• 한국전자거래학회지
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• 제15권1호
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• pp.17-37
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• 2010

최근 온라인 상품검색기능을 제공하는 여러 사이트에서는 단순하게 특정상품을 검색하거나 신제품에 대한 소개 및 검색 기능뿐만 아니라 가격별 정렬, 제조사별 정렬, 출시일별 정렬 기능을 통해 상품을 판매하는 인터넷 쇼핑몰 사이트로의 연결기능과 함께 상품에 대한 주요 기능설명과 이용자들의 구매후기 등과 같은 다양한 서비스를 제공하고 있어, 온라인 쇼핑을 즐기는 소비자들에게 구매를 위한 준거점으로서 양질의 정보를 제공하고 있다. 본 연구는 온라인 상품 검색사이트에서 제공하는 이용후기의 역할을 살펴보고자 수행되었다. 이를 위해 온라인 상품검색사이트의 이용후기 특성으로 정보제공성과 유용성을 각각 설정하고, 온라인 상품검색사이트의 친숙성과 함께 사이트 신뢰, 만족, 충성도에 미치는 영향력 과정을 확인하기 위해 8개의 연구가설을 설정하였으며, 175명으로부터 자료를 수집, 이를 구조방정식 모형을 이용하여 검증하였다. 그 결과 친숙성과 이용후기의 정보제공성, 유용성 등이 사이트 신뢰, 만족을 경유하여 충성도에 유의적인 영향력을 미치고 있음을 확인하였다. 이를 통해 온라인 상품검색사이트 이용자의 충성도를 높이기 위해서는 사이트 친숙성을 높이는 전략, 제공되는 이용후기의 정보제공성을 높이고 유용성을 높이기 위한 운영전략의 마련이 필요하다 하겠다. 본 연구의 이러한 결과들이 향후 온라인 상품검색사이트를 운영하는 기업에게 많은 도움이 되었으면 한다.

• 대한환경공학회지
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• 제39권9호
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• pp.519-526
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• 2017

본 연구는 영산강 죽산보 상류 퇴적물을 대상으로 퇴적물에 존재하는 무기인의 존재형태를 파악하고 수체에 미치는 잠재적인 가능성을 예측해보고자 실험실 실험을 진행하였다. 이를 위해 현장 퇴적물을 채취하여 7일 동안 배양실험을 진행하였고, 배양 후 퇴적물의 존재형태별 인 및 수층의 총인을 측정하였다. 무기인의 총량은 YS1 지점보다 YS2 지점에서 더 많았으며, 존재형태별 인 중 Al-P와 Fe-P의 비율이 높았다. 두 지점 퇴적물 모두 배양 초기에 비해 배양 7일 후 Al-P, Fe-P 그리고 Ca-P는 증가하였으며, Red-P는 시간에 따라 감소하는 경향을 보였다. 수층의 총인 농도는 YS1 지점에서 배양시간에 따라 증가하는 경향을 보였고, YS2 지점에서는 배양 7일 후 초기에 비해 총인의 농도가 감소하였다. 퇴적물 입자가 조밀한 YS1 지점이 YS2 지점에 비해 수층 총인 농도가 높은 결과로부터 수층의 총인 농도 변화는 퇴적물의 입도에 영향을 받음을 알 수 있었다. 존재형태별 인 중 Fe-P는 수층의 총인 농도와 음의 상관관계를, Red-P는 양의 상관관계를 보였다. 본 연구의 결과로부터, 수층의 총인 농도를 관리하기 위해서는 퇴적물 인의 존재형태별 특성을 지속적으로 모니터링 하는 것의 필요성을 확인할 수 있다.

• Journal of Microbiology and Biotechnology
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• 제10권5호
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• pp.663-669
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• 2000

