• 한국환경보건학회지
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• 제44권2호
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• pp.124-132
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• 2018

Objectives: All enterprises intending to install and operate hazardous chemical handling facilities should prepare an off-site risk assessment (ORA) report that evaluates the impact of potential chemical accidents on the surrounding environment and population. This study was conducted to introduce the process of development and the functioning of the Korea Off-site Risk Assessment support tool (KORA) developed by the National Institute of Chemical Safety and to suggest manners to increase its utilization. Additionally, this article provided an overview of KORA. Methods: In order to identify problems with and refinements for KORA, the required items for each phase of KORA were derived by analyzing the Chemical Control Act and related administrative regulations. Results: The functions of KORA made receptor-considered assessment of chemical accidents possible, but several limitations were found in particular phases, such as the analysis of impact range, consideration of sensitive receptors, and assessment of environmental receptors. Conclusion: In this study, we suggested manners to increase the utilization of KORA. It is anticipated that the further research suggested in the study could contribute to the stabilization of the KORA system.

• 생명과학회지
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• 제22권9호
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• pp.1201-1206
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• 2012

Crlz1 유전자는 B 세포 분화 과정 중 pre-B 세포 분화 단계에서 특이적으로 발현됨이 밝혀져 있다. Crlz1 유전자의 발현과 연관되는 3개의 DNase I hypersensitive site (HSS8, 9, 10)가 Crlz1 유전자의 전사 시작점으로부터 바로 위쪽의 chromatin 상에서 발견되었고, 그 중에서 HSS9/10은 Crlz1 promoter 지역에 해당하며 매우 높은 전사 활성을 가지는 것으로 이미 보고 되었다. 본 연구에서는 앞의 연구에서 더 나아가 HSS8이 Crlz1 promoter의 전사활성을 약 2 배 증가시키는 enhancer의 역할을 하고 있는 현상을 밝혔으며, 또한 HSS8의 위치가 Crlz1 유전자의 전사 시작점을 기준으로 하였을 때 -1055와 -1159 사이, 즉 104 bp 길이의 chromatin DNA 상에 존재하며, 이러한 HSS8의 위치는 luciferase reporter의 활성 측정으로 비교 분석되어진 deletion construct들의 전사 활성에 대한 결과와도 잘 부합되었다.

• Journal of Gastric Cancer
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• 제7권3호
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• pp.174-179
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• 2007

진단의 발달과 치료의 발전으로 위암의 치료 성적은 괄목한 성장이 이루어졌으나 근치적 위전절제술 후 암의 발생, 즉 문합부 재발암과 전이 그리고 이시성암이 발생되었을때 외과적 치료에 대한 보고와 결과는 많지 않으며, 특히 문합부에만 국소적으로 발생된 암은 흔치 않다. 근치적 위전절제술 후 문합부에만 국소적으로 발생된 암에 대하여 적극적인 수술을 함으로써 생존이 연장되었다는 보고가 있다. 연구자들은 위선암으로 근치적 위전절제술 후 발생한 문합부 국소재발 1예, 이시성 편평상피암 1예, 림프종 1예에 대하여 원격전이가 없음을 확인한 후 수술을 시행하여 모두 좋은 결과를 얻어 이에 문헌 고찰과 함께 보고하는 바이다.

• Archives of Plastic Surgery
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• 제36권5호
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• pp.571-577
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• 2009

Purpose: The Provision of thin and pliable tissue and the adequate coverage of tendon - gliding surface is necessary for a soft tissue defect of the hand with exposure of bone, tendon and muscle. This report will discuss our experience with anterolateral thigh fascial free flap for the reconstruction of the soft tissue defect of the hand. Methods: Between February 2004 and August 2008, seven patients with full - thickness soft tissue defects of the hand were reconstructed by means of a composite anterolateral thigh fascial free flap. There were soft tissue defects associated with trauma (n=5), scar contracture (n=1) and necrosis due to ischemia (n=1). Flaps were harvested from the anterolateral thigh as adipofascial flaps with only a small sheet of fascia and fatty tissue above it. The fascia and the skin of the donor site was closed directly and delayed split - thickness skin graft was performed. Result: All flaps survived completely. The size of the transferred flap ranged from $2{\times}4cm$ to $5{\times}8cm$. Thin flap coverage was possible without secondary debulking operations. It left minimal donor site morbidity with a linear scar. In one case, the thigh muscle herniation in the donor site was developed. Conclusion: The anterolateral thigh fascial free flap provided thin and pliable tissue which can establish a tendon - gliding mechanism, minimal bulk, minimal donor site morbidity. The disadvantages of this technique were the need for a skin graft and the muscle herniation of donor site.

