• Journal of the Korean Mathematical Society
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• v.35 no.3
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• pp.675-690
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• 1998

A role of singletons in quantum central limit theorems is studied. A common feature of quantum central limit distributions, the singleton condition which guarantees the symmetry of the limit distributions, is revisited in the category of discrete groups and monoids. Introducing a general notion of quantum independence, the singleton independence which include the singleton condition as an extremal case, we clarify the role of singletons and investigate the mechanism of arising non-symmetric limit distributions.

• MALSORI
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• no.64
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• pp.53-76
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• 2007

This study investigates phonation types of Korean obstruents associated with the vowels immediately following singletons or geminates in intervocalic positions. F0, H1-H2, and spectral tilt were measured from the 20 ms segment at the onset of the vowels for the tokens of /paCa/ and /paCCa/, where Cs are of the same manner and place of articulation. The results showed a remarkable change in the values of F0, H1-H2, and spectral tilt as the preceding obstruents shifts from the lenis singletons to the lenis geminates, which suggests that the spectral characteristics of the vowels following the lenis geminates are not different from those of the vowels following fortis singletons or geminates. Significantly enough, this study adds data about the spectral characteristics of Korean phonation types.

• Phonetics and Speech Sciences
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• v.14 no.3
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• pp.67-76
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• 2022

This paper presents two experiments examining different gemination behavior of English affixes. Experiment 1 focused on geminates through affixation with im-, un-, -ness, and -ly. The English group articulated geminates with longer absolute and relative durations than singletons for im-, un-, and -ness, but there was no difference for -ly. This suggests that -ly words are more likely to be perceived as whole words, and that -ly is less decomposable. Furthermore, un- geminates exhibited longer absolute and preceding vowel durations than im- geminates, suggesting that im- is more decomposable than un-. However, the Korean group produced geminates with longer absolute and relative durations than singletons for all im-, un-, -ness, and -ly, and produced comparable absolute durations of im- and un- geminates. Experiment 2 investigated different gemination behaviors of locative and negative im- prefixes. The English group showed durational contrast between geminates and singletons only for negative im-, indicating that locative im- is not easily separated from stem. However, the Korean group produced longer absolute and relative durations for geminates than for singletons for both locative and negative im-. According to the findings of Experiments 1 and 2, affix decomposability is less likely to influence Korean speakers' English affix gemination, and spellings may have a greater influence.

• Speech Sciences
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• v.1
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• pp.83-101
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• 1997

This paper aims at exploring a putative positional neutralization produced at the phonetics/phonology interface. It was designed to determine whether Korean intervocalic laryngeal consonants are phonetically distant from geminates, plain consonants, or laryngeal consonants in consonant clusters. It was found that the contrast between laryngeal singletons and geminates was neutralized intervocalically, and that both of these were patterned with heteroganic consonant sequences rather than with plain singletons.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1993.06a
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• pp.1266-1269
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• 1993

The paper introduces a new method for fuzzy processing. The method allows handing a piece of information lost in the classic fuzzification process, and thus neglected by other methods. Processing the result after fuzzification is sustained by the interpretation that the input-output set mapping, specified by the IF-THEN rules, can be regarded as a direct mapping of their corresponding alpha-cuts. Processing involves just singletons as intermediary results, the final result being a combination of singletons obtained from fired rules.

• Phonetics and Speech Sciences
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• v.9 no.4
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• pp.19-25
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• 2017

The current study focused on the production of geminate nasal consonants across different word boundary types in Korean as a function of speech style to investigate whether temporal properties are preserved across varying speaking rates. Assimilated geminates in Korean, known as true geminates, are produced with distinctively longer consonant duration compared to singletons. Despite a large body of literature for geminates across different languages, geminates in Korean have been relatively less investigated with respect to the durational patterns in relative terms and temporal variabilities. In this study, singletons, word-internal geminates and word-boundary (fake) geminates produced by ten native Seoul Korean speakers were compared in terms of absolute consonant closure duration, preceding vowel duration, the relative ratios (consonant-to-preceding vowel duration) as well as the temporal variabilities in speech production. The results showed that word-internal geminates were produced with longer consonant duration and greater temporal variabilities than singletons and word-boundary geminates in absolute duration, indicating relatively greater flexibility in timing. However, only word-internal geminates were produced with distinctively longer consonant duration with significantly lower variability in relative duration regardless of speech styles. The results provide some insight into the representation of temporal information in the production of Korean geminate consonants.

