• Bulletin of the Korean Chemical Society
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• 제27권9호
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• pp.1346-1352
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• 2006

We describe an effective method of microchip electrophoresis (ME) based on single strand conformation poly-morphism (SSCP) analysis to rapidly detect the point mutation, Leu72Met, in a human obesity gene. The 207-bp dsDNA in the Leu72Met region, an estimate of the child obesity DNA mutant, was amplified by polymerase chain reaction (PCR) and submitted to a conventional glass microchip analysis with a sieving matrix of 1.75% poly(vinylpyrrolidone) (Mr 1 300 000), 1.0% poly(ethyleneoxide) (Mr 600 000) and 5.0% w/w glycerol. When combined with base stacking (BS) with hydroxide ions, the SSCP-ME provided rapid analysis as well as sensitive detection. The detection sensitivity was effectively enhanced in the OH- concentration range of 0.01-0.025 M NaOH. The sensitivity and speed of this ME-based SSCP methodology for the rapid detection of Leu72Met point mutations makes this an attractive method for diagnosing childhood obesity in a clinical diagnostic laboratory.

• Clinical and Experimental Pediatrics
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• 제56권2호
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• pp.90-93
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• 2013

Congenital coronary arteriovenous fistulas (CCAFs) are rare coronary artery abnormalities in which blood is shunted into a cardiac chamber or great vessel. If the fistula itself is large and tortuous, it is generally recommended to occlude the fistula to prevent several complications. In approaches of transcatheter occlusion, the transvenous approach is preferred over the transarterial approach. The transvenous approach would enable the cannulation of a relatively larger catheter or sheath without potential damage to the femoral vessels or normal coronary arteries, which can occur in the transarterial approach. The transvenous approach may also minimize the blind pouch after releasing the devices. Herein, we report the success of transvenous proximal closure of a CCAF using an Amplatzer vascular plug (AVP) in a 3-year-old patient with cardiomegaly. Complete occlusion was achieved by a single AVP and thrombus formation of the distal aneurysmal portion of the fistula. We suggest that this strategy of closing the proximal end with a dilated fistula using a single AVP by the transvenous approach may be a good option in treating CCAFs in a young child.

• 가정과삶의질연구
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• 제30권3호
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• pp.179-192
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• 2012

The purpose of this study is to investigate the variable factors influencing children's interpersonal relationship skills and analyze the effects of marital perspective-taking ability, managing responses of young children and emotional intelligence on the interpersonal relationship skills of children. The study subjects were young children aged from four to seven attending private kindergartens or public day care centers in Seoul or Kyeongki-do and their mothers. The results are as follows : 1) First, marital perspective-taking abilities were indicated higher on boys than girls, children in a full-day program than those in a half-day program, university graduates or higher degree holders than collage graduates, single-income families than double-income families. In case of managing responses of young children, boys showed high avoidance of offensive disposition and girls showed high emotions dissipation. Also, young children in a full-day program showed non-responses on managing responses but high responses on emotions dissipation, and children of mothers with bachelor's degree or higher education showed support and children from double-income family showed no responses in high. Moreover, emotional intelligence of young children in a full-day program was higher than that of children in a half-day program, interpersonal relationship skills were showed higher on girls than boys, half-day children than full-day ones, children from single-income family than those from double-income family. 2) Meaningful relationships were indicated between these variables; managing responses of young children, emotional intelligence and interpersonal relationship skills by partly showing correlations. 3) Children in a half-day program with low in emotions dissipation, non-responses, offensive dispositional managing responses but high on Avoid, emotional intelligence showed high interpersonal relationship skills.

• 식품보건융합연구
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• 제6권3호
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• pp.23-29
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• 2020

Blood transfusion in the neonatal period remains a therapeutic act, that no one dares to consider it as perfectly innocuous and that it is advisable to make rare, considering its risks as well immunological as infectious. The present work is a retrospective study, conducted in neonatal intensive care unit, in the University Hospital MOHAMED VI, Marrakech, during the period from January 1^st to December 31^st, 2019. All newborns were included in this work, who received one or multiple transfusions of red blood cells (RBC). Our study covered 60 neonates with a total of birth: 794 neonates, with a prevalence of 7.55%, hospitalized for various indications (60% of newborns were at term, 31.7% premature and 8, 33% were post-mature. The majority of transfusion procedures were performed during the first week of life. This is explained by the frequency of haemolytic anemias by fœto-maternal incompatibility. The main indications for transfusion were haemolysis, anemic syndrome and haemorrhagic syndrome. The average number of transfusion episodes was 1.95 +/- 1.47 per patient. Newborns were polytransfused in 18.33% of cases. A single transfusion accident was found in our study. However, we did not observe a correlation between the maternal diseases, the state of the newborn, and the transfusional indication.

