• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2017년도 춘계학술대회 논문집
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• pp.95.1-95.1
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• 2017

In this study, it has been tried to make the single Mo-Cu alloying targets with the Cu showing the best surface hardness that was determined by investigation on the coatings with the double target process. The single alloying targets were prepared by powder metallurgy methods such as mechanical alloying and spark plasma sintering. The nanocomposite coatings were prepared by reactive magnetron sputtering process with the single alloying targets in $Ar+N_2$ atmosphere. The microstructure changes of the Mo-Cu-N coatings with diverse Cu contents were investigated by using XRD, SEM and EDS. The mechanical properties of the coatings were evaluated by using nano-indentor, scratch test, and ball on disc methods. Especially, the coated samples were tested by using various lubricating oil to compare the property of anti wear-resistance. In this study, the nano-composite MoN-Cu coatings prepared using an alloying target was eventually compared with the coatings from the multiple targets.

• 대한지역사회작업치료학회지
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• 제8권2호
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• pp.15-28
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• 2018

목적 : 본 연구는 뇌졸중 환자를 대상으로 한 단일대상연구의 특성을 파악하고 질적 수준을 알아보고자 하였다. 연구방법 : 국가과학기술정보센터(NDSL), 누리미디어(DBpia), 학술연구정보서비스(RISS), 한국학술정보(KISS), 국회도서관의 원문제공 서비스를 이용하여 2002년부터 2017년 까지 발간된 논문 중 뇌졸중', '편마비', '단일대상연구', '단일사례연구', '응용행동분석' 을 주요검색용어를 사용하여 검색하였다. 선별과정을 거쳐 총 24편의 단일대상연구 논문을 선별하여 연구방법과 연구 설계의 질적 수준을 분석하였다. 결과 : 연구 설계 방법으로는 ABA설계가 가장 많았다. 1명이 12(50.0%)으로 가장 많았고, 3명이 8(33.3%)으로 두 번째로 많은 것으로 나타났다. 독립변인으로는 상상훈련이 가장 많이 사용되었다. 종속변인은 상지기능과 편측무시가 가장 많았다. 또한 '기억력', '시각적 주의력', '연하 곤란', '시각-운동 협응', '균형능력', '일상생활활동', '부종' 등의 다양한 목표행동으로 연구가 이루어졌다. 또한 모든 종속 변인에서의 긍정적인 효과가 있는 것으로 나타났다. 질적 수준은 1개 연구를 제외한 연구들이 중간수준 이상인 것으로 나타났다. 결론 : 본 연구는 단일대상 연구 수행 시 갖추어야 할 항목들에 대한 분석하였다는 것에 학문적의의가 있고, 후속연구에서는 본 연구 결과를 바탕으로 지역사회나 임상현장에서 연구를 수행하고 있는 연구자들에게 미약하나마 근거중심설계를 확립하여 양질의 단일대상연구를 수행할 수 있기를 바란다.

• Journal of Microbiology and Biotechnology
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• 제30권10호
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• pp.1583-1591
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• 2020

CRISPR/Cpf1 has emerged as a new CRISPR-based genome editing tool because, in comparison with CRIPSR/Cas9, it has a different T-rich PAM sequence to expand the target DNA sequence. Single-base editing in the microbial genome can be facilitated by oligonucleotide-directed mutagenesis (ODM) followed by negative selection with the CRISPR/Cpf1 system. However, single point mutations aided by Cpf1 negative selection have been rarely reported in Corynebacterium glutamicum. This study aimed to introduce an amber stop codon in crtEb encoding lycopene hydratase, through ODM and Cpf1-mediated negative selection; deficiency of this enzyme causes pink coloration due to lycopene accumulation in C. glutamicum. Consequently, on using double-, triple-, and quadruple-base-mutagenic oligonucleotides, 91.5-95.3% pink cells were obtained among the total live C. glutamicum cells. However, among the negatively selected live cells, 0.6% pink cells were obtained using single-base-mutagenic oligonucleotides, indicating that very few single-base mutations were introduced, possibly owing to mismatch tolerance. This led to the consideration of various target-mismatched crRNAs to prevent the death of single-base-edited cells. Consequently, we obtained 99.7% pink colonies after CRISPR/Cpf1-mediated negative selection using an appropriate single-mismatched crRNA. Furthermore, Sanger sequencing revealed that single-base mutations were successfully edited in the 99.7% of pink cells, while only two of nine among 0.6% of pink cells were correctly edited. The results indicate that the target-mismatched Cpf1 negative selection can assist in efficient and accurate single-base genome editing methods in C. glutamicum.

• 대한방사선기술학회지:방사선기술과학
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• 제39권4호
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• pp.631-636
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• 2016

공간 분해능을 평가하기 위해서 이제까지는 일정하게 두 물체의 간격(이중 표적)을 근접한 것부터 점점 떨어진 간격으로 만들어진 테스트 패턴이나 팬텀을 이용하였다. 이러한 방법으로 공간분해능을 평가하면 분해능은 테스트용으로 제작된 팬텀에 있는 표적 간격으로 제한된다. 본 연구는 이러한 문제를 극복하고자 1개의 단일 표적으로 공간 분해능을 간편하게 측정할 수 있는 새로운 방법을 제안하고 검증한 것이다. 이를 위해 PSF 및 JND를 이용하여 공간 분해능을 추정하는 개념을 제시하였다. 이렇게 유도된 공간 분해능 추정 이론을 검증하기 위해, 상용 팬텀을 이용하여 실험하였다. 실험으로 얻어진 디지털 영상에서 라인 픽셀 프로파일을 구하기 위해 만든 LabVIEW 프로그램을 이용하여 분석한 결과, 본 연구에서 유도한 단일 표적을 이용한 공간 분해능 추정 이론과 실험적으로 일치하는 것을 알 수 있었다. 실험 결과로 디지털 영상에서 공간분해능의 상대적 평가는 단일 표적을 가지고도 충분하다는 것을 증명할 수 있었다. 따라서 단일 표적 공간분해능 평가법을 이용하면 이제까지 사용되어 왔던 이중 표적을 이용한 공간분해능 평가의 한계를 극복할 수 있다.

