에 대해 단순한 텍스트 매칭 기반의 검색을 수행하고 매칭되는 결과 이미지들을 포토 스트림 형태로 나열하여 보여 준다. 하지만 이러한 태그들은 매우 개인적이고 주관적이며, 이미지 역시 카테고리로 분류되어 있지 않기 때문에 검색의 정확도나 사용자 만족도가 떨어진다는 문제점이 있다. 본 연구에서는 태그를 기반으로 하는 이미지 검색에서 검색의 정확도를 높일 수 있는 폭소노미 이미지의 카테고리화 기법을 제안하고, 폭소노미 환경에서 생성된 태그와 이미지 정보를 모두 이용하며 의미적으로 유사한 이미지들끼리 분류된 검색 결과를 생성한다. 제안하는 기법의 성능 평가를 위해 폭소노미 이미지를 수집하고 텍스트, 이미지 특성에 따른 카테고리 분류를 수행하여 기존 검색 기법과 이미지 검색의 정확도를 비교한다.

• Journal of Korean Neurosurgical Society
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• 제41권5호
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• pp.283-290
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• 2007

Objective : This study was designed to analyze seizure outcome and to investigate the prognostic factors for predicting seizure outcome according to the preoperative evaluations, surgical procedures, topectomy sites and histopathological findings in patients with extratemporal lobe epilepsy [ETLE]. Methods : This study comprised 63 patients with ETLE who underwent surgery. Preoperative evaluations included semiologic analysis, chronic video-EEG monitoring, and neuroimaging studies. Surgical procedures consisted of topectomy in 51 patients, corpus callosotomy in 9, functional hemispherectomy in 2, and vagus nerve stimulation [VNS] in 1. Histopathological findings were reviewed. Postoperative seizure outcomes were assessed by Engel's classification at the average follow up period of 66.8 months. Chi-square test was used for statistics. Results : Total postoperative seizure outcomes were class I in 51 [80%] patients, class II in 6 [10%], class III in 6 [10%]. Patients with structural abnormalities on neuroimaging study showed class I in 49 [88%] patients [p<0.05]. Patients with focal and regional ictal EEG onset revealed class I in 47 [90%] patients [p<0.05]. Semiologic findings, surgical procedures, topectomy sites and histopathological findings did not show statistical correlation with seizure outcome [p<0.05]. Conclusion : A good seizure outcome was obtained in patients with ETLE. The factors for favorable seizure outcome are related to the presence of structural abnormalities on neuroimaging study, and focal and regional ictal EEG onset.

• 한국환경과학회지
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• 제16권12호
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• pp.1451-1462
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• 2007

Heavy metal concentrations in the soil were investigated for the abandoned Samkwang metal mine, Cheongyang-Gun, Chungnam Province, Korea. The concentrations of heavy metal(As, Cd, Cu, Ni, Pb, Zn) were determined in mine soils collected at the abandoned mine sites to obtain a general classification and specification of the pollution in this highly polluted region. The results estimated with the normal test and basis statistic on the central tendency and variation showed that the distribution of heavy metal concentration had significantly different at the range of all locations. The range of spatial distribution on the relationship of heavy metal concentration and pH was $4.8{\sim}8.8$ and heavy metal concentration on the type of land use was highest in forest land, and also Ni and Zn in farm and rice field showed the high concentration. The distribution of heavy metal concentration on the depth of a soil showed that the metal concentrations in subsoil were higher than of those in surface soil, while the concentration of Cu and Ni had no significant difference on the depth of soil. Results from the correlation analysis using the data except the extreme and unusual data revel that Zn-Cd(r=0.867), Zn-As(r=0.797), Zn-Pb(r=0.764), Cu-Cd(r=0.673), Cu-As(r=0.614) and Zn-Ni(r=0.605) were the most important parameters in assessing variations of heavy metal in soil. To discriminate pattern differences and similarities among samples, principal factor analysis(PFA) and cluster analysis(CF) were performed using a correlation matrix. This study suggests that PFA and CF techniques are useful tools for identification of important heavy metal and parameters. This study presents the necessity and usefulness of multivariate statistical assessment of complex databases in order to get better information about the quality of soil and gives the basis information to clean up the abandoned mine sites.