The fur (ferric uptake regulation) expression vector pMON2064 was modified to produce a Fur-fusion expression vector. A kinker site, factor Xa cleavage site, and several restriction endonuclease sites were introduced to facilitate easy cloning and isolating of the fusion protein. The resulting fusion expression vector, pMONSTER, was then used to make fusion expression vector, pMONSTER, was then used to make fusion proteins with $\beta$-galactosidase and the protease of the human immunodeficiency virus type 1 (HIV-1 PR). Strain SW4020 harboring the Fur $\beta$-galactosidase fusion vector produced blue colonies on a 5-bromo-4-chloro-3-indolyl-$\beta$-D-galactoside plate and the resulting 133 kDa fusion protein reacted with an anti-Fur antibody. The strain harboring the Fur-HIV-1 PR fusion vector produced a 29 kDa fusion protein, which also reacted with an anti-Fur antibody. The Fur-HIV-1 PR fusion protein was purified by a single column application that was designed to isolate the Fur protein. The purified Fur-HIV-1 PR fusion protein digested with factor Xa cleaved a recombinant Gag protein to release smaller fragments, including a p24 capsid protein. The Fur-HIV-1 PR fusion protein itself did not exhibit any proteolytic activity.

• 약학회지
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• 제49권4호
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• pp.260-267
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• 2005

[ $PGE_1$ ] is an endogenous substance of potent vasodialator as well as inhibitor of platelet aggregation. It has been used therapeutically in peripheral arterial occlusive disease and impotence. Intracavernous injection of $PGE_1$ for erectile dysfunction has been established for several years as a treatment option for erectile dysfunction of diverse etiologies, but this mode of administration is limited by penile discomfort, pain at the injection site, inconvenience and noncompliance. As the matter of worse, the $\beta-hydroxy$ moiety of $PGE_1$ is extremely susceptible to dehydration in solution to give inactive $PGA_1$ and $PGB_1$. For the improvement of stability, rapid absorption at action site and the convenience of application, $PGE_1$ was formulated as urethral suppositories of three types of formulations, such as PEG, witepsol, and the mixture of PEG and witepsol. The stability test of $PGE_1$ and the release test in urinary suppositories were performed. Futhermore, the effect of enhancers and vehicle composition on the penetration of $PGE_1$ through excised rat skin was evaluated by permeability coefficient and enhancement ratio.

• 대한간호학회지
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• 제37권1호
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• pp.14-25
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• 2007

Purpose: A user centered web-based mental health management system may be particularly useful in Korea where there is widespread diffusion of personal computers and internet connectivity. The purpose of this paper was to describe the development of a web-based system for mental health management in adolescents using principals of a user centered design. Method: Our design process includes five distinct phases: needs assessment, analysis, design, development/testing/revision, and application release. Results: Web content includes an introduction, information about mental health management in adolescents, self-assessment and guidance, interventions for improving mental health, directory of self-help groups, and counseling and additional community resources. The web site was released using the URL: http://www.baejy.com/youth. Conclusion: The end result was a web based mental health management system for adolescents with a high degree of usability. The author believes that web-based mental health interventions in the future have true potential in helping Koreans who are suffering, or at risk, for mental health problems, particularly because of the stigma related to psychiatric therapy in Korea.

• 한국환경과학회지
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• 제21권9호
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• pp.1069-1078
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• 2012

This study was performed to evaluate the asbestos exposure levels and to calculate excess lifetime cacer risks(ELCRs) in asbestos-containing buildings for maintenance and management. The range of airborne asbestos concentration of 33 buildings was 0.0018 ~ 0.0126 f/cc and one site exceeded indoor air-quality recommended limit 0.01 f/cc. And ELCRs based on US EPA IRIS(Integrated risk information system) model are 1.5E-06 ~ 3.9E-05 levels, and there was no site showed 1.0E-04 (one person per million) level or more, and 11 sites showed 1.0E-05 (one person per 100,000 people) level or more. To prevent the release of asbestos fibers, it needs operation and maintenance of asbestos-containing building materials, and there are some methods such as removal, repairment, enclosure and encapsulation. In conclusion, a risk-based air action level for asbestos in air is an appropriate metric for asbestos-containing building management.

• 한국환경과학회지
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• 제25권11호
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• pp.1555-1562
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• 2016

Concentrations of hydrogen sulfide in ambient air have been measured from January 2014 to June 2016 in a coastal area near the Ulsan National Industrial Complex. The measurement sites were 1 km, 2.6 km, 5.6 km, and 20 km away from a kraft pulp mill, which is located at the most southern edge of the complex. Concentrations above 0.4 ppb were monitored every 5 min and the highest concentration of the day was determined. From a total of 775 measurement days, hydrogen sulfide concentrations > 20 ppb were recorded on 36 and 38 days at the measurement site closest to the mill and the residential area 2.6 km away from the mill, respectively. At the site farthest from the mill, the concentrations were always 20 ppb lower than the malodor regulation for the residential area but sometimes higher than the odor recognition threshold for hydrogen sulfide. Although several emission sources of hydrogen sulfide have been published in the Pollutant Release and Transfer Register of Korea, the kraft pulp mill is considered to be the biggest contributor of atmospheric hydrogen sulfide in the southern coastal area of Ulsan.