• Journal of Microbiology and Biotechnology
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• v.27 no.5
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• pp.916-924
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• 2017

Eighty-five Enterococcus faecalis isolates collected from animals (40 isolates), meju (a Korean fermented soybean product; 27 isolates), humans (10 isolates), and various environmental samples (8 isolates) were subjected to multilocus sequence typing (MLST) to identify genetic differences between samples of different origins. MLST analysis resulted in 44 sequence types (STs), and the eBURST algorithm clustered the STs into 21 clonal complexes (CCs) and 17 singletons. The predominant STs, ST695 (21.1%, 18/85) and ST694 (9.4%, 8/85), were singletons, and only contained isolates originating from meju. None of the STs in the current study belonged to CC2 or CC9, which comprise clinical isolates with high levels of antibiotic resistance. The E. faecalis isolates showed the highest rates of resistance to tetracycline (32.9%), followed by erythromycin (9.4%) and vancomycin (2.4%). All isolates from meju were sensitive to these three antibiotics. Hence, MLST uncovered genetic diversity within E. faecalis, and clustering of the STs using eBURST revealed a correlation between the genotypes and origins of the isolates.

• Journal of Microbiology and Biotechnology
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• v.22 no.7
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• pp.902-906
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• 2012

Expressed sequence tags (ESTs) from the Antarctic green algae Pyramimonas gelidicola were analyzed to obtain molecular information on cold acclimation of psychrophilic microorganisms. A total of 2,112 EST clones were sequenced, generating 222 contigs and 219 singletons, and 200 contigs and 391 singletons from control ($4^{\circ}C$) and cold-shock conditions ($-2^{\circ}C$), respectively. The complete EST sequences were deposited to the DDBJ EST database (http://www.ddbj.nig.ac.jp/index-e.html) and the nucleotide sequences reported in this study are available in the DDBJ/EMBL/GenBank. These EST databases of Antarctic green algae can be used in a wide range of studies on psychrophilic genes expressed by polar microorganisms.

• Genomics & Informatics
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• v.8 no.3
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• pp.131-137
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• 2010

Genome-wide association studies (GWASs) have greatly contributed to the identification of common variants responsible for numerous complex traits. There are, however, unavoidable limitations in detecting causal and/or rare variants for traits in this approach, which depends on an LD-based tagging SNP microarray chip. In an effort to detect potential casual and/or rare variants for complex traits, such as type 2 diabetes (T2D) and triglycerides (TGs), we conducted a targeted resequencing of loci identified by the Korea Association REsource (KARE) GWAS. The target regions for resequencing comprised whole exons, exon-intron boundaries, and regulatory regions of genes that appeared within 1 Mb of the GWA signal boundary. From 124 individuals selected in population-based cohorts, a total of 0.7 Mb target regions were captured by the NimbleGen sequence capture 385K array. Subsequent sequencing, carried out by the Roche 454 Genome Sequencer FLX, generated about 110,000 sequence reads per individual. Mapping of sequence reads to the human reference genome was performed using the SSAHA2 program. An average of 62.2% of total reads was mapped to targets with an average 22X-fold coverage. A total of 5,983 SNPs (average 846 SNPs per individual) were called and annotated by GATK software, with 96.5% accuracy that was estimated by comparison with Affymetrix 5.0 genotyped data in identical individuals. About 51% of total SNPs were singletons that can be considered possible rare variants in the population. Among SNPs that appeared in exons, which occupies about 20% of total SNPs, 304 nonsynonymous singletons were tested with Polyphen to predict the protein damage caused by mutation. In total, we were able to detect 9 and 6 potentially functional rare SNPs for T2D and triglycerides, respectively, evoking a further step of replication genotyping in independent populations to prove their bona fide relevance to traits.

• Korean Journal of Agricultural Science
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• v.45 no.4
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• pp.583-590
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• 2018

Genus Typha L. (Typhaceae; Cattail in common) is one of the hydrophytic plants found in semi-aquatic regions. About nine to 18 species of the genus exist all over the world. In Korea, the most commonly found cattail species are T. laxmanni and T. angustifolia. The aim of this study was to prepare a cDNA library and sequences and analyze expressed sequence tags (ESTs) from these species, T. laxmanni and T. angustifolia. In the case of T. laxmanni, we observed that 715 out of 742 ESTs had high quality sequences, whereas the remaining 27 ESTs were low quality sequences. In this study, we identified 77 contigs, 393 unassembled clones and 65.7% singletons. Furthermore, in the case of T. angustifolia, we recorded 992 high quality EST sequences, and by excluding 28 low quality sequences from among them, we retrieved 120 contigs, 348 unassembled clones and 48.9% singletons. The basic local alignment search tool (BLAST) and Kyoto encyclopedia of genes and genomes (KEGG) database results enabled us to identify the functional categories, i.e., molecular function (16.5%), biological process (22.2%) and cellular components (61.3%). In addition, between these two species, the no hits and anonymous genes were 4.2% and 11.7% and 6.2% and 11.2% in T. laxmanni and T. angustifolia, respectively, based on the BLAST results. The study concluded that they have certain species-specific genes. Hence, the results of this study on these two species could be a valuable resource for further studies.