• 약학회지
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• 제36권3호
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• pp.220-229
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• 1992

The muscarinic acetylcholine receptors of the dog unpregant uterus were characterized using $[^3H]quinuclidinyl$ benzilate(QNB) as a radioligand and the binding of muscarinic receptor agonists and antagonists in the uterus was compared to that in the urinary bladder which contains almost exclusively the M2 receptors in order to determine the receptor subtypes in the uterus. $[^3H]QNB$ binding to uterus and bladder was rapid, saturable and reversible. Scatchard analysis of the saturation data gave linear plots and the Hill coefficients were close to unit, which indicated that each preparation contained a single population of specific binding sites for $[^3H]QNB$. The KD values(120 pM) for QNB were almost identical in both organs, whereas the $B_{max}$ value of 256 fmol/mg protein in the uterus was significantly different from that of 563 fmol/mg protein in the bladder. Muscarinic agonists and antagonists inhibited in a competitive manner the $[^3H]QNB$ binding to the same extent in both organs. The competition binding studies using antagonists(atropine and pirenzepine) exhibited a single binding site and this site had a low affinity for pirenzepine with the Ki value of about 330 nM. However, high and low affinity binding sites were observed with carbachol, methacholine and oxotremorine. These binding studies with agonists and antagonists did not show any differences in drug affinities between uterus and bladder. These results indicate that the muscarinic receptors in the uterus are M2 receptors which have a low affinity for pirenzepine.

• 한국환경보건학회지
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• 제32권5호
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• pp.522-531
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• 2006

This study has been conducted to evaluate the influence of ambient heavy metals to the air quality and to find their sources in Ulsan. Korea. The distribution characteristics of ambient heavy metals with wind direction were investigated by using pollution-rose diagram. Carcinogenic risk for five trace heavy metals (Pb. Cd, Cr, Mn, and Ni), which are classified to carcinogenic material by US EPA, are assessed according to the classification system of USEPA and WHO. According to pollution-rose calculation on pollutants sources, Pb and Cu in Deoksin, which is an adjacent to Onsan industrial complexes, were $0.1058\;and\;0.3242{\mu}g/m^3$. These concentration levels are the highest at all sampling sites. From this result we could confirm that it was affected by Onsan industrial complex that is located northeast of Deoksin.,And the maximum concentration of Cd, Cr, and Ni were $0.0306,\;0.0102,\;and\;0.0146\;{\mu}g/m^{3} in Yeocheon respectively. Because Yeocheon is in the Mipo industrial complexes, which have many combustors, incinerators, and manufacturing facilities compared to other regions. In carcinogenic risk assessment, Pb, Ni, and Mn concentration level at six sampling sites were lower than the risk level guideline values ($10^{-5}$) of WHO. However, $Cr^{6+}$ and Cd concentration in Yeocheon were 60% and 205% higher than the guideline values of WHO. Therefore it is very important that the emission from industrial complexes were carefully managed and controlled to improve air quality in residential area.

• 한국지반공학회논문집
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• 제34권9호
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• pp.43-49
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• 2018