• 한국안전학회지
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• 제26권5호
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• pp.105-109
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• 2011

Since a severe accident, which happens in low frequency, can cause serious damages, the interests in off-site consequence analysis for a nuclear power plant have been increased after Chernobyl, TMI and Fukushima accidents. Consequences, which are the effects on health and environment caused by released radioisotopes, are evaluated using MACCS II code based on the method of Level 3 PSA. To perform a consequence analysis for the reference plants, the input data of the code were generated such as meteorological data, population distribution, release fractions, and so on. Using these input data, acute and lifetime dose as an organ, CCDF for early fatalities and latent cancer fatalities, and average individual risk were analyzed by using MACCS II code in this study. These results might contribute to establishing accident management plan and quantitative health object.

• 대한기관식도과학회지
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• 제3권1호
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• pp.61-69
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• 1997

A total of 55 patients underwent surgical managements for postintubation tracheal stenosis from July 1975 through March 1997. All but 8 had received ventilatory assistance. The patients had S cuff lesions, 17 stoma lesions, 7 at both levels, 5 at subglottic lesions. Thirty two patients underwent the sleeve tracheal resection and end-to-end anastomosis. Five patients performed a wedge resection and end-to-end anastomosis. Twenty two patients received the Montgomery T-tube for relief of airway obstruction. Simple excision of granulation tissue was done in 7 patients. Rethi procedures(anterior division of cricoid cartilage, partial wedge resection of lower thyroid cartilage and T-tube molding) were performed in 2 subglottic stenosis patients. And the other subglottic patient was received permanent tracheal fenestration at 1975. The tracheoesophageal fistula patient was done sleeve tracheal resection and end-to-end anastomosis with interrupted double layer closure of esophageal fistula site. Cervical approach was used in 49 cases, cervicomediastinal in 13 cases and median stemotomy In 6 cases. Techniques for obtaining tension-free anastomosis included a cervical neck flexion(15-30$^{\circ}$) in all sleeve resection patients and laryngeal release in one. The length of resection was 1.5 to 5.0 on A total of 41 patients(74.5%) had good(24 patients) or satisfactory(17 patients) results. But in ten cases, the restenosis of anastomosis site which is the most common complication was developed Two of them underwent a second reconstruction and 8 patients required T-tube insertion for airway maintenance. Three patients(5.4%) died. The causes of death were tracheo-innominate artery fistula(2) and sudden obstruction of airway(1).

• Structural Engineering and Mechanics
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• 제69권3호
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• pp.317-326
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• 2019

This research aims to assess the tight seismic risk curve of the intake tower at Geumgwang reservoir by considering the recorded historical earthquake data in the Korean Peninsula. The seismic fragility, a significant part of risk assessment, is updated by using Bayesian inference to consider the uncertainties and computational efficiency. The reservoir is one of the largest reservoirs in Korea for the supply of agricultural water. The intake tower controls the release of water from the reservoir. The seismic risk assessment of the intake tower plays an important role in the risk management of the reservoir. Site-specific seismic hazard is computed based on the four different seismic source maps of Korea. Probabilistic Seismic Hazard Analysis (PSHA) method is used to estimate the annual exceedance rate of hazard for corresponding Peak Ground Acceleration (PGA). Hazard deaggregation is shown at two customary hazard levels. Multiple dynamic analyses and a nonlinear static pushover analysis are performed for deriving fragility parameters. Thereafter, Bayesian inference with Markov Chain Monte Carlo (MCMC) is used to update the fragility parameters by integrating the results of the analyses. This study proves to reduce the uncertainties associated with fragility and risk curve, and to increase significant statistical and computational efficiency. The range of seismic risk curve of the intake tower is extracted for the reservoir site by considering four different source models and updated fragility function, which can be effectively used for the risk management and mitigation of reservoir.