• 대한가정학회지
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• 제40권3호
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• pp.83-97
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• 2002

This study estimates the consumption needs of preretired households through target replacement ratio approach. Based on the Life Cycle Model, this study used the household expenditure function to derive the target replacement ratio appropriate for each household. The target replacement ratio is estimated using the 1996 National Survey of family Income and Expenditure by National Statistical Office. The estimated target replacement ratio was 82.4% for married couple households, and 85.1% for single households. Total retirement consumption needs during entire retirement period was 161,620,000 won for married couple households, and 50,532,039 won for single households.

• 대한임베디드공학회논문지
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• 제17권1호
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• pp.67-76
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• 2022

Monostatic/Bistatic inverse synthetic aperture radar (ISAR) images are two-dimensional radar cross section (RCS) distributions of a target. When there are many targets in a single radar beam, ISAR images are generated with targets overlapped, so it is difficult to perform the targets identification using the trained database. In addition, it is inefficient to perform target identification using only single monostatic and bistatic ISAR images separately because each method has its own advantages and weaknesses. Therefore, this paper analyzes multiple targets identification performances using monostatic/bistatic ISAR images and proposes a method of identification through fusion of two ISAR images. To identify multiple targets, we use image combination technique using trained single target images. Simulation results show effectiveness of proposed method.

• Nuclear Engineering and Technology
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• 제43권1호
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• pp.13-18
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• 2011

In this study, simulations were done of a 661.6 keV line from a point source of $^{137}Cs$ housed in a lead shield. When increasing the scattering angle from 60 to 120 degrees with a 6061 aluminum alloy target placed at angles of 30 and 45 degrees to the incident beam, the spectra showed that the single scattering component increases and that the multiple scattering component decreases. The investigation of the single and multiple scattering components was carried out using a MCNP5 simulation code. The component of the single Compton scattering photons is proportional to the target electron density at the point where the scattering occurs. The single scattering peak increases according to the thickness of the target and saturates at a certain thickness. The signal-to-noise ratio was found to decrease according to the target thickness. The simulation was experimentally validated by measurements. These results will be used to determine the best conditions under which this method can be applied to testing electron densities or to assess the thickness of samples to locate defects in them.

• 한국표면공학회지
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• 제49권4호
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• pp.368-375
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• 2016

MoN-Cu thin films were prepared to achieve appropriate properties of high hardness and low friction coefficient, which could be applied to automobile engine parts for reducing energy consumption as well as solving wear problems. Composite thin films of MoN-Cu have been deposited by various processes using multiple targets such as Mo and Cu. However, those deposition with multiple targets revealed demerits such as difficulties in exact control of composition and homogeneous deposition. This study is aiming for suggesting an appropriate process to solve those problems. A single alloying target of Mo-Cu (10 at%) was prepared by powder metallurgy methods of mechanical alloying (MA) and spar plasma sintering (SPS). Thin film of MoN-Cu was then deposited by magnetron sputtering using the single alloying target of Mo-Cu (10 at%). Properties of the resulting MoN-Cu thin film were examined and compared to those of MoN-Cu thin films prepared with double targets of Mo and Cu.

• 한국컴퓨터정보학회논문지
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• 제16권9호
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• pp.155-162
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• 2011

레이더에서 목표물을 예측하기위해서 입사 방향 추정 방법을 사용한다. 본 논문에서는 적응 배열 입사 방향 방법과 단일 지향 오차 입사 방향 추정방법을 사용하여 목표물에 대한 입사방향을 추정하였다. 적응 배열 입사 방향 방법으로 주엽 재밍과 부엽 재밍을 제거하여 목표물에 대한 신호 입사 방향을 추정하였다. 단일 지향 방법은 신호 입사 방향의 지향오차가 크기 때문에 목표물의 정확한 추정은 어렵다. 원하는 목표 신호를 수신하기 위해서는신호의 입사 방향과 지향방향사이에 지향오차가 거의 없어야 한다. 입사 방향 추정시 공분산을 구하기 위해서 생기는 지연 시간문제와 단일 지향조건을 이용하여 발생하는 지향오차 문제를 감소시켰다. 본 논문에서는 시뮬레이션을 통하여 제안된 입사 방향 추정방법이 기존의 방법에 비해 목표물 추정면에서 우수함을 보인다.

• 한국음향학회:학술대회논문집
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• 한국음향학회 2004년도 추계학술발표대회논문집 제23권 2호
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• pp.479-482
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• 2004

In this article we consider a single maneuvering target Tracking algorithm in the presence of missing measurements and high clutter environments for multi-sensor target tracking problem. The tracking algorithm is based on the Particle filtering method to predict and update target states. Proposed is the AMM-PF(Auxiliary Multiple Model Particle Filter)[2] method for maneuvering target tracking to improve performance in track estimate and maintenance with a high level of uncertainty. The algorithm we propose is compared to the Extended Kalman Filter(EKF). A simulation study is included.