• Tuberculosis and Respiratory Diseases
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• 제65권2호
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• pp.121-124
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• 2008

유육종증의 비강 침범은 드물게 발견되며 폐 침범 없이 비강만 단독으로 침범하는 경우는 더욱 드물게 보고되고 있다. 37세의 여자 환자가 콧물과 비강 폐색을 주소로 내원하였다. 비강 종괴의 조직 검사상 일부분에서 괴사를 동반한 비건락성 육아종으로 나와 폐외 결핵으로 생각하고 9개월간 항결핵제의 투약을 하였다. 그러나 항결핵제 투약 완료 후에 결막 종괴 및 많은 수의 흉곽 내 림프절 비대가 새로이 발견되었고, 결막 종괴에서 시행한 조직 검사상 비강 종괴와 동일한 양상의 비건락성 육아종이 발견되었다. 항결핵제 투약에도 불구하고 임상 증상의 호전이 없었고 비강과 결막 조직 검사에서 비건락성 육아종 소견이 동일하게 보여 최종적으로 유육종증으로 진단 할 수 있었다. 혈청 안지오텐신 전환효소 수치는 상승되어 있었다. 부신피질 호르몬 투여 이후 환자의 증상은 점차 개선되었다.

• Imaging Science in Dentistry
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• 제51권3호
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• pp.243-250
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• 2021

Purpose: The objective of this study was to evaluate the amount of height available for a maxillary sinus augmentation procedure without blocking the ostium and jeopardizing the drainage of the ostiomeatal complex using cone-beam computed tomography (CBCT) imaging. Materials and Methods: A total of 200 sinonasal complexes comprising 100 dentate and 100 edentulous scans were retrospectively assessed using CBCT. Invivo 5.0, a CBCT reconstruction program, was used for image evaluation. The coronal section demonstrating the ostiomeatal complex was selected as a reference view to perform measurements of the sinus. The measurements were done by 2 evaluators in separate sessions. Comparative analyses of measurements were performed between dentate and edentulous patients and between male and female patients. Results: The safe height to which the sinus can be elevated without compromising the integrity of the ostiomeatal complex was calculated for each sinus. In the presence of significant mucosal thickening, the height available for augmentation was calculated by subtracting the height of mucosal thickening from the sinus floor to the location of the ostium. In this study, the available height was approximately 27.05 mm for dentate and 23.40 mm for edentulous patients. The inter-operator reliability was excellent for all the parameters evaluated. Conclusion: This retrospective study with a limited number of patients from a single university-based site shows that CBCT is valuable in evaluating the location and patency of the ostium for planning sinus augmentation procedures for dental implant placement.

• 한방안이비인후피부과학회지
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• 제32권2호
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• pp.59-67
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• 2019

Objectives : The purpose of this study was to analyze the effects of traditional korean medicine treatment on patients with olfactory disorder who did not respond to steroid treatment. Methods : A retrospective chart review was conducted on 16 patients who visited the outpatient clinic with olfactory disorder for over 1 month. The patients were treated with Herbal medicine, acupuncture, electronic moxibustion, intranasal pharmacopuncture, and olfactory training. The treatment effect was evaluated by KVSS I test. Results : There was no significant difference in KVSS I test score according to sex, age, duration of treatment, number of treatment, the days after onset. There was no significant difference in the KVSS I test scores before and after the treatment for the cases of sinonasal disease, head trauma, and idiopathic cases. However, there was a significant difference in cases of post-viral olfactory disorder. Conclusion : Traditional korean medicine may be effective for patients with post-viral olfactory disorder that did not show improvement in steroid treatment.

• Anatomy and Cell Biology
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• 제56권2호
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• pp.179-184
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• 2023

The Functional endoscopic sinus surgery through transnasal approach is a common modality of treatment for disorders of the nasal cavity, paranasal air sinuses as well as cranial cavity. The olfactory fossa (OF) is located along the superior aspect of cribriform plate which varies in shape and depth. This variable measurement of the depth of OF is mostly responsible for greater risk of intracranial infiltration during endoscopic procedures in and around the nasal cavity. The morphology of frontal and ethmoid sinus (ES) vary from simple to complex. This cadaveric study is planned to improve the ability of the otolaryngologist, radiologist to understand the possible morphological variations and plan steps of less invasive "precision surgery" to have a safe and complication free procedures. A total of 37 human head regions were included in the study. For classification of OF, Modified Kero's classification was used. The size, shape and cells of frontal and ES were noted. We found, type II (60.8%) OF was more common followed by type I (29.7%) than type III (9.5%). The shape of frontal sinus was comma shaped (55.4%) followed by oval (18.9%) than irregular (16.2%). Most common two cells type of ES was seen in 50.0% of both anterior and posterior ES. Out of 74 ES, 8.1% of Onodi cells and 14.9% of agger nasi cells were seen.