감쇠식을 이용한 지진재해평가는 다양한 사회기반시설을 대상으로 한 프로젝트에 널리 수행된다. 이에 따라, 다양한 지반 조건에서의 최대지반가속도 예측을 위한 수많은 감쇠식과 관련 연구들이 수십 년에 걸쳐 이루어졌다. 하지만 기존에 제시된 대부분의 감쇠식들은 일반적으로 토층 상부 30m에 대한 평균 전단파 속도를 지반 분류의 기준으로 적용하여 다양한 지반 조건에서의 지진 규모나 최대지반가속도를 예측할 수 있도록 제시되어 터널이나 원자력 발전소와 같이 기반암을 기초로 하여 건설되는 특수한 유형의 사회기반시설물에 적용하기에는 불확실성을 지니고 있었다. 본 연구에서는 일본에서 측정된 데이터를 기반으로 암반 조건에서의 최대지반가속도 예측이 가능한 개선된 상관관계를 제시하였으며, 산출된 결과를 기존에 제시된 감쇠식을 통해 계산된 결과와 비교하였다. 분석결과, 기존에 제시된 감쇠식들을 통해 최대지반가속도를 예측할 경우, 200km 미만의 거리 내에 위치한 암반지역에서의 최대지반가속도를 상대적으로 과소 예측 하는 것으로 나타났다.

• 한국정보과학회논문지:소프트웨어및응용
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• 제32권5호
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• pp.378-384
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• 2005

본 논문에서는 기존의 스팸 메일 필터링 시스템의 성능을 향상시키기 위한 새로운 필터링 방법을 설명한다. 대부분의 스팸 필터링 시스템은 메일의 제목이나 혹은 그 문서 안에서 발견되는 단어들의 분포를 조사하여 이루어진다. 한편, 최근의 스팸 발송자들은 메일 서비스 업체가 제공하는 웹메일 계정을 이용하여 스팸을 발송하기 시작하였다 이렇게 웹메일을 통해 발송되는 스팸 메일의 특징을 보면, 그 메일 계정이 자동으로 생성되기 때문에 일반 사용자의 메일 계정과 많은 차이를 보인다. 본 연구에서는 이러한 점에 착안하여, 발송자의 메일 계정이 자동 생성된 메일 계정인지를 예측하고 이를 통해 스팸을 필터링하고자 한다. 메일 계정을 분류하기 위해서는 패턴 인식 문제에서 사용되어 온 결정 트리를 이용하였으며, 메일 서비스 업체로부터 수집된 약 215 만개의 메일 계정에 대해 실험하였다. 실험 결과, $96.3\%$의 정확률을 나타내었으며, 기존 시스템과 연동하여 새로운 형태의 스팸을 필터링할 수 있었다.

• Radiation Oncology Journal
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• 제11권1호
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• pp.83-90
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• 1993

During the period from January, 1975, to June, 1989, one hundred patients with histopathologically proven polymorphic reticulosis in the upper respiratory tract were treated with radiation therapy and the analysis of treatmemt results was undertaken. One hundred patients (69 males, 31 females) with a mean age of 46 years (range 12-79 years) were presented. Nasal cavity was the most frequent site of involvement ($56{\%}$), and 44 cases had multifocal sites of involvement. The incidence of cervical lymph node metastasis at initial diagnosis was $24{\%}$. Staging was determined by Ann-Arbor classification, retrospectively. The number of patients of stage IE, IIE, IIIE and IVE were 35, 60, 1, and 4, respectively. The overall 5 year actuarial survival rates were $38.4{\%}$. The difference in 5 year survival rates between patients with stage IE and IIE, with solitary and multiple, with CR and PR after irradiation were significant statistically. For the analysis of failure patterns, failure sites include the following: local failure alone (30/55=$54.6{\%}$), systemic failure alone (9/55=$16.4{\%}$), both local and systemic failure (16/55=$29.0{\%}$). Retrograde slide review was available in 29 cases of PMR with respect to histopathologic bases, and immunohistochemical studies were performed using MT1 and DACO-UCHL-1 as T-cell markers, MB2 as a B-cell marker and alpha-1-antichymotrypsin as a histiocytic markers. All that 29 cases showed characteristic histologic features similar to those of peripheral T-cell lymphoma and showed positive reactio to the T-cell marker. These findings suggest strongly that quite a significant portion of PMR may be in fact T-cell lymphoma.