• 한국가족관계학회지
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• 제22권3호
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• pp.47-72
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• 2017

Objectives: Do husbands with working wives share domestic labor more equally than husbands with unemployed housewives? Is the husband's contribution sufficient enough to satisfy his wife? These questions have long inspired many researchers to find ways to more accurately estimate husband's domestic contributions and narrow the emotional gap following the different threshold of satisfaction within couples, but not without some limits. This study attempted to figure out an answer to the above-mentioned subject by using time diaries of Korean married couples with a preschooler as their first-born child and relying on the typology of husbands' sharing of housework and childcare, which allowed me to overcome some limitations of prior research. Method: I analyzed a total of 1,716 diaries of 858 married couples from 2014 Korea Time Use Survey with descriptive statistics, t-test, cluster analysis, and multinomial logit. Results: Analytic results showed that husbands in dual-earner households did share domestic labor more equally than husbands in single-earner households, but there were different types of husband's contribution depending on time they spent in housework and childcare. While more than half of husbands with employed wives shared more or less than ten percent of domestic labor, the rest were divided into one group of husbands who shared both housework and childcare more heavily and evenly, and another group who were mainly involved in childcare duties. It is interesting that husbands who made the least contributions to domestic labor were not the ones with the lowest level of satisfaction with their sharing of household labor, whereas their wives were deeply dissatisfied, leading to a huge emotional gap within couples. Conclusion: Identifying factors associated with the three different types allowed me to find a point of intervention to narrow the emotional gap that is likely to harm the marital relationship if left unattended to.

• PNF and Movement
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• 제6권2호
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• pp.19-30
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• 2008

Purpose : This study was performed for find out temporal spatial parameter of the gait according to age. Method : Four groups of healthy people were allocated randomly in this study : group I(little child, 15), group II(child, 18) and group III(young people, 17), group(elder people, 16). This study was performed from 01 December to 31 December in 2007. Results : The results were as follows : 1. The swing phase was the longest group II, group IV was the shortest. Each groups, there was significant difference in swing phase(p<.05). 2. The stance phase was the longest group IV, group II was the shortest. Each groups, there was significant difference in stance phase(p<.05). 3. The single support time was the longest group II, group IV was the shortest. Each groups, there was significant difference in single support time(p<.05). 4. The double support time was the longest group IV, group II was the shortest. Each groups, there was significant difference in double support time(p<.05). 5. The gait velocity was the fastest group II, group I was the slowest. Each groups, there was significant difference in gait velocity(p<.05). 6. The toe in/out was very increased group IV, group I was very decreased. Each groups, there was significant difference in toe in/out(p<.05). 7. The cadence was the highest group I, group IV was the lowest. Each groups, there was significant difference in cadence(p<.05). 8. The step length was the longest group III, group I was the shortest. Each groups, there was significant difference in step length(p<.05). 9. The step length asymmetry ratio was the highest group IV, group III was the lowest. Each groups, there was no significant difference in step length asymmetry ratio(p>.05). 10. The single support time asymmetry ratio was the highest group I, group IV was the lowest. Each groups, there was no significant difference in single support time asymmetry ratio (p>.05). 11. The FAP was the highest group III, group I was the lowest. Each groups, there was significant difference in FAP(p<.05).

• 한국사회복지학
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• 제68권3호
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• pp.51-71
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• 2016

이 연구의 목적은 한국을 포함한 OECD 주요국을 대상으로 사회구조적 요인, 복지제도, 노동시장 및 정치제도 등 독신모가구 빈곤의 국가 간 다양성에 영향을 끼치는 거시적 원인을 규명하는 것이다. 1981년부터 2012년 기간에 대해 불균형패널설계(unbalanced panel design)방법을 적용한 결합시계열회귀분석을 실시했다. 연구결과 독신모가구의 빈곤율은 국가 간 다양성이 현저했다. 1인당GDP는 빈곤위험감소에 기여하지 못했고, 여성고용율과 15세미만 아동비율은 빈곤위험을 증가시켰다. 전체사회복지지출, 아동에 대한 현금지출, 노조조직률, 정규직에 대한 고용보호, 비례대표선거제도, 누적좌파내각, 누적여성의석수는 독신모가구의 빈곤위험을 감소시키는 요인으로 나타났다. 한국은 경제성장 일변도와 노동시장유연화 위주의 탈빈곤전략에서 탈피해 보편적 복지제도, 아동에 대한 복지급여와 일-가정양립정책을 확대할 필요가 있다. 나아가 노조조직률향상과 고용보호확대 등 조정된 노동시장제도를 설계하고, 비례대표선거제도 등 합의제정치모델을 도입해 좌파정치세력과 여성의 정치적 대표성을 확립할 필요가 있다.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2004년도 봄 학술발표논문집 Vol.31 No.1 (A)
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• pp.16-18
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• 2004

Single system image(SSI) have been the mainstay high-performance computing for many years. SSI requires the integration and aggregation of all types of resources in a cluster to present a single interface to users. In this paper, we describe a cluster computing architecture with the concept of single process space(SPS) where all processes share a uniform process identification scheme. With SPS, a process on any node can create child process on the same or different node or communicate with any other process on a remote node, as if they are on a single node. For this purpose, SPS is built with the support of unique cluster-wide pid, signal forwarding, and remote fork. We propose a novel design of SPS cluster which addresses the scalability and flexibility problem of traditional clusterwidely unique pid implementation by using blocked pid assignment. We have implemented this new design of SPS cluster, and we demonstrate its performance by comparing it to Beowulf distributed process space. Benchmark performance results show that our design of SPS cluster realized both scalability and flexibility that are essential to building SPS cluster.