• The Korean journal of internal medicine
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• 제39권1호
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• pp.86-94
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• 2024

Background/Aims: A catheter is inserted through the nasal cavity during high-resolution esophageal manometry (HRM), which may cause adverse events such as pain or epistaxis. Despite these possible safety considerations, studies on this subject are very limited. We aimed to investigate the usefulness of nasal cavity evaluation before HRM to reduce the risk of adverse events and test failure. Methods: Patients who underwent HRM after consultation with the ear-nose-throat department for nasal evaluation were retrospectively enrolled between December 2021 and May 2022. The included patients had a previous history of sinonasal disease or surgery or had subjective nasal discomfort. All patients answered the Sino-Nasal Outcome Test (SNOT-22) questionnaire, and subjective nasal discomfort was scored using a visual analog scale. Nasal endoscopy and acoustic rhinometry were performed for disease evaluation and volumetric assessment. Results: The analysis included 22 patients with a mean age of 58.9 years. The mean SNOT-22 score was 24.2, and 16 patients (72.7%) complained of subjective nasal obstruction. The HRM catheter was successfully inserted in 20 patients (90.9%), without any significant adverse events. The objective measurement outcomes of acoustic rhinometry and sinus endoscopy did not always correspond to subjective symptoms. Narrowed nasal airways unresponsive to decongestants were observed in two patients with failed catheter insertion. Conclusions: To reduce the risk of adverse events and test failure during HRM, a site-specific questionnaire to evaluate nasal obstruction might be helpful. When nasal obstruction is suspected, objective nasal cavity evaluation could be recommended for the safe and successful performance of HRM.

• Journal of Yeungnam Medical Science
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• 제22권2호
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• pp.191-198
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• 2005

확실한 자기공명영상의 효과를 판정하기 위해서는 아직도 증례가 많이 부족한 것이 사실이지만 본 연구의 결과에서도 알 수 있듯이 반전성 유두종에 있어 술전 자기공명영상으로 종양의 범위와 위치를 구별하는데 탁월한 효과를 확인하였다. 앞으로도 많은 환자를 대상으로 체계적인 연구가 이루어져야 하겠고 향후 지속적인 자기공명영상 촬영술의 발달이 뒷받침 된다면 좀 더 정확한 결과를 얻을 수 있을 것으로 기대된다.

• 대한영상의학회지
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• 제81권6호
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• pp.1377-1388
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• 2020

목적 본 연구의 목적은 비중격 만곡증과 수포성 비갑개가 상악동 부피에 영향을 미치는지 그리고 만성 부비동염의 유병률과 관련성 여부를 분석해보는 것이다. 대상과 방법 이 연구는 2017년 1월부터 2년 동안 부비동 증상을 호소하며 본원 이비인후과를 내원한 환자 중 부비동 컴퓨터단층촬영술을 시행한 209명의 환자들을 후향적으로 분석하였다. 부비동의 부피 측정을 포함한 컴퓨터단층촬영술에 대한 판독은 1명의 영상의학과 의사가 2번 반복하여 시행하였고, 통계적 분석은 SAS 9.4를 사용되었다. 결과 상악동 부피는 우측, 좌측 모두 남자가 여자보다 의미 있게 컸다(p < 0.0001). 또한 수포성 비갑개는 비중격 만곡증의 오목한 부분에서 유의하게 많이 존재하였다(p < 0.0001). 그러나 비중격 만곡증이나 상악동 부비동염과의 관련성은 방향성을 나누어 분석했을 시 서로 유의하지 않았다(p = 0.8756). 또한 수포성 비갑개는 상악동 부비동염(p = 0.3401)이나 상악동 부피와(양측: p = 0.6289, 우측: p = 0.9522, 좌측: p = 0.9201) 연관성이 없었다. 결론 수포성 비갑개는 만곡된 비중격의 반대편에 주로 존재하였다. 그러나 해당 관련성 이외에는, 비중격 만곡증과 수포성 비갑개는 상악동의 부피나 부비동염과는 큰 연관이 없다.

• IMMUNE NETWORK
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• 제22권4호
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• pp.35.1-35.16
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• 2022

Tobacco smoking (TS) has been known as one of the most potent risk factors for airway inflammatory diseases. However, there has been a paucity of information regarding the immunologic alteration mediated by TS in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). To identify the effect of TS, we harvested human tissue samples (never smoker: n=41, current smoker: n=22, quitter: n=23) and analyzed the expression of epithelial-derived cytokines (EDCs) such as IL-25, IL-33, and thymic stromal lymphopoietin. The expressions of Th2 cytokines and total serum IgE showed a type-2 inflammatory alteration by TS. In addition, the epithelial marker E-cadherin and epithelial-mesenchymal transition (EMT)-associated markers (N-cadherin, α-SMA, and vimentin) were evaluated. Histological analysis showed that EDC expressions were upregulated in the current smoker group and downregulated in the quitter group. These expression patterns were consistent with mRNA and protein expression levels. We also found that the local Th2 cytokine expression and IgE class switching, as well as serum IgE levels, were elevated in the current smoker group and showed normal levels in the quitter group. Furthermore, the expressions of E-cadherin decreased while those of N-cadherin, α-SMA, and vimentin increased in the current smoker group compared those in the never smoker group. Taken together, these results indicate that TS contributes to the deterioration of pathogenesis by releasing local EDCs and Th2 cytokines, resulting in EMT in patients with CRSwNP. We verified that alterations of immunological response by TS in sinonasal epithelium can play a vital role in leading to CRSwNP.