• 대한암한의학회지
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• 제28권1호
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• pp.1-9
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• 2023

Objectives: To demonstrate an improvement of neuropathic pain after surgical site infection in a patient with anorectal cancer by administration of Soshihotang (SSHT). Methods: A 65-year-old female patient diagnosed with anorectal cancer was administered SSHT to relieve her neuropathic pain induced by surgical site infection. SSHT was administered from 4/22 to 5/2. Clinical outcomes were assessed using a numeric rating scale (NRS), and opioids administered to relieve her pain was calculated. Results: During 10 days of treatment, the NRS scale of neuropathic pain was improved and the dosage of opioids administered reduced to less than half. Conclusions: This case suggests that SSHT could be effective for the management of neuropathic pain induced by surgical site infection.

• Radiation Oncology Journal
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• 제32권2호
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• pp.95-98
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• 2014

Extramammary Paget disease (EMPD) is a rare disease, especially in Asian populations. Surgical resection is considered the primary treatment option. Recently, radiotherapy has been suggested as an EMPD treatment, either as an alternative to surgical resection or in combination with surgical resection. This report reviewed a patient with EMPD who was treated with wide excision of the EMPD site followed by radiotherapy for remaining gross lymph node metastases. The aim of this report was to determine the optimal treatment for advanced EMPD.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제33권5호
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• pp.425-429
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• 2011

Bone grafts are becoming increasingly common in oral and maxillofacial surgery to improve bone healing procedures. Bovine bone as a xenograft is a representative osteoconductor and space filler; however, sometimes complications, such as infection and wound dehiscence are encountered with its use. We report the result of an eight-year follow-up of a xenograft case and processing methods of inorganic bovine bone along with a review of the literature. Xenograft ($LUBBOC^{(R)}$) was used in a cyst enucleation site of the maxilla, as a bone substitute and space filler. Inflammation and infection were defined several times as lack of osseous contact between the graft and host bone, caused by remodeling failure over an eight-year period. Pathologic findings of the xenograft revealed dead bony trabeculae with inflamed fibrous tissue and actinomycosis.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2015년도 추계 학술논문 발표대회
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• pp.172-173
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• 2015

Construction project involves numerous repetitive operations. Especially in high-rise and apartment houses projects, the amount of repetitive operations increase and a preceding operations delay causes serious damage to the total duration of the project. This study deducts work delay factors by site engineer interview and survey. The study analyzes daily report data to deduct crucial processes affecting masonry work which has been investigated to be one of preliminary processes conducted at the beginning of finish work.

• 대한한의진단학회지
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• 제19권3호
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• pp.185-193
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• 2015

Objectives The purpose of this report is to represent decubitus ulcer(pressure sore) improved by carbon arc and oriental medicine. Methods Patients with decubitus ulcer were treated with carbon arc, acupuncture, herbal medicine and simple dressing. Laser was irradiated at ulcer site once a day for 5 hour, using cored carbon number 3000,3002. Simple dressing with wound cleansing was performed to prevent reinfection. Herbal medicine and acupuncture treatment were applied to improve patients' general condition. Ulcer sizes and aspects were carefully checked by one week. Results Sizes of the decubitus ulcer decreased. Stage of ulcer was improved from stage 3 to stage 2. These results show that carbon arc may play a role in treating the decubitus ulcer with oriental medicine.

• Imaging Science in Dentistry
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• 제50권1호
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• pp.65-71
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• 2020

Ossifying fibroma is a slow-growing benign neoplasm that occurs most often in the jaws, especially the mandible. The tumor is composed of bone that develops within fibrous connective tissue. Some ossifying fibromas consist of cementum-like calcifications, while others contain only bony material; however, a mixture of these calcification types is commonly seen in a single lesion. Of the craniofacial bones, the mandible is the most commonly involved site, with the lesion typically inferior to the premolars and molars. Ossifying fibroma of the jaw shows a female predominance. Some reports of ossifying fibroma have been published in the literature; however, this report continues the research on this topic by detailing 3 types of ossifying fibroma findings on panoramic radiographs and cone-beam computed tomographic images of 4 patients. The radiographs of the presented cases could help clinicians understand the variations in the radiographic appearance of this lesion.