• Advances in pediatric surgery
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• 제20권2호
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• pp.48-52
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• 2014

Purpose: Currently the substantial clinical benefits of single-port laparoscopic appendectomy (SLA) over conventional three-port laparoscopic appendectomy (CLA) are equivocal. The aim of this study was to compare surgical outcomes between SLA and CLA in children with acute appendicitis. Methods: A single blind prospective randomized single center study was performed to compare the surgical outcomes of SLA and CLA. A total of 105 patients were randomized and various parameters were analyzed, 52 patients with SLA and 53 patients with CLA between July 2013 and March 2014. Patients with sonographically confirmed acute appendicitis were randomly assigned to receive either SLA or CLA. The outcome measurements were operating time, wound complication, and intraperitoneal morbidities, postoperative pain score and cosmetic result score. Results: Operating time is significantly longer in SLA ($70.4{\pm}26.7$ minutes vs. $58.0{\pm}23.4$ minutes; p=0.016). There were no significant differences in the postoperative wound complication rate and intraperitoneal morbidities between two groups. There were no significant differences in postoperative resting pain score ($6.6{\pm}2.5$ vs. $6.3{\pm}2.5$; p=0.317) and activity pain score ($6.9{\pm}2.4$ vs. $6.3{\pm}2.5$; p=0.189), and the cosmetic result score ($9.2{\pm}1.1$ vs. $9.1{\pm}1.4$; p=0.853). Conclusion: Although SLA would be a safe and feasible procedure in children, SLA could not demonstrate the clear benefit over CLA.

• 가족자원경영과 정책
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• 제25권1호
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• pp.113-132
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• 2021

지금까지의 한부모가족에 대한 연구들의 대다수는 미혼 한부모가족의 형성사유를 구분하지 않아, 청소년한부모를 특정하여 직접 자료조사를 한 연구는 많지 않다. 본 연구의 목적은 청소년부모의 임신, 출산, 양육이 안전하게 이루어지도록 지원하기 위한 정책 개발의 기초 자료를 청소년부모의 양육과 관련한 실태조사를 통해 얻고자 한다. 그러나 현실적으로 청소년부모를 대상으로 하기에는 어려움이 따르므로 동일한 문제를 내포한 10대에 첫 자녀를 출산한 미혼한부모를 대상으로 선정하였다. 연구목적을 위하여 설정한 연구문제는 '첫째, 이들의 기본적인 특성은 어떠한가. 둘째, 임신에서 양육 초기의 실태는 어떠한가. 셋째, 자녀 양육의 실태는 어떠한가. 넷째, 자립의 가능성은 어떠한가' 이다. 본 연구는 청소년부모의 지원근거를 마련하기 위하여 10대에 첫 자녀를 출산한 미혼한부모를 대상으로 임신에서 출산, 양육초기까지의 일련의 과정을 직접 조사를 통해 탐색한 연구로서 기존의 연구들과 차별점을 갖고 있으며, 비양육자인 자녀의 생부의 역동을 함께 추측할 수 있는 자료를 제시하였다. 또한 저출산의 극복이라는 중차대한 국가의 과업에서 청소년 산모의 건강권을 바탕으로 아동의 건강한 성장을 함께 논의하였다는 점에서 의미가 있다. 자녀를 출산하고 양육하는 일은 개인, 사회가 함께 고민하여야 하며, 그 과정에서 아이 생부에 관한 사회의 무관심을 환기시키고 아이 생부를 양육에 참여할 수 있도록 하는 방향으로의 전환을 모색할 필요가 있다. 청소년부모와 미혼부의 존재를 인정하고 이들을 다양한 가족의 하나로 기능할 수 있도록 하기 위하여 청소년복지지원법과 저출산고령사회기본법에서 청소년부모에 대한 지원의 근거가 명시되어야 하며, 10대의 청소년으로서 부모역할을 수행하는 부모, 한부모들에 대해서는 가정의 형태에 관계없이 이용가능한 시스템의 도입과 10대 부모를 대상으로 하는 자녀양육과 관련한 정보 및 양육프로그램이 전문가에 의해 개발되어야 하며 이를 포괄하는 가족정책의 수립과 가족자원과 지역자원을 적용할 수 있는 더욱 구체적인 후속 연구들이 필요함을 제시하였다.